Antibacterial Chemotherapy

Author : Roger Finch,Peter Davey,Mark H. Wilcox,William Irving
Publisher : OUP Oxford
Page : 409 pages
File Size : 54,9 Mb
Release : 2012-01-05
Category : Medical
ISBN : 9780191628658

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Antimicrobial Chemotherapy by Roger Finch,Peter Davey,Mark H. Wilcox,William Irving Pdf

Antimicrobial agents are essential for the treatment of life-threatening infections and for managing the burden of minor infections in the community. In addition, they play a key role in organ and bone marrow transplantation, cancer chemotherapy, artificial joint and heart valve surgery. Unlike other classes of medicines, they are vulnerable to resistance from mutations in target microorganisms, and their adverse effects may extend to other patients (increased risk of cross-infection). As a consequence, there is a constant requirement for new agents, as well as practices that ensure the continued effective prescribing of licensed agents. Public awareness and concerns about drug resistant organisms has led to widespread publicity and political action in the UK, Europe and worldwide. The control of drug resistance and the implementation of good prescribing practice are now legal requirements in the UK as a result of the UK Health Act (2008). These fundamental changes underscore the need for a thorough understanding of the advantages and risks associated with specific antibiotic choices. This sixth edition of Antimicrobial Chemotherapy continues to be a valuable resource for undergraduates and graduates requiring a thorough grounding in the scientific basis and clinical application of these drugs. This new edition is updated to include the most recently licensed agents, notably in the treatment of viral infections including HIV/AIDS, and contains new guidance on prescribing practice and infection control practices that limit the development and spread of resistant organisms.

Author : Peter Davey,Mark H. Wilcox,Will Irving,Guy Thwaites
Publisher : Oxford University Press, USA
Page : 431 pages
File Size : 43,6 Mb
Release : 2015
Category : Medical
ISBN : 9780199689774

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Antimicrobial Chemotherapy by Peter Davey,Mark H. Wilcox,Will Irving,Guy Thwaites Pdf

Preceded by: Antimicrobial chemotherapy / Roger Finch ... [et al.]. 6th ed. 2012.

Author : S.L. Dax
Publisher : Springer Science & Business Media
Page : 409 pages
File Size : 40,5 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789400900974

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Antibacterial Chemotherapeutic Agents by S.L. Dax Pdf

Over the past 50 years a wide variety of antibacterial substances have been discovered and synthesised, and their use in treating bacterial infection has been spectacularly successful. Today there are several general classes of antibacterial drugs, each having a well established set of uses, and together they form the mainstay of modern antibacterial chemotherapy. In search for new and improved agents, the pharmaceutical researcher needs to be well informed on many topics, including existing agents, their modes of action and pharmacology, and possible synthetic approaches. In this new book the author has brought together a wide range of information on the principal classes of antibacterial agents, and he covers, for each group, their history, mode of action, key structural features, synthesis and bacterial resistance. The result is a compact and concise overview of these very important classes of antibacterial agents.

Author : Sebastian Amyes
Publisher : Oxford University Press
Page : 93 pages
File Size : 46,8 Mb
Release : 2010-02-25
Category : Medical
ISBN : 9780199581368

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Antibacterial Chemotherapy by Sebastian Amyes Pdf

Part of the Oxford Infectious Disease Library, this pocketbook is designed to help medical trainees, general prescribers, healthcare workers and students to understand how antibiotics work, to demonstrate where they might be most appropriate, and to make clear the threat of antibiotic resistance.

Author : Roger G. Finch,David Greenwood,Richard J. Whitley,S. Ragnar Norrby
Publisher : Elsevier Health Sciences
Page : 913 pages
File Size : 43,6 Mb
Release : 2010-11-30
Category : Medical
ISBN : 9780702047657

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Antibiotic and Chemotherapy E-Book by Roger G. Finch,David Greenwood,Richard J. Whitley,S. Ragnar Norrby Pdf

Well-respected and widely regarded as the most comprehensive text in the field, Antibiotic and Chemotherapy, 9th Edition by Drs. Finch, Greenwood, Whitley, and Norrby, provides globally relevant coverage of all types of antimicrobial agents used in human medicine, including all antiviral, antiprotozoan and anthelminthic agents. Comprehensively updated to include new FDA and EMEA regulations, this edition keeps you current with brand-new information about antiretroviral agents and HIV, superficial and mucocutaneous myscoses and systemic infections, management of the immunocompromised patient, treatment of antimicrobial resistance, plus coverage of new anti-sepsis agents and host/microbe modulators. Reference is easy thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Offer the best possible care and information to your patients about the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Stay current with 21 new chapters including the latest information on superficial and mucocutaneous mycoses, systemic infections, anti-retroviral agents, and HIV. Get fresh perspectives and insights thanks to 21 newly-authored and extensively re-written chapters. Easily access information thanks to a unique 3-part structure covering general aspects of treatment; reviews of every agent; and details of treatments of particular infections. Apply the latest treatments for anti-microbial organisms such as MRSA, and multi-drug resistant forms of TB, malaria and gonorrhea. Keep up on the latest FDA and EMEA regulations.

