Analysis Of Physiological Systems

Author : Vasilis Marmarelis
Publisher : Springer Science & Business Media
Page : 495 pages
File Size : 51,5 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9781461339700

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Analysis of Physiological Systems by Vasilis Marmarelis Pdf

In studying physiological systems bioscientists are continually faced with the problem of providing descriptions of cause-effect relationships. This task is usually carried out through the performance of stimulus-response experiments. In the past, the design of such experiments has been ad hoc, incomplete, and certainly inefficient. Worse yet, bioscientists have failed to take advantage of advances in fields directly related to their problems (specifically, advances in the area of systems analysis). The raison d'etre of this book is to rectify this deficiency by providing the physiologist with methodological tools that will be useful to him or her in everyday labora tory encounters with physiological systems. The book was written so that it would be practical, useful, and up-to date. With this in mind, parts of it give step-by-step descriptions of in the laboratory. It is hoped that this systematic procedures to be followed will increase the usefulness of the book to the average research physiologist and, perhaps, reduce the need for in-depth knowledge of some of the associated mathematics. Even though the material deals with state-of-the art techniques in systems and signal analysis, the mathematical level has been kept low so as to be comprehensible to the average physiologist with no extensive training in mathematics. To this end, mathematical rigor is often sacrificed readily to intuitive simple arguments.

Author : Michael C. K. Khoo
Publisher : John Wiley & Sons
Page : 456 pages
File Size : 55,9 Mb
Release : 2018-04-12
Category : Science
ISBN : 9781119058809

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Physiological Control Systems by Michael C. K. Khoo Pdf

A guide to common control principles and how they are used to characterize a variety of physiological mechanisms The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications to physiology of nonlinear dynamics, parameter estimation methods, and adaptive estimation and control. The author—a noted expert in the field—includes a wealth of worked examples that illustrate key concepts and methodology and offers in-depth analyses of selected physiological control models that highlight the topics presented. The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on common control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource: Offers new sections that explore identification of nonlinear and time-varying systems, and provide the background for understanding the link between continuous-time and discrete-time dynamic models Presents helpful, hands-on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter Written for biomedical engineering students and biomedical scientists, Physiological Control Systems, offers an updated edition of this key resource for understanding classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.

Author : Suresh R. Devasahayam
Publisher : Springer Science & Business Media
Page : 348 pages
File Size : 42,5 Mb
Release : 2012-12-06
Category : Technology & Engineering
ISBN : 9781461542995

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Signals and Systems in Biomedical Engineering by Suresh R. Devasahayam Pdf

In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.

Author : Vasilis Marmarelis
Publisher : Unknown
Page : 508 pages
File Size : 47,7 Mb
Release : 1978-07-01
Category : Electronic
ISBN : 1461339715

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Analysis of Physiological Systems by Vasilis Marmarelis Pdf

Author : Michael Chappell,Stephen Payne
Publisher : Springer Nature
Page : 179 pages
File Size : 51,6 Mb
Release : 2020-04-27
Category : Technology & Engineering
ISBN : 9783030397050

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Physiology for Engineers by Michael Chappell,Stephen Payne Pdf

This book provides an introduction to qualitative and quantitative aspects of human physiology. It examines biological and physiological processes and phenomena, including a selection of mathematical models, showing how physiological problems can be mathematically formulated and studied. It also illustrates how a wide range of engineering and physics topics, such as electronics, fluid dynamics, solid mechanics and control theory can be used to describe and understand physiological processes and systems. Throughout the text, there are introductions to measuring and quantifying physiological processes using both signaling and imaging technologies. This new edition includes updated material on pathophysiology, metabolism and the TCA cycle, as well as more advanced worked examples. This book describes the basic structure and models of cellular systems, the structure and function of the cardiovascular system, and the electrical and mechanical activity of the heart, and provides an overview of the structure and function of the respiratory and nervous systems. It also includes an introduction to the basic concepts and applications of reaction kinetics, pharmacokinetic modelling and tracer kinetics. It appeals to final year biomedical engineering undergraduates and graduates alike, as well as to practising engineers new to the fields of bioengineering or medical physics.

