Agents Of Bioterrorism

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Bioterrorism and Infectious Agents

Author : I.W. Fong,Kenneth Alibek
Publisher : Springer Science & Business Media
Page : 284 pages
File Size : 52,5 Mb
Release : 2010-03-18
Category : Medical
ISBN : 9781441912664

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Bioterrorism and Infectious Agents by I.W. Fong,Kenneth Alibek Pdf

Compiled by two leading experts in the field, this volume provides a concise, timely, and authoritative review of some of the most problematic infections of the new century. It presents issues and new ideas for preventing and controlling infectious diseases.

Agents of Bioterrorism

Author : Geoffrey Zubay
Publisher : Columbia University Press
Page : 386 pages
File Size : 49,7 Mb
Release : 2008-02-14
Category : History
ISBN : 9780231518130

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Agents of Bioterrorism by Geoffrey Zubay Pdf

This new work offers a clear and thorough account of the threats posed by bioterrorism from the perspective of biologists. The authors examine thirteen disease-causing agents, including those responsible for anthrax, the plague, smallpox, influenza, and SARS. Each chapter considers a particular pathogen from the standpoint of its history, molecular biology, pathology, clinical presentation, diagnosis, weaponization, and defenses. The book also examines strategies for making vaccines and protecting the population in a bioterror attack.

Handbook on Biological Warfare Preparedness

Author : S.J.S. Flora,Vidhu Pachauri
Publisher : Academic Press
Page : 306 pages
File Size : 55,8 Mb
Release : 2019-10-05
Category : Medical
ISBN : 9780128120552

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Handbook on Biological Warfare Preparedness by S.J.S. Flora,Vidhu Pachauri Pdf

Handbook on Biological Warfare Preparedness provides detailed information on biological warfare agents and their mode of transmission and spread. In addition, it explains methods of detection and medical countermeasures, including vaccine and post-exposure therapeutics, with specific sections detailing diseases, their transmission, clinical signs and symptoms, diagnosis, treatment, vaccines, prevention and management. This book is useful reading for researchers and advanced students in toxicology, but it will also prove helpful for medical students, civil administration, medical doctors, first responders and security forces. As the highly unpredictable nature of any event involving biological warfare agents has given rise to the need for the rapid development of accurate detection systems, this book is a timely resource on the topic. Introduces different bacterial and viral agents, including Ebola and other emerging threats and toxins Discusses medical countermeasures, including vaccines and post-exposure therapeutics Includes a comprehensive review of current methods of detection

Chemical and Biological Terrorism

Author : Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine
Publisher : National Academies Press
Page : 303 pages
File Size : 42,8 Mb
Release : 1999-02-26
Category : History
ISBN : 9780309523141

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Chemical and Biological Terrorism by Committee on R&D Needs for Improving Civilian Medical Response to Chemical and Biological Terrorism Incidents,Institute of Medicine Pdf

The threat of domestic terrorism today looms larger than ever. Bombings at the World Trade Center and Oklahoma City's Federal Building, as well as nerve gas attacks in Japan, have made it tragically obvious that American civilians must be ready for terrorist attacks. What do we need to know to help emergency and medical personnel prepare for these attacks? Chemical and Biological Terrorism identifies the R&D efforts needed to implement recommendations in key areas: pre-incident intelligence, detection and identification of chemical and biological agents, protective clothing and equipment, early recognition that a population has been covertly exposed to a pathogen, mass casualty decontamination and triage, use of vaccines and pharmaceuticals, and the psychological effects of terror. Specific objectives for computer software development are also identified. The book addresses the differences between a biological and chemical attack, the distinct challenges to the military and civilian medical communities, and other broader issues. This book will be of critical interest to anyone involved in civilian preparedness for terrorist attack: planners, administrators, responders, medical professionals, public health and emergency personnel, and technology designers and engineers.

The Arenaviridae

Author : Maria S. Salvato
Publisher : Springer Science & Business Media
Page : 417 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461530282

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The Arenaviridae by Maria S. Salvato Pdf

In this volume, a distinguished international group of contributors present the latest molecular, organismal, and epidemiological research on arenaviruses. Their work will broaden both the clinician's and the researcher's knowledge of basic mechanisms of immunological tolerance, viral immunosuppression, the nature of protective immune responses to vaccination, and viral effects on cell functions.

