A Control Theoretic Approach To Dynamic Optimization Of Metabolic Networks

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21st European Symposium on Computer Aided Process Engineering

Author : E. N. Pistikopoulos,Michael C. Georgiadis,Antonis C. Kokossis
Publisher : Elsevier
Page : 2087 pages
File Size : 54,6 Mb
Release : 2011-07-21
Category : Science
ISBN : 9780444538956

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21st European Symposium on Computer Aided Process Engineering by E. N. Pistikopoulos,Michael C. Georgiadis,Antonis C. Kokossis Pdf

The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, scientists, researchers, managers and students to present and discuss progress being made in the area of computer aided process engineering (CAPE). European industries large and small are bringing innovations into our lives, whether in the form of new technologies to address environmental problems, new products to make our homes more comfortable and energy efficient or new therapies to improve the health and well being of European citizens. Moreover, the European Industry needs to undertake research and technological initiatives in response to humanity's "Grand Challenges," described in the declaration of Lund, namely, Global Warming, Tightening Supplies of Energy, Water and Food, Ageing Societies, Public Health, Pandemics and Security. Thus, the Technical Theme of ESCAPE 21 will be "Process Systems Approaches for Addressing Grand Challenges in Energy, Environment, Health, Bioprocessing & Nanotechnologies."

2020 International Conference on Applications and Techniques in Cyber Intelligence

Author : Jemal H. Abawajy,Kim-Kwang Raymond Choo,Zheng Xu,Mohammed Atiquzzaman
Publisher : Springer Nature
Page : 1144 pages
File Size : 49,9 Mb
Release : 2020-08-12
Category : Computers
ISBN : 9783030539801

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2020 International Conference on Applications and Techniques in Cyber Intelligence by Jemal H. Abawajy,Kim-Kwang Raymond Choo,Zheng Xu,Mohammed Atiquzzaman Pdf

This book presents innovative ideas, cutting-edge findings, and novel techniques, methods, and applications in a broad range of cybersecurity and cyberthreat intelligence areas. As our society becomes smarter, there is a corresponding need to secure our cyberfuture. The book describes approaches and findings that are of interest to business professionals and governments seeking to secure our data and underpin infrastructures, as well as to individual users.

Encyclopedia of Theoretical Ecology

Author : Alan Hastings,Louis Gross
Publisher : Univ of California Press
Page : 848 pages
File Size : 50,7 Mb
Release : 2012-05-31
Category : Nature
ISBN : 9780520269651

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Encyclopedia of Theoretical Ecology by Alan Hastings,Louis Gross Pdf

"A bold and successful attempt to illustrate the theoretical foundations of all of the subdisciplines of ecology, including basic and applied, and extending through biophysical, population, community, and ecosystem ecology. Encyclopedia of Theoretical Ecology is a compendium of clear and concise essays by the intellectual leaders across this vast breadth of knowledge."--Harold Mooney, Stanford University "A remarkable and indispensable reference work that also is flexible enough to provide essential readings for a wide variety of courses. A masterful collection of authoritative papers that convey the rich and fundamental nature of modern theoretical ecology."--Simon A. Levin, Princeton University "Theoretical ecologists exercise their imaginations to make sense of the astounding complexity of both real and possible ecosystems. Imagining a real or possible topic left out of the Encyclopedia of Theoretical Ecology has proven just as challenging. This comprehensive compendium demonstrates that theoretical ecology has become a mature science, and the volume will serve as the foundation for future creativity in this area."--Fred Adler, University of Utah "The editors have assembled an outstanding group of contributors who are a great match for their topics. Sometimes the author is a key, authoritative figure in a field; and at other times, the author has enough distance to convey all sides of a subject. The next time you need to introduce ecology students to a theoretical topic, you'll be glad to have this encyclopedia on your bookshelf."--Stephen Ellner, Cornell University “Everything you wanted to know about theoretical ecology, and much that you didn’t know you needed to know but will now! Alan Hastings and Louis Gross have done us a great service by bringing together in very accessible form a huge amount of information about a broad, complicated, and expanding field.”--Daniel Simberloff, University of Tennessee, Knoxville

