Analysis Of Biological Systems

Author : Qingling Zhang,Chao Liu,Xue Zhang
Publisher : Springer
Page : 236 pages
File Size : 47,8 Mb
Release : 2012-02-16
Category : Technology & Engineering
ISBN : 9781447123033

Get Book

Complexity, Analysis and Control of Singular Biological Systems by Qingling Zhang,Chao Liu,Xue Zhang Pdf

Complexity, Analysis and Control of Singular Biological Systems follows the control of real-world biological systems at both ecological and phyisological levels concentrating on the application of now-extensively-investigated singular system theory. Much effort has recently been dedicated to the modelling and analysis of developing bioeconomic systems and the text establishes singular examples of these, showing how proper control can help to maintain sustainable economic development of biological resources. The book begins from the essentials of singular systems theory and bifurcations before tackling the use of various forms of control in singular biological systems using examples including predator-prey relationships and viral vaccination and quarantine control. Researchers and graduate students studying the control of complex biological systems are shown how a variety of methods can be brought to bear and practitioners working with the economics of biological systems and their control will also find the monograph illuminating.

Author : G.K. Suraishkumar
Publisher : Springer
Page : 267 pages
File Size : 50,8 Mb
Release : 2014-07-08
Category : Technology & Engineering
ISBN : 9783642544682

Get Book

Continuum Analysis of Biological Systems by G.K. Suraishkumar Pdf

This book addresses the analysis, in the continuum regime, of biological systems at various scales, from the cellular level to the industrial one. It presents both fundamental conservation principles (mass, charge, momentum and energy) and relevant fluxes resulting from appropriate driving forces, which are important for the analysis, design and operation of biological systems. It includes the concept of charge conservation, an important principle for biological systems that is not explicitly covered in any other book of this kind. The book is organized in five parts: mass conservation; charge conservation; momentum conservation; energy conservation and multiple conservations simultaneously applied. All mathematical aspects are presented step by step, allowing any reader with a basic mathematical background (calculus, differential equations, linear algebra, etc.) to follow the text with ease. The book promotes an intuitive understanding of all the relevant principles and in so doing facilitates their application to practical issues related to design and operation of biological systems. Intended as a self-contained textbook for students in biotechnology and in industrial, chemical and biomedical engineering, this book will also represent a useful reference guide for professionals working in the above-mentioned fields.

Author : J. Schnakenberg
Publisher : Springer Science & Business Media
Page : 157 pages
File Size : 53,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642679711

Get Book

Thermodynamic Network Analysis of Biological Systems by J. Schnakenberg Pdf

The first edition of this book was greeted with broad interest from readers en gaged in various disciplines of biophysics. I received many stimulating and en couraging responses, however, some of the book's reviewers wanted to stress the fact that an extensive literature of network theory was not included or reported in the book. But the main aspect of the book is intended to be substantive rather than methodical: networks simply serve as a remedy for doing some first steps in analysing and modelling complex biological systems. For an advanced stage in the investigation of a particular system it may be appropriate to replace the pheno menological network method by more detailed techniques like statistical equations or computer simulations. According to this intention, the second edition of the book has been enlarged by further biological examples for network analysis, not by more network theory. There is a completely new section on a network model for photoreception. For this section I am obliged to J. Tiedge who did most of the detailed calculation and to my colleague Professor Stieve with whom we have had a very fruitful cooperation. Also I would like to mention that this work has been sponsored by the "Deutsche Forschungsgemei nschaft" i n the "Sonderforschungsberei ch 160". Recent results for excitable systems represented by feedback networks have also been included in the second edition, especially for limit cycle networks.

