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Alginates: Biology and Applications by Bernd H. A. Rehm Pdf
"Alginates: Biology and Applications" provides an overview of the state of art of alginate material properties, genetics and the molecular mechanisms underlying alginate biosynthesis as well as applications of tailor-made alginates in medicine, food and biotechnology. Topics treated are: material properties of alginates, alginate production: precursor biosynthesis, polymerization and secretion, bacterial system for alginate uptake and degradation, enzymatic alginate modification, alginate gene regulation, role of alginate in bacterial biofilms, microbial production of alginates: physiology and process aspects, alginate-based blends and nano/microbeads, applications of alginates in food, alginate and its comonomer mannuronic acid: medical relevance as drugs.
Alginates: Biology and Applications by Bernd H. A. Rehm Pdf
"Alginates: Biology and Applications" provides an overview of the state of art of alginate material properties, genetics and the molecular mechanisms underlying alginate biosynthesis as well as applications of tailor-made alginates in medicine, food and biotechnology. Topics treated are: material properties of alginates, alginate production: precursor biosynthesis, polymerization and secretion, bacterial system for alginate uptake and degradation, enzymatic alginate modification, alginate gene regulation, role of alginate in bacterial biofilms, microbial production of alginates: physiology and process aspects, alginate-based blends and nano/microbeads, applications of alginates in food, alginate and its comonomer mannuronic acid: medical relevance as drugs.
Properties and Applications of Alginates by Irem Deniz,Esra Imamoglu,Tugba Keskin Gundogdu Pdf
Alginates are biodegradable, biocompatible, renewable, and natural polysaccharides in brown marine algae. Properties and Applications of Alginates provides an overview of the state of the art of chemical and material properties of alginates and biomedical and nanotechnology mechanisms underlying alginate biosynthesis. It discusses alginate-based materials’ fundamentals that combine research and technological advances with current limitations. Moreover, novel technologies using alginate composites are introduced, and as well as the latest developments in alginate-based technologies were reviewed. It also examines potential uses of alginates in immobilized biocatalysts, nanoparticle synthesis, wastewater treatment, heavy metal removal, agriculture, pharmaceuticals, and biomedicine.
Alginate is a hydrophilic, biocompatible, biodegradable, and relatively economical polymer generally found in marine brown algae. The modification in the alginate molecule after polymerization has shown strong potential in biomedical, pharmaceutical and biotechnology applications such as wound dressing, drug delivery, dental treatment, in cell culture and tissue engineering. Besides this, alginates have industrial applications too in the paper and food industries as plasticizers and additives. The few books that have been published on alginates focus more on their biology. This current book focuses on the exploration of alginates and their modification, characterization, derivatives, composites, hydrogels as well as the new and emerging applications.
Alginates and Their Biomedical Applications by Bernd H.A. Rehm,M. Fata Moradali Pdf
This book presents a comprehensive review of the latest advances in developing alginate-based biomaterials and derivatives as well as their biomedical and pharmaceutical applications. It covers the physiochemical properties of alginates, production and formulation methods, derivatizations and characterization methods, the fundamental work on optimizing alginate polymers for defined biomedical purposes as well as the scope and effectiveness of their applications in medicine and therapeutic approaches. The book brings together new concepts and advances in harnessing alginate-based biomaterials in combination with applied technological advances to tailor their applications to medical needs. The contributions by leading academics, clinicians and researchers not only cover the fundamentals, but also open new avenues for meeting future challenges in research and clinical applications.
Alginates by Manuel E. Molina,Andres J. Quiroga Pdf
Alginate is extracted from brown algae and some bacteria. It is an abundant natural polysaccharide and usually exists as sodium salt. In this book, the authors present topical research in the study of the production, types and applications of alginate. Topics discussed include the application of alginates in cell and enzyme immobilisation; alginate based materials in environmental applications; cross-linked alginates for modified drug delivery applications; bacterial alginate production by fermentation and the preparation and functionalisation of alginate-based hydrogels.