Biological Agents

Author : Shiv Kant Prasad
Publisher : Discovery Publishing House
Page : 294 pages
File Size : 55,7 Mb
Release : 2009
Category : Biological agents
ISBN : 8183563813

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Biological Agents by Shiv Kant Prasad Pdf

Radiation Inactivation of Bioterrorism Agents

Author : L.G. Gazsó,C.C. Ponta
Publisher : IOS Press
Page : 216 pages
File Size : 47,6 Mb
Release : 2005-02-25
Category : History
ISBN : 9781607501091

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Radiation Inactivation of Bioterrorism Agents by L.G. Gazsó,C.C. Ponta Pdf

The use of and problems associated with biological weapons have been of concern to NATO and non-NATO military organizations for many years. Until recently, most of the readily available literature addressed the military issues associated with the possible use of biological weapons on the battlefield, the medical effects of the various agents, and what was known about medical prophylaxis and treatments. Information on other needed countermeasures, such as decontamination, or public health issues associated with exposure of civilian populations, were largely overlooked. This perspective changed dramatically after the contamination of the US Mail system with powdered anthrax spores. Among the significant problems and defensive weaknesses that the anthrax attack revealed was the importance, but lack of established industrial-scale decontamination methods for large volumes of heterogeneous objects or for complex physical environments. Ultimately, these two microbial decontamination problems were solved in very different ways. The contaminated mail was treated with ionizing radiation while the contaminated government buildings were treated with vapor / gas-phase chemicals. Both the decontamination of the mail and establishing a process for prophylactic treatment of the mail, were solved relatively quickly. This was in large part due to the robust radiation biology and technical base derived from the industrial use of ionizing radiation. Contributing to the speed of response was the fact that the attack occurred within the United States and in the 'home town' of many of the technical experts and decision makers, allowing official response to be coordinated rapidly.

Bioterrorism and Biocrimes

Author : W. Seth Carus,Center for Counterproliferation Research
Publisher : The Minerva Group, Inc.
Page : 224 pages
File Size : 51,5 Mb
Release : 2002
Category : History
ISBN : 1410100235

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Bioterrorism and Biocrimes by W. Seth Carus,Center for Counterproliferation Research Pdf

The working paper is divided into two main parts. The first part is a descriptive analysis of the illicit use of biological agents by criminals and terrorists. It draws on a series of case studies documented in the second part. The case studies describe every instance identifiable in open source materials in which a perpetrator used, acquired, or threatened to use a biological agent. While the inventory of cases is clearly incomplete, it provides an empirical basis for addressing a number of important questions relating to both biocrimes and bioterrorism. This material should enable policymakers concerned with bioterrorism to make more informed decisions. In the course of this project, the author has researched over 270 alleged cases involving biological agents. This includes all incidents found in open sources that allegedly occurred during the 20th Century. While the list is certainly not complete, it provides the most comprehensive existing unclassified coverage of instances of illicit use of biological agents.

Responsible Research with Biological Select Agents and Toxins

Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Laboratory Security and Personnel Reliability Assurance Systems for Laboratories Conducting Research on Biological Select Agents and Toxins
Publisher : National Academies Press
Page : 188 pages
File Size : 53,6 Mb
Release : 2010-02-12
Category : Political Science
ISBN : 9780309145350

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Responsible Research with Biological Select Agents and Toxins by National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Laboratory Security and Personnel Reliability Assurance Systems for Laboratories Conducting Research on Biological Select Agents and Toxins Pdf

The effort to understand and combat infectious diseases has, during the centuries, produced many key advances in science and medicine-including the development of vaccines, drugs, and other treatments. A subset of this research is conducted with agents that, like anthrax, not only pose a severe threat to the health of humans, plants, and animals but can also be used for ill-intended purposes. Such agents have been listed by the government as biological select agents and toxins. The 2001 anthrax letter attacks prompted the creation of new regulations aimed at increasing security for research with dangerous pathogens. The outcome of the anthrax letter investigation has raised concern about whether these measures are adequate. Responsible Research with Biological Select Agents and Toxins evaluates both the physical security of select agent laboratories and personnel reliability measures designed to ensure the trustworthiness of those with access to biological select agents and toxins. The book offers a set of guiding principles and recommended changes to minimize security risk and facilitate the productivity of research. The book recommends fostering a culture of trust and responsibility in the laboratory, engaging the community in oversight of the Select Agent Program, and enhancing the operation of the Select Agent Program.

