Amyloid Prions And Other Protein Aggregates Part C

Author : Anonim
Publisher : Elsevier
Page : 412 pages
File Size : 53,8 Mb
Release : 2006-10-06
Category : Science
ISBN : 9780080468976

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Amyloid, Prions, and Other Protein Aggregates, Part C by Anonim Pdf

The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part B (volume 412) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. Presents detailed protocols Includes troubleshooting tips Provides coverage on structural biology, computational methods, and biology

Author : Anonim
Publisher : Elsevier
Page : 430 pages
File Size : 46,5 Mb
Release : 2006-10-06
Category : Science
ISBN : 0080522548

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Amyloid, Prions, and Other Protein Aggregates by Anonim Pdf

The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. Presents detailed protocols Includes troubleshooting tips Provides coverage on structural biology, computational methods, and biology

Author : Anonim
Publisher : Unknown
Page : 403 pages
File Size : 41,5 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:475267970

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Methods in Enzymology by Anonim Pdf

Author : Anonim
Publisher : Academic Press
Page : 0 pages
File Size : 55,9 Mb
Release : 2006-10-06
Category : Science
ISBN : 0121828174

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Amyloid, Prions, and Other Protein Aggregates, Part B by Anonim Pdf

The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies.

Author : Ronald Wetzel
Publisher : Unknown
Page : 878 pages
File Size : 55,8 Mb
Release : 1999
Category : Aggregation (Chemistry)
ISBN : UVA:X004346896

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Amyloid, Prions, and Other Protein Aggregates by Ronald Wetzel Pdf

Characterization of in vivo protein deposition Characterization of in vitro protein deposition Aggregate and precursor protein structure Cellular and organismic consequences of protein deposition.

Author : Anonim
Publisher : Unknown
Page : 128 pages
File Size : 45,6 Mb
Release : 2006
Category : Electronic
ISBN : OCLC:760560983

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Amyloid, Prions, and Other Protein Aggregates, Part C. by Anonim Pdf

Author : John M. Squire,David A.D. Parry,Andrey Kajava
Publisher : Elsevier
Page : 329 pages
File Size : 44,8 Mb
Release : 2006-12-12
Category : Science
ISBN : 9780080468952

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Fibrous Proteins: Amyloids, Prions and Beta Proteins by John M. Squire,David A.D. Parry,Andrey Kajava Pdf

Amyloids, Prions and Beta Proteins is the last volume of the three-part thematic series on Fibrous Proteins in the Advances in Protein Chemistry serial. Fibrous proteins act as molecular scaffolds in cells providing the supporting structures of our skeletons, bones, tendons, cartilage, and skin. They define the mechanical properties of our internal hollow organs such as the intestines, heart, and blood vessels. This volume covers such topics as Beta-Structures in Fibrous Proteins; B-Silks: Enhancing and Controlling Aggregation; Beta-Rolls, Beta-Helices and Other Beta-Solenoid Proteins; Natural Triple B-Stranded Fibrous Folds; Structure, Function and Amyloidogenesis of Fungal Prions: Filament Polymorphism and Prion Variants; X-Ray Fiber and powder Diffraction of PRP Prion Peptides; From the Polymorphism of Amyloid Fibrils to Their Assembly Mechanism and Cytotoxicity; Structural Models of Amyloid-like Fibrils.

Author : Anonim
Publisher : Academic Press
Page : 430 pages
File Size : 43,8 Mb
Release : 2006-10-20
Category : Science
ISBN : 0121828174

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Amyloid, Prions, and Other Protein Aggregates by Anonim Pdf

The ability of polypeptides to form alternatively folded, polymeric structures such as amyloids and related aggregates is being increasingly recognized as a major new frontier in protein research. This new volume of Methods in Enzymology along with Part C (volume 413) on Amyloid, Prions and other Protein Aggregates continue in the tradition of the first volume (309) in containing detailed protocols and methodological insights, provided by leaders in the field, into the latest methods for investigating the structures, mechanisms of formation, and biological activities of this important class of protein assemblies. Presents detailed protocols Includes troubleshooting tips Provides coverage on structural biology, computational methods, and biology

Author : Daniel Erik Otzen
Publisher : John Wiley & Sons
Page : 496 pages
File Size : 49,8 Mb
Release : 2013-06-04
Category : Science
ISBN : 9783527654208

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Amyloid Fibrils and Prefibrillar Aggregates by Daniel Erik Otzen Pdf

Summing up almost a decade of biomedical research, this topical and eagerly awaited handbook is the first reference on the topic to incorporate recent breakthroughs in amyloid research. The first part covers the structural biology of amyloid fibrils and pre-fibrillar assemblies, including a description of current models for amyloid formation. The second part looks at the diagnosis and biomedical study of amyloid in humans and in animal models, while the final section discusses pharmacological approaches to manipulating amyloid and also looks at its physiological roles in lower and higher organisms. For Biochemists, Molecular Biologists, Neurobiologists, Neurophysiologists and those working in the Pharmaceutical Industry.

