A Guide To Biotechnology Tools In The Post Genomic Era

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A Guide to Biotechnology Tools in the Post Genomic Era

Gary Hardiman,Richard Lin

Author : Gary Hardiman,Richard Lin
Publisher : Unknown
Page : 0 pages
File Size : 49,9 Mb
Release : 2005-08
Category : Science
ISBN : 096640274X

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A Guide to Biotechnology Tools in the Post Genomic Era by Gary Hardiman,Richard Lin Pdf

An introduction to gene cloning, this analysis examines the current state of biotechnology. Exploring cutting-edge research methods for the analysis of gene expression, this book discusses the bioinformatics-based approach to uncovering novel genes from the finished human genome sequencing project also reviews how model organisms can be a platform for investigating biology and enabling therapeutic target discovery, and provides case studies for how genomics technologies are applied in specific areas of drug development.

Analysis of Genes and Genomes

Richard J. Reece

Author : Richard J. Reece
Publisher : John Wiley & Sons Incorporated
Page : 520 pages
File Size : 53,6 Mb
Release : 2020-06-12
Category : Medical
ISBN : 0470777818

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Analysis of Genes and Genomes by Richard J. Reece Pdf

All aspects of genetic engineering in the post-genomic era are covered, beginning with the basics of DNA structure and DNA metabolism. Strong emphasis is placed on the latest, post genomic technologies including DNA macro and microarrays, genome-wide two hybrid analysis, proteomics and bioinformatics. An example driven past-to-present approach to allow the experiments of today to be placed in an historical context Associated website including updates, additional content and illusions

Genomic and Proteomic Techniques

Ranil S. Dassanayake,Y. I. N. Silva Gunawardene

Author : Ranil S. Dassanayake,Y. I. N. Silva Gunawardene
Publisher : Alpha Science International, Limited
Page : 0 pages
File Size : 40,6 Mb
Release : 2011
Category : Science
ISBN : 1842656600

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Genomic and Proteomic Techniques by Ranil S. Dassanayake,Y. I. N. Silva Gunawardene Pdf

Describes the high throughput sophisticated computational tools and experimental techniques used in post genomic analyses to harness the genomic information to make novel biological discoveries. Beginning with a chapter on bioinformatics that introduces readers to Word Wide Web based servers and software programs that are widely used for mining genomic information it moves on to a miniaturized high throughput technique, DNA microarrays, tailored for studying genome-scale genotyping and gene-expression profiling. An overview of another high throughput proteomic technique; two-dimensional polyacrylamide gel electrophoresis used in proteome separation and mass spectrometry and protein sequencing related techniques used for characterization and identification of proteins is followed by a description of yet another miniaturized high throughput proteomic technique, Protein Microarrays, developed to overcome the limitations associated with DNA microarray and to provide direct information about protein quantity, interactions, functions etc. Knowledge-based theoretical three-dimensional protein structure modeling approach; homology modeling as a realistic method to minimize the ever widening gap between known protein coding sequences and known protein structures and fully automated protein modeling software and servers implemented in protein structure modeling in the post genomic era are also discussed.

Capitalizing on New Needs and New Opportunities

National Research Council,Policy and Global Affairs,Board on Science, Technology, and Economic Policy

Author : National Research Council,Policy and Global Affairs,Board on Science, Technology, and Economic Policy
Publisher : National Academies Press
Page : 354 pages
File Size : 41,8 Mb
Release : 2001-01-11
Category : Political Science
ISBN : 9780309170024

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Capitalizing on New Needs and New Opportunities by National Research Council,Policy and Global Affairs,Board on Science, Technology, and Economic Policy Pdf

This report addresses a topic of recognized policy concern. To capture the benefits of substantial U.S. investments in biomedical R&D, parallel investments in a wide range of seemingly unrelated disciplines are also required. This report summarizes a major conference that reviewed our nation's R&D support for biotechnology and information technologies. The volume includes newly commissioned research and makes recommendations and findings concerning the important relationship between information technologies and biotechnology. It emphasizes the fall off in R&D investments needed to sustain the growth of the U.S. economy and to capitalize on the growing investment in biomedicine. It also encourages greater support for inter-disciplinary training to support new areas such as bioinformatics and urges more emphasis on and support for multi-disciplinary research centers.

