Analysis Of Cardiac Development

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Analysis of Cardiac Development

Rafael Beyar,Amir Landesberg
Analysis of Cardiac Development Book PDF

Author : Rafael Beyar,Amir Landesberg
Publisher : John Wiley & Sons
Page : 241 pages
File Size : 47,8 Mb
Release : 2010-03-22
Category : Science
ISBN : 9781573317474

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Analysis of Cardiac Development by Rafael Beyar,Amir Landesberg Pdf

This volume, the result of three days of interactive sessions among world leaders in the cardiac sciences, summarizes the most up-to-date information about development and cardiogenesis signaling in cell-based therapy, as well as developmental aspects of the formation of the embryonic heart, including the effect of mechanical load on differentiation. Other topics covered include: signaling and repair strategies, cell and gene therapy for the treatment of postmyocardial infarction, signaling, vascularization methods in engineering embryonic cardiac tissue, and molecular methods to improve survival of human embryonic stem cell–derived cardiomyocytes; developmental and evolutional cardiology; novel strategies for treatment of atrial fibrillation and channel molecular physiology in remodeling and hypertrophy; multiscale modeling for metabolism and flows, including force development, mechanics of cardiac contraction, and ATP supply and demand aspects; aging, interactions, and interference aspects include fibroblast-myocyte-capillary communications, nonuniformities in contraction, calcium channels as oxygen sensors, and epigenetics of heart failure; and macroscale phenomena and clinical aspects, including various clinical aspects of modern cardiology such as navigation methods for cardiac interventions and control of cardiac function by changes in energetic demand. NOTE: Annals volumes are available for sale as individual books or as a journal. For information on institutional journal subscriptions, please visit www.blackwellpublishing.com/nyas. ACADEMY MEMBERS: Please contact the New York Academy of Sciences directly to place your order (www.nyas.org). Members of the New York Academy of Science receive full-text access to the Annals online and discounts on print volumes. Please visit http://www.nyas.org/MemberCenter/Join.aspx for more information about becoming a member.

Heart Development

Richard P. Harvey,Nadia Rosenthal
Heart Development Book PDF

Author : Richard P. Harvey,Nadia Rosenthal
Publisher : Gulf Professional Publishing
Page : 574 pages
File Size : 46,7 Mb
Release : 1999
Category : Medical
ISBN : 0123298601

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Heart Development by Richard P. Harvey,Nadia Rosenthal Pdf

Contributors. -- Preface. -- C. Seidman, Introduction. -- I. Origins and Early Morphogenesis: -- P.P.L. Tam and G.C. Schoenwolf, Cardiac Fate Maps: Lineage Allocation, Morphogenetic Movement, and Cell Commitment. -- T. Mikawa, Cardiac Lineages. -- II. Cardiac Induction: -- T.J. Mohun and L.M. Leong, Heart Formation and the Heart Field in Amphibian Embryos. -- T.M. Schultheiss and A.B. Lassar, Vertebrate Heart Induction. -- III. Genetic Dissection of Heart Development: -- R. Bodmer and M. Frasch, Genetic Determination in Drosophilia Heart Development. -- J. Alexander and D.Y.R. Stainier, Mutations Affecting Cardiac Development in Zebrafish. -- R.P. Harvey, C. Biben, and D.A. Elliott, Transcriptional Control and Pattern Formation in the Developing Vertebrate Heart: Studies on NK-2 Class Homeodomain Factors. -- B.L. Black and E.N. Olson, Control of Cardiac Development by the Family of MEF2 Transcription Factors. -- D. Srivastava, Segmental Regulation of Cardiac Development by the Basic He ...

Cardiac Development

Margaret L. Kirby
Cardiac Development Book PDF

Author : Margaret L. Kirby
Publisher : Oxford University Press
Page : 288 pages
File Size : 49,5 Mb
Release : 2007-03-22
Category : Medical
ISBN : 019972086X

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Cardiac Development by Margaret L. Kirby Pdf

This is the only in-depth, single author survey of heart development. It will provide a more systematic, up-to-date synthesis of the subject than any other volume, spanning the range from classical anatomical studies to recent findings in molecular biology. It also covers topics that are often omitted from discussions of heart development, such as myocardial function, cardiac innervation, and conduction development and clinical correlates will be discussed throughout. The book is beautifully illustrated by Karen Waldo, an artist who has collaborated with Dr. Kirby for many years.

