Antiepileptic Drugs

Author : Francesco Pisani
Publisher : Elsevier Publishing Company
Page : 216 pages
File Size : 43,5 Mb
Release : 1991
Category : Medical
ISBN : UOM:39015024821962

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New Antiepileptic Drugs by Francesco Pisani Pdf

The pharmacological fight against epilepsy began many centuries ago when Hippocrates discovered that the cause of epilepsy is natural, as opposed to supernatural and, as a consequence, must be treated with a natural remedy. Even though science has significantly progressed since that era, the challenge to find remedies for epilepsy is ever present. The aim of this particular volume is to offer an up-to-date review of the most recent advances in antiepileptic drug development, considered from various viewpoints: (i) general, by taking into account the size of refractory epilepsy and its related problems; (ii) experimental, by exploring the mechanisms of epileptogenesis and the possiblility of influencing it through drugs, and (iii) clinical, by describing the results obtained with compounds currently at an advanced stage of testing.

Author : Philip Patsalos
Publisher : Springer Science & Business Media
Page : 464 pages
File Size : 40,7 Mb
Release : 2012-12-03
Category : Medical
ISBN : 9781447124344

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Antiepileptic Drug Interactions by Philip Patsalos Pdf

Antiepileptic Drug Interactions: A Clinical Guide, Second Edition provides a pocket-sized, systematic description of the most clinically relevant drug interactions that occur between AEDs and also between AEDs and non-AEDs. AEDs are presented alphabetically and by drug class in three sections for easy access: Drug interactions between AEDs; Drug interactions between AEDs and non-AEDs: Interactions affecting AEDs; and Drug interactions between AEDs and non-AEDs: Interactions affected by AEDs. Antiepileptic Drug Interactions: A Clinical Guide, Second Edition should help physicians make more rational choices when polytherapy regimens are indicated and should be of interest to all who treat patients with epilepsy: neurologists and neurosurgeons, trainees at all levels, general practitioners and epilepsy nurse specialists.

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 50,9 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Author : Simon Shorvon,Emilio Perucca,Jerome Engel, Jr.
Publisher : John Wiley & Sons
Page : 1072 pages
File Size : 53,8 Mb
Release : 2015-09-15
Category : Medical
ISBN : 9781118936986

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The Treatment of Epilepsy by Simon Shorvon,Emilio Perucca,Jerome Engel, Jr. Pdf

Highly Commended at the British Medical Association Book Awards 2016 The Treatment of Epilepsy, fourth edition, is a comprehensive reference and clinical guide to the pharmacological, medical and surgical options available in the treatment of epilepsy. The text is compiled by a group of internationally renowned editors and contributors and is now in full color and extensively illustrated The first two sections cover the background to, and principles of, treatment in different clinical situations Section three comprises a series of systematic reviews of contemporary drug therapy, devoting one chapter to each anti-epileptic drug and covering all clinically-relevant aspects Section four focuses on the surgical options, devoting individual chapters to each of the modalities of presurgical assessment and to each surgical operation or approach This 4th edition is extensively revised incorporating the many recent developments in therapy, and comprises 81 chapters from world experts from 18 countries

Author : Ali A. Asadi-Pooya,Michael R. Sperling
Publisher : Oxford University Press
Page : 299 pages
File Size : 42,7 Mb
Release : 2016
Category : Medical
ISBN : 9780190214968

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Antiepileptic Drugs by Ali A. Asadi-Pooya,Michael R. Sperling Pdf

This concise handbook provides practical, up-to-date clinical guidance on effective selection, prescription, and usage of antiepileptic drugs for patients with epilepsy in various medical conditions and in a variety of clinical contexts. This text discusses choosing drugs when faced with various medical comorbidities; how to correctly prescribe, titrate, and taper drugs; how to monitor drug efficacy and side effects; how to diagnose and manage toxicity; how antiepileptic drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include · A brief formal discussion of the basic pharmacology of each antiepileptic drug, with an emphasis on how to select and use anti-epileptic drugs in a variety of clinical contexts. · Discussions of antiepileptic drugs approved for epilepsy since 2009. · New research about already existing antiepileptic drugs. · References for further reading that are oriented toward utility in clinical practice. Antiepileptic Drugs: A Clinician's Manual fills an unmet need as a practical, patient-oriented reference and leads to improved patient care. Supported by practical, clinical knowledge and experience, this is the perfect guide for physicians looking to ensure safe practices in antiepileptic drug therapy.