Defence Against Bioterrorism

Author : Vladan Radosavljevic,Ines Banjari,Goran Belojevic
Publisher : Springer
Page : 272 pages
File Size : 45,5 Mb
Release : 2018-03-22
Category : Science
ISBN : 9789402412635

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Defence Against Bioterrorism by Vladan Radosavljevic,Ines Banjari,Goran Belojevic Pdf

This volume is based on a multidisciplinary approach towards biological and chemical threats that can, and have been previously used in bioterrorism attacks around the globe. Current knowledge and evidence-based principles from the fields of synthetic biology, microbiology, plant biology, chemistry, food science, forensics, tactics, infective medicine, psychology and others are compiled to address numerous aspects and the complexity of bioterrorism attacks. The main focus is on biological threats, especially in the context of synthetic biology and its emerging findings that can be observed as possible threat and tool. The book examines microorganisms and their possible use in forensics, i.e. as possible detection tool that could enable fast and precise detection of possible treats. A number of plant derived components are also discussed as possible agents in bioterrorism attacks, and in relation to infectious disease pathology. Another integral part is food safety, especially in terms of large food supply chains, like airline caterings, institutionalized kitchens etc. Food can be observed as a possible mean of delivery of various agents (biological and chemical) for bioterrorism attacks. Steps on how to recognize specific critical points in a food supply chain, along with proposed corrective activities are discussed. Examples from around the globe, along with the methodological approach on how to differentiate bioterrorism attacks from other epidemics are provided. However, epidemics are also discussed in the context of migrations, with the special emphasis on the current refugee migrations that affect not only Europe, but also the United States. The book will be of interest to experts from various fields of science as well as professionals working in the field. The book encompasses examples and tools developed for easier, more specific, and faster detection of possible bioterrorism treats, along with proposed actions for some aspects of a bioterrorism attack.

Biosecurity and Bioterrorism

Author : Jeffrey Ryan
Publisher : Butterworth-Heinemann
Page : 394 pages
File Size : 46,7 Mb
Release : 2016-02-18
Category : Political Science
ISBN : 9780128020579

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Biosecurity and Bioterrorism by Jeffrey Ryan Pdf

Biosecurity and Bioterrorism, Second Edition, takes a holistic approach to biosecurity, with coverage of pathogens, prevention, and response methodology. It addresses these hazards in the context of vulnerability assessments and the planning strategies government and industry can use to prepare for and respond to such events. The book is organized into four thematic sections: Part I provides a conceptual understanding of biowarfare, bioterrorism and the laws we have to counteract this; Part II investigates known bioagents and the threat from emerging diseases; Part III focuses on agricultural terrorism and food security; and Part IV outlines international, US, and local initiatives for biodefense and biosecurity. Case studies illustrate biodefense against both intentional terrorism and natural outbreaks. Covers emerging threats of pandemic influenza, antibiotic resistant strains of bacterial pathogens, and severe respiratory diseases caused by novel viruses Offers increased international coverage, including initiatives to counter biological weapons and threats, and food security Updated throughout with latest protocols for dealing with biological threats and new case studies Includes online instructor ancillaries - PowerPoint lecture slides, test questions, and an instructor manual, for increased classroom functionality

Surveillance and Detection

Author : Barbara F. Bullock
Publisher : Unknown
Page : 46 pages
File Size : 45,5 Mb
Release : 2002
Category : Biological weapons
ISBN : STANFORD:36105111519216

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Surveillance and Detection by Barbara F. Bullock Pdf

