Antibiotic Policies

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Antibiotic Policies

Ian M. Gould,Jos W.M. van der Meer
Antibiotic Policies Book PDF

Author : Ian M. Gould,Jos W.M. van der Meer
Publisher : Springer Science & Business Media
Page : 758 pages
File Size : 40,5 Mb
Release : 2006-01-26
Category : Medical
ISBN : 9780387228525

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Antibiotic Policies by Ian M. Gould,Jos W.M. van der Meer Pdf

For 50 years, antibiotics have been dispensed like sweets. This must not be allowed to continue. This unique book assembles contributions from experts around the world concerned with responsible use of antibiotics and the consequences of overuse. For the first time, it provides up to the minute texts on both the theoretical aspects of antibiotic stewardship and the practical aspects of its implementation, with consideration of the key differences between developed and developing countries. All concerned with teaching, practice and administration of clinical medicine, surgery, pharmacy, public health, clinical pharmacology, microbiology, infectious diseases and clinical therapeutics will find Antibiotic Policies: Theory and Practice essential reading. Antibiotic use and resistance is not just the responsibility of specialists in the field but the responsibility of all doctors, pharmacists, nurses, healthcare administrators, patients and the general public.

Antibiotic Policies: Fighting Resistance

Ian M. Gould,Jos W.M. van der Meer
Antibiotic Policies Fighting Resistance Book PDF

Author : Ian M. Gould,Jos W.M. van der Meer
Publisher : Springer Science & Business Media
Page : 287 pages
File Size : 40,9 Mb
Release : 2007-08-19
Category : Medical
ISBN : 9780387708416

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Antibiotic Policies: Fighting Resistance by Ian M. Gould,Jos W.M. van der Meer Pdf

This volume examines many of the crucial issues of resistance in a clinical context, with an emphasis on MRSA; surely the greatest challenge to our antibiotic and infection control policies that modern health care systems have ever seen. Other chapters explore the psychology of prescribing, modern management techniques as an adjunct to antibiotic policies, and the less obvious downsides of antibiotic use.

Antibiotic Policies

Ian M. Gould,Jos W.M. van der Meer
Antibiotic Policies Book PDF

Author : Ian M. Gould,Jos W.M. van der Meer
Publisher : Springer Science & Business Media
Page : 209 pages
File Size : 41,7 Mb
Release : 2011-09-25
Category : Medical
ISBN : 1441917349

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Antibiotic Policies by Ian M. Gould,Jos W.M. van der Meer Pdf

The first book was on "Theory and Practice" of antibiotic stewardship in its broadest sense -the how to do it and the do's and don’ts. The second, on "Controlling resistance" was very much on the relationships between use and resistance and beginning to home in on the hospital as the main generator of resistance, but mainly looking at it from a disease/clinical perspective. The last 3 chapters on MRSA, ended where the 3rd book will take off. "Controlling HAI " will concentrate on specific MDR organisms highlighting their roles in the current pandemic of HAI and emphasizing that the big issue is not so much infection control but antibiotic control, in the same way that antibiotic over-reliance/ over-use has caused the problem in the first place. Up 'till now the emphasis for controlling MRSA, C diff and all the other MDROs has very much been on IC, which clearly isn't working. This book will gather all the evidence for the increasingly popular view that much more must be done in the area of antibiotic policies/ stewardship, especially when we are in danger of a "post antibiotic" era, due to a real shortage of new agents in the pipeline.

Extending the Cure

Ramanan Professor Laxminarayan,Anup Professor Malani,David Professor Howard,David L. Professor Smith
Extending the Cure Book PDF

Author : Ramanan Professor Laxminarayan,Anup Professor Malani,David Professor Howard,David L. Professor Smith
Publisher : Routledge
Page : 194 pages
File Size : 48,7 Mb
Release : 2010-09-30
Category : Medical
ISBN : 9781136527593

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Extending the Cure by Ramanan Professor Laxminarayan,Anup Professor Malani,David Professor Howard,David L. Professor Smith Pdf

Our ability to treat common bacterial infections with antibiotics goes back only 65 years. However, the authors of this report make it clear that sustaining a supply of effective and affordable antibiotics cannot be without changes to the incentives facing patients, physicians, hospitals, insurers, and pharmaceutical manufacturers. In fact, increasing resistance to these drugs is already exacting a terrible price. Every day in the United States, approximately 172 men, women, and children die from infections caused by antibiotic-resistant bacteria in hospitals alone. Beyond those deaths, antibiotic resistance is costing billions of dollars through prolonged hospital stays and the need for doctors to resort to ever more costly drugs to use as substitute treatments. Extending the Cure presents the problem of antibiotic resistance as a conflict between individual decision makers and their short-term interest and the interest of society as a whole, in both present and future: The effort that doctors make to please each patient by prescribing a drug when it might not be properly indicated, poor monitoring of discharged patients to ensure that they do not transmit drug-resistant pathogens to other persons, excesses in the marketing of new antibiotics, and the broad overuse of antibiotics all contribute to the development and spread of antibiotic-resistant bacteria. The book explores a range of policy options that would encourage patients, health care providers, and managed care organizations to serve as more responsible stewards of existing antibiotics as well as proposals that would give pharmaceutical firms greater incentives to develop new antibiotics and avoid overselling. If the problem continues unaddressed, antibiotic resistance has the potential to derail the health care system and return us to a world where people of all ages routinely die from simple infections. As a basis for future research and a spur to a critically important dialogue, Extending the Cure is a fundamental first step in addressing this public health crisis. The Extending the Cure project is funded in part by the Robert Wood Johnson Foundation through its Pioneer Portfolio.

