Human Blood Plasma Proteins

Author : Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel
Publisher : John Wiley & Sons
Page : 538 pages
File Size : 42,6 Mb
Release : 2008-05-23
Category : Science
ISBN : 0470724366

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Human Blood Plasma Proteins by Johann Schaller,Simon Gerber,Urs Kaempfer,Sofia Lejon,Christian Trachsel Pdf

Human Blood Plasma Proteins gives an overview of the proteins found in human blood plasma, with special emphasis on their structure and function and relationship to pathological states and disease. Topics covered include: introduction to blood components and blood plasma proteins blood plasma protein domains, motifs and repeats blood plasma protein families and posttranslational modifications blood coagulation and fibrinolysis the complement system the immune system enzymes inhibitors lipoproteins hormones cytokines and growth factors transport and storage The information of each protein discussed in this book in some detail is summarised at the end of each chapter in a Data Sheet, where one can find the most important data of each protein at one glance. Full cross-referencing to protein databases is given and many of the proteins discussed are accompanied by their 3D structure. Attractively presented in full colour, Human Blood Plasma Proteins is an essential atlas of this proteome for anyone working in biochemistry, protein chemistry and proteomics, structural biology, and medicine.

Author : José Luis Valverde
Publisher : IOS Press
Page : 338 pages
File Size : 45,7 Mb
Release : 2006
Category : Business & Economics
ISBN : 1586036017

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Blood, Plasma, and Plasma Proteins by José Luis Valverde Pdf

Labile blood products and plasma-derived products are very sensitive form a social viewpoint. Along with the challenges faced by all medicinal products there is an added challenge due to the lack of raw material and the social problems with regards to their acquisition. Obtaining them depends on blood and plasma donations, which are insufficient. Europeans as a whole fail to even cover 40 % of their needs in plasma for fractionation. The aspiration that all donations shall be voluntary, free and unpaid, is an altruistic objective, which reality, unfortunately, contradicts every day. Governments and all social Agencies should promote to the maximum its actions in order to achieve the greatest number of donation each day. Even from a humanitarian or ethical viewpoint nobody can deny a possible donor accepting incentives. This incentive discussion, plus the concept of self-sufficiency of countries and more are discussed in this volume.

Author : James L. Tullis
Publisher : Elsevier
Page : 458 pages
File Size : 48,8 Mb
Release : 2013-10-22
Category : Medical
ISBN : 9781483261409

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Blood Cells and Plasma Proteins by James L. Tullis Pdf

Blood Cells and Plasma Proteins: Their State in Nature focuses on the properties, characteristics, reactions, and transformations of blood cells and plasma proteins. The selection first takes a look at the historical prologue on the discovery of the formed and fluid parts of human blood and chemical prologue on the characterization and separation of proteins by virtue of their interactions with neutral salts. The text then takes a look at interactions of proteins with each other and with heavy metals and interactions of proteins with alkaline earths, steroids, blood cells, and polysaccharides. The book then ponders on the components of human plasma concerned with coagulation and the biochemical, physiological, and pathological aspects of the coagulation mechanism. Discussions focus on evolution of the clotting mechanism, modern concepts of clotting, state of accelerator substances, and state of calcium. The text also tackles the nature of immune processes, antibodies in human gamma globulin, and physical characteristics of the gamma globulins. The selection is a valuable reference for readers interested in blood cells and plasma protein.

Author : J. W. Keyser
Publisher : Unknown
Page : 464 pages
File Size : 51,9 Mb
Release : 1987-12-28
Category : Medical
ISBN : UOM:39015012556463

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Human Plasma Proteins by J. W. Keyser Pdf

This review of the principal changes found in the plasma proteins in disease and often injury has been extensively revised and updated in the Second Editon. This book investigates a wide range of plasma proteins and their role in human diseases and disorders, including immunodeficiency, renal and liver disease, trauma, cancer, and neurological disease, among several others. This edition has been thoroughly updated and extensively revised. New material includes a chapter on the proteins associated with clotting abnormalities; sections on the latest methods for the detection of neural-tube defects in the fetus and for the pre- and post-natal diagnosis of cystic fibrosis; and appendixes on quality control, acrylamide gel electrophoresis of cerebrospinal fluid proteins, and the estimation of acetylcholinesterase in amniotic fluid. Includes illustrations and photos.