Author : David Greenwood
Publisher : Unknown
Page : 499 pages
File Size : 51,9 Mb
Release : 2007
Category : Medical
ISBN : 9780198570165

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Antimicrobial Chemotherapy by David Greenwood Pdf

Instilling good prescribing habits in young doctors is essential for the benefit of patients and to preserve the value of the antibiotic revolution that altered medical practice in the second half of the twentieth century. These concerns underlie the approach taken in the new edition of this successful book. The text provides a comprehensive and up-to-date account of the principles of antimicrobial chemotherapy as an aid to informed, rational prescribing. Care is taken to address all aspects of antimicrobial drug use, including those specific to developed and developing countries of the world. The authors are international experts with a long standing interest in the role of education as a means of promoting an understanding of the benefits and limitations of antimicrobial chemotherapy in physicians, surgeons and other health care workers. The book offers a structured approach to the subject in four themed sections, each of several chapters. A historical introduction is followed by a section outlining the basic properties of antibacterial, antifungal, antiparasitic and antiviral (including antiretroviral) drugs.The next section explains the various facets of antimicrobial drug resistance - which threatens to undermine the continued efficacy of antimicrobial agents - and effective ways of countering the threat. Therapeutic use is covered in two sections: one introduces readers to the general principles that inform the rational prescribing of antimicrobial drugs; the second deals with practicalities of the use of antimicrobial agents in specific clinical conditions. The book ends with a description of the ways in which drugs are developed and marketed. There are extensive recommendations for further reading.

Author : Sebastian Amyes,Rex S Miles,Christopher J Thomson,Glenn Tillotson
Publisher : CRC Press
Page : 80 pages
File Size : 54,8 Mb
Release : 1996-01-01
Category : Medical
ISBN : 1853173894

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Antimicrobial Chemotherapy: Pocketbook by Sebastian Amyes,Rex S Miles,Christopher J Thomson,Glenn Tillotson Pdf

One of a series of pocketbooks designed to provide easily assimilable information on common medical issues. The concise texts are enhanced by tables and diagrams summarizing the essential information. This volume deals with antimicrobial therapy.

Author : David Greenwood
Publisher : Bailliere Tindall Limited
Page : 300 pages
File Size : 54,7 Mb
Release : 1983-06-01
Category : Medical
ISBN : 0721608051

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Antimicrobial Chemotherapy by David Greenwood Pdf

The essence of this book is to describe the basic properties of antibiotics and other antimicrobial agents and to discuss the principles underlying the rational use of antimicrobial agents in the management of infection. The aim is to encourage good prescribing habits in doctors throughout the world. After a short historical introduction, the text deals with the general properties of antimicrobial compounds of all kinds (antibacterial, antiviral, antifungal, antiprotozoal and anthelminthic agents); laboratory aspects of antimicrobial chemotherapy (including antibiotic interactions and use of the laboratory); resistance to antimicrobial agents (including mechanisms of resistance and the control of resistance);general principles of antibiotic usage (including pharmacokinetic issues, the prophylactic use of antibiotics, and special concerns of treatment of young children and the elderly) and the use of antimicrobial therapy in specific types of infection. There is a postscript on the development and marketing of antimicrobial agents.Reviews of previous editions: 'This reasonably priced volume is recommended without reservation for students and junior doctors, pharmacists, laboratory and other health care staff. I would also recommend it for microbiology departmental libraries.' Journal of Infection'...... well written, accomplishing the stated aims. All tables are essential to the discussion and easy to understand. American Journal of Pharmaceutical Education'The new edition retains the formula-winning layout of the first edition ... It is, to my knowledge, the only authoritative book written at this level, and it is required reading for students. Journal of Hospital Infection'The book covers an enormous amount of material, dealing as it does with antibacterial, antifungal, antiprotozoan and antiviral agents. Almost every aspect is covered ... the authors have in general managed to distil into the text the essential elements of the topics and ensure that the treatment is not superficial ... this paperback edition ... is very good value for money. It can truly be considered to cover, at a basic level, "all you need to know" about antimicrobial chemotherapy and can be highly recommended for junior clinical staff, pharmacy staff and junior biomedical scientists; their more senior colleagues will also find much of value in this new edition of Antimicrobial Chemotherapy.' British Journal of Biomedical Science'This updated textbook provides young doctors and students with the fundamental principles of antimicrobial chemotherapy. This third edition has been thoroughly revised and extensively rewritten. Drugs of Today'...excellently suited for trainee nurses, pharmacists and medical laboratory science officers ... Its short, but comprehensive covering of the topic make it highly advisable for everyone looking for basic knowledge of the properties and uses of antimicrobial drugs.' Infection'I think this is a useful reference textbook which undergraduate medical students will find beneficial in coming to grips with the principles of antimicrobial chemotherapy.' Journal of Medical Microbiology

