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Author : Vicente Felipo
Publisher : Springer Science & Business Media
Page : 280 pages
File Size : 47,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461559450
Proceedings of an international symposiu, held in Valencia, Spain, December 2-4, 1996
Author : Santiago Grisolía,Vicente Felipo
Publisher : Springer Science & Business Media
Page : 150 pages
File Size : 42,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461524847
This volume contains the papers presented in the International Summer Course on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy," which was one of the prestigious Summer Course, of the Complutense University of Madrid held in EI Escorial, Spain, during August 10-14, 1992. Liver cirrhosis is one of the main causes of death in western countries. In addition there is a series of liver dysfunctions including fulminant hepatic failure, Reye's syndrome and congenital defects of urea cycle enzymes that could lead to hepatic encephalopathy, coma and death. As a consequence of impaired liver function, the ability to detoxify ammonia by its incorporation into urea is diminshed, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. A part of the book is therefore devoted to the study of certain aspects of ammonia metabolism such as the regulation of the urea cycle, the main mechanism of ammonia detoxification in mammals, which is located mainly in the liver. The metabolism of ammonia in other tissues, including brain, is also presented, as well as the effects of hyperammonemia on brain metabolism and function and on brain microtubules. The control of cerebral protein breakdown is reviewed. The classical and some recently proposed clinical treatments as well as nutritional considerations in the management of patients with liver failure are also discussed.
Author : Robert S. Brown Jr
Publisher : Elsevier Health Sciences
Page : 161 pages
File Size : 52,7 Mb
Release : 2015-10-19
Category : Medical
ISBN : 9780323376044
Dr. Brown provides a timely upate on the clinical diagnosis and management of Hepatic Encephalopathy. His issue addresses current hot topics including Role of NH4 in Pathogenesis of Hepatic Encephalopathy; How to diagnose and manage HE in fulminant hepatic failure; New methods of Brain Imaging and testing (eg PET) and Hepatic Encephalopathy; Management New agents for HE (focus on NH4 lowering drugs used in UCD); Legal responsibility of MD when he diagnoses HE; Diets in Encephalopathy; and Neurological manifestations of HE.
Author : Kevin D. Mullen,Ravi K. Prakash
Publisher : Springer Science & Business Media
Page : 251 pages
File Size : 46,8 Mb
Release : 2012-05-30
Category : Medical
ISBN : 9781617798368
Because of the increasing burden of hepatitis C and fatty liver disease, there is an explosion in the prevalence of chronic liver failure and hence its complications. The onset of Hepatic Encephalopathy (HE) in these patients has a significant impact on the quality of life, morbidity and mortality. Unfortunately, the approach observed by most clinicians to this complex disorder is minimalistic. This book provides a comprehensive review on pathophysiology and clinically important aspects in HE. Topics in basic physiology, nitrogen metabolism, new insights into pathogenesis and brain edema are covered in great detail. The authors have made a special effort by simplifying the complex aspects of pathogenesis and diagnosis so that it can be easily understood and applied clinically. This volume also focuses on recent developments regarding diagnoses of subtle forms of HE, also known as minimal or covert HE as well as on new treatments. Hepatic Encephalopathy will be of great value to gastroenterologists, hepatologists, pathologists, medical residents, fellows, internists and general practitioners who treat patients with hepatic encephalopathy.
Author : Gunter Kleinberger
Publisher : S. Karger AG (Switzerland)
Page : 792 pages
File Size : 47,7 Mb
Release : 1984
Category : Amino acid metabolism
ISBN : UOM:39015007121091
Author : Vicente Felipo,Santiago Grisolía
Publisher : Springer
Page : 0 pages
File Size : 55,7 Mb
Release : 2012-10-21
Category : Medical
ISBN : 1461358205
This volume contains the papers presented at the International Symposium on "Cirrhosis, Hyperammonemia and Hepatic Encephalopathy", held in Valencia, Spain, January 24th-27th, 1994. Liver cirrhosis and other hepatic dysfunctions such as fulminant hepatic failure and congenital defects of urea cycle enzymes can lead to hepatic encephalopathy, coma and death. Hepatic encephalopathy is one of the main causes of death in western countries. The ability to detoxify ammonia by its incorporation into urea is diminished by impaired liver function, resulting in increased ammonia levels in blood and brain. Hyperammonemia is considered one of the main factors in the mediation of hepatic encephalopathy and the classical clinical treatments are directed towards reducing blood ammonia levels. However, the molecular bases of the pathogenesis of hepatic encephalopathy and the role of hyperammonemia in this process remain unclear and several hypotheses have been proposed. To clarify the mechanisms involved in hepatic encephalopathy and hyperammonemia suitable animal models are necessary. The animal models available and the ideal features of an animal model are presented in the initial part of the book.