Author : Corrado Priami,Melissa J Morine
Publisher : World Scientific
Page : 432 pages
File Size : 53,7 Mb
Release : 2015-01-29
Category : Science
ISBN : 9781783266890

Get Book

Analysis of Biological Systems by Corrado Priami,Melissa J Morine Pdf

Modeling is fast becoming fundamental to understanding the processes that define biological systems. High-throughput technologies are producing increasing quantities of data that require an ever-expanding toolset for their effective analysis and interpretation. Analysis of high-throughput data in the context of a molecular interaction network is particularly informative as it has the potential to reveal the most relevant network modules with respect to a phenotype or biological process of interest. Analysis of Biological Systems collects classical material on analysis, modeling and simulation, thereby acting as a unique point of reference. The joint application of statistical techniques to extract knowledge from big data and map it into mechanistic models is a current challenge of the field, and the reader will learn how to build and use models even if they have no computing or math background. An in-depth analysis of the currently available technologies, and a comparison between them, is also included. Unlike other reference books, this in-depth analysis is extended even to the field of language-based modeling. The overall result is an indispensable, self-contained and systematic approach to a rapidly expanding field of science. Contents:Algorithmic Systems BiologySetting the ContextSystems and ModelsStatic Modeling TechnologiesDynamic Modeling TechnologiesLanguage-based ModelingDynamic Modeling ProcessSimulationPerspectives and ConclusionsAppendix A: Basic MathAppendix B: Probability and StatisticsAppendix C: Semantics of Modeling Languages Readership: Graduate students in computer science, physics, mathematics or engineering or biology-related fields who want to better understand how to develop and use models of biological systems. Practitioners in systems biology who want to understand algorithmic modeling and algorithmic systems biology. Key Features:The book jointly deals with static (statistical) and dynamic (simulation) technologies making it a strong reference for who wants to approach real systems biology problemsThe content of the book is the result of more than ten years application of the material in university courses and to industrial-level problems in systems pharmacology and systems nutritionThere is no reference work available for the field of language-based modeling that is studied in depth in this bookKeywords:Modeling;Simulation;Network Analysis;Systems Biology;Systems Nutrition;Systems Pharmacology;Stochastic Models;Programming Biology;Multivariate Analysis

Author : Andres Kriete,Roland Eils
Publisher : Academic Press
Page : 548 pages
File Size : 43,9 Mb
Release : 2013-11-26
Category : Computers
ISBN : 9780124059382

Get Book

Computational Systems Biology by Andres Kriete,Roland Eils Pdf

This comprehensively revised second edition of Computational Systems Biology discusses the experimental and theoretical foundations of the function of biological systems at the molecular, cellular or organismal level over temporal and spatial scales, as systems biology advances to provide clinical solutions to complex medical problems. In particular the work focuses on the engineering of biological systems and network modeling. Logical information flow aids understanding of basic building blocks of life through disease phenotypes Evolved principles gives insight into underlying organizational principles of biological organizations, and systems processes, governing functions such as adaptation or response patterns Coverage of technical tools and systems helps researchers to understand and resolve specific systems biology problems using advanced computation Multi-scale modeling on disparate scales aids researchers understanding of dependencies and constraints of spatio-temporal relationships fundamental to biological organization and function.

Author : Arianna Bianchi,Thomas Hillen,Mark A. Lewis,Yingfei Yi
Publisher : Springer Nature
Page : 267 pages
File Size : 53,9 Mb
Release : 2019-10-02
Category : Mathematics
ISBN : 9783030225834

Get Book

The Dynamics of Biological Systems by Arianna Bianchi,Thomas Hillen,Mark A. Lewis,Yingfei Yi Pdf

The book presents nine mini-courses from a summer school, Dynamics of Biological Systems, held at the University of Alberta in 2016, as part of the prestigious seminar series: Séminaire de Mathématiques Supérieures (SMS). It includes new and significant contributions in the field of Dynamical Systems and their applications in Biology, Ecology, and Medicine. The chapters of this book cover a wide range of mathematical methods and biological applications. They - explain the process of mathematical modelling of biological systems with many examples, - introduce advanced methods from dynamical systems theory, - present many examples of the use of mathematical modelling to gain biological insight - discuss innovative methods for the analysis of biological processes, - contain extensive lists of references, which allow interested readers to continue the research on their own. Integrating the theory of dynamical systems with biological modelling, the book will appeal to researchers and graduate students in Applied Mathematics and Life Sciences.

