American Overdose

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American Overdose

Chris McGreal
American Overdose Book PDF

Author : Chris McGreal
Publisher : PublicAffairs
Page : 381 pages
File Size : 48,8 Mb
Release : 2018-11-13
Category : Social Science
ISBN : 9781541773776

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American Overdose by Chris McGreal Pdf

A comprehensive portrait of a uniquely American epidemic -- devastating in its findings and damning in its conclusions The opioid epidemic has been described as "one of the greatest mistakes of modern medicine." But calling it a mistake is a generous rewriting of the history of greed, corruption, and indifference that pushed the US into consuming more than 80 percent of the world's opioid painkillers. Journeying through lives and communities wrecked by the epidemic, Chris McGreal reveals not only how Big Pharma hooked Americans on powerfully addictive drugs, but the corrupting of medicine and public institutions that let the opioid makers get away with it. The starting point for McGreal's deeply reported investigation is the miners promised that opioid painkillers would restore their wrecked bodies, but who became targets of "drug dealers in white coats." A few heroic physicians warned of impending disaster. But American Overdose exposes the powerful forces they were up against, including the pharmaceutical industry's coopting of the Food and Drug Administration and Congress in the drive to push painkillers -- resulting in the resurgence of heroin cartels in the American heartland. McGreal tells the story, in terms both broad and intimate, of people hit by a catastrophe they never saw coming. Years in the making, its ruinous consequences will stretch years into the future.

American Overdose

Chris McGreal
American Overdose Book PDF

Author : Chris McGreal
Publisher : Faber & Faber
Page : 320 pages
File Size : 44,6 Mb
Release : 2018-11-13
Category : True Crime
ISBN : 9781783351701

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American Overdose by Chris McGreal Pdf

*LONGLISTED FOR THE ORWELL PRIZE FOR POLITICAL WRITING 2019* 'A riveting and urgent reckoning of colossal corruption.' - Philip Gourevitch One hundred and fifty Americans are killed each day by the opioid epidemic, described by a former head of the Food and Drug Administration as 'one of the greatest mistakes of modern medicine'. But as Chris McGreal reveals in American Overdose, it was an avoidable tragedy driven by bad science, corporate greed and a corrupted medical system. In a narrative brimming with the guilty, the victims and the unlikely heroes, Chris McGreal travels from West Virginia 'pill mills' to the corridors of Washington DC as he unravels the story of Big Pharma's hijacking of American healthcare and politics to push mass prescribing of 'heroin in a pill'. He meets the police and FBI agents who struggled to get prosecutors to go after doctors they called 'drug dealers in white coats'; the families devastated by painkillers they thought would heal, not kill; and the physicians and scientists who took on the drug companies behind the epidemic. The result is an immensely powerful account of the terrible human cost of the crisis, and a stark warning of the consequences of a healthcare system run as a business, not a service.

Pain Management and the Opioid Epidemic

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Pain Management and the Opioid Epidemic Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publisher : National Academies Press
Page : 483 pages
File Size : 45,5 Mb
Release : 2017-09-28
Category : Medical
ISBN : 9780309459570

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Pain Management and the Opioid Epidemic by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse Pdf

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Overdosed America

John Abramson
Overdosed America Book PDF

Author : John Abramson
Publisher : Harper Collins
Page : 362 pages
File Size : 41,9 Mb
Release : 2005-06-14
Category : Business & Economics
ISBN : 9780060568535

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Overdosed America by John Abramson Pdf

Using the examples of Vioxx, Celebrex, cholesterol-lowering statin drugs, and anti-depressants, Overdo$ed America shows that at the heart of the current crisis in American medicine lies the commercialization of medical knowledge itself. Drawing on his background in statistics, epidemiology, and health policy, John Abramson, M.D., an award-winning family doctor on the clinical faculty at Harvard Medical School, reveals the ways in which the drug companies have misrepresented statistical evidence, misled doctors, and compromised our health. The good news is that the best scientific evidence shows that reclaiming responsibility for your own health is often far more effective than taking the latest blockbuster drug. You -- and your doctor -- will be stunned by this unflinching exposé of American medicine.

