Virus Evolution

Author : Esteban Domingo,Colin R. Parrish,John J. Holland
Publisher : Elsevier
Page : 573 pages
File Size : 45,7 Mb
Release : 2008-06-23
Category : Science
ISBN : 9780080564968

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Origin and Evolution of Viruses by Esteban Domingo,Colin R. Parrish,John J. Holland Pdf

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Author : Edward C. Holmes
Publisher : Oxford University Press
Page : 267 pages
File Size : 53,5 Mb
Release : 2009-06-25
Category : Language Arts & Disciplines
ISBN : 9780199211128

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The Evolution and Emergence of RNA Viruses by Edward C. Holmes Pdf

While the study of viral evolution has developed rapidly in the last 30 years, little attention has been directed toward linking the mechanisms of viral evolution to the epidemiological outcomes of these processes. This book intends to fill this gap by considering the patterns and processes of viral evolution at all its spatial and temporal scales.

Author : Yechiel Becker
Publisher : Springer Science & Business Media
Page : 223 pages
File Size : 46,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461314073

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Molecular Evolution of Viruses — Past and Present by Yechiel Becker Pdf

The studies presented in this special issue of VIRUS GENES provide information on the two aspects of virus evolution: the ancient evolution of viruses from the time prokaryotic and eukaryotic cells evolved, and the ongoing process of the current molecular evolution of viruses. The studies of many scientists collected in this issue and many more that were published in other scientific journals provide insight into the molecular evolution of viruses as one of nature's mysteries. The use of computer porograms to study the nucleotide sequences of viral genomes, the amino acid compositions of proteins coded by viral genomes, and searches for regulatory mechanisms in viral nucleic acid replication, as well as identities of motifs in proteins of viruses from all families, will provide additional information on the subject. In future issues that will be devoted to this subject, the origin and evolution of RNA and DNA viruses will be further investigated.

Author : Marilyn J. Roossinck
Publisher : Springer Science & Business Media
Page : 227 pages
File Size : 52,8 Mb
Release : 2008-02-23
Category : Science
ISBN : 9783540757634

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Plant Virus Evolution by Marilyn J. Roossinck Pdf

This book provides a comprehensive look at the field of plant virus evolution. It is the first book ever published on the topic. Individual chapters, written by experts in the field, cover plant virus ecology, emerging viruses, plant viruses that integrate into the host genome, population biology, evolutionary mechanisms and appropriate methods for analysis. It covers RNA viruses, DNA viruses, pararetroviruses and viroids, and presents a number of thought-provoking ideas.

Author : Michael G. Cordingley
Publisher : Harvard University Press
Page : 384 pages
File Size : 45,8 Mb
Release : 2017-06-19
Category : Medical
ISBN : 9780674978607

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Viruses by Michael G. Cordingley Pdf

While viruses—the world’s most abundant biological entities—are not technically alive, they invade, replicate, and evolve within living cells. Michael Cordingley goes beyond our familiarity with infections to show how viruses spur evolutionary change in their hosts and shape global ecosystems, from ocean photosynthesis to drug-resistant bacteria.

Author : Esteban Domingo,Peter Schuster,Santiago F. Elena,Celia Perales
Publisher : Springer Nature
Page : 350 pages
File Size : 46,6 Mb
Release : 2023-01-02
Category : Medical
ISBN : 9783031156403

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Viral Fitness and Evolution by Esteban Domingo,Peter Schuster,Santiago F. Elena,Celia Perales Pdf

This book unifies general concepts of plant and animal virus evolution and covers a broad range of topics related to theoretical and experimental aspects of virus population dynamics and viral fitness. Timely topics such as viral mechanisms to cope with antiviral agents, the adaptability of the virus to new hosts, emergence of new viral phenotypes, and the connections between short- and long-term virus evolution are included. By comparing plant and animal viruses, universal mechanisms responsible for fitness variations, viral emergence and disease mechanisms are explored. Although emphasis is put on specific plant and human viral pathogens, relevant similarities and differences to other viruses are highlighted. Additionally, readers will learn more about the adaptability of coronaviruses, including the recently emerged SARS-CoV-2, the causative agent of the COVID-19 pandemic. The book is aimed at students and scientists interested in basic and applied aspects of plant and animal virus population dynamics and evolution.