Alginates by Md Saquib Hasnain,Amit Kumar Nayak Pdf
This new volume explores the latest research on the use of alginate as a biopolymer in various biomedical applications and therapeutics. The uses of alginates and modified alginates discussed in this book include tissue regeneration, encapsulation and delivery of drugs, nucleic acid materials, proteins and peptides, genes, herbal therapeutic agents, nutraceuticals, and more. This book also describes the synthesis and characterizations of various alginate and modified alginate systems, such as hydrogels, gels, composites, nanoparticles, scaffolds, etc., used for the biomedical applications and therapeutics. Alginate, a biopolymer of natural origin, is of immense interest for its variety of applications in pharmaceuticals (as medical diagnostic aids) and in materials science. It is the one of the most abundant natural biopolymers and is considered an excellent excipient because of its non-toxic, stable, and biodegradable properties. Several research innovations have been made on applications of alginate in drug delivery and biomedicines. There needs to be a thorough understanding of the synthesis, purification, and characterization of alginates and its derivatives for their utility in healthcare fields, and this volume offers an abundance of information toward that end.
Industrial Applications of Marine Biopolymers by Parappurath Narayanan Sudha Pdf
Industrial Applications of Marine Biopolymers presents different classes of marine biopolymers and their industrial applications, demonstrating the precious value of ocean resources to society. This timely volume discusses the exceedingly useful polymers derived from these materials that are biodegradable, biocompatible, and at times water soluble. Direct use or chemically modified forms of such biomaterials have many chemical sites, making them suitable for varied types of industrial applications. In addition, this book also addresses current global challenges of conservation, including extended drought conditions and the need for improved agricultural methods, together with new bio-medical developments. It is suitable for anyone who has an interest in the industrial applications of biopolymers.
Alginate Biomaterial by Sougata Jana,Subrata Jana Pdf
This book focuses on recent trends of research on alginate-based biomaterials in Drug Delivery strategies and biomedical engineering. It contains the widely used alginate-based biomaterials as micro to nano-controlled drug delivery (oral, ocular delivery, topical delivery, etc.) and its fabrication technology, characterization, and biomedical aspects (such as cancer therapy, tissue engineering, gene delivery, vaccine delivery, enzyme immobilization, wound healing, dental applications, etc.) in a single book. The chapters cover updated information, current research trends, informatics, and all aspects of applications. Alginate is a U.S. Food and Drug Administration (FDA)-approved natural biomaterial and has diverse biomedical applications. In recent years, researchers and scientists are working on the alginate-based drug delivery systems that have been designed and characterized as a matrix, micro to nanocarriers, fibers, composite/scaffolds, etc. Alginate has versatile properties such as biodegradable, biocompatible, nontoxic, and easily available. This book especially highlights both the drug delivery strategies and biomedical engineering aspects such as controlled drug delivery, drug targeting to the site of action, cancer therapy, gene and vaccine delivery, enzyme immobilization, tissue engineering, and regenerative medicine.
Bioactive Seaweeds for Food Applications by Yimin Qin Pdf
Bioactive Seaweed Substances for Functional Food Applications: Natural Ingredients for Healthy Diets presents various types of bioactive seaweed substances and introduces their applications in functional food products. Presenting summaries of the substances derived from seaweed, this book systematically explores new ingredients and the bioactive substances that are both environmentally friendly and highly beneficial to human health. This evidence-based resource offers an abundance of information on the applications of seaweed as a solution to meet an increasing global demand for sustainable food sources. It is an essential reference for anyone involved in seaweed substance research, seaweed processing, and food and health disciplines. Discusses the use of bioactive seaweed substances as a new class of food ingredients Outlines the use of seaweed as gelling agents used for food restructuring, coating and encapsulation Systematically explores new ingredients and the bioactive substances that are both environmentally friendly and highly beneficial to human health
Alginate is a natural, anionic polysaccharide typically obtained from brown seaweed but it can be synthesized by some bacteria. It is a water-soluble, linear copolymer consisting of two kinds of alternating blocks, guluronic acid (G block) and mannuronic acid (M block) units, that are irregularly arranged in GG, MG, and MM blocks, while the ratio and pattern of guluronate to mannuronate blocks varies depending on the natural source of alginate. Most favorable properties of alginate are its biocompatibility, low toxicity, relatively low cost, and mild and easy gelation. Alginates in the presence of divalent cations (mostly calcium cations) very quickly form a hydrogel, polymeric networks with three-dimensional configuration, capable of imbibing high amounts of water. This book discusses the chemical structure, the uses, and health benefits of alginic acid.