Author : L. Beani,Dieter Janz
Publisher : Springer
Page : 904 pages
File Size : 46,6 Mb
Release : 1985
Category : Anticonvulsants
ISBN : UOM:39015007132601

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Antiepileptic Drugs by L. Beani,Dieter Janz Pdf

Author : M J Eadie,F Vajda
Publisher : Unknown
Page : 676 pages
File Size : 41,8 Mb
Release : 1999-04-16
Category : Electronic
ISBN : 3642600735

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Antiepileptic Drugs by M J Eadie,F Vajda Pdf

This volume provides up to date knowledge of the pharmacologies of the various antiepileptic drugs, especially those which have become available since 1984 when the previous edition (Handbook of Experimental Pharmacology, Volume 74: Antiepileptic Drugs, edited by H.-H. Frey and D. Janz) appeared. The data concerning the individual drugs are presented in a structured format. There are also chapters providing overviews of subjects such as the neurophysiological and biochemical mechanisms of action of the antiepileptic drugs, their testing in experimental animals, their interactions, their clinical use, and the new agents currently in the course of development.

Author : H. Steve White,Jong M. Rho
Publisher : Professional Communications
Page : 168 pages
File Size : 49,9 Mb
Release : 2010
Category : Medical
ISBN : 9781932610666

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Mechanisms of Action of Antiepileptic Drugs by H. Steve White,Jong M. Rho Pdf

Mechanisms of Action of Antiepileptic Drugs provides a review of all of the mechanisms of action (MOA) of each of the classes of antiepileptic drugs. This is a graphic-intensive text, with detailed illustrations of the various MOA. Introductory and concluding chapters discuss the relevance of MOA to clinical practice. A brief review of neurophysiology of normal and epileptic neurons is followed by individual chapters dedicated to the MOA of each class of antiepileptic drug.

Author : Jerzy Majkowski
Publisher : Cambridge University Press
Page : 530 pages
File Size : 51,5 Mb
Release : 2005-05-26
Category : Medical
ISBN : 052182219X

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Antiepileptic Drugs by Jerzy Majkowski Pdf

This book reviews the use of antiepileptic drugs focusing on the interactions between these drugs and between antiepileptics and other drugs. These interactions can be beneficial or can cause harm. The aim of this book is to increase awareness of the possible impact of combination pharmacotherapies. Pharmacokinetic and pharmacodynamic interactions are discussed supported by clinical and experimental data. The book consists of five sections covering the general concepts and advantages of combination therapies, the principles of drug interactions, the mechanisms of interactions, drug interactions in specific populations or in patients with co-morbid health conditions, and concludes with a look at the future directions for this field of research. The book will be of interest to all who prescribe antiepileptics to epileptic and non-epileptic patients, including epileptologists, neurologists, neuro-pediatricians, psychiatrists and general practitioners.

Author : Chrysostomos P. Panayiotopoulos
Publisher : Springer
Page : 570 pages
File Size : 44,7 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015062497741

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The Epilepsies by Chrysostomos P. Panayiotopoulos Pdf

This book gives an exhaustive account of the classification and management of epileptic disorders. It provides clear didactic guidance on the diagnosis and treatment of epileptic syndromes and seizures through thirteen chapters, complemented by a pharmacopoeia and CD ROM of video-EEGs.

