Advanced Skin Cancer

Author : Debjani Sahni,Bilal Fawaz,Adam Lerner
Publisher : CRC Press
Page : 290 pages
File Size : 40,5 Mb
Release : 2022-04-28
Category : Medical
ISBN : 9780429648984

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Advanced Skin Cancer by Debjani Sahni,Bilal Fawaz,Adam Lerner Pdf

Advanced skin cancer is one that has already metastasized beyond its primary origin, or one that has invaded underlying tissues such that surgical resection either is technically impossible or would lead to an unacceptable functional or cosmetic outcome. These skin cancers present a complex problem that requires the input of multiple specialties to delineate the best management plan. National guidelines utilize the best available data to guide management decisions. However, there is considerable leeway within the guidelines, enabling the ultimate care decision to be molded to best fit each individual patient. This book aims to provide instructional examples of patient cases where the input of the multidisciplinary team is critical in providing the most suitable care plan for the patient. CONTENTS: Melanoma * Squamous Cell Carcinoma * Basal Cell Carcinoma * Cutaneous Lymphoma * Kaposi’s Sarcoma * Dermatofibrosarcoma Protuberans * Merkel Cell Carcinoma * Rare Cancer Presentations

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 41,7 Mb
Release : 2024-07-02
Category : Electronic
ISBN : OCLC:1125727614

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Cutaneous Melanoma by Anonim Pdf

Author : U.s. Department of Health and Human Services,Office of the Surgeon General
Publisher : Createspace Independent Publishing Platform
Page : 112 pages
File Size : 43,8 Mb
Release : 2014-10-21
Category : Medical
ISBN : 1502903857

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The Surgeon General's Call to Action to Prevent Skin Cancer by U.s. Department of Health and Human Services,Office of the Surgeon General Pdf

Skin cancer is the most commonly diagnosed cancer in the United States, yet most cases are preventable. Every year in the United States, nearly 5 million people are treated for skin cancer, at an estimated cost of $8.1 billion. Melanoma, the most deadly form of skin cancer, causes nearly 9,000 deaths each year. Despite recent efforts to address risk factors, skin cancer rates continue to rise. While those with lighter skin are more susceptible, anyone can get skin cancer—and it can be serious, even deadly. Almost all of the conditions can be caused by unnecessary ultraviolet (UV) radiation exposure, usually from excessive time in the sun or from the use of indoor tanning devices. It is alarming that every year, nearly one out of every three young white women aged 16–25 engages in indoor tanning. It's important to shatter the myth that tanned skin is a sign of health. And a “base” tan is not a “safe” tan. Tanned skin is damaged skin. Understanding the risk of UV exposure is crucial to protecting ourselves and our loved ones. That is why “The Surgeon General's Call to Action to Prevent Skin Cancer” is important for all of us. It outlines action steps we can all take—as individuals, parents, educators, employers, policy makers, health care professionals, and communities—to reverse this alarming trend. As a nation, we can all do more to address skin cancer as a serious public health challenge. Everyone is urged to find out more about the risk of skin cancer—and what we all can do to prevent it.

Author : Josep Malvehy,Ralph P. Braun,Susana Puig,Ashfaq A. Marghoob,Alfred W. Kopf
Publisher : CRC Press
Page : 106 pages
File Size : 41,5 Mb
Release : 2006-01-17
Category : Medical
ISBN : 9780203090343

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Handbook of Dermoscopy by Josep Malvehy,Ralph P. Braun,Susana Puig,Ashfaq A. Marghoob,Alfred W. Kopf Pdf

The rise in popularity of dermoscopy has meant that more and more practitioners need a ready reference to consult in a clinical setting where larger atlases are less practical. The Handbook of Dermoscopy features a wealth of photographs, checklists, and algorithms to assist in spot diagnoses. Coverage includes melanocytic lesions, seborrheic kerato

Author : Supriya Mallick,Goura K. Rath,Rony Benson
Publisher : Springer Nature
Page : 282 pages
File Size : 50,5 Mb
Release : 2019-11-25
Category : Medical
ISBN : 9789811500732

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Practical Radiation Oncology by Supriya Mallick,Goura K. Rath,Rony Benson Pdf

This book addresses the most relevant aspects of radiation oncology in terms of technical integrity, dose parameters, machine and software specifications, as well as regulatory requirements. Radiation oncology is a unique field that combines physics and biology. As a result, it has not only a clinical aspect, but also a physics aspect and biology aspect, all three of which are inter-related and critical to optimal radiation treatment planning. In addition, radiation oncology involves a host of machines/software. One needs to have a firm command of these machines and their specifications to deliver comprehensive treatment. However, this information is not readily available, which poses serious challenges for students learning the planning aspect of radiation therapy. In response, this book compiles these relevant aspects in a single source. Radiation oncology is a dynamic field, and is continuously evolving. However, tracking down the latest findings is both difficult and time-consuming. Consequently, the book also comprehensively covers the most important trials. Offering an essential ready reference work, it represents a value asset for all radiation oncology practitioners, trainees and students.