Seaweed Polysaccharides by Jayachandran Venkatesan,Sukumaran Anil,Se-Kwon Kim Pdf
Seaweed Polysaccharides: Isolation, Biological, and Biomedical Applications examines the isolation and characterization of algal biopolymers, including a range of new biological and biomedical applications. In recent years, significant developments have been made in algae-based polymers (commonly called polysaccharides), and in biomedical applications such as drug delivery, wound dressings, and tissue engineering. Demand for algae-based polymers is increasing and represent a potential—very inexpensive—resource for these applications. The structure and chemical modification of algal polymers are covered, as well as the biological properties of these materials – including antithrombic, anti-inflammatory, anticoagulant, and antiviral aspects. Toxicity of algal biopolymers is also covered. Finally, the book introduces and explains real world applications of algal-based biopolymers in biomedical applications, including tissue engineering, drug delivery, and biosensors. This is the first book to cover the extraction techniques, biomedical applications, and the economic perspective of seaweed polysaccharides. It is an essential text for researchers and industry professionals looking to work with this renewable resource. Provides comprehensive coverage of the research currently taking place in biomedical applications of algae biopolymers Includes practical guidance on the isolation, extraction, and characterization of polysaccharides from sustainable marine sources Covers the extraction techniques, biomedical applications, and economic outlook of seaweed polysaccharides
Extracellular Sugar-Based Biopolymers Matrices by Ephraim Cohen,Hans Merzendorfer Pdf
The extracellular matrix (ECM) is an acellular three-dimensional network composed of proteins, glycoproteins, proteoglycans and exopolysaccharides. It primarily serves as a structural component in the tissues and organs of plants and animals, or forms biofilms in which bacterial cells are embedded. ECMs are highly dynamic structures that undergo continuous remodeling, and disruptions are frequently the result of pathological processes associated with severe diseases such as arteriosclerosis, neurodegenerative illness or cancer. In turn, bacterial biofilms are a source of concern for human health, as they are associated with resistance to antibiotics. Although exopolysaccharides are crucial for ECM formation and function, they have received considerably little attention to date. The respective chapters of this book comprehensively address such issues, and provide reviews on the structural, biochemical, molecular and biophysical properties of exopolysaccharides. These components are abundantly produced by virtually all taxa including bacteria, algae, plants, fungi, invertebrates and vertebrates. They include long unbranched homopolymers (cellulose, chitin/chitosan), linear copolymers (alginate, agarose), peptoglycans such as murein, heteropolymers like a variety of glycosaminoglycans (hyaluronan, dermatan, keratin, heparin, Pel), and branched heteropolymers such as pectin and hemicellulose. A separate chapter is dedicated to modern industrial and biomedical applications of exopolysaccharides and polysaccharide-based biocomposites. Their unique chemical, physical and mechanical properties have attracted considerable interest, inspired basic and applied research, and have already been harnessed to form structural biocomposite hybrids for tailor-made applications in regenerative medicine, bioengineering and biosensor design. Given its scope, this book provides a substantial source of basic and applied information for a wide range of scientists, as well as valuable textbook for graduate and advanced undergraduate students.
Alginates in Drug Delivery by Amit Kumar Nayak,Md Saquib Hasnain Pdf
Alginates in Drug Delivery explores the vital precepts, basic and fundamental aspects of alginates in pharmaceutical sciences, biopharmacology, and in the biotechnology industry. The use of natural polymers in healthcare applications over synthetic polymers is becoming more prevalent due to natural polymers’ biocompatibility, biodegradability, economic extraction and ready availability. To fully utilize and harness the potential of alginates, this book presents a thorough understanding of the synthesis, purification, and characterization of alginates and their derivative. This book collects, in a single volume, all relevant information on alginates in health care, including recent advances in the field. This is a highly useful resource for pharmaceutical scientists, health care professionals and regulatory scientists actively involved in the pharmaceutical product and process development of natural polymer containing drug delivery, as well as postgraduate students and postdoctoral research fellows in pharmaceutical sciences. Provides a single source on the complete alginate chemistry, collection, chemical modifications, characterization and applications in healthcare fields Includes high quality illustrations, along with practical examples and research case studies Contains contributions by global leaders and experts from academia, industry and regulatory agencies who are pioneers in the application of natural polysaccharides in diverse pharmaceutical fields