Author : Arun Garg,Ram Atma Bansal
Publisher : Jaypee Brothers Medical Publishers
Page : 173 pages
File Size : 52,6 Mb
Release : 2020-03-31
Category : Medical
ISBN : 9789388958240

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Antiepileptic Drugs by Arun Garg,Ram Atma Bansal Pdf

Epilepsy is a common condition that affects the brain and causes frequent seizures. Seizures are bursts of electrical activity in the brain that temporarily affect how it works. They can cause a wide range of symptoms. Epilepsy can start at any age, but usually starts either in childhood or in people over 60. This book is a comprehensive guide to the appropriate selection and usage of antiepileptic drugs (AEDs). Beginning with historical and pharmacological aspects, the next chapters examine older, newer and third generation antiepileptic drugs, highlighting key differences between each type. The following sections cover the use of AEDs amongst different sectors of the population – children, geriatrics and those with comorbidities such as pregnancy and systemic disorders. The book concludes with discussion on drug monitoring and management of status epilepticus (a single epileptic seizure lasting more than five minutes or two or more seizures within a five-minute period without the person returning to normal between them. It is a life-threatening medical emergency particularly if treatment is delayed). Presented in a step by step format, the text is further enhanced by algorithms, tables and diagrams to assist understanding. Key points Comprehensive guide to selection and usage of antiepileptic drugs (AEDs) Covers AED use amongst different sectors of the population Compares older, newer and third generation AEDs Highly illustrated with algorithms, tables and diagrams

Author : Gonzalo Alarcón,Antonio Valentín
Publisher : Cambridge University Press
Page : 641 pages
File Size : 54,6 Mb
Release : 2012-04-26
Category : Medical
ISBN : 9780521691581

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Introduction to Epilepsy by Gonzalo Alarcón,Antonio Valentín Pdf

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.

Author : Anonim
Publisher : Academic Press
Page : 1853 pages
File Size : 51,5 Mb
Release : 2009-05-27
Category : Medical
ISBN : 9780123739612

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Encyclopedia of Basic Epilepsy Research by Anonim Pdf

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research

Author : Andrea E. Cavanna
Publisher : Oxford University Press
Page : 181 pages
File Size : 44,9 Mb
Release : 2018
Category : Medical
ISBN : 9780198791577

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Behavioural Neurology of Anti-Epileptic Drugs by Andrea E. Cavanna Pdf

With up-to-date content and a practical approach, Behavioural Neurology of Antiepileptic Drugs: A Practical Guide is an invaluable resource for busy clinicians wanting to enhance their understanding of antiepileptic drugs and their behavioural effects.

Author : Luisa Rocha,Esper A. Cavalheiro
Publisher : Springer Science & Business Media
Page : 333 pages
File Size : 50,5 Mb
Release : 2014-07-08
Category : Medical
ISBN : 9781461464648

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Pharmacoresistance in Epilepsy by Luisa Rocha,Esper A. Cavalheiro Pdf

Although more than 10 new antiepileptic drugs have been developed in the past decade, epilepsy remains resistant to drug therapy in about one third of patients, many of whom struggle with the disease their entire lives. Managing these patients is a challenge and requires a structured multidisciplinary approach. The book includes chapters on all issues related to pharmacoresistance in epilepsy and describes recent developments in the pathogenesis and treatment of this disorder. It addresses abnormalities in inhibitory mechanisms, epilepsy-related changes to the immune system, development of pharmacoresistance caused by chronic exposure to antiepileptic drugs, and novel therapeutic strategies for preventing or slowing down the progression of the disease. Clinicians and basic scientists alike will find up-to-date information on the development of pharmacoesistance, as well as reviews of mechanisms associated with epilepsy that may help them consider novel strategies for preventing the development of pharmacoresistance in the first place. The book also features information on new therapeutic strategies for control of epilepsy, such as transcutaneous electrical stimulation and virtual screening of new antiepileptic drugs. Pharmacoresistance in Epilepsy: From Genes and Molecules to Promising Therapies is useful to anyone working in the field, whether they’re studying epilepsy in the lab or treating it in a doctor’s office.”