Author : Anonim
Publisher : Unknown
Page : 524 pages
File Size : 42,7 Mb
Release : 1997
Category : Ammonia
ISBN : 0947678115
Author : E. Anthony Jones,Alfred J. Meijer,Robert A.F.M. Chamuleau
Publisher : Springer Science & Business Media
Page : 437 pages
File Size : 44,7 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789401001595
Encephalopathy and Nitrogen Metabolism in Liver Failure contains research reports and state-of-the-art reviews that were presented at the 11th International Symposium on Hepatic Encephalopathy and Nitrogen Metabolism in relation to liver disease, that was held in Amsterdam, The Netherlands from 30 May to 1 June, 2002. Themes covered include the metabolism of ammonia and amino acids in relation to liver disease, the assessment of hepatic encephalopathy (HE), minimal HE, animal models of HE, neuropsychiatric dysfunction in patients with chronic liver disease, the pathogenesis of HE, the astrocyte in liver disease, acute liver failure and cerebral edema, treatment of HE and artificial liver support systems. This volume provides an indispensable source of important new research findings and ideas for clinicians and biomedical scientists working in the field of HE and nitrogen metabolism in relation to liver disease.
Author : Anonim
Publisher : ScholarlyEditions
Page : 111 pages
File Size : 49,5 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781481608862
Metabolic Brain Diseases—Advances in Research and Treatment: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Metabolic Brain Diseases in a concise format. The editors have built Metabolic Brain Diseases—Advances in Research and Treatment: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Metabolic Brain Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Metabolic Brain Diseases—Advances in Research and Treatment: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
Author : Finn Bengtsson
Publisher : Springer
Page : 600 pages
File Size : 47,8 Mb
Release : 1991-04-24
Category : Medical
ISBN : UOM:39015019853871
Author : Cihan Yurdaydin,Hakan Bozkaya
Publisher : Unknown
Page : 482 pages
File Size : 42,6 Mb
Release : 2000
Category : Hepatic encephalopathy
ISBN : 9759366703
Author : Livio Capocaccia,Manuela Merli,Oliviero Riggio
Publisher : CRC-Press
Page : 672 pages
File Size : 45,9 Mb
Release : 1994-12-27
Category : Medical
ISBN : 084938964X
This is a comprehensive reference covering the advances in hepatic encephalopathy (HE) and metabolic nitrogen exchange. Written by experts in their fields, the text discusses various aspects of hepatic nitrogen metabolism, protein metabolism, renal ammonia metabolism, neurobiology and neuropharmacology, and ammonia in the pathogenesis of HE. Benzodiazepine receptor ligands in the pathogenesis of HE are featured, and amino acids, amines, and zinc in the pathogeneis of HE are investigated. Studies done with various animal models are included. New techniques, MR spectroscopy and imaging, are highlighted. Steps for the diagnosis and assessment of HE are provided, and the effects of therapy are examined. Useful information is given regarding the metabolic aspects of liver cirrhosis and liver cell physiology.
Author : Pere Ginès,Patrick S Kamath,Vicente Arroyo
Publisher : Springer Science & Business Media
Page : 590 pages
File Size : 55,9 Mb
Release : 2010-11-03
Category : Medical
ISBN : 9781607618669
Chronic liver failure is a frequent condition in clinical practice that encompasses all manifestations of patients with end-stage liver diseases. Chronic liver failure is a multiorgan syndrome that affects the liver, kidneys, brain, heart, lungs, adrenal glands, and vascular, coagulation, and immune systems. Chronic Liver Failure: Mechanisms and Management covers for the first time all aspects of chronic liver failure in a single book, from pathogenesis to current management. Each chapter is written by a worldwide known expert in their area and all provide the latest state-of-the-art knowledge. This volume is specifically designed to provide answers to clinical questions to all doctors dealing with patients with liver diseases, not only clinical gastroenterologists and hepatologists, but also to internists, nephrologists, intensive care physicians, and transplant surgeons.
Author : D. Häussinger,G. Kirchels,F. Schless
Publisher : Springer
Page : 0 pages
File Size : 43,6 Mb
Release : 2014-11-29
Category : Medical
ISBN : 9400788576
Hepatic Encephalopathy and Nitrogen Metabolism is an interdisciplinary symposium bringing together basic science and clinical applications. It contains up-to-date research findings at the highest scientific level.
Author : Georgios Tsoulfas,Luis Rodrigo
Publisher : BoD – Books on Demand
Page : 250 pages
File Size : 48,9 Mb
Release : 2019-11-27
Category : Medical
ISBN : 9781789850659
The goal of this book is to present a review of the different categories of liver disease, as well as address the role of surgery in managing these complex diseases. The book includes chapters written by international experts on the most current indications and guidelines regarding the diagnoses and management of liver diseases, as well as a variety of technical elements involved with the surgical procedures. Different surgical techniques involved in performing a hepatectomy will be discussed, including various instruments used, as well as the effect of modern technology as evidenced by novel procedures. An important focus of the book has been identifying the proper place of all these hepatectomy methods in the armamentarium of the experienced hepatobiliary surgeon, including the role of locoregional treatments such as ablation and embolization as adjuncts. Finally, the role of hepatectomy compared to orthotopic liver transplantation is discussed, so that the reader can have a well-rounded picture of the challenges and opportunities involved. Overall, this book has the potential to serve as an invaluable "tool" for both the hepatologist and the internist, as well as for the hepatic surgeon