Author : Heinz Koeppl,Douglas Densmore,Gianluca Setti,Mario di Bernardo
Publisher : Springer Science & Business Media
Page : 407 pages
File Size : 53,9 Mb
Release : 2011-05-21
Category : Technology & Engineering
ISBN : 9781441967664

Get Book

Design and Analysis of Biomolecular Circuits by Heinz Koeppl,Douglas Densmore,Gianluca Setti,Mario di Bernardo Pdf

The book deals with engineering aspects of the two emerging and intertwined fields of synthetic and systems biology. Both fields hold promise to revolutionize the way molecular biology research is done, the way today’s drug discovery works and the way bio-engineering is done. Both fields stress the importance of building and characterizing small bio-molecular networks in order to synthesize incrementally and understand large complex networks inside living cells. Reminiscent of computer-aided design (CAD) of electronic circuits, abstraction is believed to be the key concept to achieve this goal. It allows hiding the overwhelming complexity of cellular processes by encapsulating network parts into abstract modules. This book provides a unique perspective on how concepts and methods from CAD of electronic circuits can be leveraged to overcome complexity barrier perceived in synthetic and systems biology.

Author : G. Venkatesh Iyengar,K. S. Subramanian,Joost R.W. Woittiez
Publisher : CRC Press
Page : 278 pages
File Size : 49,8 Mb
Release : 2020-11-25
Category : Science
ISBN : 9781000141726

Get Book

Element Analysis of Biological Samples by G. Venkatesh Iyengar,K. S. Subramanian,Joost R.W. Woittiez Pdf

Despite the development of innovative new analytical techniques for biological trace element research, today's trace element investigators face formidable obstacles to obtaining reliable data. This complete reference identifies and assesses the challenges the analyst encounters at each stage of an analysis, and discusses the effects of various techniques on the sample. Three internationally recognized scientists and authors consider the effects of the numerous collection, storage, and sample preparatory techniques used in sample analysis. Proper analytical quality control, including such critical factors as sampling and sample preparation, specimen preservation and storage, and ashing, is examined. The book also looks at sample preparation methods unique to various instruments and speciation chemistry issues, and examines the link between chemical analysis and specimen banking. A previously unrecognized source of error, presampling factors, is also discussed.

Author : Qiang Cui,Ivet Bahar
Publisher : CRC Press
Page : 432 pages
File Size : 46,8 Mb
Release : 2005-12-12
Category : Medical
ISBN : 9781420035070

Get Book

Normal Mode Analysis by Qiang Cui,Ivet Bahar Pdf

Rapid developments in experimental techniques continue to push back the limits in the resolution, size, and complexity of the chemical and biological systems that can be investigated. This challenges the theoretical community to develop innovative methods for better interpreting experimental results. Normal Mode Analysis (NMA) is one such technique. Capable of providing unique insights into the structural and dynamical properties of complex systems, it is now finding a wide range of applications in chemical and biological problems. From the fundamental physical ideas to cutting-edge applications and beyond, this book presents a broad overview of normal mode analysis and its value in state-of-the-art research. The first section introduces NMA, examines NMA algorithm development at different resolutions, and explores the application of those techniques in the study of biological systems. Later chapters cover method developments based on or inspired by NMA but going beyond the harmonic approximation inherent in standard NMA techniques. Normal mode analysis complements traditional approaches with computational efficiency and applicability to large systems that are beyond the reach of older methods. This book offers a unique opportunity to learn from the experiences of an international, interdisciplinary panel of top researchers and explore the latest developments and applications of NMA to biophysical and chemical problems.