A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations

Author : Vishwesh V. Kulkarni,Guy-Bart Stan,Karthik Raman
Publisher : Springer
Page : 332 pages
File Size : 44,7 Mb
Release : 2014-07-03
Category : Medical
ISBN : 9789401790413

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A Systems Theoretic Approach to Systems and Synthetic Biology I: Models and System Characterizations by Vishwesh V. Kulkarni,Guy-Bart Stan,Karthik Raman Pdf

The complexity of biological systems has intrigued scientists from many disciplines and has given birth to the highly influential field of systems biology wherein a wide array of mathematical techniques, such as flux balance analysis, and technology platforms, such as next generation sequencing, is used to understand, elucidate, and predict the functions of complex biological systems. More recently, the field of synthetic biology, i.e., de novo engineering of biological systems, has emerged. Scientists from various fields are focusing on how to render this engineering process more predictable, reliable, scalable, affordable, and easy. Systems and control theory is a branch of engineering and applied sciences that rigorously deals with the complexities and uncertainties of interconnected systems with the objective of characterising fundamental systemic properties such as stability, robustness, communication capacity, and other performance metrics. Systems and control theory also strives to offer concepts and methods that facilitate the design of systems with rigorous guarantees on these properties. Over the last 100 years, it has made stellar theoretical and technological contributions in diverse fields such as aerospace, telecommunication, storage, automotive, power systems, and others. Can it have, or evolve to have, a similar impact in biology? The chapters in this book demonstrate that, indeed, systems and control theoretic concepts and techniques can have a significant impact in systems and synthetic biology. Volume I provides a panoramic view that illustrates the potential of such mathematical methods in systems and synthetic biology. Recent advances in systems and synthetic biology have clearly demonstrated the benefits of a rigorous and systematic approach rooted in the principles of systems and control theory - not only does it lead to exciting insights and discoveries but it also reduces the inordinately lengthy trial-and-error process of wet-lab experimentation, thereby facilitating significant savings in human and financial resources. In Volume I, some of the leading researchers in the field of systems and synthetic biology demonstrate how systems and control theoretic concepts and techniques can be useful, or should evolve to be useful, in order to understand how biological systems function. As the eminent computer scientist Donald Knuth put it, "biology easily has 500 years of exciting problems to work on". This edited book presents but a small fraction of those for the benefit of (1) systems and control theorists interested in molecular and cellular biology and (2) biologists interested in rigorous modelling, analysis and control of biological systems.

Biology and Control Theory: Current Challenges

Author : Isabelle Queinnec,Sophie Tarbouriech,Germain Garcia,Silviu-Iulian Niculescu
Publisher : Springer
Page : 342 pages
File Size : 51,6 Mb
Release : 2007-08-07
Category : Technology & Engineering
ISBN : 9783540719885

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Biology and Control Theory: Current Challenges by Isabelle Queinnec,Sophie Tarbouriech,Germain Garcia,Silviu-Iulian Niculescu Pdf

Creating some links between control feedback and biology modeling communities based on similarities in modeling, observing and perceiving alive structures, and analyzing interconnections between biological structures and subsystems was the main objective of this volume. In this context, biology systems need appropriate analysis tools due to their structure and hierarchy, complexity and environment interference, and we believe that these aspects may generate interesting research topics in control area. Indeed, several works, raising the potential impact of control developments to bring some beginning of answers in the context of biological systems, have been published in the recent years. The idea of this book was conceived in the context mentioned above with the objective to help in claiming many of the problems for control researchers, starting discussions and opening interactive debates between the control and biology communities, and, finally, to alert graduate students to the many interesting ideas at the frontier between control feedback theory and biology.