Author : Lawrence Paul Garrod,Francis O'Grady
Publisher : Churchill Livingstone
Page : 542 pages
File Size : 42,8 Mb
Release : 1971
Category : Antibiotics
ISBN : UCAL:B4254299

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Antibiotic and Chemotherapy by Lawrence Paul Garrod,Francis O'Grady Pdf

Author : R.N. Grüneberg
Publisher : Springer Science & Business Media
Page : 223 pages
File Size : 49,7 Mb
Release : 2013-03-09
Category : Medical
ISBN : 9789401171946

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Antibiotics and Chemotherapy by R.N. Grüneberg Pdf

The purpose of this book is to provide reviews of various antibiotic topics which will be of interest to practising clinicians and to microbiologists. It is hoped that enough references have been provided to enable the enthusiast to immerse himself in the source literature. No attempt has been made to cover the whole field, which is well catered for in the numerous works on the subject. Rather, the intention has been to select a number of topics in which there has been a great deal of change in recent years, and to ask an appropriate authority to review the subject. Since I chose the topics, it may be supposed, quite correctly, that I have identified subjects in which I felt myself to require some postgraduate education. The process was something like the well known radio programme in which a castaway is allowed to select a number of gramophone records to take with him to a desert island. I hope that readers will share my interest in the contributions from a number of distinguished contributors to the field of antibiotic chemotherapeutic research. Although I have had the privilege of editing this volume it will be understood that the views expressed by the authors are their own and have not been the subject of editorial review. I am grateful to all the collaborators in this volume, and to the publishers, MTP Press, for their help, and for asking me to undertake the task. R. N.

Author : R. J. Schnitzer,Frank Hawking
Publisher : Elsevier
Page : 632 pages
File Size : 41,8 Mb
Release : 2013-09-12
Category : Medical
ISBN : 9781483273099

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Chemotherapy of Bacterial Infections by R. J. Schnitzer,Frank Hawking Pdf

Experimental Chemotherapy, Volume II: Chemotherapy of Bacterial Infections: Part I is devoted to the history, development, and progress of experimental chemotherapy of bacterial infections. The subject matter has been arranged according to particular groups of compounds, and in a few instances according to specific diseases. The emphasis of Volume II is placed on synthetic compounds. The literature is covered up to the latter part of 1963. It is hoped that this volume will be found useful by investigators and teachers concerned with experimental work on new substances and by physicians and veterinarians who use them. The book opens with a discussion of chemotherapy with antibacterial dyestuffs. This is followed by separate chapters on the mode of action of antibacterial substances such as sulfonamides, penicillins, and other antibiotics; the main lines on which research into antibacterial drugs has developed; and drug resistance for chemotherapy. Subsequent chapters deal with antibacterial chemotherapy with sulfonamides, the experimental pharmacology and toxicology of sulfonamides, the use of nitrofurans as chemotherapeutic agents, and antibacterial agents of limited action. The final chapters discuss experimental chemotherapy of tuberculosis and leprosy.

Author : Sebastian G. B. Amyes
Publisher : Unknown
Page : 80 pages
File Size : 43,7 Mb
Release : 2010
Category : Antibacterial agents
ISBN : 019174042X

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Antibacterial Chemotherapy by Sebastian G. B. Amyes Pdf

Although antibiotics are among the most widely used pharmaceuticals, they are also often inappropriately and over-prescribed. Indeed there are increasing predictions that unless we moderate our use of these drugs, bacterial resistance will eventually render them useless. As there are no serious contenders to take the place of antibiotics, including a failure to find new classes of these drugs, it is essential for modern medicine that their efficacy is preserved. Part of the Oxford Infectious Disease Library, this pocketbook is designed to help medical trainees, general prescribers, healthcare w.

