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Author : Kenneth C. Holmes
Publisher : Cambridge University Press
Page : 381 pages
File Size : 50,8 Mb
Release : 2017-02-09
Category : Science
ISBN : 9781107147379
The life and work of Aaron Klug, Nobel prize winner and one of the pioneers of structural molecular biology.
Author : John Meurig Thomas
Publisher : Oxford University Press
Page : 320 pages
File Size : 49,5 Mb
Release : 2020-02-28
Category : Science
ISBN : 9780192596710
Architects of Structural Biology is an amalgam of memoirs, biography, and intellectual history of the personalities and single-minded devotion of four scientists who are among the greatest in modern times. These three chemists and one physicist, all Nobel laureates, played a pivotal role in the creation of a new and pervasive branch of biology. This led in turn to major developments in medicine and to the treatment of diseases as a result of advances made in arguably one of the greatest centres of scientific research ever: the Laboratory of Molecular Biology in Cambridge, which they helped to establish. Their work and that of their predecessors at the Royal Institution in London reflects the broader cultural, scientific and educational strength of the UK from the early 19th century onwards. The book also illustrates the nurturing of academic life in the collegiate system, exemplified by the activities of, and cross-fertilization within, a small Cambridge college.
Author : Joachim Frank
Publisher : CRC Press
Page : 553 pages
File Size : 54,5 Mb
Release : 2023-10-06
Category : Science
ISBN : 9781000989441
Cryo-EM, as it is currently practiced in many laboratories, is limited to the visualization of molecules that are in thermal equilibrium at the time before freezing. A further limitation is that the existing software does not fully exploit the information that is contained in the images of large ensembles of molecules in thermal equilibrium. This book is a collection of recent articles by the author, reprinted with introductions, and they mainly describe two novel methods in cryo-EM, one computational and the other experimental that requires the use of a microfluidic device. Both methods have the capacity to shed light on the dynamic behavior of biomolecules. Combined, they greatly expand the range of applications of cryo-EM. The book describes a successful approach in which, based on cryo-EM data, all states visited by the molecule in thermal equilibrium are mapped by manifold embedding—a method of geometric machine learning—and the energy landscape of the molecule is derived. It also discusses methods and biological results of time-resolved cryo-EM, following a reaction in a non-equilibrium system over a short period of time and resulting in the capture of short-lived states that have been inaccessible by standard methods of cryo-EM.
Author : Paul M. Wassarman
Publisher : Oxford University Press, USA
Page : 369 pages
File Size : 40,9 Mb
Release : 2020
Category : Science
ISBN : 9780199732043
John C. Kendrew (1917-1997) was a pioneer in structural biology and a catalyst for the emergence of molecular biology in the second half of the twentieth century. He was the first person to determine the three-dimensional structure of a protein at atomic resolution and, for this, was awarded the Nobel Prize in Chemistry in 1962. Kendrew ultimately became an international organizer, administrator, and advocate for science, and his expansive legacy lives on today. In this book, Paul M. Wassarman, a postdoctoral fellow with Kendrew in the late 1960s, delves into Kendrew's personal and scientific life to uncover the background, traits, and experiences of the man responsible for so many achievements within science and beyond. Wassarman shares previously unpublished stories of Kendrew, including his vital role in the rise of molecular biology at three world-famous scientific institutions: the Cavendish Laboratory, Laboratory of Molecular Biology, and European Laboratory of Molecular Biology. Kendrew was an unwavering advocate for British and European science and one of the most gifted, influential, and accomplished figures in twentieth century science. A Place in History is a groundbreaking account of Kendrew's life that is perfect for anyone interested in learning about the person behind the many achievements.
Author : Soraya de Chadarevian
Publisher : Cambridge University Press
Page : 452 pages
File Size : 43,7 Mb
Release : 2002-05-30
Category : Medical
ISBN : 0521570786
An important study on the making of molecular biology and its cultural contexts.