Heart Development and Regeneration

Nadia Rosenthal,Richard P. Harvey
Heart Development and Regeneration Book PDF

Author : Nadia Rosenthal,Richard P. Harvey
Publisher : Academic Press
Page : 1136 pages
File Size : 54,9 Mb
Release : 2010-05-28
Category : Science
ISBN : 9780123813336

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Heart Development and Regeneration by Nadia Rosenthal,Richard P. Harvey Pdf

The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration. Authored by world experts in heart development and disease New research on epigenetic modifiers in cardiac development Comprehensive coverage of stem cells and prospects for cardiac regeneration Up-to-date research on transcriptional and proteomic circuits in cardiac disease Full-color, detailed illustrations

Cardiovascular Development

Anonim
Cardiovascular Development Book PDF

Author : Anonim
Publisher : Elsevier
Page : 454 pages
File Size : 46,7 Mb
Release : 2007-11-13
Category : Science
ISBN : 9780080554389

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Cardiovascular Development by Anonim Pdf

In 1993, Rolf Bodmer described a gene he named tinman that was required for the formation of the dorsal aorta of the fly. Flies without a functional tinman gene had no heart. Quickly, mammalian counterparts of the tinman gene were identified and found to be expressed by early cardiomyogenic precursors and by cardiomyocytes throughout heart development. Since then, significant progress has been made in the understanding of molecular and genetic determinants of heart formation. An ever growing number of genes have been identified that are required for cardiogenesis, as evidenced by severe abnormalities in cardiac development produced by inactivation in the mouse or inhibition of gene function in other model organisms. Cardiovascular Development covers some of the latest research in the study of heart formation. Volume Editor Rolf Bodmer has assembled a world-class list of contributors whose research uses a variety of animal models and whose findings are certain to enhance our understanding of this exciting field. * Ties together the development of heart morphology and conduction system * The latest developments in vertebrate and invertebrate genetic model systems * Technological advancements in cardiovascular science

Pathophysiology of Cardiovascular Disease

Naranjan S. Dhalla,Heinz Rupp,Aubie Angel,Grant Pierce
Pathophysiology of Cardiovascular Disease Book PDF

Author : Naranjan S. Dhalla,Heinz Rupp,Aubie Angel,Grant Pierce
Publisher : Springer
Page : 648 pages
File Size : 49,5 Mb
Release : 2012-10-31
Category : Medical
ISBN : 1461350840

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Pathophysiology of Cardiovascular Disease by Naranjan S. Dhalla,Heinz Rupp,Aubie Angel,Grant Pierce Pdf

Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.

Promoting Cardiovascular Health in the Developing World

Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
Promoting Cardiovascular Health in the Developing World Book PDF

Author : Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries
Publisher : National Academies Press
Page : 483 pages
File Size : 48,9 Mb
Release : 2010-06-29
Category : Medical
ISBN : 9780309157612

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Promoting Cardiovascular Health in the Developing World by Institute of Medicine,Board on Global Health,Committee on Preventing the Global Epidemic of Cardiovascular Disease: Meeting the Challenges in Developing Countries Pdf

Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.