Medications for Opioid Use Disorder Save Lives

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
Medications for Opioid Use Disorder Save Lives Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder
Publisher : National Academies Press
Page : 175 pages
File Size : 43,5 Mb
Release : 2019-06-16
Category : Medical
ISBN : 9780309486484

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Medications for Opioid Use Disorder Save Lives by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Medication-Assisted Treatment for Opioid Use Disorder Pdf

The opioid crisis in the United States has come about because of excessive use of these drugs for both legal and illicit purposes and unprecedented levels of consequent opioid use disorder (OUD). More than 2 million people in the United States are estimated to have OUD, which is caused by prolonged use of prescription opioids, heroin, or other illicit opioids. OUD is a life-threatening condition associated with a 20-fold greater risk of early death due to overdose, infectious diseases, trauma, and suicide. Mortality related to OUD continues to escalate as this public health crisis gathers momentum across the country, with opioid overdoses killing more than 47,000 people in 2017 in the United States. Efforts to date have made no real headway in stemming this crisis, in large part because tools that already existâ€"like evidence-based medicationsâ€"are not being deployed to maximum impact. To support the dissemination of accurate patient-focused information about treatments for addiction, and to help provide scientific solutions to the current opioid crisis, this report studies the evidence base on medication assisted treatment (MAT) for OUD. It examines available evidence on the range of parameters and circumstances in which MAT can be effectively delivered and identifies additional research needed.

Addiction and Overdose

Connie Goldsmith
Addiction and Overdose Book PDF

Author : Connie Goldsmith
Publisher : Twenty-First Century Books
Page : 132 pages
File Size : 55,7 Mb
Release : 2017
Category : Young Adult Nonfiction
ISBN : 9781512409536

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Addiction and Overdose by Connie Goldsmith Pdf

An exploration of drug addiction in the United States.

Raising Lazarus

Beth Macy
Raising Lazarus Book PDF

Author : Beth Macy
Publisher : Little, Brown
Page : 427 pages
File Size : 44,8 Mb
Release : 2022-08-16
Category : Business & Economics
ISBN : 9780316430203

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Raising Lazarus by Beth Macy Pdf

A “deeply reported, deeply moving” (Patrick Radden Keefe) account of everyday heroes fighting on the front lines of the overdose crisis, from the New York Times bestselling author of Dopesick (inspiration for the Peabody Award-winning Hulu limited series) and Factory Man. Nearly a decade into the second wave of America's overdose crisis, pharmaceutical companies have yet to answer for the harms they created. As pending court battles against opioid makers, distributors, and retailers drag on, addiction rates have soared to record-breaking levels during the COVID pandemic, illustrating the critical need for leadership, urgency, and change. Meanwhile, there is scant consensus between law enforcement and medical leaders, nor an understanding of how to truly scale the programs that are out there, working at the ragged edge of capacity and actually saving lives. Distilling this massive, unprecedented national health crisis down to its character-driven emotional core as only she can, Beth Macy takes us into the country’s hardest hit places to witness the devastating personal costs that one-third of America's families are now being forced to shoulder. Here we meet the ordinary people fighting for the least of us with the fewest resources, from harm reductionists risking arrest to bring lifesaving care to the homeless and addicted to the activists and bereaved families pushing to hold Purdue and the Sackler family accountable. These heroes come from all walks of life; what they have in common is an up-close and personal understanding of addiction that refuses to stigmatize—and therefore abandon—people who use drugs, as big pharma execs and many politicians are all too ready to do. Like the treatment innovators she profiles, Beth Macy meets the opioid crisis where it is—not where we think it should be or wish it was. Bearing witness with clear eyes, intrepid curiosity, and unfailing empathy, she brings us the crucial next installment in the story of the defining disaster of our era, one that touches every single one of us, whether directly or indirectly. A complex story of public health, big pharma, dark money, politics, race, and class that is by turns harrowing and heartening, infuriating and inspiring, Raising Lazarus is a must-read for all Americans.