Antibiotic Resistance

Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Antibiotic Resistance Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 496 pages
File Size : 50,5 Mb
Release : 2011-01-10
Category : Medical
ISBN : 9780309156110

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Antibiotic Resistance by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotic Policies: Fighting Resistance

Ian M. Gould,Jos W.M. van der Meer
Antibiotic Policies Fighting Resistance Book PDF

Author : Ian M. Gould,Jos W.M. van der Meer
Publisher : Springer Science & Business Media
Page : 286 pages
File Size : 49,6 Mb
Release : 2007-09-12
Category : Medical
ISBN : 9780387708409

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Antibiotic Policies: Fighting Resistance by Ian M. Gould,Jos W.M. van der Meer Pdf

This volume examines many of the crucial issues of resistance in a clinical context, with an emphasis on MRSA; surely the greatest challenge to our antibiotic and infection control policies that modern health care systems have ever seen. Other chapters explore the psychology of prescribing, modern management techniques as an adjunct to antibiotic policies, and the less obvious downsides of antibiotic use.

Antibiotic Drug Resistance

José-Luis Capelo-Martínez,Gilberto Igrejas
Antibiotic Drug Resistance Book PDF

Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 40,5 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781119282525

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Antibiotic Drug Resistance by José-Luis Capelo-Martínez,Gilberto Igrejas Pdf

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Ethics and Drug Resistance: Collective Responsibility for Global Public Health

Euzebiusz Jamrozik,Michael Selgelid
Ethics and Drug Resistance Collective Responsibility for Global Public Health Book PDF

Author : Euzebiusz Jamrozik,Michael Selgelid
Publisher : Springer
Page : 448 pages
File Size : 48,7 Mb
Release : 2021-08-21
Category : Philosophy
ISBN : 303027876X

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Ethics and Drug Resistance: Collective Responsibility for Global Public Health by Euzebiusz Jamrozik,Michael Selgelid Pdf

This Open Access volume provides in-depth analysis of the wide range of ethical issues associated with drug-resistant infectious diseases. Antimicrobial resistance (AMR) is widely recognized to be one of the greatest threats to global public health in coming decades; and it has thus become a major topic of discussion among leading bioethicists and scholars from related disciplines including economics, epidemiology, law, and political theory. Topics covered in this volume include responsible use of antimicrobials; control of multi-resistant hospital-acquired infections; privacy and data collection; antibiotic use in childhood and at the end of life; agricultural and veterinary sources of resistance; resistant HIV, tuberculosis, and malaria; mandatory treatment; and trade-offs between current and future generations. As the first book focused on ethical issues associated with drug resistance, it makes a timely contribution to debates regarding practice and policy that are of crucial importance to global public health in the 21st century.

Antimicrobial Stewardship

Céline Pulcini,Onder Ergonul,Füsun Can,Bojana Beović
Antimicrobial Stewardship Book PDF

Author : Céline Pulcini,Onder Ergonul,Füsun Can,Bojana Beović
Publisher : Academic Press
Page : 394 pages
File Size : 42,7 Mb
Release : 2017-04-05
Category : Science
ISBN : 9780128134610

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Antimicrobial Stewardship by Céline Pulcini,Onder Ergonul,Füsun Can,Bojana Beović Pdf

Antimicrobial Stewardship (AMS), Volume Two includes the experience of ESGAP workshops and courses on antibiotic stewardship since 2012. It combines clinical and laboratory information about AMS, with a focus on human medicine. The ESCMID study group on antibiotic policies (ESGAP) is one of the most productive groups in the field, organizing courses and workshops. This book is an ideal tool for the participants of these workshops. With short chapters (around 1500 words) written on different topics, the authors insisted on the following points: A ‘hands on’, practical approach, tips to increase success, a description of the most common mistakes, a global picture (out- and inpatient settings, all countries) and a short list of 10-20 landmark references. Focuses on the most recent antimicrobial stewardship strategies Provides a detailed description of laboratory support Offers a balanced synthesis of basic and clinical sciences for each individual case, presenting clinical courses of the cases in parallel with the pathogenesis and detailed microbiological information for each infection Describes the prevalence and incidence of the global issues and current therapeutic approaches Presents the measures for infection control

Policies and Incentives for Promoting Innovation in Antibiotic Research

Elias Mossialos
Policies and Incentives for Promoting Innovation in Antibiotic Research Book PDF

Author : Elias Mossialos
Publisher : World Health Organization
Page : 236 pages
File Size : 48,9 Mb
Release : 2010
Category : Medical
ISBN : OSU:32435082131715

