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By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the Animal Clinical Chemistry Association, a group formed to advance the science of animal clinical chemistry in safety evaluation, toxicology and veterinary science.
The Clinical Chemistry of Laboratory Animals by David M. Kurtz,Gregory S. Travlos Pdf
Key features: Serves as the detailed, authoritative source of the clinical chemistry of the most commonly used laboratory animals Includes detailed chapters dedicated to descriptions of clinical chemistry-related topics specific to each laboratory species as well as organ/class-specific chapters Presents information regarding evaluation and interpretation of a variety of individual clinical chemistry end points Concludes with detailed chapters dedicated to descriptions of statistical analyses and biomarker development of clinical chemistry-related topics Provides extensive reference lists at the end of each chapter to facilitate further study Extensively updated and expanded since the publication of Walter F. Loeb and Fred W. Quimby’s second edition in 1999, the new The Clinical Chemistry of Laboratory Animals, Third Edition continues as the most comprehensive reference on in vivo animal studies. By organizing the book into species- and organ/class-specific chapters, this book provides information to enable a conceptual understanding of clinical chemistry across laboratory species as well as information on evaluation and interpretation of clinical chemistry data relevant to specific organ systems. Now sponsored by the American College of Laboratory Animal Medicine (ACLAM), this well-respected resource includes chapters on multiple laboratory species and provides pertinent information on their unique physiological characteristics, methods for sample collection, and preanalytical sources of variation for the particular species. Basic methodology for common procedures for each species is also discussed. New Chapters in the Third Edition Include: The Laboratory Zebrafish and Other Fishes Evaluation of Cardiovascular and Pulmonary Function and Injury Evaluation of Skeletal Muscle Function and Injury Evaluation of Bone Function and Injury Vitamins Development of Biomarkers Statistical Methods The Clinical Chemistry of Laboratory Animals, Third Edition is intended as a reference for use by veterinary students, clinical veterinarians, verterinary toxicologists, veterinary clinical pathologists, and laboratory animal veterinarians to aid in study design, collection of samples, and interpretation of clinical chemistry data for laboratory species.
Manual of Veterinary Clinical Chemistry by Leslie C. Sharkey,Judith Radin Pdf
This title provides veterinary students and non-specialist with a case study base workbook which serves as a guide to effective use and interpretation of clinical chemistry laboratory methods in domestic animals. There are over 100 case studies involving real patients and findings in dogs, cats, horses, lamas, alpacas, pot belled pigs and ferrets. Case studies consist of patient history, physical examination findings, and clinicopthologic data such as CBC, urinalysis, cytology or fluid analysis. A summary is given for each patient that includes a description of follow up tests and response to treatment. Multiple cases of common diseases are included to illustrate the variety of clinciopathologic findings with the same diagnosis depending on individual patient factors. Diagnostic dilemmas in which different diseases may present with similar clinical signs and laboratory data are also included. Published by Teton New Media in the USA and distributed by Manson Publishing outside of North America.
By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and
A Toxicologist's Guide to Clinical Pathology in Animals by John E. Whalan Pdf
This guide provides an easy-to-use desk reference for diagnostic information on commonly used hematology, clinical chemistry and urinalysis parameters. Additional reference materials are provided as an aid in evaluating clinical pathology data. For many toxicologists, the evaluation of hematology, clinical chemistry and urinalysis data can be the most challenging aspect of animal toxicity studies. In a typical toxicity study, dozens of parameters are measured several times over the course of the study. There may be hundreds of data points, each of which needs to be considered. A Toxicologist’s Guide to Clinical Pathology in Animals will serve as an essential primer for toxicologists in training and in industry as well as for researchers and professionals in a veterinary practice or a laboratory.
Veterinary Hematology and Clinical Chemistry by Mary Anna Thrall Pdf
This reference on veterinary haematology and clinical chemistry is designed to be both comprehensive and practical. From basic principles and laboratory techniques to diagnostic evaluation, readers will find equally concise and clear coverage of both haematology and clinical chemistry for many domestic and exotic species. It also features numerous four-colour and black-and-white illustrations, coverage of avian and exotic haematology and an extensive use of case studies.
Manual of Veterinary Clinical Chemistry by Leslie C. Sharkey,Judith Radin Pdf
This case study based workbook provides veterinary students and non-specialist with a guide to effective use and interpretation of clinical chemistry laboratory methods in domestic animals. The 100+ case studies involve real patients and findings in dogs, cats, horses, lamas, alpacas, pot belled pigs and ferrets. These consist of patient history, physical examination findings, and clinicopthologic data such as CBC, urinalysis, cytology or fluid analysis. A summary is given for each patient that includes a description of follow up tests and response to treatment. Multiple cases of common diseases illustrate the variety of clinciopathologic findings with the same diagnosis depending on individual patient factors. Diagnostic dilemmas in which different diseases may present with similar clinical signs and laboratory data are also included. Published by Teton New Media in the USA and distributed by CRC Press outside of North America.