Pain Killer

Barry Meier
Pain Killer Book PDF

Author : Barry Meier
Publisher : Random House
Page : 241 pages
File Size : 44,7 Mb
Release : 2018-05-29
Category : Medical
ISBN : 9780525511090

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Pain Killer by Barry Meier Pdf

From the Pulitzer Prize–winning New York Times reporter who first exposed the roots of the opioid epidemic and the secretive world of the Sackler family behind Purdue Pharma, Pain Killer is the celebrated landmark story of corporate greed and government negligence that inspired an upcoming Netflix series. “This is the book that started it all. Barry Meier is a heroic reporter and Pain Killer is a muckraking classic.”—Patrick Radden Keefe, author of Empire of Pain Between 1999 and 2017, an estimated 250,000 Americans died from overdoses involving prescription painkillers, a plague ignited by Purdue Pharma’s aggressive marketing of OxyContin. Families, working class and wealthy, have been torn apart, businesses destroyed, and public officials pushed to the brink. Meanwhile, the drugmaker’s owners, Raymond and Mortimer Sackler, whose names adorn museums worldwide, made enormous fortunes from the commercial success of OxyContin. In Pain Killer, Barry Meier tells the story of how Purdue turned OxyContin into a billion-dollar blockbuster. Powerful narcotic painkillers, or opioids, were once used as drugs of last resort for pain sufferers. But Purdue launched an unprecedented marketing campaign claiming that the drug’s long-acting formulation made it safer to use than traditional painkillers for many types of pain. That illusion was quickly shattered as drug abusers learned that crushing an Oxy could release its narcotic payload all at once. Even in its prescribed form, Oxy proved fiercely addictive. As OxyContin’s use and abuse grew, Purdue concealed what it knew from regulators, doctors, and patients. Here are the people who profited from the crisis and those who paid the price, those who plotted in boardrooms and those who tried to sound alarm bells. A country doctor in rural Virginia, Art Van Zee, took on Purdue and warned officials about OxyContin abuse. An ebullient high school cheerleader, Lindsey Myers, was reduced to stealing from her parents to feed her escalating Oxy habit. A hard-charging DEA official, Laura Nagel, tried to hold Purdue executives to account. In Pain Killer, Barry Meier breaks new ground in his decades-long investigation into the opioid epidemic. He takes readers inside Purdue to show how long the company withheld information about the abuse of OxyContin and gives a shocking account of the Justice Department’s failure to alter the trajectory of the opioid epidemic and protect thousands of lives. Equal parts crime thriller, medical detective story, and business exposé, Pain Killer is a hard-hitting look at how a supposed wonder drug became the gateway drug to a national tragedy.

Unsettled

Ryan Hampton
Unsettled Book PDF

Author : Ryan Hampton
Publisher : St. Martin's Press
Page : 249 pages
File Size : 52,9 Mb
Release : 2021-10-05
Category : Political Science
ISBN : 9781250273178

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Unsettled by Ryan Hampton Pdf