Preparing for Future Products of Biotechnology

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Board on Agriculture and Natural Resources,Board on Life Sciences,Committee on Future Biotechnology Products and Opportunities to Enhance Capabilities of the Biotechnology Regulatory System

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Board on Agriculture and Natural Resources,Board on Life Sciences,Committee on Future Biotechnology Products and Opportunities to Enhance Capabilities of the Biotechnology Regulatory System
Publisher : National Academies Press
Page : 231 pages
File Size : 47,6 Mb
Release : 2017-07-28
Category : Science
ISBN : 9780309452052

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Preparing for Future Products of Biotechnology by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Board on Agriculture and Natural Resources,Board on Life Sciences,Committee on Future Biotechnology Products and Opportunities to Enhance Capabilities of the Biotechnology Regulatory System Pdf

Between 1973 and 2016, the ways to manipulate DNA to endow new characteristics in an organism (that is, biotechnology) have advanced, enabling the development of products that were not previously possible. What will the likely future products of biotechnology be over the next 5â€"10 years? What scientific capabilities, tools, and/or expertise may be needed by the regulatory agencies to ensure they make efficient and sound evaluations of the likely future products of biotechnology? Preparing for Future Products of Biotechnology analyzes the future landscape of biotechnology products and seeks to inform forthcoming policy making. This report identifies potential new risks and frameworks for risk assessment and areas in which the risks or lack of risks relating to the products of biotechnology are well understood.

Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era

Christine Foyer,Hanma Zhang

Author : Christine Foyer,Hanma Zhang
Publisher : John Wiley & Sons
Page : 326 pages
File Size : 47,5 Mb
Release : 2011-06-09
Category : Science
ISBN : 9781444347654

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Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era by Christine Foyer,Hanma Zhang Pdf

The field of plant nitrogen metabolism continues to be a compelling focus for basic research activities because there is a strong demand for immediate solutions, particularly in key areas, such as improving plant nitrogen use efficiency, which are crucial to future agricultural sustainability and the future economic success of agriculture. The 13 reviews which comprise this excellent and carefully edited new volume bring together the expertise and enthusiasm of an international team of leading researchers. Topics covered include nitrogen sensing and signalling, uptake and membrane systems, nitric oxide, primary nitrogen assimilation and C/N balance and interactions, and regulation of root and plant architecture. Together, these reviews provide an insight into how plants sense, uptake and assimilate nitrogen into the organic compounds required for growth, co-ordinate nitrogen and carbon metabolism and regulate growth and development according to nitrogen availability. The transcription factors that act to integrate environmental nutrient (nitrogen) signals to co-ordinate primary and secondary metabolism are discussed, together with new concepts of cross-talk, transport and signalling, and how such molecular networks influence nitrogen and carbon cycling processes in the environment. Annual Plant Reviews, Volume 42: Nitrogen Metabolism in Plants in the Post-genomic Era is an essential purchase for advanced students, researchers and professionals in plant sciences, biochemistry, physiology, molecular biology, genetics and agricultural sciences, working in the academic and industrial sectors. Libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves.

Reaping the Benefits of Genomic and Proteomic Research

National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation

Author : National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation
Publisher : National Academies Press
Page : 188 pages
File Size : 49,7 Mb
Release : 2006-03-09
Category : Science
ISBN : 9780309164887

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Reaping the Benefits of Genomic and Proteomic Research by National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation Pdf

The patenting and licensing of human genetic material and proteins represents an extension of intellectual property (IP) rights to naturally occurring biological material and scientific information, much of it well upstream of drugs and other disease therapies. This report concludes that IP restrictions rarely impose significant burdens on biomedical research, but there are reasons to be apprehensive about their future impact on scientific advances in this area. The report recommends 13 actions that policy-makers, courts, universities, and health and patent officials should take to prevent the increasingly complex web of IP protections from getting in the way of potential breakthroughs in genomic and proteomic research. It endorses the National Institutes of Health guidelines for technology licensing, data sharing, and research material exchanges and says that oversight of compliance should be strengthened. It recommends enactment of a statutory exception from infringement liability for research on a patented invention and raising the bar somewhat to qualify for a patent on upstream research discoveries in biotechnology. With respect to genetic diagnostic tests to detect patient mutations associated with certain diseases, the report urges patent holders to allow others to perform the tests for purposes of verifying the results.

