Advances In Brain Vascular Research

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Advances in Brain Vascular Research

Author : Ana Clara Cristóvão,Liliana Bernardino,Raquel Ferreira
Publisher : Cambridge Scholars Publishing
Page : 202 pages
File Size : 49,5 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781527557239

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Advances in Brain Vascular Research by Ana Clara Cristóvão,Liliana Bernardino,Raquel Ferreira Pdf

The brain vasculature nurtures and regulates basic functions of the central nervous system (CNS), acting as a barrier against pathogens. This book provides in-depth and focused data on the characteristics, function and role of brain blood vessels in health and disease. It addresses topics such as vascular activity, cell-cell communication, and the role of the endothelium in the development of the most prevalent types of cerebrovascular disease, neurodegenerative disorders, cognitive impairment, and vascular abnormalities. It offers an updated view of the current state of microvascular biology and research, and thus supports the discovery of new therapeutic agents and procedures directed at several CNS disorders.

Advances in Brain Ischemia Research and Treatment: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 54 pages
File Size : 54,9 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481615228

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Advances in Brain Ischemia Research and Treatment: 2012 Edition by Anonim Pdf

Advances in Brain Ischemia Research and Treatment / 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Brain Ischemia in a concise format. The editors have built Advances in Brain Ischemia Research and Treatment / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Brain Ischemia in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Brain Ischemia Research and Treatment / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Advances in Brain Research

Author : Owen B. Williams,Garet I. Wilson
Publisher : Nova Biomedical Books
Page : 0 pages
File Size : 52,6 Mb
Release : 2012
Category : Brain
ISBN : 1620817136

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Advances in Brain Research by Owen B. Williams,Garet I. Wilson Pdf

This book presents and discusses topical data in the field of brain research. Topics discussed herein include nonpharmacological inhibition of cerebral dopaminergic activity; neuropsychology of the sense of agency; glucocorticoid-mediated regulation of tight junctions in brain vascular endothelium; the hierarchial organization and cerebral lateralisation of hand control and its relationship to language; and a unique cause of traumatic brain injury and all neuro-musculo-skeletal injuries.

Cerebral Small Vessel Disease

Author : Leonardo Pantoni,Philip B. Gorelick
Publisher : Cambridge University Press
Page : 375 pages
File Size : 45,9 Mb
Release : 2014-05
Category : Medical
ISBN : 9781107031661

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Cerebral Small Vessel Disease by Leonardo Pantoni,Philip B. Gorelick Pdf

Up-to-date discussion of the etiology, diagnosis, treatment, and prevention of this common cause of stroke and cognitive impairment.

The Cerebral Circulation

Author : Marilyn J. Cipolla
Publisher : Biota Publishing
Page : 82 pages
File Size : 49,7 Mb
Release : 2016-07-28
Category : Medical
ISBN : 9781615047239

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The Cerebral Circulation by Marilyn J. Cipolla Pdf

This e-book will review special features of the cerebral circulation and how they contribute to the physiology of the brain. It describes structural and functional properties of the cerebral circulation that are unique to the brain, an organ with high metabolic demands and the need for tight water and ion homeostasis. Autoregulation is pronounced in the brain, with myogenic, metabolic and neurogenic mechanisms contributing to maintain relatively constant blood flow during both increases and decreases in pressure. In addition, unlike peripheral organs where the majority of vascular resistance resides in small arteries and arterioles, large extracranial and intracranial arteries contribute significantly to vascular resistance in the brain. The prominent role of large arteries in cerebrovascular resistance helps maintain blood flow and protect downstream vessels during changes in perfusion pressure. The cerebral endothelium is also unique in that its barrier properties are in some way more like epithelium than endothelium in the periphery. The cerebral endothelium, known as the blood-brain barrier, has specialized tight junctions that do not allow ions to pass freely and has very low hydraulic conductivity and transcellular transport. This special configuration modifies Starling's forces in the brain microcirculation such that ions retained in the vascular lumen oppose water movement due to hydrostatic pressure. Tight water regulation is necessary in the brain because it has limited capacity for expansion within the skull. Increased intracranial pressure due to vasogenic edema can cause severe neurologic complications and death.