Author : Erol Basar,Erol Başar
Publisher : Westview Press
Page : 429 pages
File Size : 52,9 Mb
Release : 1976
Category : Biological control systems
ISBN : 0201008475

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Biophysical and Physiological Systems Analysis by Erol Basar,Erol Başar Pdf

Author : Paolo Castiglioni,Luca Faes,Gaetano Valenza
Publisher : MDPI
Page : 296 pages
File Size : 42,7 Mb
Release : 2021-03-02
Category : Mathematics
ISBN : 9783039433681

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Assessing Complexity in Physiological Systems through Biomedical Signals Analysis by Paolo Castiglioni,Luca Faes,Gaetano Valenza Pdf

Complexity is a ubiquitous phenomenon in physiology that allows living systems to adapt to external perturbations. Fractal structures, self-organization, nonlinearity, interactions at different scales, and interconnections among systems through anatomical and functional networks, may originate complexity. Biomedical signals from physiological systems may carry information about the system complexity useful to identify physiological states, monitor health, and predict pathological events. Therefore, complexity analysis of biomedical signals is a rapidly evolving field aimed at extracting information on the physiological systems. This book consists of 16 contributions from authors with a strong scientific background in biomedical signals analysis. It includes reviews on the state-of-the-art of complexity studies in specific medical applications, new methods to improve complexity quantifiers, and novel complexity analyses in physiological or clinical scenarios. It presents a wide spectrum of methods investigating the entropic properties, multifractal structure, self-organized criticality, and information dynamics of biomedical signals touching upon three physiological areas: the cardiovascular system, the central nervous system, the heart-brain interactions. The book is aimed at experienced researchers in signal analysis and presents the latest trends in the complexity methods in physiology and medicine with the hope of inspiring future works advancing this fascinating area of research.

Author : Hanns-Christian Gunga
Publisher : Academic Press
Page : 376 pages
File Size : 43,7 Mb
Release : 2020-10-18
Category : Science
ISBN : 9780128159439

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Human Physiology in Extreme Environments by Hanns-Christian Gunga Pdf

Human Physiology in Extreme Environments, Second Edition, offers evidence on how human biology and physiology is affected by extreme environments, also highlighting technological innovations that allow us to adapt and regulate environments. Covering a broad range of extreme environments, including high altitude, underwater, tropical climates, desert climates, arctic climates and space travel, the book also includes case studies that can be used to illustrate practical application. Graduate students, medical students and researchers will find this to be an interesting, informative and useful resource for human physiology, environmental physiology and medical studies. Includes coverage of current global challenges and their consequences on human physiology and performance Presents human physiological challenges in extreme environments Provides an excellent source of information on paleontological and anthropological aspects Offers practical medical and scientific uses of current concepts

Author : James G. Hollandsworth Jr.
Publisher : Springer Science & Business Media
Page : 250 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Psychology
ISBN : 9781468470239

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Physiology and Behavior Therapy by James G. Hollandsworth Jr. Pdf

Despite the widespread use of psychophysiological concepts and meth ods in behavior therapy, there is no text devoted specifically to the subject. The publication of this book is necessary and timely, and should promote a better appreciation of the physiological roots of behavior therapy. The important connections between physiology and behavior thera py receive insufficient recognition nowadays, despite the fact that his torically one of the two main streams of behavior therapy grew out of a physiological basis. Wolpe's early work was closely connected to phys iology, and in contemporary behavior therapy, Lang's critical contribu tion is firmly based in psychophysiology. The physiological component is prominent in Lang's highly productive three-systems analysis of emo tion and in its application to psychological disorders. In addition, there are philosophical reasons for maintaining the close connection between behavior therapy and physiology. The existence of these connections, and their justification, can raise few objections, and it is therefore curious that a book on this significant subject has not appeared earlier. The importance of physiology for behavior therapy can be illus trated by considering the nature of a behavior therapy deprived of its physiological connections. It would survive, certainly, but as a rather scrawny, uninteresting orphan among many clamorous competitors.

Author : Ewart Carson,Claudio Cobelli
Publisher : Newnes
Page : 588 pages
File Size : 55,6 Mb
Release : 2013-12-05
Category : Science
ISBN : 9780124095250

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Modelling Methodology for Physiology and Medicine by Ewart Carson,Claudio Cobelli Pdf

Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. Builds upon and enhances the reader's existing knowledge of modeling methodology and practice Editors are internationally renowned leaders in their respective fields Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems

Author : Michael C. K. Khoo
Publisher : John Wiley & Sons
Page : 450 pages
File Size : 44,9 Mb
Release : 2018-06-06
Category : Science
ISBN : 9781119055334

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Physiological Control Systems by Michael C. K. Khoo Pdf

A guide to common control principles and how they are used to characterize a variety of physiological mechanisms The second edition of Physiological Control Systems offers an updated and comprehensive resource that reviews the fundamental concepts of classical control theory and how engineering methodology can be applied to obtain a quantitative understanding of physiological systems. The revised text also contains more advanced topics that feature applications to physiology of nonlinear dynamics, parameter estimation methods, and adaptive estimation and control. The author—a noted expert in the field—includes a wealth of worked examples that illustrate key concepts and methodology and offers in-depth analyses of selected physiological control models that highlight the topics presented. The author discusses the most noteworthy developments in system identification, optimal control, and nonlinear dynamical analysis and targets recent bioengineering advances. Designed to be a practical resource, the text includes guided experiments with simulation models (using Simulink/Matlab). Physiological Control Systems focuses on common control principles that can be used to characterize a broad variety of physiological mechanisms. This revised resource: Offers new sections that explore identification of nonlinear and time-varying systems, and provide the background for understanding the link between continuous-time and discrete-time dynamic models Presents helpful, hands-on experimentation with computer simulation models Contains fully updated problems and exercises at the end of each chapter Written for biomedical engineering students and biomedical scientists, Physiological Control Systems, offers an updated edition of this key resource for understanding classical control theory and its application to physiological systems. It also contains contemporary topics and methodologies that shape bioengineering research today.