Author : István Hargittai
Publisher : World Scientific
Page : 616 pages
File Size : 54,9 Mb
Release : 2002-03-15
Category : Science
ISBN : 9781783261390
This invaluable book contains 36 interviews, including 26 with Nobel laureates. It presents a cross-section of biomedical science, a field that has been dominant in science for the past half century. The in-depth conversations cover important research areas and discoveries, as well as the roads to these discoveries, including aspects of the scientists' work that never saw publication. They also bring out the humanness of the famous scientists — the reader learns about their backgrounds, aspirations, failings, and triumphs. The book is illustrated with snapshots of the conversations and photos provided by the interviewees. It is a follow-up to the critically acclaimed Candid Science: Conversations with Famous Chemists, by the same author. Contents: James D WatsonMaclyn McCartyJoshua LederbergArthur KornbergFrederick SangerFrançois JacobWalter Gilbert Benno Müller-HillMarshall W NirenbergDaniel NathansPaul Berg Kary B MullisGerald M EdelmanCésar MilsteinAlfred G GilmanGünter BlobelGeorge K RaddaMax F PerutzRichard HendersonAaron KlugJohn T FinchSidney AltmanEdward B LewisRita Levi-MontalciniLars ErnsterTorvard C LaurentGeorge KleinD Carleton GajdusekCharles WeissmannFrederick C RobbinsRosalyn YalowJames W BlackK Sune D BergströmJohn R VaneSalvador MoncadaRobert F Furchgott Readership: Biomedical scientists, biochemists, and general readers. Reviews:“The book is easy to read … Overall, they give an accurate flavor of biomedical research …”Choice “The present selection of interviews gives a cross section covering a broad range of topics, personalities, and circumstances of recording. I agree with Hargittai's evaluation and heartily recommend his book, suitable for both complete reading or browsing, to biomedical scientists, biochemists, chemists, historians of chemistry and or science, and general readers interested in the 'inside story' of the workings of 20th-century science.”The Chemical Educator “I heartily recommend this book, suitable for both complete reading or browsing, to biomedical scientists, biochemists, chemists, historians of chemistry and of science generally, and general readers interested in the 'inside story' of the workings of 20th-century science.”Chemical Heritage
Author : William Beinart,Saul Dubow
Publisher : Cambridge University Press
Page : 419 pages
File Size : 49,7 Mb
Release : 2021-05-20
Category : History
ISBN : 9781108837088
An innovative three hundred year exploration of the social and political contexts of science and the scientific imagination in South Africa.
Author : Aleksandr S. Spirin,Lidija P. Gavrilova
Publisher : Springer Science & Business Media
Page : 173 pages
File Size : 41,6 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642884467
This monograph is neither a historical outline of the development of the concepts of protein biosynthesis and the structure and functions of the ribosomes, nor an exhaustive survey of the literature on these questions. The monograph is based upon an analysis of the modern trends in this field. The purpose of the monograph was to formulate more or less generalized representations of the structure and" function of the ribosome, as we envision it at the present day. It may be that this attempt is premature for a number of reasons, and the concepts outlined here will very soon be revised. Nonetheless, despite this risk, we believe it to be advisable to undertake this attempt for the following reasons: firstly, the undertaken analysis could aid in the comprehension of the substantial mass of extremely scattered experimental data on the ribosomes presently available; secondly, in any event, even if most of the concepts outlined rapidly become obselete, they can still serve as a stimulus for a whole series of experiments; and thirdly, we hope that some of the concepts outlined will still remain essentially correct and relatively stable. In view of the aforementioned, we should make the following reservations. First of all, we made no attempt to cite all the literature on the problems discussed, but considered it sufficient to illustrate the various premises with one or several sample references.
Author : John Ringo
Publisher : Cambridge University Press
Page : 128 pages
File Size : 55,7 Mb
Release : 2004-03-25
Category : Science
ISBN : 9781316582893
Fundamental Genetics is a concise, non-traditional textbook that explains major topics of modern genetics in 42 mini-chapters. It is designed as a textbook for an introductory general genetics course and is also a useful reference or refresher on basic genetics for professionals and students in health sciences and biological sciences. It is organized for ease of learning, beginning with molecular structures and progressing through molecular processes to population genetics and evolution. Students will find the short, focused chapters approachable and more easily digested than the long, more complex chapters of traditional genetics textbooks. Each chapter focuses on one topic, so that teachers and students can readily tailor the book to their needs by choosing a subset of chapters. The book is extensively illustrated throughout with clear and uncluttered diagrams that are simple enough to be reproduced by students. This unique textbook provides a compact alternative for introductory genetics courses.