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Policies and Incentives for Promoting Innovation in Antibiotic Research by Elias Mossialos Pdf

High levels of pathogen resistance are rendering current antibiotics obsolete. Coupled with insufficient investment in discovering new treatments, multidrug-resistant infections are an increasingly urgent public health concern. To curb the growth of antibiotic resistance and prevent major morbidity and mortality from multidrug-resistant bacterial infections, the overuse of antibiotics must be addressed and research and development for antibiotics with novel mechanisms of action actively promoted. This requires appropriately designed incentives for health and regulatory systems, in addition to economic incentives to attract academic interest and industry investment. This book, commissioned by the Swedish Government from the European Observatory on Health Systems and Policies, analyzes many proposed policies and incentive mechanisms and sheds light on the key issues that will help policy-makers reach informed, concrete decisions on how to avert this potential public health crisis.

The Resistance Phenomenon in Microbes and Infectious Disease Vectors

Institute of Medicine,Board on Global Health,Forum on Emerging Infections
The Resistance Phenomenon in Microbes and Infectious Disease Vectors Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Emerging Infections
Publisher : National Academies Press
Page : 333 pages
File Size : 54,9 Mb
Release : 2003-03-26
Category : Medical
ISBN : 9780309168304

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The Resistance Phenomenon in Microbes and Infectious Disease Vectors by Institute of Medicine,Board on Global Health,Forum on Emerging Infections Pdf

The resistance topic is timely given current events. The emergence of mysterious new diseases, such as SARS, and the looming threat of bioterrorist attacks remind us of how vulnerable we can be to infectious agents. With advances in medical technologies, we have tamed many former microbial foes, yet with few new antimicrobial agents and vaccines in the pipeline, and rapidly increasing drug resistance among infectious microbes, we teeter on the brink of loosing the upperhand in our ongoing struggle against these foes, old and new. The Resistance Phenomenon in Microbes and Infectious Disease Vectors examines our understanding of the relationships among microbes, disease vectors, and human hosts, and explores possible new strategies for meeting the challenge of resistance.

Improving Food Safety Through a One Health Approach

Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Improving Food Safety Through a One Health Approach Book PDF

Author : Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publisher : National Academies Press
Page : 418 pages
File Size : 52,9 Mb
Release : 2012-09-10
Category : Medical
ISBN : 9780309259361

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Improving Food Safety Through a One Health Approach by Institute of Medicine,Board on Global Health,Forum on Microbial Threats Pdf

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

The Use of Drugs in Food Animals

National Research Council,Institute of Medicine,Food and Nutrition Board,Board on Agriculture,Committee on Drug Use in Food Animals,Panel on Animal Health, Food Safety, and Public Health
The Use of Drugs in Food Animals Book PDF

Author : National Research Council,Institute of Medicine,Food and Nutrition Board,Board on Agriculture,Committee on Drug Use in Food Animals,Panel on Animal Health, Food Safety, and Public Health
Publisher : National Academies Press
Page : 276 pages
File Size : 40,8 Mb
Release : 1999-01-12
Category : Medical
ISBN : 9780309175777

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The Use of Drugs in Food Animals by National Research Council,Institute of Medicine,Food and Nutrition Board,Board on Agriculture,Committee on Drug Use in Food Animals,Panel on Animal Health, Food Safety, and Public Health Pdf

The use of drugs in food animal production has resulted in benefits throughout the food industry; however, their use has also raised public health safety concerns. The Use of Drugs in Food Animals provides an overview of why and how drugs are used in the major food-producing animal industriesâ€"poultry, dairy, beef, swine, and aquaculture. The volume discusses the prevalence of human pathogens in foods of animal origin. It also addresses the transfer of resistance in animal microbes to human pathogens and the resulting risk of human disease. The committee offers analysis and insight into these areas: Monitoring of drug residues. The book provides a brief overview of how the FDA and USDA monitor drug residues in foods of animal origin and describes quality assurance programs initiated by the poultry, dairy, beef, and swine industries. Antibiotic resistance. The committee reports what is known about this controversial problem and its potential effect on human health. The volume also looks at how drug use may be minimized with new approaches in genetics, nutrition, and animal management.

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses

OECD,World Health Organization
Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses Book PDF

Author : OECD,World Health Organization
Publisher : OECD Publishing
Page : 250 pages
File Size : 43,7 Mb
Release : 2020-04-01
Category : Electronic
ISBN : 9781108864121

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Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses by OECD,World Health Organization Pdf

Antimicrobial resistance (AMR) is a biological mechanism whereby a microorganism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognized response to AMR advocates for a ‘One Health’ approach, which requires policies to be developed and implemented across human, animal, and environmental health.

Antibiotic Discovery and Development

Thomas J. Dougherty,Michael J. Pucci
Antibiotic Discovery and Development Book PDF

Author : Thomas J. Dougherty,Michael J. Pucci
Publisher : Springer Science & Business Media
Page : 1119 pages
File Size : 54,8 Mb
Release : 2011-12-18
Category : Medical
ISBN : 9781461414001

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Antibiotic Discovery and Development by Thomas J. Dougherty,Michael J. Pucci Pdf

This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.