Translational Research In Traumatic Brain Injury

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 52,8 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498766579

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Daniel Laskowitz,Gerald Grant
Publisher : CRC Press
Page : 412 pages
File Size : 54,9 Mb
Release : 2016-04-21
Category : Medical
ISBN : 9781466584921

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz,Gerald Grant Pdf

Traumatic brain injury (TBI) remains a significant source of death and permanent disability, contributing to nearly one-third of all injury related deaths in the United States and exacting a profound personal and economic toll. Despite the increased resources that have recently been brought to bear to improve our understanding of TBI, the development of new diagnostic and therapeutic approaches has been disappointingly slow. Translational Research in Traumatic Brain Injury attempts to integrate expertise from across specialties to address knowledge gaps in the field of TBI. Its chapters cover a wide scope of TBI research in five broad areas: Epidemiology Pathophysiology Diagnosis Current treatment strategies and sequelae Future therapies Specific topics discussed include the societal impact of TBI in both the civilian and military populations, neurobiology and molecular mechanisms of axonal and neuronal injury, biomarkers of traumatic brain injury and their relationship to pathology, neuroplasticity after TBI, neuroprotective and neurorestorative therapy, advanced neuroimaging of mild TBI, neurocognitive and psychiatric symptoms following mild TBI, sports-related TBI, epilepsy and PTSD following TBI, and more. The book integrates the perspectives of experts across disciplines to assist in the translation of new ideas to clinical practice and ultimately to improve the care of the brain injured patient.

Author : Vicki Anderson,Keith Owen Yeates
Publisher : Cambridge University Press
Page : 247 pages
File Size : 54,8 Mb
Release : 2010-02-04
Category : Family & Relationships
ISBN : 9780521763325

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Pediatric Traumatic Brain Injury by Vicki Anderson,Keith Owen Yeates Pdf

Describes multidisciplinary, integrative, and translational approaches to research and practice in pediatric traumatic brain injury.

Author : Firas H. Kobeissy
Publisher : CRC Press
Page : 725 pages
File Size : 40,7 Mb
Release : 2015-02-25
Category : Science
ISBN : 9781466565999

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Brain Neurotrauma by Firas H. Kobeissy Pdf

Every year, an estimated 1.7 million Americans sustain brain injury. Long-term disabilities impact nearly half of moderate brain injury survivors and nearly 50,000 of these cases result in death. Brain Neurotrauma: Molecular, Neuropsychological, and Rehabilitation Aspects provides a comprehensive and up-to-date account on the latest developments in the area of neurotrauma, including brain injury pathophysiology, biomarker research, experimental models of CNS injury, diagnostic methods, and neurotherapeutic interventions as well as neurorehabilitation strategies in the field of neurotraum research. The book includes several sections on neurotrauma mechanisms, biomarker discovery, neurocognitive/neurobehavioral deficits, and neurorehabilitation and treatment approaches. It also contains a section devoted to models of mild CNS injury, including blast and sport-related injuries. Over the last decade, the field of neurotrauma has witnessed significant advances, especially at the molecular, cellular, and behavioral levels. This progress is largely due to the introduction of novel techniques, as well as the development of new animal models of central nervous system (CNS) injury. This book, with its diverse coherent content, gives you insight into the diverse and heterogeneous aspects of CNS pathology and/or rehabilitation needs.

Author : Vicki Anderson,Keith Owen Yeates
Publisher : Unknown
Page : 235 pages
File Size : 40,9 Mb
Release : 2010
Category : Brain-damaged children
ISBN : 0511683782

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Pediatric Traumatic Brain Injury by Vicki Anderson,Keith Owen Yeates Pdf

Describes multidisciplinary, integrative, and translational approaches to research and practice in pediatric traumatic brain injury.

Author : Daniel Laskowitz
Publisher : Unknown
Page : 128 pages
File Size : 53,7 Mb
Release : 2015
Category : Electronic
ISBN : OCLC:1020652839

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Translational Research in Traumatic Brain Injury by Daniel Laskowitz Pdf

Author : Michael E. Hoffer,Carey D. Balaban
Publisher : Academic Press
Page : 453 pages
File Size : 49,5 Mb
Release : 2018-11-24
Category : Medical
ISBN : 9780128125489

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Neurosensory Disorders in Mild Traumatic Brain Injury by Michael E. Hoffer,Carey D. Balaban Pdf

Mild traumatic Brain Injury (mTBI or Concussion) is an increasingly common public health issue in sports, military environments, and life in today’s active world. Despite a great deal of study and public attention to this disorder, knowledge about optimal diagnostic, prognostic, and treatment information remains lacking. Neurosensory symptoms have been shown to be the most frequent complications of mTBI in both the acute and chronic setting. Neurosensory Disorders in Mild Traumatic Brain Injury brings together both the basic science work as well as the clinical work in mTBI into one volume to provide a comprehensive examination of the neurosensory issues associated with this disorder. Coverage includes chapters on defining mild Traumatic Brain Injury, neurosensory consequences, neurosensory disorders in clinical practice, and diagnosis and treatment for neurosensory disorders in mTBI. This book is written for clinicians, researchers, residents and students in neurology and neuroscience. Provides a comprehensive examination of the neurosensory issues associated with mild Traumatic Brain Injury and concussion Brings together both the basic science work and the clinical work in mTBI into a single volume Helps clinicians understand the best diagnosis and treatment paths and puts current research into perspective for researchers