Author : Robert A. Schwartz
Publisher : Springer Science & Business Media
Page : 683 pages
File Size : 55,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461237907

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Skin Cancer by Robert A. Schwartz Pdf

The skin, uniquely positioned at the interface between the human body and the external world, plays a multifaceted role in the expression of cancer. Primary skin cancer is the most common cancer afflicting mankind and is rising in inci dence, despite the fact that it is often preventable. Besides primary cancer, the skin may show direct and indirect evidence of internal cancer, thus serving as a window to the body for both laymen and physicians alike. In addition, the acces sibility of the skin is useful for the study of carcinogenesis as well as cancer treat ment options. lowe much of my interest in skin cancer to Dr. Leon Goldman, the father of dermatologic laser surgery, and to Dr. Edmund Klein, the father of modern immunotherapy. We, at the Roswell Park Memorial Institute, were indeed for tunate to have a wealth of patients available for study. Many of the illustrations used in this book were of my patients at the Institute, and I kindly thank the fol lowing publications and their respective publishers for allowing me to reuse some of my photographs, most notably: Cancer Medicine (2nd edition), Journal of Surgical Oncology, Journal of the American Academy of Dermatology, Archives of Dermatology, Cancer, and Journal of Dermatologic Surgery and Oncology. We are very fortunate in this work to have some of the world's foremost authorities in their areas as contributors, such as Drs. Zackheim, Lambert, J.W. Trimble, J.R. Trimble, Jackson, Crutcher, Mashberg, Wick, Sidell, F. Helm, G.

Author : Daniel F. Roses,Matthew N. Harris,A. Bernard Ackerman
Publisher : W.B. Saunders Company
Page : 346 pages
File Size : 44,5 Mb
Release : 1983
Category : Medical
ISBN : UOM:39015004445824

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Diagnosis and Management of Cutaneous Malignant Melanoma by Daniel F. Roses,Matthew N. Harris,A. Bernard Ackerman Pdf

Author : Larry Nathanson
Publisher : Unknown
Page : 296 pages
File Size : 46,7 Mb
Release : 1986
Category : Medical
ISBN : UOM:39015011640524

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Management of Advanced Melanoma by Larry Nathanson Pdf

Author : Miroslav Blumenberg
Publisher : BoD – Books on Demand
Page : 214 pages
File Size : 40,9 Mb
Release : 2018-05-02
Category : Medical
ISBN : 9781789230949

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Human Skin Cancers by Miroslav Blumenberg Pdf

Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.

Author : Howard L. Kaufman,Janice M. Mehnert
Publisher : Springer
Page : 416 pages
File Size : 45,6 Mb
Release : 2015-11-24
Category : Medical
ISBN : 9783319225395

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Melanoma by Howard L. Kaufman,Janice M. Mehnert Pdf

Melanoma is one of the most types of cancer. When melanoma is detected at an early stage, treatment is highly successful, but outcomes can be poor when the disease is advanced. There has been significant progress in our understanding of the molecular biology, genetics, and immunology of melanoma over the past decade. This has been accompanied by rapid advances in therapeutic strategies for patients with melanoma. This book provides the clinician and the researcher with a broad understanding of the molecular and cellular pathogenesis of melanoma, explores the clinical characteristics and criteria for clinical and pathological staging of the disease, and provides an overview of current and evolving treatment strategies in the adjuvant, metastatic, and preventive settings. The treatment of special populations and rare variants of melanoma that often present particular clinical challenges is also covered. Authored by international experts in melanoma biology and clinical management, this volume concisely explains how to diagnose, treat, and prevent melanoma while reviewing advances in basic science and providing an overview of innovative approaches still under development.

