Viruses And Man A History Of Interactions

Author : Milton W. Taylor
Publisher : Springer
Page : 430 pages
File Size : 46,9 Mb
Release : 2014-07-21
Category : Medical
ISBN : 9783319077581

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Viruses and Man: A History of Interactions by Milton W. Taylor Pdf

Milton Taylor, Indiana University, offers an easy-to-read and fascinating text describing the impact of viruses on human society. The book starts with an analysis of the profound effect that viral epidemics had on world history resulting in demographic upheavals by destroying total populations. It also provides a brief history of virology and immunology. Furthermore, the use of viruses for the treatment of cancer (viral oncolysis or virotherapy) and bacterial diseases (phage therapy) and as vectors in gene therapy is discussed in detail. Several chapters focus on viral diseases such as smallpox, influenza, polio, hepatitis and their control, as well as on HIV and AIDS and on some emerging viruses with an interesting story attached to their discovery or vaccine development. The book closes with a chapter on biological weapons. It will serve as an invaluable source of information for beginners in the field of virology as well as for experienced virologists, other academics, students, and readers without prior knowledge of virology or molecular biology.

Author : Esteban Domingo,Colin R. Parrish,John J. Holland
Publisher : Elsevier
Page : 573 pages
File Size : 47,7 Mb
Release : 2008-06-23
Category : Science
ISBN : 9780080564968

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Origin and Evolution of Viruses by Esteban Domingo,Colin R. Parrish,John J. Holland Pdf

New viral diseases are emerging continuously. Viruses adapt to new environments at astounding rates. Genetic variability of viruses jeopardizes vaccine efficacy. For many viruses mutants resistant to antiviral agents or host immune responses arise readily, for example, with HIV and influenza. These variations are all of utmost importance for human and animal health as they have prevented us from controlling these epidemic pathogens. This book focuses on the mechanisms that viruses use to evolve, survive and cause disease in their hosts. Covering human, animal, plant and bacterial viruses, it provides both the basic foundations for the evolutionary dynamics of viruses and specific examples of emerging diseases. NEW - methods to establish relationships among viruses and the mechanisms that affect virus evolution UNIQUE - combines theoretical concepts in evolution with detailed analyses of the evolution of important virus groups SPECIFIC - Bacterial, plant, animal and human viruses are compared regarding their interation with their hosts

Author : Michel Tibayrenc
Publisher : Elsevier
Page : 773 pages
File Size : 55,6 Mb
Release : 2010-12-17
Category : Medical
ISBN : 9780123848901

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Genetics and Evolution of Infectious Diseases by Michel Tibayrenc Pdf

Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field

Author : Karl Maramorosch,Edouard Kurstak
Publisher : Academic Press
Page : 600 pages
File Size : 52,8 Mb
Release : 2014-06-28
Category : Science
ISBN : 9781483269696

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Comparative Virology by Karl Maramorosch,Edouard Kurstak Pdf

Comparative Virology provides an integrated comparison of viruses, based on their chemical and morphological characteristics. These descriptions will not only give the reader a background but also a detailed analysis of the various groups. In some instances the groups are still host related, as in the case of bacteriophages and polyhedral insect viruses. In others, for instance in pox viruses, the group comprises viruses of vertebrates and invertebrates. The hosts of the bacilliform Rhabdovirales range from man and other warm-blooded vertebrates through invertebrate animals to plants. A special chapter is devoted to viruses devoid of protein—a group that is of great interest and that has only recently been recognized. Since there is historical and practical interest in écologie groupings, such as arboviruses and oncogenic viruses, chapters on such groups have also been included. The book opens with a discussion on the classification of viruses. Chapters dealing with DNA viruses and RNA viruses follow, and the ecologically and disease-oriented groups complete the volume. It is hoped that ""Comparative Virology"" will help bring unity to the science of virology through the comparative approach that is not dependent on virus-host interactions. The combined efforts of eminent contributors to discuss and evaluate new information will hopefully benefit all who are interested in virology

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Policy and Global Affairs,Committee on Science, Technology, and Law,Division on Earth and Life Studies,Board on Life Sciences
Publisher : National Academies Press
Page : 140 pages
File Size : 45,5 Mb
Release : 2015-04-13
Category : Science
ISBN : 9780309367868

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Potential Risks and Benefits of Gain-of-Function Research by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Policy and Global Affairs,Committee on Science, Technology, and Law,Division on Earth and Life Studies,Board on Life Sciences Pdf

On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.