Pathway Analysis and Optimization in Metabolic Engineering

Author : Néstor V. Torres,Eberhard O. Voit
Publisher : Cambridge University Press
Page : 328 pages
File Size : 49,6 Mb
Release : 2002-12-19
Category : Science
ISBN : 1139437615

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Pathway Analysis and Optimization in Metabolic Engineering by Néstor V. Torres,Eberhard O. Voit Pdf

Facility in the targeted manipulation of the genetic and metabolic composition of organisms, combined with unprecedented computational power, is forging a niche for a new subspecialty of biotechnology called metabolic engineering. First published in 2002, this book introduces researchers and advanced students in biology and engineering to methods of optimizing biochemical systems of biotechnological relevance. It examines the development of strategies for manipulating metabolic pathways, demonstrates the need for effective systems models, and discusses their design and analysis, while placing special emphasis on optimization. The authors propose power-law models and methods of biochemical systems theory toward these ends. All concepts are derived from first principles, and the text is richly illustrated with numerous graphs and examples throughout. Special features include: nontechnical and technical introductions to models of biochemical systems; a review of basic methods of model design and analysis; concepts of optimization; and detailed case studies.

Advances in Systems Biology

Author : Igor I. Goryanin,Andrew B. Goryachev
Publisher : Springer Science & Business Media
Page : 679 pages
File Size : 40,8 Mb
Release : 2011-12-08
Category : Science
ISBN : 9781441972095

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Advances in Systems Biology by Igor I. Goryanin,Andrew B. Goryachev Pdf

The International Society for Systems Biology (ISSB) is a society aimed at advancing world-wide systems biology research by providing a forum for scientific discussions and various academic services. The ISSB helps coordinate researchers to form alliances for meeting the unique needs of multidisciplinary and international systems biology research. The annual International Conference on Systems Biology (ICSB) serves as the main meeting for the society and is one of the largest academic and commercial gatherings under the broad heading of ‘Systems Biology’.

Plant Metabolic Networks

Author : Jörg Schwender
Publisher : Springer Science & Business Media
Page : 342 pages
File Size : 47,5 Mb
Release : 2009-06-12
Category : Science
ISBN : 9780387787459

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Plant Metabolic Networks by Jörg Schwender Pdf

Plants are the basis for human nutrition and of increasing interest for the chemical industry as a source of chemical feed stocks. Fuels derived from plant biomass will increasingly replace fossil fuels in the future. In order to increase crop productivity, design new plant products, and create new energy crops, there is need for methods of qualitative and quantitative analysis of metabolism which are able to guide the rational re-design of metabolic networks. In this book, recent advances in qualitative and quantitative analysis of metabolism are summarized to give an overview of the current state of knowledge. Principles of the analysis of network structure, flux analysis, and kinetic modeling are described. Analytical methods necessary to produce the data needed for metabolic flux analysis and for kinetic modeling are described. The analysis of larger metabolic networks is only possible by using computer assistance. Therefore each chapter of the book shall also describe software available for this purpose.

11th International Conference on Practical Applications of Computational Biology & Bioinformatics

Author : Florentino Fdez-Riverola,Mohd Saberi Mohamad,Miguel Rocha,Juan F. De Paz,Tiago Pinto
Publisher : Springer
Page : 330 pages
File Size : 50,5 Mb
Release : 2017-06-19
Category : Technology & Engineering
ISBN : 9783319608167

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11th International Conference on Practical Applications of Computational Biology & Bioinformatics by Florentino Fdez-Riverola,Mohd Saberi Mohamad,Miguel Rocha,Juan F. De Paz,Tiago Pinto Pdf

Biological and biomedical research are increasingly driven by experimental techniques that challenge our ability to analyse, process and extract meaningful knowledge from the underlying data. The impressive capabilities of next-generation sequencing technologies, together with novel and constantly evolving, distinct types of omics data technologies, have created an increasingly complex set of challenges for the growing fields of Bioinformatics and Computational Biology. The analysis of the datasets produced and their integration call for new algorithms and approaches from fields such as Databases, Statistics, Data Mining, Machine Learning, Optimization, Computer Science and Artificial Intelligence. Clearly, Biology is more and more a science of information and requires tools from the computational sciences. In the last few years, we have seen the rise of a new generation of interdisciplinary scientists with a strong background in the biological and computational sciences. In this context, the interaction of researchers from different scientific fields is, more than ever, of foremost importance in boosting the research efforts in the field and contributing to the education of a new generation of Bioinformatics scientists. The PACBB’17 conference was intended to contribute to this effort and promote this fruitful interaction, with a technical program that included 39 papers spanning many different sub-fields in Bioinformatics and Computational Biology. Further, the conference promoted the interaction of scientists from diverse research groups and with a distinct background (computer scientists, mathematicians, biologists).