Author : Samuli Niiranen,Andre Ribeiro
Publisher : Springer Science & Business Media
Page : 230 pages
File Size : 44,8 Mb
Release : 2011-03-10
Category : Technology & Engineering
ISBN : 9783642196218

Get Book

Information Processing and Biological Systems by Samuli Niiranen,Andre Ribeiro Pdf

Living beings require constant information processing for survival. In cells, information is being processed and propagated at various levels, from the gene regulatory network to chemical pathways, to the interaction with the environment. How this is achieved and how information is coded is still poorly understood. For example, what a cell interprets as information in the temporal level of an mRNA and what is interpreted as noise remains an open question. Recently, information theoretical methods and other tools, developed in the context of engineering and natural sciences, have been applied to study diverse biological processes. This book covers the latest findings on how information is processed in various biological processes, ranging from information processing and propagation in gene regulatory networks to information processing in natural language. An overview is presented of the state-of-the-art in information processing in biological systems and the opinion of current leaders in this research field on future research directions.

Author : A. Favier
Publisher : Springer Science & Business Media
Page : 332 pages
File Size : 49,6 Mb
Release : 1995-11-29
Category : Gardening
ISBN : 3764351373

Get Book

Analysis of Free Radicals in Biological Systems by A. Favier Pdf

In addition, several assays are provided to assess the chemical damage induced by reactive oxygen species in critical cellular-targets in vitro and in humans in vivo.

Author : Nikolay V Dokholyan
Publisher : Springer Science & Business Media
Page : 360 pages
File Size : 54,5 Mb
Release : 2012-02-12
Category : Science
ISBN : 9781461421450

Get Book

Computational Modeling of Biological Systems by Nikolay V Dokholyan Pdf

Computational modeling is emerging as a powerful new approach to study and manipulate biological systems. Multiple methods have been developed to model, visualize, and rationally alter systems at various length scales, starting from molecular modeling and design at atomic resolution to cellular pathways modeling and analysis. Higher time and length scale processes, such as molecular evolution, have also greatly benefited from new breeds of computational approaches. This book provides an overview of the established computational methods used for modeling biologically and medically relevant systems.

Author : Jinzhi Lei
Publisher : Springer Nature
Page : 308 pages
File Size : 45,5 Mb
Release : 2021-05-13
Category : Mathematics
ISBN : 9783030730338

Get Book

Systems Biology by Jinzhi Lei Pdf

This book discusses the mathematical simulation of biological systems, with a focus on the modeling of gene expression, gene regulatory networks and stem cell regeneration. The diffusion of morphogens is addressed by introducing various reaction-diffusion equations based on different hypotheses concerning the process of morphogen gradient formation. The robustness of steady-state gradients is also covered through boundary value problems. The introduction gives an overview of the relevant biological concepts (cells, DNA, organism development) and provides the requisite mathematical preliminaries on continuous dynamics and stochastic modeling. A basic understanding of calculus is assumed. The techniques described in this book encompass a wide range of mechanisms, from molecular behavior to population dynamics, and the inclusion of recent developments in the literature together with first-hand results make it an ideal reference for both new students and experienced researchers in the field of systems biology and applied mathematics.

Author : Abdelghani Bellouquid,Marcello Delitala
Publisher : Springer Science & Business Media
Page : 194 pages
File Size : 55,9 Mb
Release : 2006-08-17
Category : Science
ISBN : 9780817643959

Get Book

Mathematical Modeling of Complex Biological Systems by Abdelghani Bellouquid,Marcello Delitala Pdf

This book describes the evolution of several socio-biological systems using mathematical kinetic theory. Specifically, it deals with modeling and simulations of biological systems whose dynamics follow the rules of mechanics as well as rules governed by their own ability to organize movement and biological functions. It proposes a new biological model focused on the analysis of competition between cells of an aggressive host and cells of a corresponding immune system. Proposed models are related to the generalized Boltzmann equation. The book may be used for advanced graduate courses and seminars in biological systems modeling.

Author : Cedric Lhoussaine,Elisabeth Remy
Publisher : John Wiley & Sons
Page : 404 pages
File Size : 52,5 Mb
Release : 2023-08-29
Category : Computers
ISBN : 9781789450293

Get Book

Symbolic Approaches to Modeling and Analysis of Biological Systems by Cedric Lhoussaine,Elisabeth Remy Pdf