All About Albumin

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All About Albumin

Author : Theodore Peters Jr.
Publisher : Academic Press
Page : 455 pages
File Size : 48,5 Mb
Release : 1995-12-21
Category : Science
ISBN : 9780080527048

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All About Albumin by Theodore Peters Jr. Pdf

The first of its kind, All About Albumin summarizes the chemistry, genetics, metabolism, clinical implications, and commercial aspects of albumin. It provides the most up-to-date sequences, structures, and compositions of many species, and includes more than 2000 references. Includes up-to-date sequences, structures, and compositions of many species Reviews the protein chemistry, genetic control, and metabolism of albumin Covers medical and cell culture applications in vivo and in vitro, with a section on handling albumin in the laboratory Presents the relationship of albumin to its superfamily with an updated scheme for their evolution First complete coverage of all aspects of serum albumin in one volume, with more than 2000 references

Albumin: Structure, Function and Uses

Author : Victor M. Rosenoer,Murray Oratz,Marcus A. Rothschild
Publisher : Elsevier
Page : 412 pages
File Size : 49,9 Mb
Release : 2014-05-18
Category : Medical
ISBN : 9781483156880

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Albumin: Structure, Function and Uses by Victor M. Rosenoer,Murray Oratz,Marcus A. Rothschild Pdf

Albumin Structure, Function and Uses reviews the many facets of serum albumin, including its history and evolutionary development, structure and function, synthesis, degradation, distribution and transport, and metabolic behavior. The use, misuse, and abuse of albumin in the treatment of disease are also discussed. This book is comprised of 17 chapters and begins with a commentary on how albumin is used, misused, and abused in the treatment of disease such as peptic ulcer, and a description of the real indications for its use. Concepts in albumin purification are then examined, along with the amino acid sequence of serum albumin and some aspects of its structure and conformational properties. Subsequent chapters explore the phylogenetics of albumin; albumin binding sites; clinical implications of drug-albumin interaction; genetics of human serum albumin; and hepatic synthesis of export proteins. Albumin catabolism and intracellular transport are also considered, together with surgical and clinical aspects of albumin metabolism. This monograph should be a useful resource for biochemists and clinicians.

Albumin in Medicine

Author : Masaki Otagiri,Victor Tuan Giam Chuang
Publisher : Springer
Page : 277 pages
File Size : 50,8 Mb
Release : 2016-11-01
Category : Medical
ISBN : 9789811021169

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Albumin in Medicine by Masaki Otagiri,Victor Tuan Giam Chuang Pdf

This book presents a comprehensive overview of medical and pharmaceutical applications of human serum albumin (HSA), with updates on structural aspects of albumin from the perspectives of X-ray crystallography and NMR, endogenous and exogenous ligand binding of albumin in various pathological conditions, and genetic variants and their phenotypes. Rapid progress and development of its applications have resulted in outstanding results for which albumin has clearly been proven to be a robust biomaterial. Contributions from leading international experts in this field show how HSA is applied to diagnosis, therapy, drugs, and treatment, with a comprehensive introduction of HSA. This volume will appeal to scientists in pharmaceutical and medical research including pharmaceutical chemists, pharmacokineticists, toxicologists, and biochemists not only in academia but also in industry. Readers can effectively acquire the most recent knowledge of applications of HSA and its impact on human health in a single volume.

Dioxygen Binding and Sensing Proteins

Author : Martino Bolognesi,Guido di Prisco,Cinzia Verde
Publisher : Springer Science & Business Media
Page : 259 pages
File Size : 53,9 Mb
Release : 2008-12-16
Category : Science
ISBN : 9788847008076

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Dioxygen Binding and Sensing Proteins by Martino Bolognesi,Guido di Prisco,Cinzia Verde Pdf

Following their own brilliant careers in haeme protein research, the outstanding scientists Jonathan and Beatrice Wittenberg continue to provide inspiration to the research community in the study of oxygen-binding proteins. Their research has provided the intellectual stimulus to bring together scientists from all over the world with the common goal of developing fascinating new ideas and performing innovative experiments. This book is dedicated to Jonathan’s and Bea’s lifetime careers. It further illuminates the facts and ideas which dot the paths they traced in Biochemistry and Physiology, elaborating on how these landmark achievements were made and how the haeme proteins community still refers to them. With the field of haeme protein science such a flourishing area, the contributors to this book predict Jonathan and Bea, having played such a seminal role, will continue to be key figures for quite some time to come.