Author : Carolyn Hamilton,Verne Harris,Michèle Pickover,Graeme Reid,Razia Saleh,Jane Taylor
Publisher : Springer Science & Business Media
Page : 368 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Social Science
ISBN : 9789401005708
Refiguring the Archive at once expresses cutting-edge debates on `the archive' in South Africa and internationally, and pushes the boundaries of those debates. It brings together prominent thinkers from a range of disciplines, mainly South Africans but a number from other countries. Traditionally archives have been seen as preserving memory and as holding the past. The contributors to this book question this orthodoxy, unfolding the ways in which archives construct, sanctify, and bury pasts. In his contribution, Jacques Derrida (an instantly recognisable name in intellectual discourse worldwide) shows how remembering can never be separated from forgetting, and argues that the archive is about the future rather than the past. Collectively the contributors demonstrate the degree to which thinking about archives is embracing new realities and new possibilities. The book expresses a confidence in claiming for archival discourse previously unentered terrains. It serves as an early manual for a time that has already begun.
Author : Canada. Agriculture Canada. Research Branch
Publisher : Agriculture Canada
Page : 688 pages
File Size : 40,9 Mb
Release : 1993
Category : Science
ISBN : MINN:31951P00119896M
This publication is the result of a course on identification of Hymenoptera given three times since 1985 at the Centre for Land and Biological Resources Research. The considerable interest in these courses indicated the need for a comprehensive identification guide to all extant families of Hymenoptera. The main emphasis is on family identification using the keys, which are complemented by family sketches. The sketches include a taxonomic diagnosis to supplement the keys, a summary of the biology, the size and distribution, and important literature references.
Author : Panagiotis A. Tsonis
Publisher : Cambridge University Press
Page : 300 pages
File Size : 44,9 Mb
Release : 2003-01-13
Category : Science
ISBN : 0521804744
Table of contents
Author : Richard Anderson,Henry B. Lovejoy
Publisher : Rochester Studies in African H
Page : 482 pages
File Size : 53,9 Mb
Release : 2020
Category : History
ISBN : 9781580469692
"Interrogates the development of the world's first international courts of humanitarian justice and the subsequent "liberation" of nearly 200,000 Africans in the nineteenth century"--
Author : Murray Carlin
Publisher : Nairobi : Oxford University Press
Page : 80 pages
File Size : 55,5 Mb
Release : 1969
Category : English drama
ISBN : UCAL:$B146916
Author : Gary R. Mullen,Lance A. Durden
Publisher : Academic Press
Page : 646 pages
File Size : 49,9 Mb
Release : 2009-04-22
Category : Science
ISBN : 9780080919690
Medical and Veterinary Entomology, Second Edition, has been fully updated and revised to provide the latest information on developments in entomology relating to public health and veterinary importance. Each chapter is structured with the student in mind, organized by the major headings of Taxonomy, Morphology, Life History, Behavior and Ecology, Public Health and Veterinary Importance, and Prevention and Control. This second edition includes separate chapters devoted to each of the taxonomic groups of insects and arachnids of medical or veterinary concern, including spiders, scorpions, mites, and ticks. Internationally recognized editors Mullen and Durden include extensive coverage of both medical and veterinary entomological importance. This book is designed for teaching and research faculty in medical and veterinary schools that provide a course in vector borne diseases and medical entomology; parasitologists, entomologists, and government scientists responsible for oversight and monitoring of insect vector borne diseases; and medical and veterinary school libraries and libraries at institutions with strong programs in entomology. Follows in the tradition of Herm's Medical and Veterinary Entomology The latest information on developments in entomology relating to public health and veterinary importance Two separate indexes for enhanced searchability: Taxonomic and Subject New to this edition: Three new chapters Morphological Adaptations of Parasitic Arthropods Forensic Entomology Molecular Tools in Medical and Veterinary Entomology 1700 word glossary Appendix of Arthropod-Related Viruses of Medical-Veterinary Importance Numerous new full-color images, illustrations and maps throughout