Etiology and Morphogenesis of Congenital Heart Disease

Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
Etiology and Morphogenesis of Congenital Heart Disease Book PDF

Author : Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi
Publisher : Springer
Page : 0 pages
File Size : 50,6 Mb
Release : 2018-06-07
Category : Medical
ISBN : 4431566333

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Etiology and Morphogenesis of Congenital Heart Disease by Toshio Nakanishi,Roger R. Markwald,H.Scott Baldwin,Bradley B. Keller,Deepak Srivastava,Hiroyuki Yamagishi Pdf

This volume focuses on the etiology and morphogenesis of congenital heart diseases. It reviews in detail the early development and differentiation of the heart, and later morphologic events of the cardiovascular system, covering a wide range of topics such as gene functions, growth factors, transcription factors and cellular interactions that are implicated in cardiac morphogenesis and congenital heart disease. This book also presents recent advances in stem cell and cell sheet tissue engineering technologies which have the potential to provide novel in vitro disease models and to generate regenerative paradigms for cardiac repair and regeneration. This is the ideal resource for physician scientists and investigators looking for updates on recent investigations on the origins of congenital heart disease and potential future therapies.

Handbook of Cardiac Anatomy, Physiology, and Devices

Paul A. Iaizzo
Handbook of Cardiac Anatomy Physiology and Devices Book PDF

Author : Paul A. Iaizzo
Publisher : Springer
Page : 817 pages
File Size : 45,6 Mb
Release : 2015-11-13
Category : Medical
ISBN : 9783319194646

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Handbook of Cardiac Anatomy, Physiology, and Devices by Paul A. Iaizzo Pdf

This book covers the latest information on the anatomic features, underlying physiologic mechanisms, and treatments for diseases of the heart. Key chapters address animal models for cardiac research, cardiac mapping systems, heart-valve disease and genomics-based tools and technology. Once again, a companion of supplementary videos offer unique insights into the working heart that enhance the understanding of key points within the text. Comprehensive and state-of-the art, the Handbook of Cardiac Anatomy, Physiology and Devices, Third Edition provides clinicians and biomedical engineers alike with the authoritative information and background they need to work on and implement tomorrow’s generation of life-saving cardiac devices.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi
Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension Book PDF

Author : Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi
Publisher : Springer Nature
Page : 374 pages
File Size : 52,5 Mb
Release : 2020-02-28
Category : Medical
ISBN : 9789811511851

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Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension by Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi Pdf

This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Cardiovascular Disability

Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria
Cardiovascular Disability Book PDF

Author : Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria
Publisher : National Academies Press
Page : 304 pages
File Size : 50,9 Mb
Release : 2010-12-04
Category : Medical
ISBN : 9780309156981

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Cardiovascular Disability by Institute of Medicine,Board on the Health of Select Populations,Committee on Social Security Cardiovascular Disability Criteria Pdf

The Social Security Administration (SSA) uses a screening tool called the Listing of Impairments to identify claimants who are so severely impaired that they cannot work at all and thus immediately qualify for benefits. In this report, the IOM makes several recommendations for improving SSA's capacity to determine disability benefits more quickly and efficiently using the Listings.

Global Cardiac Surgery Capacity Development in Low and Middle Income Countries

Jacques Kpodonu
Global Cardiac Surgery Capacity Development in Low and Middle Income Countries Book PDF

Author : Jacques Kpodonu
Publisher : Springer Nature
Page : 541 pages
File Size : 50,8 Mb
Release : 2021-11-22
Category : Medical
ISBN : 9783030838645

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Global Cardiac Surgery Capacity Development in Low and Middle Income Countries by Jacques Kpodonu Pdf

This book provides a focused resource on how cardiac surgery capacity can be developed and how it assists in the sustainable development and strengthening of associated health systems. Background is provided on the extent of the problems that are experienced in many nations with suggestions for how suitable frameworks can be developed to improve cardiac healthcare provision. Relevant aspects of governance, financial modelling and disease surveillance are all covered. Guidance is also given on how to found and nurture cardiac surgery curriculum and residency programs. Global Cardiac Surgery Capacity Development in Low and Middle Income Countries provides a practically applicable resource on how to treat cardiac patients with limited resources. It identifies the key challenges and presents strategies on how these can be managed, therefore making it a critical tool for those involved in this field.