Carotenoids: Biological Functions of Carotenoids and Apocarotenoids in Natural and Artificial Systems

Anonim

Author : Anonim
Publisher : Academic Press
Page : 566 pages
File Size : 45,9 Mb
Release : 2022-08-23
Category : Science
ISBN : 9780323913522

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Carotenoids: Biological Functions of Carotenoids and Apocarotenoids in Natural and Artificial Systems by Anonim Pdf

Carotenoids: Biological Functions of Carotenoids and Apocarotenoids in Natural and Artificial Systems, Volume 674 in the Methods in Enzymology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Ultrafast laser spectroscopic studies on carotenoids in solution and on those bound to photosynthetic pigment-protein complexes, Assessing photoprotective functions of carotenoids in photosynthetic systems of plants and green algae, Fluorescence of carotenoids: probing binding site interactions and conformational motion in carotenoproteins, Resonance Raman: A powerful tool to interrogate carotenoids in biological matrices, and much more. Other chapters in the book cover Engineering the carotenoid biosynthetic pathway to study the function of carotenoids in light-harvesting complexes, Carotenoids as proxies for variations in photosynthesis and phenology in response to environmental and climatic change, Apocarotenoid pigment biosynthesis in non-model plants, Apocarotenoid transport in plants, Screening for apocarotenoid plant growth regulators in Arabidopsis, Effects of herbivory on carotenoid biosynthesis and breakdown, Biosynthesis and action of apocarotenoid plant hormones, and much more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in Methods in Enzymology series Updated release includes the latest information on Carotenoids: Biological functions of carotenoids and apocarotenoids in natural and artificial systems

Review of the Department of Energy's Genomics: GTL Program

National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program
Publisher : National Academies Press
Page : 102 pages
File Size : 42,9 Mb
Release : 2006-04-19
Category : Science
ISBN : 9780309180719

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Review of the Department of Energy's Genomics: GTL Program by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program Pdf

The U.S. Department of Energy (DOE) promotes scientific and technological innovation to advance the national, economic, and energy security of the United States. Recognizing the potential of microorganisms to offer new energy alternatives and remediate environmental contamination, DOE initiated the Genomes to Life program, now called Genomics: GTL, in 2000. The program aims to develop a predictive understanding of microbial systems that can be used to engineer systems for bioenergy production and environmental remediation, and to understand carbon cycling and sequestration. This report provides an evaluation of the program and its infrastructure plan. Overall, the report finds that GTL's research has resulted in and promises to deliver many more scientific advancements that contribute to the achievement of DOE's goals. However, the DOE's current plan for building four independent facilities for protein production, molecular imaging, proteome analysis, and systems biology sequentially may not be the most cost-effective, efficient, and scientifically optimal way to provide this infrastructure. As an alternative, the report suggests constructing up to four institute-like facilities, each of which integrates the capabilities of all four of the originally planned facility types and focuses on one or two of DOE's mission goals. The alternative infrastructure plan could have an especially high ratio of scientific benefit to cost because the need for technology will be directly tied to the biology goals of the program.

Protecting Rice Grains in the Post-Genomic Era

Yulin Jia

Author : Yulin Jia
Publisher : BoD – Books on Demand
Page : 220 pages
File Size : 49,9 Mb
Release : 2019-10-02
Category : Technology & Engineering
ISBN : 9781789843873

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Protecting Rice Grains in the Post-Genomic Era by Yulin Jia Pdf

This book focuses on recent advances in genetic resources, host - pathogen interactions, assay methods, mechanisms of pathogenesis, and disease resistance. Environmentally benign crop protection methods for major rice diseases such as rice blast, sheath blight, bacterial blight, and newly emerged rice diseases such as false smut and bacterial panicle blight disease are included. The content also contains recent rice breeding methods for higher yield and improved disease resistance, rice processing, delicious rice recipes, and food safety. The book includes a comprehensive understanding of Bacillus thuringiensis toxin and its application for crop protection. Holistically, the book demonstrates successful applications of genomics, physiology, chemistry, genetics, pathology, soil science, and food technology to sustainably protect rice crops for global food safety.