The Plasma Proteins

Author : Frank W Putnam
Publisher : Elsevier
Page : 497 pages
File Size : 42,7 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323138086

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The Plasma Proteins by Frank W Putnam Pdf

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume I is a systematic account of the structure, function, and genetic control of plasma proteins. Clinical relevance is introduced in terms of principles, with emphasis on human proteins. Animal proteins are also used as examples in some cases. Comprised of nine chapters, this volume begins with a historical background on plasma proteins, along with their nomenclature, characterization, and genetic markers. The primary structure and three-dimensional conformation of plasma proteins are also considered. The discussion then turns to the chemical, physical, and biological properties of various plasma proteins such as serum albumin, lipoproteins, and immunoglobulins. Subsequent chapters deal with protease inhibitors in plasma; purification, physical properties, chemical composition, and molecular structure of transferrin; biosynthesis and metabolism of serum lipoproteins; and physical, chemical, and functional properties of the proteins of the complement system. The final chapter is devoted to ?2-microglobulin, with particular reference to its purification and physical properties; chemical composition and structure; physiological function, biosynthesis, and catabolism; and presence and function in cell membranes. This monograph will be of interest to molecular biologists and biochemists.

Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins

Author : Ulrich Hoeger,J. Robin Harris
Publisher : Springer Nature
Page : 527 pages
File Size : 47,8 Mb
Release : 2020-03-18
Category : Science
ISBN : 9783030417697

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Vertebrate and Invertebrate Respiratory Proteins, Lipoproteins and other Body Fluid Proteins by Ulrich Hoeger,J. Robin Harris Pdf

This book focuses on respiratory proteins, the broad hemoglobin family, as well as the molluscan and arachnid hemocyanins (and their multifunctional roles). Featuring 20 chapters addressing invertebrate and vertebrate respiratory proteins, lipoproteins and other body fluid proteins, and drawing on the editors’ extensive research in the field, it is a valuable addition to the Subcellular Biochemistry book series. The book covers a wide range of topics, including lipoprotein structure and lipid transport; diverse annelid, crustacean and insect defense proteins; and insect and vertebrate immune complexes. It also discusses a number of other proteins, such as the hemerythrins; serum albumin; serum amyloid A; von Willebrand factor and its interaction with factor VIII; and C-reactive protein. Given its scope, the book appeals to biologists, biomedical scientists and clinicians, as well as advanced undergraduates and postgraduates in these disciplines. Available as a printed book and also as an e-book and e-chapters, the fascinating material included is easily accessible.

Bovine Serum Albumin

Author : Martin A. Masuelli
Publisher : Unknown
Page : 220 pages
File Size : 55,6 Mb
Release : 2020-01-07
Category : Electronic
ISBN : 1536167878

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Bovine Serum Albumin by Martin A. Masuelli Pdf

Serum albumin is a large protein present in cow serum protein (BSA, Bovine Serum Albumin) rich in essential amino acids and compounds with disulfide bridges and thiol groups. This protein passes into breast milk from the bloodstream by diffusion, has antioxidant capacity and protects fats from oxidation. Albumin has the ability to inhibit tumor factors and bind to fat, mobilize them in the body to perform other functions such as obtaining energy or forming membranes. It is also able to block the conversion of angiotensin I into angiotensin II (vasoconstrictor) which gives it antihypertensive action. In addition, it has the ability to reduce cholesterol absorption, complex heavy metals and is an opioid agonist (acts on opioid receptors and promotes analgesia). BSA is the most studied and produced protein worldwide in the last 80 years. This protein brings large dividends to the world economy with a very prominent and favorable annual growth at a cost of 100 USD per gram. This book brings new contributions to the science and industry of this biopolymer. The audience of this book is very wide from students, teachers and researchers (doctors, pharmacists, biochemists and industrialists of this sector). Therefore, this book has a great future and many readers to whom it is addressed.

Biotechnology of Plasma Proteins

Author : Roger L. Lundblad
Publisher : CRC Press
Page : 460 pages
File Size : 53,6 Mb
Release : 2012-08-08
Category : Medical
ISBN : 9781439850275

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Biotechnology of Plasma Proteins by Roger L. Lundblad Pdf

The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to

Expanded Hemodialysis

Author : C. Ronco
Publisher : Karger Medical and Scientific Publishers
Page : 204 pages
File Size : 49,8 Mb
Release : 2017-09-14
Category : Medical
ISBN : 9783318061178

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Expanded Hemodialysis by C. Ronco Pdf

Despite constant significant advances, cardiovascular as well as more general outcomes of hemodialysis treatment remain unsatisfactory. The introduction of innovative 'high retention onset' membranes has led to the development of a new treatment modality called 'expanded hemodialysis' (HDx), which is the focus of this book. This new therapy is likely to benefit end-stage kidney disease patients, thanks to enhanced removal of molecules retained by current dialysis techniques. HDx is simple to set up and application does not require special hardware or specific nursing skills. This book contains emerging evidence and fascinating new hypotheses on HDx. It is highly recommended for all physicians and healthcare professionals who are caring for dialysis patients and are seeking innovation and improved care solutions. It will also be of considerable interest to students and fellows.