Author : C.Th. Smit Sibinga,P.C. Das,H.T. Meryman
Publisher : Springer Science & Business Media
Page : 297 pages
File Size : 53,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461315155

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Cryopreservation and low temperature biology in blood transfusion by C.Th. Smit Sibinga,P.C. Das,H.T. Meryman Pdf

The theme of this 14th International Symposium on Blood Transfusion is closely related to the work and scientific contributions of the Dutch cryobiology pioneer Dr. Herman W. Krijnen of the Dutch Red Cross Central Laboratory. Dr. Krijnen was known and respected in the national and interna tional blood transfusion community as an extremely competent scientist and a beloved and admired colleague. Dr. Krijnen was intentionally honoured with the invitation to open this symposium on cryopreservation and low temperature biology in blood transfusion and be the guest of honour at this event. Unfortunately, Dr. Krijnen suddenly died on the first of June 1989. In honour and mem ory of Dr. Krijnen this symposium will therefore be dedicated to him. Since the lOth International Symposium on Blood Transfusion in 1985 highlighted the theme of "Future developments in blood banking", major changes have occurred in the blood banking world. Most of these changes were forced upon the Blood Banks by the fear of spreading AIDS through contaminated donations. This not only led to the wide spread testing of blood, but also to a more appropriate counselling of the community and the blood donors in specific. Additionally, virus inacti vation techniques were introduced for those components derived from multiple donations and intended for a regular transfusion in haemophi lia patients and others.

Author : Ferdinand Wuhrmann,Charlie Wunderly
Publisher : Unknown
Page : 512 pages
File Size : 55,8 Mb
Release : 1960
Category : Blood
ISBN : UOM:39015003773762

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The Human Blood Proteins by Ferdinand Wuhrmann,Charlie Wunderly Pdf

Author : Joseph Bertolini,Neil Goss,John Curling
Publisher : John Wiley & Sons
Page : 518 pages
File Size : 46,9 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9780470924310

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Production of Plasma Proteins for Therapeutic Use by Joseph Bertolini,Neil Goss,John Curling Pdf

Sets forth the state of the science and technology in plasma protein production With contributions from an international team of eighty leading experts and pioneers in the field, Production of Plasma Proteins for Therapeutic Use presents a comprehensive overview of the current state of knowledge about the function, use, and production of blood plasma proteins. In addition to details of the operational requirements for the production of plasma derivatives, the book describes the biology, development, research, manufacture, and clinical indications of essentially all plasma proteins with established clinical use or therapeutic potential. Production of Plasma Proteins for Therapeutic Use covers the key aspects of the plasma fractionation industry in five sections: Section 1: Introduction to Plasma Fractionation initially describes the history of transfusion and then covers the emergence of plasma collection and fractionation from its earliest days to the present time, with the commercial and not-for-profit sectors developing into a multi-billion dollar industry. Section 2: Plasma Proteins for Therapeutic Use contains 24 chapters dedicated to specific plasma proteins, including coagulation factors, albumin, immunoglobulin, and a comprehensive range of other plasma-derived proteins with therapeutic indications. Each chapter discusses the physiology, biochemistry, mechanism of action, and manufacture of each plasma protein including viral safety issues and clinical uses. Section 3: Pathogen Safety of Plasma Products examines issues and procedures for enhancing viral safety and reducing the risk of transmissible spongiform encephalopathy transmission. Section 4: The Pharmaceutical Environment Applied to Plasma Fractionation details the requirements and activities associated with plasma collection, quality assurance, compliance with regulatory requirements, provision of medical affairs support, and the manufacture of plasma products. Section 5: The Market for Plasma Products and the Economics of Fractionation reviews the commercial environment and economics of the plasma fractionation industry including future trends, highlighting regions such as Asia, which have the potential to exert a major influence on the plasma fractionation industry in the twenty-first century.