Models in Population, Community and Ecosystem Dynamics

Author : Mehdi Cherif,Jurek Kolasa,Rui-Wu Wang
Publisher : Frontiers Media SA
Page : 131 pages
File Size : 55,9 Mb
Release : 2024-04-01
Category : Science
ISBN : 9782832547199

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Models in Population, Community and Ecosystem Dynamics by Mehdi Cherif,Jurek Kolasa,Rui-Wu Wang Pdf

Foundations of Theoretical Approaches in Systems Biology

Author : Alberto Marin-Sanguino,Julio Vera,Rui Alves
Publisher : Frontiers Media SA
Page : 216 pages
File Size : 48,5 Mb
Release : 2019-01-11
Category : Electronic
ISBN : 9782889456833

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Foundations of Theoretical Approaches in Systems Biology by Alberto Marin-Sanguino,Julio Vera,Rui Alves Pdf

If biology in the 20th century was characterized by an explosion of new technologies and experimental methods, that of the 21st has seen an equally exuberant proliferation of mathematical and computational methods that attempt to systematize and explain the abundance of available data. As we live through the consolidation of a new paradigm where experimental data goes hand in hand with computational analysis, we contemplate the challenge of fusing these two aspects of the new biology into a consistent theoretical framework. Whether systems biology will survive as a field or be washed away by the tides of future fads will ultimately depend on its success to achieve this type of synthesis. The famous quote attributed to Kurt Lewin comes to mind: "there is nothing more practical than a good theory". This book presents a wide assortment of articles on systems biology in an attempt to capture the variety of current methods in systems biology and show how they can help to find answers to the challenges of modern biology.

Complexity Science: An Introduction

Author : Peletier Mark A,Van Santen Rutger A,Steur Erik
Publisher : World Scientific
Page : 428 pages
File Size : 50,9 Mb
Release : 2019-03-20
Category : Science
ISBN : 9789813239616

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Complexity Science: An Introduction by Peletier Mark A,Van Santen Rutger A,Steur Erik Pdf

This book on complexity science comprises a collection of chapters on methods and principles from a wide variety of disciplinary fields — from physics and chemistry to biology and the social sciences.In this two-part volume, the first part is a collection of chapters introducing different aspects in a coherent fashion, and providing a common basis and the founding principles of the different complexity science approaches; the next provides deeper discussions of the different methods of use in complexity science, with interesting illustrative applications.The fundamental topics deal with self-organization, pattern formation, forecasting uncertainties, synchronization and revolutionary change, self-adapting and self-correcting systems, and complex networks. Examples are taken from biology, chemistry, engineering, epidemiology, robotics, economics, sociology, and neurology.

Systems Biology

Author : Edda Klipp,Wolfram Liebermeister,Christoph Wierling,Axel Kowald
Publisher : John Wiley & Sons
Page : 504 pages
File Size : 51,9 Mb
Release : 2016-03-28
Category : Medical
ISBN : 9783527675661

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Systems Biology by Edda Klipp,Wolfram Liebermeister,Christoph Wierling,Axel Kowald Pdf

This advanced textbook is tailored for an introductory course in Systems Biology and is well-suited for biologists as well as engineers and computer scientists. It comes with student-friendly reading lists and a companion website featuring a short exam prep version of the book and educational modeling programs. The text is written in an easily accessible style and includes numerous worked examples and study questions in each chapter. For this edition, a section on medical systems biology has been included.

Springer Handbook of Automation

Author : Shimon Y. Nof
Publisher : Springer Science & Business Media
Page : 1841 pages
File Size : 48,5 Mb
Release : 2009-07-16
Category : Technology & Engineering
ISBN : 9783540788317

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Springer Handbook of Automation by Shimon Y. Nof Pdf

This handbook incorporates new developments in automation. It also presents a widespread and well-structured conglomeration of new emerging application areas, such as medical systems and health, transportation, security and maintenance, service, construction and retail as well as production or logistics. The handbook is not only an ideal resource for automation experts but also for people new to this expanding field.