Clinical Biochemistry of Domestic Animals by J. J. Kaneko,C. E. Cornelius Pdf
Clinical Biochemistry of Domestic Animals, Second Edition, Volume I, is a major revision of the first edition prompted by the marked expansion of knowledge in the clinical biochemistry of animals. In keeping with this expansion of knowledge, this edition is comprised of two volumes. Chapters on the pancreas, thyroid, and pituitary-adrenal systems have been separated and entirely rewritten. Completely new chapters on muscle metabolism, iron metabolism, blood clotting, and gastrointestinal function have been added. All the chapters of the first edition have been revised with pertinent new information, and many have been completely rewritten. This volume contains 10 chapters and opens with a discussion of carbohydrate metabolism and associated disorders. Separate chapters follow on lipid metabolism, plasma proteins, and porphyrins. Subsequent chapters deal with liver, pancreatic, and thyroid functions; the role of the pituitary and adrenal glands in health and disease; the function of calcium, inorganic phosphorus, and magnesium metabolism in health and disease; and iron metabolism.
10+ Years of Updates Since First Edition Newcomers to the animal clinical chemistry and toxicology fields quickly find that the same rules of human medicine do not always apply. Following in the footsteps of its standard-setting first edition, Animal Clinical Chemistry: A Practical Handbook for Toxicologists and Biomedical Researchers, Second Edition collates information widely dispersed in journals and book chapters, focusing on the most relevant literature to experimental toxicology and its distinction from human medicine. Expands Discussion of Troponins, Lipids, and Electrolytes In addition to tests recommended by regulatory authorities, this globally relevant resource includes information about clinical chemistry tests as well as hepato-, nephro-, cardio-, and endocrine toxicity. It also covers pre-analytical and analytical variables, which play a far more important role with interpreting data from animal studies as compared to human studies when variables can be well controlled with less physiological effect. Furthermore, this edition takes its discussion of biomarkers to the next level, exploring newer and related investigations, such as metabolomics/NMR and multiplex technology. Under the editorial guidance of G.O. Evans, a recognized field authority, the book presents background information on the selection and application of biochemical tests in preclinical safety assessment studies. It also assesses specific organ toxicity, such as in the liver, kidney, and thyroid, along with regulatory requirements and statistical approaches. Careful to avoid delving into overly complex detail, this text is a comprehensive, practical reference ideal for new entrants to the field. However, its broad scope and depth also make it suitable for more seasoned scientists and toxicologists.
Small Animal Clinical Diagnosis by Laboratory Methods - E-Book by Michael D. Willard,Harold Tvedten Pdf
A quick guide to appropriately selecting and interpreting laboratory tests, Small Animal Clinical Diagnosis by Laboratory Methods, 5th Edition helps you utilize your in-house lab or your specialty reference lab to efficiently make accurate diagnoses without running a plethora of unnecessary and low-yield tests. It provides answers to commonly asked questions relating to laboratory tests, and solutions to frequently encountered problems in small animal diagnosis. For easy reference, information is provided by clinical presentation and abnormalities, and includes hundreds of tables, boxes, key points, and algorithms. This edition, now in full color, is updated with the latest advances in laboratory testing methods and diagnostic problem solving. Written by noted educators Dr. Michael Willard and Dr. Harold Tvedten, this book may be used as an on-the-spot guide to specific problems or conditions as well as a reference for more detailed research on difficult cases. Concise discussions address laboratory approaches to various disorders, possible conclusions from various test results, artifacts and errors in diagnoses, and interpretations leading to various diagnoses. Hundreds of tables, boxes, algorithms, and key points offer at-a-glance information including cautions, common pitfalls, and helpful "pearls," and lead to proper differential and clinical diagnostic decision making. Note boxes identify key considerations in correlating clinical signs with test data for accurate diagnoses, highlight safety precautions, and offer helpful tips for sample preparation and interpretation. Chapters on laboratory diagnostic toxicology and therapeutic drug monitoring help in handling potentially fatal poisonings and other special situations. Expert editors and contributors provide clinical knowledge and successful diagnostic problem-solving solutions. A practical appendix lists referral laboratories that may be contacted for certain diseases, and reference values with the normal or expected range for coagulation, hematology, and more. Updated coverage integrates the newest advances in testing methods and diagnostic problem solving. Full-color photos and schematic drawings are placed adjacent to related text, and accurately depict diagnostic features on microscopic slide preparations as well as test procedures and techniques.