Author : Terje Sundstrøm,Per-Olof Grände,Niels Juul,Carsten Kock-Jensen,Bertil Romner,Knut Wester
Publisher : Springer Science & Business Media
Page : 417 pages
File Size : 41,8 Mb
Release : 2012-06-25
Category : Medical
ISBN : 9783642281266

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Management of Severe Traumatic Brain Injury by Terje Sundstrøm,Per-Olof Grände,Niels Juul,Carsten Kock-Jensen,Bertil Romner,Knut Wester Pdf

In order to reduce the number of deaths from severe head injuries, systematic management is essential. This book is a practical, comprehensive guide to the treatment of patients (both adults and children) with such injuries, from the time of initial contact through to the rehabilitation center. Sections are devoted to prehospital treatment, admission and diagnostics, acute management, and neurointensive care and rehabilitation. Evidence-based recommendations are presented for each diagnostic and therapeutic measure, and tips, tricks, and pitfalls are highlighted. Throughout, the emphasis is on the provision of sound clinical advice that will maximize the likelihood of an optimal outcome. Helpful flowcharts designed for use in daily routine are also provided. The authors are all members of the Scandinavian Neurotrauma Committee and have extensive practical experience in the areas they write about.

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Committee on Accelerating Progress in Traumatic Brain Injury Research and Care
Publisher : Unknown
Page : 244 pages
File Size : 54,8 Mb
Release : 2022-05-15
Category : Electronic
ISBN : 030949043X

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Traumatic Brain Injury by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Board on Health Sciences Policy,Committee on Accelerating Progress in Traumatic Brain Injury Research and Care Pdf

Every community is affected by traumatic brain injury (TBI). Causes as diverse as falls, sports injuries, vehicle collisions, domestic violence, and military incidents can result in injuries across a spectrum of severity and age groups. Just as the many causes of TBI and the people who experience it are diverse, so too are the physiological, cognitive, and behavioral changes that can occur following injury. The overall TBI ecosystem is not limited to healthcare and research, but includes the related systems that administer and finance healthcare, accredit care facilities, and provide regulatory approval and oversight of products and therapies. TBI also intersects with the wide range of community organizations and institutions in which people return to learning, work, and play, including the education system, work environments, professional and amateur sports associations, the criminal justice system, and others. Traumatic Brain Injury: A Roadmap for Accelerating Progress examines the current landscape of basic, translational, and clinical TBI research and identifies gaps and opportunities to accelerate research progress and improve care with a focus on the biological, psychological, sociological, and ecological impacts. This report calls not merely for improvement, but for a transformation of attitudes, understanding, investments, and care systems for TBI.

Author : Jennifer J. Vasterling,Richard A. Bryant,Terence M. Keane
Publisher : Guilford Press
Page : 324 pages
File Size : 47,6 Mb
Release : 2012-02-01
Category : Psychology
ISBN : 9781462503384

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PTSD and Mild Traumatic Brain Injury by Jennifer J. Vasterling,Richard A. Bryant,Terence M. Keane Pdf

Posttraumatic stress disorder (PTSD) and mild traumatic brain injury (mTBI) can each cause significant functional impairment--and these "invisible injuries" frequently co-occur. Events that lead to traumatic brain injury are often also psychologically traumatic. This authoritative volume brings together leading experts in PTSD and mTBI to explore the nature, consequences, and management of these interacting conditions. Presenting cutting-edge research and clinical practices, the book meets a growing need among mental health practitioners in both civilian and military contexts. The volume focuses on the complexities of caring for patients with comorbid PTSD and mTBI, whether caused by war-zone experiences, motor vehicle accidents, domestic violence or other interpersonal assaults, or sports concussions. Contributors examine the biological and psychosocial mechanisms underlying both disorders as well as potential ways they may affect each other. Commonly associated problems that may further complicate recovery--chronic pain and substance abuse--are also discussed in detail. Reviewing empirically based best practices in assessment and treatment, chapters offer recommendations for tailoring interventions to different patients' needs. Important topics include how to deal with dilemmas in evaluation and what treatment strategies work best for addressing overlapping symptoms. The book also considers ways to improve the structure and cost-effectiveness of providing care in this challenging area. Throughout, scientific controversies and unanswered questions are highlighted and promising directions for future research identified. Synthesizing knowledge from multiple disciplines, this is an essential reference for mental health practitioners and trauma specialists--including neuropsychologists, clinical psychologists, psychiatrists, and social workers--as well as graduate students and trainees.