Author : Adrian J. Gibbs,Charles H. Calisher,Fernando García-Arenal
Publisher : Cambridge University Press
Page : 625 pages
File Size : 47,8 Mb
Release : 1995-10-19
Category : Medical
ISBN : 9780521455336

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Molecular Basis of Virus Evolution by Adrian J. Gibbs,Charles H. Calisher,Fernando García-Arenal Pdf

Advances in molecular biology have enabled leaps forward in the determination of virus phylogenetic history. This detailed 1995 book results from the invitation to foremost experts to give essays on aspects of virus biology. Initial chapters cover impacts of viruses and their control. Further chapters detail genetic variation of viruses and the molecular basis of interrelations with hosts. This leads to discussions of interactions with the host at the population level, and their molecular basis and evolution. Seventeen chapters follow, by specialists on particular groups of viruses describing their impact, genetic origins, sources of variation, population genetics and interactions with hosts. Practical virologists will find the chapters on phylogenetic analysis techniques very useful. The adaptive nature of viruses makes this work highly relevant to evolutionists.

Author : Scott C. Weaver,Mark Denison,Marilyn J. Roossinck,Marco Vignuzzi
Publisher : Caister Academic Press Limited
Page : 0 pages
File Size : 47,9 Mb
Release : 2016
Category : Medical
ISBN : 1910190233

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Virus Evolution by Scott C. Weaver,Mark Denison,Marilyn J. Roossinck,Marco Vignuzzi Pdf

The field of virus evolution has developed during the past three decades, from one considered by many to be esoteric and unimportant for human and agricultural health, to a major driver of our thinking about infectious diseases of plants and animals. The field has been spurred on during the past 30 years by emerging viral diseases such as HIV/AIDS, hantaviruses, SARS, MERS, and Ebola, along with discoveries of the quasispecies nature and potential for rapid evolution and diversification of RNA virus populations. Over time, the focus of research has expanded and developed to encompass a diverse mixture of approaches, from highly theoretical and mechanistic studies of the basic evolutionary mechanisms to detailed research on the molecular host range, as well as virulence changes responsible for emerging viral diseases. This timely book addresses a wide range of current questions and research approaches at the forefront of the field and highlights recent advances in the understanding of the history and mechanisms of virus evolution. Wherever possible, the book's contributors have integrated information from the study of plant, animal, and bacterial viruses. Every effort has been made to unify findings and to highlight the diversity in patterns and modes of virus evolution between systems in order to aid comparative analysis. The book will be essential reading for everyone working on virus evolution and emerging viral diseases. It is also recommended for anyone working in the area of viral pathogenesis. [Subject: Microbiology, Virology, Life Science]

Author : Stephen S. Morse
Publisher : Lippincott Williams & Wilkins
Page : 376 pages
File Size : 52,5 Mb
Release : 1994
Category : Medical
ISBN : UOM:39015026857246

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The Evolutionary Biology of Viruses by Stephen S. Morse Pdf

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 397 pages
File Size : 46,9 Mb
Release : 2016-10-21
Category : Medical
ISBN : 9780309377591

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Global Health Impacts of Vector-Borne Diseases by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Global Health,Forum on Microbial Threats Pdf

Pathogens transmitted among humans, animals, or plants by insects and arthropod vectors have been responsible for significant morbidity and mortality throughout recorded history. Such vector-borne diseases â€" including malaria, dengue, yellow fever, and plague â€" together accounted for more human disease and death in the 17th through early 20th centuries than all other causes combined. Over the past three decades, previously controlled vector-borne diseases have resurged or reemerged in new geographic locations, and several newly identified pathogens and vectors have triggered disease outbreaks in plants and animals, including humans. Domestic and international capabilities to detect, identify, and effectively respond to vector-borne diseases are limited. Few vaccines have been developed against vector-borne pathogens. At the same time, drug resistance has developed in vector-borne pathogens while their vectors are increasingly resistant to insecticide controls. Furthermore, the ranks of scientists trained to conduct research in key fields including medical entomology, vector ecology, and tropical medicine have dwindled, threatening prospects for addressing vector-borne diseases now and in the future. In June 2007, as these circumstances became alarmingly apparent, the Forum on Microbial Threats hosted a workshop to explore the dynamic relationships among host, pathogen(s), vector(s), and ecosystems that characterize vector-borne diseases. Revisiting this topic in September 2014, the Forum organized a workshop to examine trends and patterns in the incidence and prevalence of vector-borne diseases in an increasingly interconnected and ecologically disturbed world, as well as recent developments to meet these dynamic threats. Participants examined the emergence and global movement of vector-borne diseases, research priorities for understanding their biology and ecology, and global preparedness for and progress toward their prevention, control, and mitigation. This report summarizes the presentations and discussions from the workshop.