Author : Rosaleen Anderson,Paul W. Groundwater,Adam Todd,Alan Worsley
Publisher : John Wiley & Sons
Page : 379 pages
File Size : 50,7 Mb
Release : 2012-05-30
Category : Science
ISBN : 9781118325445

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Antibacterial Agents by Rosaleen Anderson,Paul W. Groundwater,Adam Todd,Alan Worsley Pdf

Antibacterial agents act against bacterial infection either by killing the bacterium or by arresting its growth. They do this by targeting bacterial DNA and its associated processes, attacking bacterial metabolic processes including protein synthesis, or interfering with bacterial cell wall synthesis and function. Antibacterial Agents is an essential guide to this important class of chemotherapeutic drugs. Compounds are organised according to their target, which helps the reader understand the mechanism of action of these drugs and how resistance can arise. The book uses an integrated “lab-to-clinic” approach which covers drug discovery, source or synthesis, mode of action, mechanisms of resistance, clinical aspects (including links to current guidelines, significant drug interactions, cautions and contraindications), prodrugs and future improvements. Agents covered include: agents targeting DNA - quinolone, rifamycin, and nitroimidazole antibacterial agents agents targeting metabolic processes - sulfonamide antibacterial agents and trimethoprim agents targeting protein synthesis - aminoglycoside, macrolide and tetracycline antibiotics, chloramphenicol, and oxazolidinones agents targeting cell wall synthesis - β-Lactam and glycopeptide antibiotics, cycloserine, isonaizid, and daptomycin Antibacterial Agents will find a place on the bookshelves of students of pharmacy, pharmacology, pharmaceutical sciences, drug design/discovery, and medicinal chemistry, and as a bench reference for pharmacists and pharmaceutical researchers in academia and industry.

Author : Roger G. Finch
Publisher : Unknown
Page : 0 pages
File Size : 43,8 Mb
Release : 2003
Category : Medical
ISBN : 0443071292

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Antibiotic and Chemotherapy by Roger G. Finch Pdf

The completely revised and updated New Edition of this respected resource presents globally-relevant coverage of all types of antimicrobial agents used in human medicine, providing authoritative guidance on the principles and practice of antimicrobial chemotherapy. In addition to full coverage of every commonly used antibiotic agent, it includes complete coverage of all antiviral, antiprotozoan and anthelminthic agents. And, its unique 3-part structure makes it easy to locate information: Part I covers general aspects of treatment; Part II reviews every agent, including antimicrobial activity, pharmacokinetics, clinical use, and available preparations; Part III details the treatment of particular infections. Discusses the increasing problem of multi-drug resistance and the wide range of new antiviral therapies now available for the treatment of HIV and other viral infections. Reviews all of the new antimicrobial agents in detail. Features more clinically focused sections on Pharmacokinetics. Details new antifungal therapies, including voriconazole, liposomal, and amphotericin B. Presents new tables on major drug interactions, placental transfer, and concentrations of agents in breast milk. Features new sections on liver failure, drug development and licensing, and the implications of xenotransplantation. Presents expanded coverage of Quinolone as well as new antimalarial combination therapies. Offers cross-references to key web sites, for up-to-date information on treatment and drug resistance.

Author : Steeve Giguère,John F. Prescott,Patricia Dowling
Publisher : John Wiley & Sons
Page : 49 pages
File Size : 55,5 Mb
Release : 2013-07-25
Category : Medical
ISBN : 9781118675076

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Antimicrobial Therapy in Veterinary Medicine by Steeve Giguère,John F. Prescott,Patricia Dowling Pdf

The Fifth Edition of Antimicrobial Therapy in Veterinary Medicine, the most comprehensive reference available on veterinary antimicrobial drug use, has been thoroughly revised and updated to reflect the rapid advancements in the field of antimicrobial therapy. Encompassing all aspects of antimicrobial drug use in animals, the book provides detailed coverage of virtually all types of antimicrobials relevant to animal health. Now with a new chapter on antimicrobial therapy in zoo animals, Antimicrobial Therapy in Veterinary Medicine offers a wealth of invaluable information for appropriately prescribing antimicrobial therapies and shaping public policy. Divided into four sections covering general principles of antimicrobial therapy, classes of antimicrobial agents, special considerations, and antimicrobial drug use in multiple animal species, the text is enhanced by tables, diagrams, and photos. Antimicrobial Therapy in Veterinary Medicine is an essential resource for anyone concerned with the appropriate use of antimicrobial drugs, including veterinary practitioners, students, public health veterinarians, and industry and research scientists.