The Date Palm Genome, Vol. 2

Jameel M. Al-Khayri,S. Mohan Jain,Dennis V. Johnson

Author : Jameel M. Al-Khayri,S. Mohan Jain,Dennis V. Johnson
Publisher : Springer Nature
Page : 264 pages
File Size : 48,9 Mb
Release : 2021-06-12
Category : Science
ISBN : 9783030737504

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The Date Palm Genome, Vol. 2 by Jameel M. Al-Khayri,S. Mohan Jain,Dennis V. Johnson Pdf

This book is the first comprehensive assemblage of contemporary knowledge relevant to genomics and other omics in date palm. Volume 2 consists of 11 chapters. Part I, Nutritional and Pharmaceuticals Properties, covers the utilization of date palm as an ingredient of various food products, a source of bioactive compounds and the production of nanomaterials. Part II, Omics Technologies, addresses omics resources, proteomics and metabolomics. Part III, Molecular Breeding and Genome Modification, focuses on genetic improvement technologies based on mutagenesis, quantitative traits loci and genome editing. Part IV, Genomics of Abiotic and Biotic Stress, covers metagenomics of beneficial microbes to enhance tolerance to abiotic stress and the various genomics advances as they apply to insect control. This volume represents the efforts of 34 international scientists from 12 countries and contains 65 figures and 19 tables to illustrate presented concepts. Volume 1 is published under the title: Phylogeny, Biodiversity and Mapping.

Genetically Engineered Crops

National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects
Publisher : National Academies Press
Page : 607 pages
File Size : 51,5 Mb
Release : 2017-01-28
Category : Science
ISBN : 9780309437387

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Genetically Engineered Crops by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects Pdf

Genetically engineered (GE) crops were first introduced commercially in the 1990s. After two decades of production, some groups and individuals remain critical of the technology based on their concerns about possible adverse effects on human health, the environment, and ethical considerations. At the same time, others are concerned that the technology is not reaching its potential to improve human health and the environment because of stringent regulations and reduced public funding to develop products offering more benefits to society. While the debate about these and other questions related to the genetic engineering techniques of the first 20 years goes on, emerging genetic-engineering technologies are adding new complexities to the conversation. Genetically Engineered Crops builds on previous related Academies reports published between 1987 and 2010 by undertaking a retrospective examination of the purported positive and adverse effects of GE crops and to anticipate what emerging genetic-engineering technologies hold for the future. This report indicates where there are uncertainties about the economic, agronomic, health, safety, or other impacts of GE crops and food, and makes recommendations to fill gaps in safety assessments, increase regulatory clarity, and improve innovations in and access to GE technology.

Handbook of Biomarkers and Precision Medicine

Claudio Carini,Mark Fidock,Alain van Gool

Author : Claudio Carini,Mark Fidock,Alain van Gool
Publisher : CRC Press
Page : 631 pages
File Size : 46,8 Mb
Release : 2019-04-16
Category : Mathematics
ISBN : 9780429576737

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Handbook of Biomarkers and Precision Medicine by Claudio Carini,Mark Fidock,Alain van Gool Pdf

"The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications, discussed by knowledgeable and experienced scientists, readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work." -Maria Freire, Foundation for the National Institutes of Health Handbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government, academia, teaching hospitals, biotechnology and pharmaceutical companies share best practices, examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists, students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features: Detailed insights into biomarker discovery, validation and diagnostic development with implementation strategies Lessons-learned from successful Precision Medicine case studies A variety of exciting and emerging biomarker technologies The next frontiers and future challenges of biomarkers in Precision Medicine Claudio Carini, Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU, USA and Asia. Currently, Dr. Carini is Honorary Faculty at Kings’s College School of Medicine, London, UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca, Cambridge, UK. Prof.dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school, Nijmegen, NL.