A shocking inside account of reckless capitalism and injustice in the Purdue Pharma bankruptcy case. In September 2019, Purdue Pharma—the maker of OxyContin and a company controlled by the infamous billionaire Sackler family—filed for bankruptcy to protect itself from 2,600 lawsuits for its role in fueling the U.S. overdose crisis. Author and activist Ryan Hampton served as co-chair of the official creditors committee that acted as a watchdog during the process, one of only four victims appointed among representatives of big insurance companies, hospitals, and pharmacies. He entered the case believing that exposing the Sacklers and mobilizing against Purdue would be enough to right the scales of justice. But he soon learned that behind closed doors, justice had plenty of other competition—and it came with a hefty price tag. Unsettled is the inside story of Purdue’s excruciating Chapter 11 bankruptcy proceedings, the company’s eventual restructuring, and the Sackler family’s evasion of any true accountability. It’s also the untold story of how a group of determined ordinary people tried to see justice done against the odds—and in the face of brutal opposition from powerful institutions and even government representatives. Although America was envisioned as an equitable place, where the vulnerable are protected from the greed of the powerful, the corporate-bankruptcy process betrays those values. In its heart of hearts, this system is built to shield the ultra-wealthy, exploit loopholes for political power, promote gross wealth inequality, and allow companies such as Purdue Pharma to run amok. The real story of the Purdue bankruptcy wasn’t that the billion-dollar corporation was a villain, a serial federal offender. No matter what the media said, Purdue didn’t do this alone. They were aided and abetted by the very systems and institutions that were supposed to protect Americans. Even on-your-side elected officials worked against Purdue’s victims—maintaining the status quo at all costs. Americans deserve to know exactly who is responsible for failing to protect people over profits—and what a human life is worth to corporations, billionaires, and lawmakers. Unsettled is what happened behind closed doors—the story of a sick, broken system that destroyed millions of lives and let the Sacklers off almost scot-free.

The American Opioid Epidemic

Michael T. Compton, M.D., M.P.H.,Marc W. Manseau, M.D., M.P.H.
The American Opioid Epidemic Book PDF

Author : Michael T. Compton, M.D., M.P.H.,Marc W. Manseau, M.D., M.P.H.
Publisher : American Psychiatric Pub
Page : 462 pages
File Size : 49,5 Mb
Release : 2018-12-31
Category : Medical
ISBN : 9781615371570

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The American Opioid Epidemic by Michael T. Compton, M.D., M.P.H.,Marc W. Manseau, M.D., M.P.H. Pdf

This book provides an in-depth look at clinical and public health approaches to this epidemic from both psychiatric and medical perspectives and gives mental health professionals the big picture necessary to understand the epidemic.

Dreamland (YA edition)

Sam Quinones
Dreamland YA edition Book PDF

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
Page : 225 pages
File Size : 45,7 Mb
Release : 2019-07-16
Category : Juvenile Nonfiction
ISBN : 9781547601417

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Dreamland (YA edition) by Sam Quinones Pdf

As an adult book, Sam Quinones's Dreamland took the world by storm, winning the NBCC Award for General Nonfiction and hitting at least a dozen Best Book of the Year lists. Now, adapted for the first time for a young adult audience, this compelling reporting explains the roots of the current opiate crisis. In 1929, in the blue-collar city of Portsmouth, Ohio, a company built a swimming pool the size of a football field; named Dreamland, it became the vital center of the community. Now, addiction has devastated Portsmouth, as it has hundreds of small rural towns and suburbs across America. How that happened is the riveting story of Dreamland. Quinones explains how the rise of the prescription drug OxyContin, a miraculous and extremely addictive painkiller pushed by pharmaceutical companies, paralleled the massive influx of black tar heroin--cheap, potent, and originating from one small county on Mexico's west coast, independent of any drug cartel. Introducing a memorable cast of characters--pharmaceutical pioneers, young Mexican entrepreneurs, narcotics investigators, survivors, teens, and parents--Dreamland is a revelatory account of the massive threat facing America and its heartland.

Deaths of Despair and the Future of Capitalism

Anne Case,Angus Deaton
Deaths of Despair and the Future of Capitalism Book PDF

Author : Anne Case,Angus Deaton
Publisher : Princeton University Press
Page : 332 pages
File Size : 52,8 Mb
Release : 2021-03-02
Category : Business & Economics
ISBN : 9780691217062

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Deaths of Despair and the Future of Capitalism by Anne Case,Angus Deaton Pdf