Author : Roger L. Lundblad
Publisher : CRC Press
Page : 460 pages
File Size : 41,8 Mb
Release : 2012-08-08
Category : Medical
ISBN : 9781439850275

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Biotechnology of Plasma Proteins by Roger L. Lundblad Pdf

The fractionation of human blood plasma can be considered to be a mature industry, with the basic technology, alcohol fractionation, dating back at least to the 1940s. Many of the products described in the current work have been approved biologics since the 1950s. The information gathered from the development of plasma proteins has proved vital to

Author : James William Kaiser
Publisher : Unknown
Page : 330 pages
File Size : 44,9 Mb
Release : 1979-01-01
Category : Electronic
ISBN : 0608155721

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Human Plasma Proteins by James William Kaiser Pdf

Author : A. Allison
Publisher : Springer Science & Business Media
Page : 434 pages
File Size : 49,7 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781468426793

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Structure and Function of Plasma Proteins by A. Allison Pdf

1 Ontogeny of Human Plasma Proteins: Detection of the Onset and Site of Synthesis Using Genetic Markers and in Vitro Cultures.- 1.1. Introduction.- 1.2. Immunoglobulins.- 1.2.1. Classes and Subclasses and Genetic Markers.- 1.2.2. Synthesis of Ig Molecules at Cellular Level.- 1.2.3. Transfer of Immunoglobulins through the Placenta.- 1.2.4. Synthesis of Immunoglobulins during Fetal Life.- 1.3. Complement.- 1.3.1. The Components of Complement.- 1.3.2. Levels and Fetal Synthesis of the Components of C.- 1.4. Haptoglobin System.- 1.5. Transferrins.- 1.6. ?-Lipoprotein Variants: The Ag and Lp System.

Author : James W. Keyser
Publisher : Unknown
Page : 451 pages
File Size : 52,8 Mb
Release : 1987-01-01
Category : Electronic
ISBN : 0783782640

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Human Plasma Proteins by James W. Keyser Pdf

Author : Barbara H. Bowman
Publisher : Elsevier
Page : 298 pages
File Size : 42,5 Mb
Release : 2014-05-10
Category : Medical
ISBN : 9781483216508

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Hepatic Plasma Proteins by Barbara H. Bowman Pdf

Hepatic Plasma Proteins: Mechanisms of Function and Regulation covers the mechanisms of function, inherited variation, and regulation of genes encoding the plasma proteins synthesized in the liver. The book discusses the physiological and clinical implications of human plasma protein abnormalities; the acute-phase reactants; and the variety of human plasma proteinase inhibitors. The text also describes the plasma protein vehicles (transferrin, ceruloplasmin, transthyretin, haptoglobin, hemopexin, and the vitamin D binding protein), as well as cytokines and transcription factors involved in the regulatory process. The protein and gene anatomies are discussed in terms of evolutionary relationships and genetic variations, especially those with mutations causing clinical manifestations. The book also encompasses the mechanisms responsible for tissue specific and developmental expression of plasma protein genes. Geneticists, biochemists, molecular biologists, physicians, and other students of biology will find the book invaluable.

Author : Frank W. Putnam
Publisher : Unknown
Page : 438 pages
File Size : 54,9 Mb
Release : 1975
Category : Medical
ISBN : 0125684045

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The Plasma Proteins by Frank W. Putnam Pdf

The Plasma Proteins V4 ...

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 47,9 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Frank Putnam
Publisher : Elsevier
Page : 534 pages
File Size : 49,5 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323146821

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The Plasma Proteins by Frank Putnam Pdf

The Plasma Proteins, Volume II: Biosynthesis, Metabolism, Alternations in Disease is a 10-chapter text that explores the physiological role and metabolic interrelationships of the human plasma proteins in the normal state and in disease. The first two chapters cover the physical properties, chemical composition, function, methods of analysis of human serum lipoproteins and plasma enzymes. The subsequent chapter considers the normal levels of hormones in plasma or serum and their distribution in the plasma protein fractions. These topics are followed by discussions on the blood coagulation system, the serum proteins in the animal kingdom at maturity and during embryonic development, and the biosynthesis of plasma proteins. The remaining chapters examine the qualitative abnormalities in various plasma proteins. These chapters also discuss the modification in plasma protein synthesis induced by genetic variation. Such alterations are described for albumin, ceruloplasmin, haptoglobin, iron-binding globulin, fibrinogen, antihemophilic globulin, and other blood clotting factors, as well as γ-globulin. Biochemists, physiologists, and medical researchers will find this book invaluable.