Author : R. Ahmed,Irvin Chen
Publisher : Wiley-Blackwell
Page : 754 pages
File Size : 55,9 Mb
Release : 1999
Category : Medical
ISBN : UOM:39015041993448

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Persistent Viral Infections by R. Ahmed,Irvin Chen Pdf

Persistent Viral Infections Edited by Rafi Ahmed Emory Vaccine Center, Atlanta, USA and Irvin S. Y. Chen UCLA School of Medicine, Los Angeles, USA During the past decade much of our attention has focused on diseases associated with viral persistence. Major breakthroughs in immunology, and the advent of molecular approaches to study pathogenesis have increased our understanding of the complex virus-host interactions that occur during viral persistence. Persistent Viral Infections focuses on: * The pathogenesis and immunology of chronic infections * Animal models that provide, or have the potential to provide, major insights This volume will be essential reading for virologists, immunologists, oncologists and neurologists.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 40,6 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 431 pages
File Size : 40,5 Mb
Release : 2005-04-09
Category : Medical
ISBN : 9780309095044

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The Threat of Pandemic Influenza by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Public health officials and organizations around the world remain on high alert because of increasing concerns about the prospect of an influenza pandemic, which many experts believe to be inevitable. Moreover, recent problems with the availability and strain-specificity of vaccine for annual flu epidemics in some countries and the rise of pandemic strains of avian flu in disparate geographic regions have alarmed experts about the world's ability to prevent or contain a human pandemic. The workshop summary, The Threat of Pandemic Influenza: Are We Ready? addresses these urgent concerns. The report describes what steps the United States and other countries have taken thus far to prepare for the next outbreak of "killer flu." It also looks at gaps in readiness, including hospitals' inability to absorb a surge of patients and many nations' incapacity to monitor and detect flu outbreaks. The report points to the need for international agreements to share flu vaccine and antiviral stockpiles to ensure that the 88 percent of nations that cannot manufacture or stockpile these products have access to them. It chronicles the toll of the H5N1 strain of avian flu currently circulating among poultry in many parts of Asia, which now accounts for the culling of millions of birds and the death of at least 50 persons. And it compares the costs of preparations with the costs of illness and death that could arise during an outbreak.

Author : Ronald Eccles,Olaf Weber
Publisher : Springer Science & Business Media
Page : 358 pages
File Size : 44,6 Mb
Release : 2009-11-16
Category : Medical
ISBN : 9783764399122

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Common Cold by Ronald Eccles,Olaf Weber Pdf

The common cold is unlike any other human disease because of two f- tors: firstly, it is arguably the most common human disease and, secondly, it is one of the most complex diseases because of the number of viruses that cause the familiar syndrome of sneezing, sore throat, runny nose and nasal congestion. These two factors have made a ‘cure’ for the common cold one of the most difficult scientific and clinical endeavours (a topic often d- cussed in the popular media, where comparisons are made with the ease of putting a man on the moon). The present book brings together a wide range of experts from epidemiologists to virologists and pharmacologists to look at recent advances in our knowledge of the common cold. In some respects the book is unique, as it focuses on the common cold, a syndrome so familiar to the layperson but one that receives little attention from the scientist and clinician. The common cold can be viewed from many different aspects as illustrated in Figure 1. The core knowledge for understanding the common cold must first come from virology and this is discussed in several chapters of the book. There have been major advances in this field because of the use of new methods of detecting viruses such as polymerase chain reaction techniques that have greatly aided our understanding of the epidemiology of viruses associated with common cold.

Author : Arno Karlen
Publisher : Simon and Schuster
Page : 276 pages
File Size : 54,9 Mb
Release : 1996-05-22
Category : Science
ISBN : 9780684822709

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Man and Microbes by Arno Karlen Pdf

A noted medical historian places recent outbreaks of deadly diseases in historical perspective, with accounts of other alarming and recurring diseases throughout history and of the ways in which humans have adapted. Reprint. 17,500 first printing.