Author : David T. Westwick,Robert E. Kearney
Publisher : John Wiley & Sons
Page : 284 pages
File Size : 44,6 Mb
Release : 2003-08-28
Category : Technology & Engineering
ISBN : 0471274569

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Identification of Nonlinear Physiological Systems by David T. Westwick,Robert E. Kearney Pdf

Significant advances have been made in the field since the previous classic texts were written. This text brings the available knowledge up to date. * Enables the reader to use a wide variety of nonlinear system identification techniques. * Offers a thorough treatment of the underlying theory. * Provides a MATLAB toolbox containing implementation of the latest identification methods together with an extensive set of problems using realistic data sets.

Author : Professor Vasilis Z. Marmarelis
Publisher : John Wiley & Sons
Page : 564 pages
File Size : 47,6 Mb
Release : 2004-09-03
Category : Medical
ISBN : 0471469602

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Nonlinear Dynamic Modeling of Physiological Systems by Professor Vasilis Z. Marmarelis Pdf

The study of nonlinearities in physiology has been hindered by the lack of effective ways to obtain nonlinear dynamic models from stimulus-response data in a practical context. A considerable body of knowledge has accumulated over the last thirty years in this area of research. This book summarizes that progress, and details the most recent methodologies that offer practical solutions to this daunting problem. Implementation and application are discussed, and examples are provided using both synthetic and actual experimental data. This essential study of nonlinearities in physiology apprises researchers and students of the latest findings and techniques in the field.

Author : Paolo Castiglioni,Luca Faes,Gaetano Valenza
Publisher : Unknown
Page : 296 pages
File Size : 47,7 Mb
Release : 2021
Category : Electronic
ISBN : 3039433695

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Assessing Complexity in Physiological Systems Through Biomedical Signals Analysis by Paolo Castiglioni,Luca Faes,Gaetano Valenza Pdf

Complexity is a ubiquitous phenomenon in physiology that allows living systems to adapt to external perturbations. Fractal structures, self-organization, nonlinearity, interactions at different scales, and interconnections among systems through anatomical and functional networks, may originate complexity. Biomedical signals from physiological systems may carry information about the system complexity useful to identify physiological states, monitor health, and predict pathological events. Therefore, complexity analysis of biomedical signals is a rapidly evolving field aimed at extracting information on the physiological systems. This book consists of 16 contributions from authors with a strong scientific background in biomedical signals analysis. It includes reviews on the state-of-the-art of complexity studies in specific medical applications, new methods to improve complexity quantifiers, and novel complexity analyses in physiological or clinical scenarios. It presents a wide spectrum of methods investigating the entropic properties, multifractal structure, self-organized criticality, and information dynamics of biomedical signals touching upon three physiological areas: the cardiovascular system, the central nervous system, the heart-brain interactions. The book is aimed at experienced researchers in signal analysis and presents the latest trends in the complexity methods in physiology and medicine with the hope of inspiring future works advancing this fascinating area of research.

Author : James Keener,James Sneyd
Publisher : Springer Science & Business Media
Page : 547 pages
File Size : 49,9 Mb
Release : 2010-06-04
Category : Mathematics
ISBN : 9780387758473

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Mathematical Physiology by James Keener,James Sneyd Pdf

Divided into two volumes, the book begins with a pedagogical presentation of some of the basic theory, with chapters on biochemical reactions, diffusion, excitability, wave propagation and cellular homeostasis. The second, more extensive part discusses particular physiological systems, with chapters on calcium dynamics, bursting oscillations and secretion, cardiac cells, muscles, intercellular communication, the circulatory system, the immune system, wound healing, the respiratory system, the visual system, hormone physiology, renal physiology, digestion, the visual system and hearing. New chapters on Calcium Dynamics, Neuroendocrine Cells and Regulation of Cell Function have been included. Reviews from first edition: Keener and Sneyd's Mathematical Physiology is the first comprehensive text of its kind that deals exclusively with the interplay between mathematics and physiology. Writing a book like this is an audacious act! -Society of Mathematical Biology Keener and Sneyd's is unique in that it attempts to present one of the most important subfields of biology and medicine, physiology, in terms of mathematical "language", rather than organizing materials around mathematical methodology. -SIAM review