A New York Times Bestseller A Wall Street Journal Bestseller A New York Times Notable Book of 2020 A New York Times Book Review Editors’ Choice Shortlisted for the Financial Times and McKinsey Business Book of the Year A New Statesman Book to Read From economist Anne Case and Nobel Prize winner Angus Deaton, a groundbreaking account of how the flaws in capitalism are fatal for America's working class Deaths of despair from suicide, drug overdose, and alcoholism are rising dramatically in the United States, claiming hundreds of thousands of American lives. Anne Case and Angus Deaton explain the overwhelming surge in these deaths and shed light on the social and economic forces that are making life harder for the working class. As the college educated become healthier and wealthier, adults without a degree are literally dying from pain and despair. Case and Deaton tie the crisis to the weakening position of labor, the growing power of corporations, and a rapacious health-care sector that redistributes working-class wages into the pockets of the wealthy. This critically important book paints a troubling portrait of the American dream in decline, and provides solutions that can rein in capitalism's excesses and make it work for everyone.

The Health Effects of Cannabis and Cannabinoids

National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
The Health Effects of Cannabis and Cannabinoids Book PDF

Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publisher : National Academies Press
Page : 487 pages
File Size : 43,9 Mb
Release : 2017-03-31
Category : Science
ISBN : 9780309453073

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The Health Effects of Cannabis and Cannabinoids by National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda Pdf

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

The Least of Us

Sam Quinones
The Least of Us Book PDF

Author : Sam Quinones
Publisher : Bloomsbury Publishing USA
Page : 433 pages
File Size : 49,5 Mb
Release : 2021-11-02
Category : Social Science
ISBN : 9781635574371

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The Least of Us by Sam Quinones Pdf

Apple Best Books of 2021 Longlisted for the Andrew Carnegie Medal * Shortlisted for the Zocalo Book Prize From the New York Times bestselling author of Dreamland, a searing follow-up that explores the terrifying next stages of the opioid epidemic and the quiet yet ardent stories of community repair. Sam Quinones traveled from Mexico to main streets across the U.S. to create Dreamland, a groundbreaking portrait of the opioid epidemic that awakened the nation. As the nation struggled to put back the pieces, Quinones was among the first to see the dangers that lay ahead: synthetic drugs and a new generation of kingpins whose product could be made in Magic Bullet blenders. In fentanyl, traffickers landed a painkiller a hundred times more powerful than morphine. They laced it into cocaine, meth, and counterfeit pills to cause tens of thousands of deaths-at the same time as Mexican traffickers made methamphetamine cheaper and more potent than ever, creating, Sam argues, swaths of mental illness and a surge in homelessness across the United States. Quinones hit the road to investigate these new threats, discovering how addiction is exacerbated by consumer-product corporations. “In a time when drug traffickers act like corporations and corporations like traffickers,” he writes, “our best defense, perhaps our only defense, lies in bolstering community.” Amid a landscape of despair, Quinones found hope in those embracing the forgotten and ignored, illuminating the striking truth that we are only as strong as our most vulnerable. Weaving analysis of the drug trade into stories of humble communities, The Least of Us delivers an unexpected and awe-inspiring response to the call that shocked the nation in Sam Quinones's award-winning Dreamland.

Dopesick

Beth Macy
Dopesick Book PDF

Author : Beth Macy
Publisher : Bloomsbury Publishing
Page : 495 pages
File Size : 42,5 Mb
Release : 2018-08-09
Category : Psychology
ISBN : 9781788549363

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Dopesick by Beth Macy Pdf

Now a major TV series on Disney+ 'A shocking investigation... Dopesick is essential' The Times 'Unfolds with all the pace of a thriller' Observer 'A deep – and deeply needed – look into the troubled soul of America' Tom Hanks 'Essential reading' New York Times Beth Macy reveals the disturbing truth behind America's opioid crisis and explains how a nation has become enslaved to prescription drugs. This powerful and moving story explains how a large corporation, Purdue, encouraged small town doctors to prescribe OxyContin to a country already awash in painkillers. The drug's dangerously addictive nature was hidden, whilst many used it as an escape, to numb the pain of of joblessness and the need to pay the bills. Macy tries to answer a grieving mother's question – why her only son died – and comes away with a harrowing tale of greed and need.