Neurovascular Neuropsychology

Author : Joanne Festa,Ronald Lazar
Publisher : Springer Science & Business Media
Page : 325 pages
File Size : 46,5 Mb
Release : 2009-06-12
Category : Medical
ISBN : 9780387707150

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Neurovascular Neuropsychology by Joanne Festa,Ronald Lazar Pdf

Neurovascular diseases and conditions, and their associated risk factors, represent a significant cause of cognitive disability in the United States and throughout the world. In the USA alone there are 750,000 new strokes each year, representing the number one cause of disability in the country. Hypertension, found in approximately 50 million Americans, has been shown to be associated with alterations of cognitive function, even in the absence of stroke and dementia. Recent studies of neurovascular disease have now revealed that neuropsychological function may be a more sensitive measure of brain integrity than coordination, motor or sensory function and correlates will with functional outcome measures. Neurovascular Neuropsychology focuses on focal and diffuse neurovascular disease in addition to systemic conditions in which cognition and behavior have been uniquely associated with different pathologic states. With an increasing number of patients being treated by healthcare professionals, Neurovascular Neuropsychology will prove to be a strong reference to consult in regards to neuropsychological syndromes.

Translational Research in Traumatic Brain Injury

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 46,9 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

New Developments in Dementia Prevention Research

Author : Kate Irving,Eef Hogervorst,Deborah Oliveira,Miia Kivipelto
Publisher : Routledge
Page : 213 pages
File Size : 52,5 Mb
Release : 2018-11-02
Category : Psychology
ISBN : 9781351122696

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New Developments in Dementia Prevention Research by Kate Irving,Eef Hogervorst,Deborah Oliveira,Miia Kivipelto Pdf

New Developments in Dementia Prevention Research addresses a dearth of knowledge about dementia prevention and shows the importance of considering the broader social impact of certain risk factors, including the role we each play in our own cognitive health throughout the lifespan. The book draws on primary and secondary research in order to investigate the relationship between modifiable factors, including vascular and psychosocial risks, that may affect the incidence of dementia. Bringing together world-leading expertise from applied science, medicine, psychology, health promotion, epidemiology, health economics, social policy and primary care, the book compares and contrasts scientific and service developments across a range of settings. Each chapter presents these themes in a way that will ensure best practice and further research in the field of dementia prevention is disseminated successfully throughout the world. Perhaps most importantly, chapters also question what type of social responsibility we are prepared to embrace in order to address the challenges inherent in dementia prevalence. New Developments in Dementia Prevention Research includes contributions from leading authorities in brain health and dementia prevention and provides an essential contribution to the discourse on dementia prevention. It will be of great interest to academics, researchers and postgraduate students engaged in the study of the psychological and social aspects of aging and dementia.

Introduction to Vascular Neurosurgery

Author : Justin R. Mascitelli,Mandy J. Binning
Publisher : Springer Nature
Page : 550 pages
File Size : 49,7 Mb
Release : 2022-01-12
Category : Medical
ISBN : 9783030881962

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Introduction to Vascular Neurosurgery by Justin R. Mascitelli,Mandy J. Binning Pdf

This book aims to cover the majority of neurovascular diseases and management. The first section reviews neurovascular anatomy, the basics of angiography, and the basics of craniotomies for neurovascular diseases. Next, an entire section is devoted to intracranial aneurysms, covering the natural history, subarachnoid hemorrhage, endovascular management, microsurgical management, and vasospasm. Following this, a number of chapters are devoted to stroke including natural history, mechanical thrombectomy, intracranial stenosis, Moyamoya disease, bypass surgery, vertebrobasilar insufficiency, intracerebral hemorrhage, sinus thrombosis, and the surgical and endovascular management of extracranial carotid disease. Next, the text covers vascular malformations including arteriovenous malformation, arteriovenous fistulas, carotid cavernous fistulas, vein of Galen malformations, spinal malformations, and cavernous malformations. Finally, the book discusses a few miscellaneous topics including more recent advances in neurovascular care such as venous sinus stenting for idiopathic intracranial hypertension and middle meningeal artery embolization for subdural hematoma. Written by experts in the field, Introduction to Vascular Neurosurgery provides a comprehensive summary of neurovascular disease and management. The book can be used as a daily reference and serves as a trusted resource for medical students, residents, fellows, and young attendings.