Veterinary Laboratory Medicine by Morag G. Kerr Pdf
Veterinary Laboratory Medicine covers all aspects of basic clinical biochemistry and haematology, and includes test-by-test interpretation of laboratory results. Information is provided on sampling techniques, the selection and use of an external laboratory, as well as near-patient testing and the practice laboratory. Also included are step-by-step instructions for most commonly used point-of-care tests, a guide to the evaluation of instruments for in-practice use, and a detailed explanation of the principles of impedance counting and photometric analysis. The book will be ideal for practitioners who require a guide to laboratory work, and for veterinary students studying laboratory medicine and clinical pathology. The second edition has been fully updated to reflect advances in diagnostic techniques, and includes new chapters on diagnostic endocrinology and feline virus testing as well as a much expanded chapter on diagnostic profiling and pattern recognition.
By presenting background information on the selection and application of biochemical tests in safety assessment studies, this text seeks to provide a basis for improving the knowledge required to interpret data from toxicological studies. In addition to chapters which discuss the assessment of specific organ toxicity (such as the liver, kidney and thyroid), the book also covers pre-analytical variables, regulatory requirements and statistical approaches, and highlights some of the major differences between man and different laboratory animals. The editor and contributor are all members of the.
Author : Steven L. Stockham,Michael A. Scott Publisher : John Wiley & Sons Page : 948 pages File Size : 53,5 Mb Release : 2013-05-31 Category : Medical ISBN : 9781118686072
Fundamentals of Veterinary Clinical Pathology by Steven L. Stockham,Michael A. Scott Pdf
This book provides in-depth information about common clinical laboratory assays that are used to evaluate domestic mammals, including what assays measure, sample or assay conditions that affect results, and what results indicate about the physiologic or pathologic state of a patient. Whenever possible, diseases and conditions are grouped by common mechanisms or processes to promote a conceptual understanding of laboratory data that can be generally applied across many species. New to the second edition are additional disorders, diagnostic tests, illustrations, images, references, and pathophysiologic explanations. This text has proven valuable to students and veterinarians wanting a fundamental understanding of veterinary clinical pathology.
Textbook of Veterinary Physiological Chemistry by Larry R. Engelking Pdf
Bridging the gap between basic and clinical science concepts, the Textbook of Veterinary Physiological Chemistry, Third Edition offers broad coverage of biochemical principles for students and practitioners of veterinary medicine. The only recent biochemistry book written specifically for the veterinary field, this text covers cellular-level concepts related to whole-body physiologic processes in a reader-friendly, approachable manner. Each chapter is written in a succinct and concise style that includes an overview summary section, numerous illustrations for best comprehension of the subject matter, targeted learning objectives, and end of the chapter study questions to assess understanding. With new illustrations and an instructor website with updated PowerPoint images, the Textbook of Veterinary Physiological Chemistry, Third Edition, proves useful to students and lecturers from diverse educational backgrounds. Sectional exams and case studies, new to this edition, extend the breadth and depth of learning resources. Provides newly developed case studies that demonstrate practical application of concepts Presents comprehensive sectional exams for self-assessment Delivers instructor website with updated PowerPoint images and lecture slides to enhance teaching and learning Employs a succinct communication style in support of quick comprehension
Clinical Pathology and Laboratory Techniques for Veterinary Technicians by Amy L. MacNeill,Anne M. Barger Pdf
Clinical Pathology and Laboratory Techniques for Veterinary Technicians Up-to-date, practical reference book demonstrating laboratory procedures in dogs, cats, cattle and horses The newly revised and updated Second Edition of Clinical Pathology and Laboratory Techniques for Veterinary Technicians is an inclusive reference on laboratory procedures pertaining to small animals, horses, and cattle, providing information on hematology, hemostasis, clinical chemistry, urinalysis, parasitology, endocrine testing, and quality assurance. The text clarifies ‘how-to’ information while also discussing the importance of ‘why’ laboratory procedures are performed in a particular way, enabling readers to gain true understanding of the topics discussed. To aid in reader comprehension, high-quality photographs labeled with magnification and stain information, which clearly depict cellular morphology, inclusions, and infectious organisms, are included throughout each chapter. The text also offers key objectives, technician tip boxes, case examples, and a glossary of key terms, along with a companion website that provides instructor questions, and an answer key to multiple choice questions in the book. Clinical Pathology and Laboratory Techniques for Veterinary Technicians includes information on: Sample collection, handling, and quality assurance, to ensure laboratory test results are valid Hematology data collection techniques that may be used on a daily basis to evaluate the overall health of animal patients Clinical chemistry data to indicate organ function, covering how different chemicals measured in patient samples relate to the function of specific organs in the body In-house parasitology procedures, with important advances in molecular diagnostics have been made that improve the detection and identification of parasites Information about common endocrinopathies and submission of samples for endocrine testing. With complete coverage of the subject, Clinical Pathology and Laboratory Techniques for Veterinary Technicians is an essential resource for students enrolled in veterinary technology programs and veterinary colleges, and may be used as a textbook to guide and supplement information provided in both didactic and laboratory-based clinical pathology courses.