Author : Svetlana Dambinova,Ronald L. Hayes,Kevin K. W. Wang
Publisher : Royal Society of Chemistry
Page : 247 pages
File Size : 40,5 Mb
Release : 2012
Category : Medical
ISBN : 9781849733892

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Biomarkers for Traumatic Brain Injury by Svetlana Dambinova,Ronald L. Hayes,Kevin K. W. Wang Pdf

Due to injuries sustained in sports and in combat, interest in traumatic brain injury (TBI) has never been greater. This book will fulfill a gap in understanding of what is occurring in the brain following injury that can subsequently be detected in biological fluids and imaging.

Author : Cathy Catroppa,Vicki Anderson,Miriam Beauchamp,Keith Yeates
Publisher : Routledge
Page : 237 pages
File Size : 46,9 Mb
Release : 2016-02-26
Category : Psychology
ISBN : 9781135246761

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New Frontiers in Pediatric Traumatic Brain Injury by Cathy Catroppa,Vicki Anderson,Miriam Beauchamp,Keith Yeates Pdf

New Frontiers in Pediatric Traumatic Brain Injury provides an evidence base for clinical practice specific to traumatic brain injury (TBI) sustained during childhood, with a focus on functional outcomes. It utilizes a biological-psychosocial conceptual framework consistent with the International Classification of Functioning, Disability and Health, which highlights that biological, psychological, and social factors all play a role in disease and children’s recovery from acquired brain injury. With its clinical perspective, it incorporates current and past research and evidence regarding advances that have occurred in outcomes, predictors, medical technology, and rehabilitation post-TBI. This book is great resource for established and new clinicians and researchers, graduate students, and postdoctoral fellows who work in the field of pediatric TBI, including psychologists, neuropsychologists, pediatricians, and psychiatrists.

Author : Kevin Wang
Publisher : Oxford University Press, USA
Page : 529 pages
File Size : 50,9 Mb
Release : 2018-11-16
Category : Medical
ISBN : 9780190279431

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Neurotrauma by Kevin Wang Pdf

Neurotrauma: A Comprehensive Textbook on Traumatic Brain Injury and Spinal Cord Injury aims to bring together the latest clinical practice and research in the filed of two forms of trauma to the central nervous system: namely traumatic brain injury (TBI) and spinal cord injury (SCI). Nationally, more 1.9 million Americans sustain a traumatic brain injury annually. In parallel, there are an estimate of 12,000 new cases of SCI in the United States annually. In addition, approximately 1.2 million people live with paralysis due to SCI. In recent years, dramatic advancements in the field have resulted in much improved outcomes for patients and higher standards of care. This volume details the latest research and clinical practice in the treatment of neurotrauma, in a comprehensive but easy-to-follow format. Neurotrauma is a valuable resource for any clinician involved in caring for TBI and SCI patients, clinical research professionals, researchers, medical and graduate students, and nurse specialists.

Author : Bridget Martinez
Publisher : Royal Society of Chemistry
Page : 366 pages
File Size : 50,5 Mb
Release : 2017-11-23
Category : MEDICAL
ISBN : 9781782629504

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Acute Brain Impairment by Bridget Martinez Pdf

Author : P. Michael Conn
Publisher : Academic Press
Page : 776 pages
File Size : 47,9 Mb
Release : 2016-09-28
Category : Medical
ISBN : 9780128025963

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Conn's Translational Neuroscience by P. Michael Conn Pdf

Conn’s Translational Neuroscience provides a comprehensive overview reflecting the depth and breadth of the field of translational neuroscience, with input from a distinguished panel of basic and clinical investigators. Progress has continued in understanding the brain at the molecular, anatomic, and physiological levels in the years following the 'Decade of the Brain,' with the results providing insight into the underlying basis of many neurological disease processes. This book alternates scientific and clinical chapters that explain the basic science underlying neurological processes and then relates that science to the understanding of neurological disorders and their treatment. Chapters cover disorders of the spinal cord, neuronal migration, the autonomic nervous system, the limbic system, ocular motility, and the basal ganglia, as well as demyelinating disorders, stroke, dementia and abnormalities of cognition, congenital chromosomal and genetic abnormalities, Parkinson's disease, nerve trauma, peripheral neuropathy, aphasias, sleep disorders, and myasthenia gravis. In addition to concise summaries of the most recent biochemical, physiological, anatomical, and behavioral advances, the chapters summarize current findings on neuronal gene expression and protein synthesis at the molecular level. Authoritative and comprehensive, Conn’s Translational Neuroscience provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, as well as a clear demonstration of their emerging diagnostic and therapeutic importance. Provides a fully up-to-date and readily accessible guide to brain functions at the cellular and molecular level, while also clearly demonstrating their emerging diagnostic and therapeutic importance Features contributions from leading global basic and clinical investigators in the field Provides a great resource for researchers and practitioners interested in the basic science underlying neurological processes Relates and translates the current science to the understanding of neurological disorders and their treatment