Alzheimer’s Turning Point

Author : Jack C. de la Torre
Publisher : Springer
Page : 256 pages
File Size : 50,8 Mb
Release : 2016-06-25
Category : Medical
ISBN : 9783319340579

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Alzheimer’s Turning Point by Jack C. de la Torre Pdf

This compelling text provides an overview of the available technology for early detection and therapeutic management of vascular risk factors to Alzheimer’s before severe cognitive impairment symptoms appear. Chapters bring the reader from the trackless clinical research that has characterized Alzheimer’s progress for the last 20 years, to a nexus of new ideas and concepts that can change our outlook of this dementia. In-depth examinations of various hypotheses, preventive measures, current and prospective treatments are openly and clearly explored. The author discusses in depth his proposal of the vascular hypothesis of Alzheimer's disease which has become a mother-lode for basic and clinical studies and a key approach to the prevention of this dementia.Alzheimer’s Turning Point offers professionals, students and those looking to learn more about this disorder a fresh clinical perspective of this devastating disease.

Vascular Endothelial Growth Factor Receptors—Advances in Research and Application: 2012 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 56 pages
File Size : 52,6 Mb
Release : 2012-12-26
Category : Science
ISBN : 9781481615198

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Vascular Endothelial Growth Factor Receptors—Advances in Research and Application: 2012 Edition by Anonim Pdf

Vascular Endothelial Growth Factor Receptors—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Vascular Endothelial Growth Factor Rece in a concise format. The editors have built Vascular Endothelial Growth Factor Receptors—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Vascular Endothelial Growth Factor Rece in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Vascular Endothelial Growth Factor Receptors—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Fragile Brain

Author : Kathleen Taylor
Publisher : Oxford University Press
Page : 320 pages
File Size : 53,8 Mb
Release : 2016-11-17
Category : Science
ISBN : 9780191039034

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The Fragile Brain by Kathleen Taylor Pdf

Neurodegenerative diseases, such as a stroke, Alzheimer's and dementia, are now tragically commonplace within the western world. Our brains are a strange and complex organ, and there is much to be discovered about what causes them to fail in such devastating ways. In this book Kathleen Taylor presents the ever-developing research into the cause and cure of these life-changing conditions, focusing on insights arising from the relatively new field of neuroimmunology - the increasing recognition of the important role of the immune system in the brain. Interweaving the latest scientific ideas on neurodegenerative diseases with accounts of the devastation which illnesses affecting the brain can cause to sufferers and to anyone who cares about them, The Fragile Brain is not only an important account of current research in this field, but a very personal study. As instances of dementia rise in our ageing populations, many harbour anxieties concerning the future.This book is about knowing the enemy.

Vascular Diseases: Advances in Research and Treatment: 2011 Edition

Author : Anonim
Publisher : ScholarlyEditions
Page : 1215 pages
File Size : 43,5 Mb
Release : 2012-01-09
Category : Medical
ISBN : 9781464920981

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Vascular Diseases: Advances in Research and Treatment: 2011 Edition by Anonim Pdf

Vascular Diseases: Advances in Research and Treatment: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Vascular Diseases. The editors have built Vascular Diseases: Advances in Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Vascular Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Vascular Diseases: Advances in Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Psychotherapy in an Age of Neuroscience

Author : Joel Paris
Publisher : Oxford University Press
Page : 217 pages
File Size : 54,9 Mb
Release : 2017
Category : Psychology
ISBN : 9780190601010

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Psychotherapy in an Age of Neuroscience by Joel Paris Pdf

Psychiatry, once proud of its biopsychosocial model, has now adopted a neuroscience-based approach that strongly favors psychopharmacological treatments and downplays the role of psychotherapies (or social interventions). This kind of practice can be sufficient for the psychoses, but it is neither evidence-based nor beneficial for patients with common mental disorders such as depression, anxiety, substance use, and personality disorders. Current practice derives from a theoretical model in which psychiatry is viewed primarily as an application of neuroscience, with little reference to the vast literature on psychology, social sciences, and psychotherapy. This work reviews research bearing on these issues, and it shows why existing data support a different set of conclusions from those held by many experts and most practitioners

The Blood Brain Barrier (BBB)

Author : Gert Fricker,Melanie Ott,Anne Mahringer
Publisher : Springer
Page : 169 pages
File Size : 49,5 Mb
Release : 2014-10-24
Category : Science
ISBN : 9783662437872

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The Blood Brain Barrier (BBB) by Gert Fricker,Melanie Ott,Anne Mahringer Pdf

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.