Author : Anonim
Publisher : Academic Press
Page : 320 pages
File Size : 52,5 Mb
Release : 2017-02-01
Category : Science
ISBN : 9780128122525

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Early Stage Protein Misfolding and Amyloid Aggregation by Anonim Pdf

Early Stage Protein Misfolding and Amyloid Aggregation, Volume 329, the latest in the International Review of Cell and Molecular Biology series presents comprehensive reviews and current advances in cell and molecular biology, including articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership and maintains a high standard by publishing invited articles on important and timely topics as authored by prominent cell and molecular biologists. Provides comprehensive reviews and current advances Presents a wide range of perspectives on specific subjects Includes valuable reference material for advanced undergraduates, graduate students, and professional scientists

Author : J. Robin Harris
Publisher : Springer Science & Business Media
Page : 654 pages
File Size : 50,6 Mb
Release : 2012-12-09
Category : Medical
ISBN : 9789400754164

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Protein Aggregation and Fibrillogenesis in Cerebral and Systemic Amyloid Disease by J. Robin Harris Pdf

This volume of the Subcellular Biochemistry series is the result of the long-standing research interest of the editor in the molecular mechanism underlying Alzheimer’s disease and other amyloid diseases, indicated also by the earlier book in the series (Volume 38), devoted to Alzheimer’s disease. The broad coverage within the present amyloidogenesis book represents an attempt to collate current knowledge relating to the proteins and peptides involved in most of the known amyloid diseases, together with some amyloid/fibril-forming proteins and peptides that are not involved in diseases. Thus, the range of topics included is comprehensive and furthermore it was thought appropriate to include both basic science and clinical presentation of the subjects under discussion.

Author : Anonim
Publisher : Academic Press
Page : 820 pages
File Size : 46,8 Mb
Release : 1999-09-28
Category : Science
ISBN : 0121822109

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Amyloid, Prions, and Other Protein Aggregates by Anonim Pdf

This volume includes a core of methodologies to attack the unique experimental problems presented by protein misassembly. Emphasis is on human biology applications, the area in which there is the most interest, in which most of the work has already been done, and in which there is the best evidence for the structural sophisitication of the protein aggregates. The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today--truly an essential publication for researchers in all fields of life sciences.

Author : Vladimir N. Uversky,Anthony Fink
Publisher : Springer Science & Business Media
Page : 450 pages
File Size : 54,5 Mb
Release : 2007-11-24
Category : Science
ISBN : 9780387259192

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Protein Misfolding, Aggregation and Conformational Diseases by Vladimir N. Uversky,Anthony Fink Pdf

Research indicates that most neurodegenerative diseases, systemic amyloidoses and many others, arise from the misfolding and aggregation of an underlying protein. This is the first book to discuss significant achievements in protein structure-function relationships in biochemistry, molecular biology and molecular medicine. The authors summarize recent progress in the understanding of the relationships between protein misfolding, aggregation and development of protein deposition disorders.

Author : Matthias Gaestel
Publisher : Springer Science & Business Media
Page : 464 pages
File Size : 45,8 Mb
Release : 2005-09-27
Category : Science
ISBN : 3540258752

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Molecular Chaperones in Health and Disease by Matthias Gaestel Pdf

Molecular chaperones are involved in a wide variety of essential cellular processes in living cells. A subset of molecular chaperones have been initially described as heat shock proteins protecting cells from stress damage by keeping cellular proteins in a folding competent state and preventing them from irreversible aggregation. Later it became obvious that molecular chaperones are also expressed constitutively in the cell and are involved in complex processes such as protein synthesis, intracellular protein transport, post-translational modification and secretion of proteins as well as receptor signalling. Hence, it is not surprising that molecular chaperones are implicated in the pathogenesis of many relevant diseases and could be regarded as potential pharmacological targets. Starting with the analysis of the mode of action of chaperones at the molecular, cellular and organismic level, this book will then describe specific aspects where modulation of chaperone action could be of pharmacological and therapeutic interest.

Author : Anonim
Publisher : Academic Press
Page : 464 pages
File Size : 41,9 Mb
Release : 2011-02-14
Category : Science
ISBN : 9780123859297

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The Unfolded Protein Response and Cellular Stress by Anonim Pdf

This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights. This volume provides descriptions of the occurrence of the UPR, methods used to assess it, pharmacological tools and other methodological approaches to analyze its impact on cellular regulation. The authors explain how these methods are able to provide important biological insights.