Postgenomics

Sarah S. Richardson,Hallam Stevens

Author : Sarah S. Richardson,Hallam Stevens
Publisher : Duke University Press
Page : 304 pages
File Size : 44,7 Mb
Release : 2015-04-15
Category : Science
ISBN : 9780822375449

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Postgenomics by Sarah S. Richardson,Hallam Stevens Pdf

Ten years after the Human Genome Project’s completion the life sciences stand in a moment of uncertainty, transition, and contestation. The postgenomic era has seen rapid shifts in research methodology, funding, scientific labor, and disciplinary structures. Postgenomics is transforming our understanding of disease and health, our environment, and the categories of race, class, and gender. At the same time, the gene retains its centrality and power in biological and popular discourse. The contributors to Postgenomics analyze these ruptures and continuities and place them in historical, social, and political context. Postgenomics, they argue, forces a rethinking of the genome itself, and opens new territory for conversations between the social sciences, humanities, and life sciences. Contributors. Russ Altman, Rachel A. Ankeny, Catherine Bliss, John Dupré, Michael Fortun, Evelyn Fox Keller, Sabina Leonelli, Adrian Mackenzie, Margot Moinester, Aaron Panofsky, Sarah S. Richardson, Sara Shostak, Hallam Stevens

Encyclopedia of Bioinformatics and Computational Biology

Anonim

Author : Anonim
Publisher : Elsevier
Page : 3421 pages
File Size : 55,5 Mb
Release : 2018-08-21
Category : Medical
ISBN : 9780128114322

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Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

Encyclopedia of Bioinformatics and Computational Biology: ABC of Bioinformatics, Three Volume Set combines elements of computer science, information technology, mathematics, statistics and biotechnology, providing the methodology and in silico solutions to mine biological data and processes. The book covers Theory, Topics and Applications, with a special focus on Integrative –omics and Systems Biology. The theoretical, methodological underpinnings of BCB, including phylogeny are covered, as are more current areas of focus, such as translational bioinformatics, cheminformatics, and environmental informatics. Finally, Applications provide guidance for commonly asked questions. This major reference work spans basic and cutting-edge methodologies authored by leaders in the field, providing an invaluable resource for students, scientists, professionals in research institutes, and a broad swath of researchers in biotechnology and the biomedical and pharmaceutical industries. Brings together information from computer science, information technology, mathematics, statistics and biotechnology Written and reviewed by leading experts in the field, providing a unique and authoritative resource Focuses on the main theoretical and methodological concepts before expanding on specific topics and applications Includes interactive images, multimedia tools and crosslinking to further resources and databases

A Guide To Biotechnology Tools In The Post Genomic Era

A Guide to Biotechnology Tools in the Post Genomic Era by Gary Hardiman,Richard Lin Pdf

Analysis of Genes and Genomes by Richard J. Reece Pdf

Genomic and Proteomic Techniques by Ranil S. Dassanayake,Y. I. N. Silva Gunawardene Pdf

Capitalizing on New Needs and New Opportunities by National Research Council,Policy and Global Affairs,Board on Science, Technology, and Economic Policy Pdf

Annual Plant Reviews, Nitrogen Metabolism in Plants in the Post-genomic Era by Christine Foyer,Hanma Zhang Pdf

Reaping the Benefits of Genomic and Proteomic Research by National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation Pdf

Carotenoids: Biological Functions of Carotenoids and Apocarotenoids in Natural and Artificial Systems by Anonim Pdf

Review of the Department of Energy's Genomics: GTL Program by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Review of the Department of Energy's Genomics: GTL Program Pdf

Protecting Rice Grains in the Post-Genomic Era by Yulin Jia Pdf

The Date Palm Genome, Vol. 2 by Jameel M. Al-Khayri,S. Mohan Jain,Dennis V. Johnson Pdf

Genetically Engineered Crops by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Agriculture and Natural Resources,Committee on Genetically Engineered Crops: Past Experience and Future Prospects Pdf

Handbook of Biomarkers and Precision Medicine by Claudio Carini,Mark Fidock,Alain van Gool Pdf

Postgenomics by Sarah S. Richardson,Hallam Stevens Pdf

Encyclopedia of Bioinformatics and Computational Biology by Anonim Pdf

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