Author : Franco Fraschini,Russel J. Reiter,Bojidar Stankov
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461519119

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The Pineal Gland and Its Hormones by Franco Fraschini,Russel J. Reiter,Bojidar Stankov Pdf

This volume contains the written contributions to the proceedings of a workshop related to the pineal gland and its hormones, which was held in Erice, Italy, on June 7 -June 13, 1994. This series of workshops, which began in 1982 and which have been held at four-year intervals since that time, has provided important continuity for advancing the state of knowledge relating to this very important investigative area. The enthusiasm for these conferences has increased steadily, as reflected in the number of individuals applying to attend and in the input of individuals who participate in the meeting. The 1994 meeting was important because of its timeliness. In the two years preceding the meeting a number of revolutionary discoveries were made relative to the actions of the pineal hormone melatonin. The Xenopus melatonin receptor was cloned, melatonin was demonstrated to be a potent antioxidant, the significance of melatonin receptors at the level of pars tuberalis in the regulation of the hypothalamo-pituitary-gonadal axis was questioned, a number of melatonin receptor analogues were discovered and successfully utilized, the mechanisms by which melatonin retards initiation and promotion of cancer was further elucidated, the clinical aspects of the pineal gland was re-scrutinized. Reviews relating to each of these subjects, as well as many others, are contained in this proceedings book. This volume represents an up-to-date repository for the most recent information related to this rapidly advancing field.

Author : Richard D. Carvajal
Publisher : Jones & Bartlett Publishers
Page : 156 pages
File Size : 43,9 Mb
Release : 2010-04-15
Category : Medical
ISBN : 9781449671587

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Dx/Rx: Melanoma by Richard D. Carvajal Pdf

Written by a medical oncologist, Dx/Rx Melanoma is ideal for medical trainees, general practitioners, dermatologists, and medical oncologists. This handy, pocket-sized book provides comprehensive, up-to-date information on the epidemiology, prevention, and management of melanoma of all stages. It includes an in-depth discussion of systemic treatment options in both the adjuvant and metastatic setting, as well as, a look at novel treatment options. Presented in a concise, easy-to-read format, this is an essential reference for on the ward or in the clinic! Key features include: Written by a medical oncologist with a thorough discussion of systemic therapy of melanoma In-depth look at novel treatments being developed for advanced melanoma, including a discussion of all major recent studies Discussion of the molecular biology of melanoma and the treatment implications

Author : Armand B Cognetta,William M. Mendenhall
Publisher : Springer Science & Business Media
Page : 256 pages
File Size : 41,6 Mb
Release : 2013-06-13
Category : Medical
ISBN : 9781461469865

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Radiation Therapy for Skin Cancer by Armand B Cognetta,William M. Mendenhall Pdf

Photon Radiation Therapy for Skin Malignancies is a vital resource for dermatologists interested in radiation therapy, including the physics and biology behind treatment of skin cancers, as well as useful and pragmatic formulas and algorithms for evaluating and treating them. Dermatology has always been a field that overlaps multiple medical specialties and this book is no exception, with its focus on both dermatologists and radiation oncologists. It is estimated that between 2010 and 2020, the demand for radiation therapy will exceed the number of radiation oncologists practicing in the U.S. tenfold, which could profoundly affect the ability to provide patients with sufficient access to treatment. Photon Radiation Therapy for Skin Malignancies enhances the knowledge of dermatologists and radiation oncologists and presents them with the most up-to-date information regarding detection, delineation and depth determination of skin cancers, and appropriate biopsy techniques. In addition, the book also addresses radiation therapy of the skin and the skin’s reactions to radiation therapy.

Author : Taku Fujimura,Yasuhiro Fujisawa,Atsushi Otsuka,Nikolas K. Haass
Publisher : Frontiers Media SA
Page : 129 pages
File Size : 45,9 Mb
Release : 2021-04-13
Category : Medical
ISBN : 9782889663279

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Recent Developments in Therapies and Diagnostic Tools for Melanoma and Non-melanoma Skin Cancer by Taku Fujimura,Yasuhiro Fujisawa,Atsushi Otsuka,Nikolas K. Haass Pdf

Author : Faruque Riffat,Carsten E. Palme,Michael Veness
Publisher : Springer
Page : 201 pages
File Size : 55,7 Mb
Release : 2015-09-30
Category : Medical
ISBN : 9788132224976

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Non-melanoma Skin Cancer of the Head and Neck by Faruque Riffat,Carsten E. Palme,Michael Veness Pdf

Non-melanoma skin cancer is a global public health issue. With an ever-increasing, and ageing, world population coupled with increasing numbers of immunosuppressed individuals the number of patients continues to rise. The head and neck is overwhelmingly the most frequent location for the development of a non-melanoma skin cancer and as such challenges the clinician with its complex anatomy. The importance of maintaining the aesthetics of the face and the function of the anatomy cannot be overstated, yet ultimately it is always the aim of curing a patient with the minimum of morbidity that clinicians strive for. However, the spectrum of presentations and subsequent management varies widely, ranging from patients with the ubiquitous low-risk mid-face basal cell carcinoma to those diagnosed with relatively uncommon but potentially life-threatening high-risk squamous cell carcinomas (e.g. involving metastatic lymph nodes or with perineural invasion present) and Merkel cell carcinomas.