Author : Pooja Jain,Lishomwa C. Ndhlovu
Publisher : Springer Nature
Page : 413 pages
File Size : 46,8 Mb
Release : 2020-08-11
Category : Medical
ISBN : 9783030339463

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Advanced Concepts in Human Immunology: Prospects for Disease Control by Pooja Jain,Lishomwa C. Ndhlovu Pdf

This book highlights information derived primarily from clinical samples, with particular reference to theoretical and scientific aspects of the human immune system. This text will focus on topics that range from host-pathogen interactions in infectious disease to host immune response in cancer, allergic diseases, neuroinflammatory diseases, and autoimmune disorders. The reader will also have a well-rounded understanding of the behavior of the immune system with particular emphasis on the role of immunoproteomics in immunotherapy, neuroprotective immunity for neurodegenerative and neuroinfectious disease, leukemia-associated dendritic cell induction of adaptive immunity dysregulation, and the role of immune checkpoint inhibitors in cancer, infection, as well as neuroinflammation. Taken together, the contents of this book are intended for both clinicians and researchers in academia and industry.

Author : Dorothy Crawford
Publisher : OUP Oxford
Page : 295 pages
File Size : 41,9 Mb
Release : 2002-03-21
Category : Medical
ISBN : 9780191622489

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The Invisible Enemy by Dorothy Crawford Pdf

Viruses are disarmingly small and simple. None the less, the smallpox virus killed over 300 million people in the 20th century prior to its eradication in 1980. The AIDS virus, HIV, is now the single most common cause of death in Africa. In recent years, the outbreaks of several lethal viruses such as Ebola and hanta virus have caused great public concern. In her fascinating and vividly written book, Dorothy Crawford describes all aspects of the natural history of these deadly parasites, explaining how they differ from other microorganisms. She looks at the havoc viruses have caused in the past, where they have come from, and the detective work involved in uncovering them. Finally, she considers whether a new virus could potentially wipe out the human race. This is an informative and highly readable book, which will be read by all those seeking a deeper understanding of these minute but remarkably efficient killers.

Author : Peter M. Howley,David M. Knipe
Publisher : Lippincott Williams & Wilkins
Page : 2597 pages
File Size : 52,7 Mb
Release : 2020-02-11
Category : Medical
ISBN : 9781975112554

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Fields Virology: Emerging Viruses by Peter M. Howley,David M. Knipe Pdf

Now in four convenient volumes, Field’s Virology remains the most authoritative reference in this fast-changing field, providing definitive coverage of virology, including virus biology as well as replication and medical aspects of specific virus families. This volume of Field’s Virology: Emerging Viruses, 7th Edition covers recent changes in emerging viruses, providing new or extensively revised chapters that reflect these advances in this dynamic field.

Author : Richard Preston
Publisher : Anchor
Page : 450 pages
File Size : 43,9 Mb
Release : 1995
Category : Health & Fitness
ISBN : 9780385479561

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The Hot Zone by Richard Preston Pdf

The virus kills nine out of ten of its victims. Its effects are so quick and so gruesome that even biohazard experts are terrified. It is airborne, it is extremely contagious, and it is about to burn through the suburbs of Washington, D.C. Is there any way to stop it? This doomsday scenario confronted a biohazard SWAT team struggling in secret to stop the outbreak of an exotic "hot" virus at an Army research facility outside Washington. "The Hot Zone" tells the dramatic story of their dangerous race against time, along with an alarming account of how previously unknown viruses that have lived undetected in the rain forest for eons are now entering human populations. From the airlocked confines of a biosafety level 4 military lab, to an airliner over Kenya carrying a passenger dissolving into a human virus bomb, to a deserted jungle cave alive with deadly virus, THE HOT ZONE is a non-fiction thriller like no other. "The Andromeda Strain" was fiction--- "this is real!"

Author : Luke S. P. Moore,James C. Hatcher
Publisher : Cambridge University Press
Page : 257 pages
File Size : 48,6 Mb
Release : 2019-12-05
Category : Medical
ISBN : 9781316609712

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Infectious Diseases, Microbiology and Virology by Luke S. P. Moore,James C. Hatcher Pdf

A key resource for FRCPath and MRCP trainees, mapped to the current curriculum, using over 300 exam-style Q&A.