Perhaps the most frightening apparition of our times is the possibility that a biological agent (bacterim, virus, or toxin) will be used to attack our unprotected civilian population and inflict mass casualties. Until the Fall of 2001, anthrax attacks delivered through the mail to various U.S. senators, to the Governor of New York, and to various media offices, the previously expected use of a weapon of mass destruction against the United States has been a nuclear device that explodes or a chemical cloud that is set adrift. However, today, of all the weapons of mass destruction (nuclear, chemical, and biological), the biological weapons are the most feared by many defense experts but these are the ones that our country is least prepared to deal with Like the concept of a "nuclear winter," the potential destructiveness of a biological attack can come in many forms and is presently very hard to detect and control, and its results could be catastrophic. The unleashing of biological agents against an unprotected civilian population also, in some cases, constitutes the ultimate medical disaster with the capability to completely overwhelm the present health care system. Patients might go to health facilities in unprecedented numbers and demands for intensive care could well exceed available medical resources. Discerning the threat of bioweapons and appropriate responses to them are critical if we are to prevent the devastating effects of bioterrorism.

Microorganisms and Bioterrorism

Author : Burt Anderson,Herman Friedman,Mauro Bendinelli
Publisher : Springer Science & Business Media
Page : 251 pages
File Size : 48,7 Mb
Release : 2007-05-26
Category : Science
ISBN : 9780387281599

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Microorganisms and Bioterrorism by Burt Anderson,Herman Friedman,Mauro Bendinelli Pdf

The purpose of this book is to bring together, in a single volume, the most up-to-date information concerning microbes with potential as bioterrorist weapons. The primary audience includes microbiologists, including bacteriologists, virologists and mycologists, in academia, government laboratories and research institutes at the forefront of studies concerning microbes which have potential as bioterrorist weapons, public health physicians and researchers and scientists who must be trained to deal with bioterrorist attacks as well as laboratory investigators who must identify and characterize these microorganisms from the environment and from possibly infected patients.

Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Board on Life Sciences,Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents
Publisher : National Academies Press
Page : 87 pages
File Size : 47,7 Mb
Release : 2006-09-07
Category : Political Science
ISBN : 9780309102117

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Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,Board on Life Sciences,Committee on Animal Models for Testing Interventions Against Aerosolized Bioterrorism Agents Pdf

The National Institute of Allergy and Infectious Diseases (NIAID) gives the highest priority to developing countermeasures against bioterrorism agents that are highly infective when dispersed in aerosol form. Developing drugs to prevent or treat illnesses caused by bioterrorism agents requires testing their effectiveness in animals since human clinical trials would be unethical. At the request of NIAID, the National Academies conducted a study to examine how such testing could be improved. Overcoming Challenges to Develop Countermeasures Against Aerosolized Bioterrorism Agents provides recommendations to researchers on selecting the kinds of animal models, aerosol generators, and bioterrorism agent doses that would produce conditions that most closely mimic the disease process in humans. It also urges researchers to fully document experimental parameters in the literature so that studies can be reproduced and compared. The book recommends that all unclassified data on bioterrorism agent studies-including unclassified, unpublished data from U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID)-be published in the open literature. The book also calls on the U.S. Food and Drug Administration to improve the process by which bioterrorism countermeasures are approved based on the results of animal studies.

Portable Chemical Sensors

Author : Dimitrios P. Nikolelis
Publisher : Springer Science & Business Media
Page : 350 pages
File Size : 40,6 Mb
Release : 2012-02-02
Category : Science
ISBN : 9789400728721

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Portable Chemical Sensors by Dimitrios P. Nikolelis Pdf

Biosensors are making a large impact in environmental, food, biomedical, and other applications. In comparison to standard analytical detection methods, such as minimal sample preparation and handling, they offer advantages including real time detection, rapid detection of the analytes of concern, use of non-skilled personnel, and portability. The aim of this book is to focus on research related to the rapid detection of agents and weapons of bioterrorism and provide a comprehensive review of the research topics most pertinent to advancing devices applicable to the rapid real-time detection of toxicants such as microbes, pathogens, toxins, or nerve gases. The ongoing war on terrorism and the rising security concerns are driving the need for newer faster biosensors against bio-warfare agents for both military and civil defence applications. The volume brings together contributions from the most eminent international researchers in the field, covering various aspects of work not so far published in any scientific journal and often going beyond the “state of art “ . Readers of these review articles will learn new technological schemes that can lead to the construction of devices that will minimize the risk of bio-terrorism.