A Whole-hearted Journey

Rebecca J. Salamon
A Whole hearted Journey Book PDF

Author : Rebecca J. Salamon
Publisher : Unknown
Page : 0 pages
File Size : 48,7 Mb
Release : 2023
Category : Electronic
ISBN : OCLC:1434588308

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A Whole-hearted Journey by Rebecca J. Salamon Pdf

My thesis highlights important discoveries about the pathways and patterns regulating cardiac development, disease, and regeneration. A central regulator of cardiovascular physiology and pathology is the cardiac nervous system, composed of sympathetic, parasympathetic, and sensory nerves. Yet, our understanding of nerve architecture has been limited by two-dimensional analysis. I utilized innovative technologies, including tissue clearing methods and three-dimensional (3D) analysis, to investigate the intact cardiac nervous system. My 3D approach provides a basis for investigating typical cardiac nerve architecture, as well as nerve remodeling in diseased and regenerative settings. My research identified extensive parasympathetic innervation in the cardiac ventricles and a novel phenotype of intertwined parasympathetic and sympathetic axons. I also discovered differences in axon remodeling between the regenerative and non-regenerative mouse heart, demonstrating that the regenerating neonatal heart undergoes a unique process of physiological reinnervation. This neural plasticity may be harnessed therapeutically to prevent arrhythmias after cardiac injury. Additionally, I explored the role of the cellular metabolic state and specific proteins, such as Leucine-rich repeat containing 10 (LRRC10), in promoting neonatal and adult mammalian cardiac regeneration. These studies have direct clinical implications for promoting endogenous cardiac regeneration for the treatment of heart failure, given that current treatments are limited. Furthermore, these findings provide a framework for identifying novel pathways and molecular targets that could reawaken the regenerative response in the adult heart after injury. Taken together, my research represents a significant step forward in understanding the pathways and patterns underpinning heart development, disease, and regeneration, highlighting exciting new opportunities for developing therapeutic interventions that promote cardiac repair.

From Hypertension to Heart Failure

Michael Böhm,John H. Laragh,Manfred Zehender
From Hypertension to Heart Failure Book PDF

Author : Michael Böhm,John H. Laragh,Manfred Zehender
Publisher : Springer
Page : 276 pages
File Size : 48,8 Mb
Release : 1998-04-16
Category : Gardening
ISBN : UOM:39015046892959

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From Hypertension to Heart Failure by Michael Böhm,John H. Laragh,Manfred Zehender Pdf

The book "From Hypertension to Heart Failure" will cover new aspects of the treatment of hypertension, arrhythmias, heart failure and coronary artery diseases. The topics will include new pathophysiological findings, the theoretical background of pharmacological treatment, results of the latest studies, and practical guidelines for treatment. Case reports will make the book applicable for a broad readership of general internists. The therapy of heart failure with betablockers is one of the most controversially discussed topics in cardiovascular medicine. Therefore, the book will critically deal with this new form of therapy for this disabling condition.

Development of the Cardiac Conduction System

Derek J. Chadwick,Jamie A. Goode
Development of the Cardiac Conduction System Book PDF

Author : Derek J. Chadwick,Jamie A. Goode
Publisher : John Wiley & Sons
Page : 300 pages
File Size : 48,9 Mb
Release : 2005-01-21
Category : Medical
ISBN : 9780470868034

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Development of the Cardiac Conduction System by Derek J. Chadwick,Jamie A. Goode Pdf

The pacemaking and conduction system (PCS) is vital for generating and synchronizing the heart beat. Dysfunction of this system can be a direct cause of cardiac conduction disturbance, arrhythmias and sudden cardiac death. A wealth of information has been collected over many years on the unique histological, morphological and phenotypic characteristics of specialized cardiac tissues. The cellular and molecular mechanisms that govern development of the PCS are now starting to be understood. This book draws together contributions from an international and interdisciplinary group of experts working on both basic and clinical aspects of cardiac development. It features reviews of the structure and function of the developing PCS, discussion of the molecular and cellular mechanisms regulating embryological development of this system and studies on the fundamental basis of PCS pathology. The book also considers how novel therapeutic interventions based on understanding of the developmental biology of cardiac pacemaking and conduction tissues might ultimately impact on clinical medicine.