Serum Albumin

Author : Robert J. Alekseev,Alisa L. Rebane
Publisher : Unknown
Page : 0 pages
File Size : 44,5 Mb
Release : 2012
Category : Albumins
ISBN : 1621002314

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Serum Albumin by Robert J. Alekseev,Alisa L. Rebane Pdf

Serum albumin is the most abundant plasma protein in mammals. Albumin is essential for maintaining the osmotic pressure needed for proper distribution of body fluids between intravascular compartments and body tissues. It also acts as a plasma carrier by non-specifically binding several hydrophobic steroid hormones and as a transport protein for hemin and fatty acids. This book presents current research in the study of the structure, functions and health impacts of serum albumin. Topics include the catalytic activities of serum albumin; the interaction of serum albumin with anaesthetics; microparticulate drug delivery systems based on serum albumin; hydration of human serum albumin and extracting physical properties of serum albumin using osmotic pressure.

Clinical Methods

Author : Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst
Publisher : Butterworth-Heinemann
Page : 1128 pages
File Size : 40,9 Mb
Release : 1990
Category : Medical
ISBN : MINN:31951D00416688Z

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Clinical Methods by Henry Kenneth Walker,Wilbur Dallas Hall,John Willis Hurst Pdf

A guide to the techniques and analysis of clinical data. Each of the seventeen sections begins with a drawing and biographical sketch of a seminal contributor to the discipline. After an introduction and historical survey of clinical methods, the next fifteen sections are organized by body system. Each contains clinical data items from the history, physical examination, and laboratory investigations that are generally included in a comprehensive patient evaluation. Annotation copyrighted by Book News, Inc., Portland, OR

Clinical Aspects of Albumin

Author : S.H. Yap,C.L.H. Majoor,J.H.M. van Tongeren
Publisher : Springer Science & Business Media
Page : 214 pages
File Size : 55,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9789400997448

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Clinical Aspects of Albumin by S.H. Yap,C.L.H. Majoor,J.H.M. van Tongeren Pdf

Albumin is the most abundant serum protein produced by the liver. In clinical practice the serum level of albumin continues to be used as an important marker of the presence, progress or ofthe improvement of many diseases, even though it is the complex end result of synthesis, degradation a. nd distribution between intra- and extravascular space. The clinical history of albumin began as early as in 1837, when Ancell first recognized "albumen" and noted that this protein is needed for trans port functions, for maintaining fluidity of the vascular system and for the prevention of edema. However, the important physiological properties of serum proteins and their role in the regulation ofthe oncotic pressure were demonstrated later by the physiologist E. H. Starling in 1895. In 1917 the clinician A. A. Epstein first described the edema in patients with the nephro tic syndrome as being a result of a very low level of serum albumin. Al though the determination of serum albumin concentration became more popular after Howe in 1921 introduced the technique of separation of serum globulins from albumin by sodium sulfate, the first preparations of human serum albumin were made available for clinical use in only 1941 by the development of plasma fractionation by Cohn and his coworkers at Harvard Medical School.

Fundamentals of Protein Structure and Function

Author : Engelbert Buxbaum
Publisher : Springer
Page : 521 pages
File Size : 54,9 Mb
Release : 2015-11-27
Category : Science
ISBN : 9783319199207

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Fundamentals of Protein Structure and Function by Engelbert Buxbaum Pdf

This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. This leads to a discussion how misfolding of proteins causes diseases like cancer, various encephalopathies, or diabetes. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological and medical significance of this often neglected topic. This is followed by thorough coverage of hæmoglobin and myoglobin, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins to various cell compartments and solute transport across biological membranes. Proteins in the laboratory are also covered, including a detailed description of the purification and determination of proteins, as well as their characterisation for size and shape, structure and molecular interactions. The book emphasises the link between protein structure, physiological function and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine and related courses. About the author: Dr. Buxbaum is a biochemist with interest in enzymology and protein science. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities.

Human Blood Plasma Proteins

Author : Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel
Publisher : John Wiley & Sons
Page : 538 pages
File Size : 46,8 Mb
Release : 2008-05-23
Category : Science
ISBN : 0470724366

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Human Blood Plasma Proteins by Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel Pdf

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

The Plasma Proteins V3

Author : Frank Putnam
Publisher : Elsevier
Page : 630 pages
File Size : 48,9 Mb
Release : 2012-12-02
Category : Medical
ISBN : 9780323161466

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The Plasma Proteins V3 by Frank Putnam Pdf

The Plasma Proteins: Structure, Function, and Genetic Control, Second Edition, Volume III is an eight-chapter treatise that describes the plasma proteins in a systematic integrated manner. This book presents first the perspectives and global outlook at plasma proteins, followed by a series of chapters on the well-characterized major proteins, with particular emphasis on immunoglobulins. Other chapters are devoted to the integrated systems of plasma proteins, especially their structure, function, and genetic control. A chapter describes the plasma protein fractionation. The remaining chapters introduce the clinical relevance of the plasma proteins. This book will be of great value to biologists, geneticists, clinicians, and researchers.