Author : Yechiel Becker,Gholamreza Darai
Publisher : Springer Science & Business Media
Page : 123 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461517078

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Molecular Evolution of Viruses — Past and Present by Yechiel Becker,Gholamreza Darai Pdf

The studies in this special issue of VIRUS GENES provide information on the mechanisms by which viruses have evolved together with their natural hosts by acquiring RNA and DNA molecules from the infected cells into their genomes. Part A is devoted to studies on virus genes that were acquired to evade the vertebrate host immune system. Part B deals with the acquisition of cellular and foreign virus genes by Herpes and Irido viruses. The studies presented in Part C describe the poxvirus genes that are homologues of cellular genes. Together, these studies provide an insight into the evolutionary processes that viruses have developed to control the metabolic machinery of the infected tissue cells, and to prevent the defense machinery of the infected host, e.g., the immune system, from recognizing the infecting virus. Such mechanisms may explain the pathogenicity and reflect the virulence of viruses. Molecular Evolution of Viruses - Past and Present: Evolution of Viruses by Acquisition of Cellular RNA and DNA was preceded by two VIRUS GENES special issues on the evolution of viruses (VIRUS GENES 11:2/3, 1996, and VIRUS GENES 16:1, 1998). The first special issue dealt with the evolution of retrons, retroelements, retroviruses and endogenous retroviruses and current evolution of viruses. The second special issue provided information on the evolution of human, marine algae and fungal viruses. These issues, together with the third special issue on virus evolution, provide an interesting insight into the evolution of DNA and RNA viruses.

Author : Anonim
Publisher : Elsevier
Page : 610 pages
File Size : 51,8 Mb
Release : 2003-10-02
Category : Science
ISBN : 9780080493770

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Virus Structure by Anonim Pdf

Virus Structure covers the full spectrum of modern structural virology. Its goal is to describe the means for defining moderate to high resolution structures and the basic principles that have emerged from these studies. Among the topics covered are Hybrid Vigor, Structural Folds of Viral Proteins, Virus Particle Dynamics, Viral Gemone Organization, Enveloped Viruses and Large Viruses. Covers viral assembly using heterologous expression systems and cell extracts Discusses molecular mechanisms in bacteriophage T7 procapsid assembly, maturation and DNA containment Includes information on structural studies on antibody/virus complexes

Author : Esteban Domingo
Publisher : Unknown
Page : 188 pages
File Size : 41,9 Mb
Release : 2001
Category : Medical
ISBN : 1587060108

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Quasispecies and RNA Virus Evolution by Esteban Domingo Pdf

Author : Daniele Focosi
Publisher : Springer Nature
Page : 140 pages
File Size : 54,6 Mb
Release : 2021-10-11
Category : Medical
ISBN : 9783030873240

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SARS-CoV-2 Spike Protein Convergent Evolution by Daniele Focosi Pdf

This book reviews the current knowledge of the globally circulating SARS-CoV-2 variants, highlights their distinct genetic characteristics and associated conformational changes in the viral spike protein, and profoundly discusses the mechanisms of convergent evolution that led to the rise of these mutated strains at different geographic regions during the Covid-19 pandemic. Furthermore, the book explores how these variants do and may impact the efficacy of established neutralizing antibody-based (nAb) vaccines and therapeutics by analysing latest in vivo and in vitro clinical data. Finally, the author discusses ways on how nAb Covid-19 treatment derived immune escape of SARS-CoV-2 could be minimized in the future.

Author : Esteban Domingo
Publisher : Academic Press
Page : 428 pages
File Size : 48,5 Mb
Release : 2015-09-25
Category : Science
ISBN : 9780128009949

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Virus as Populations by Esteban Domingo Pdf

Virus as Populations: Composition, Complexity, Dynamics, and Biological Implications explains fundamental concepts that arise from regarding viruses as complex populations when replicating in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, probability to be transmitted or response to treatment, depend on virus population numbers and in the variations of such population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, new antiviral strategies such as lethal mutagenesis, and extensions of population heterogeneity to nonviral systems are included. These main concepts of the book are framed in recent observations on general virus diversity derived from metagenomic studies, and current views on the origin of viruses and the role of viruses in the evolution of the biosphere. Features current views on the key steps in the origin of life and origins of viruses Includes examples relating ancestral features of viruses with their current adaptive capacity Explains complex phenomena in an organized and coherent fashion that is easy to comprehend and enjoyable to read Considers quasispecies as a framework to understand virus adaptability and disease processes