Antisense Elements Genetics Research Focus

Author : A. G. Hernandes
Publisher : Nova Publishers
Page : 246 pages
File Size : 47,6 Mb
Release : 2007
Category : Antisense RNA
ISBN : 1600214916

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Antisense Elements (genetics) Research Focus by A. G. Hernandes Pdf

Antisense molecules interact with complementary strands of nucleic acids, modifying expression of genes. Some regions within a double strand of DNA code for genes, which are usually instructions specifying the order of amino acids in a protein along with regulatory sequences, splicing sites, non-coding introns and other complicating details. For a cell to use this information, one strand of the DNA serves as a template for the synthesis of a complementary strand of RNA. The template DNA strand is called the transcribed strand with antisense sequence and the mRNA transcript is said to be sense sequence (the complement of antisense). Because the DNA is double-stranded, the strand complementary to the antisense sequence is called non-transcribed strand and has the same sense sequence as the mRNA transcript (though T bases in DNA are substituted with U bases in RNA). This book presents important new research from around the world in this field.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 46,5 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Rebecca N. Campbell
Publisher : Nova Publishers
Page : 354 pages
File Size : 47,5 Mb
Release : 2008
Category : Cancer
ISBN : 1600219705

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Gene Therapy and Cancer Research Focus by Rebecca N. Campbell Pdf

Genes, which are carried on chromosomes, are the basic physical and functional units of heredity. Genes are specific sequences of bases that encode instructions on how to make proteins. Although genes get a lot of attention, it's the proteins that perform most life functions and even make up the majority of cellular structures. When genes are altered so that the encoded proteins are unable to carry out their normal functions, genetic disorders can result. Gene therapy is an experimental treatment that involves introducing genetic material into a person's cells to fight disease. Gene therapy is being studied in clinical trials for many different types of cancer and for numerous other diseases. The volume presents significant new research results in this promising field.

Author : Robert E. Farrell Jr.
Publisher : Elsevier
Page : 794 pages
File Size : 54,7 Mb
Release : 2010-07-22
Category : Science
ISBN : 9780080454764

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RNA Methodologies by Robert E. Farrell Jr. Pdf

This laboratory guide represents a growing collection of tried, tested and optimized laboratory protocols for the isolation and characterization of eukaryotic RNA, with lesser emphasis on the characterization of prokaryotic transcripts. Collectively the chapters work together to embellish the RNA story, each presenting clear take-home lessons, liberally incorporating flow charts, tables and graphs to facilitate learning and assist in the planning and implementation phases of a project. RNA Methodologies, 3rd edition includes approximately 30% new material, including chapters on the more recent technologies of RNA interference including: RNAi; Microarrays; Bioinformatics. It also includes new sections on: new and improved RT-PCR techniques; innovative 5’ and 3’ RACE techniques; subtractive PCR methods; methods for improving cDNA synthesis. * Author is a well-recognized expert in the field of RNA experimentation and founded Exon-Intron, a well-known biotechnology educational workshop center * Includes classic and contemporary techniques * Incorporates flow charts, tables, and graphs to facilitate learning and assist in the planning phases of projects

Author : Olga N. Ozoline,Klaus Neuhaus
Publisher : Frontiers Media SA
Page : 164 pages
File Size : 51,9 Mb
Release : 2022-01-05
Category : Science
ISBN : 9782889719631

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Small RNAs as a Diverse Toolkit of Bacteria by Olga N. Ozoline,Klaus Neuhaus Pdf

Author : Anonim
Publisher : Academic Press
Page : 379 pages
File Size : 41,6 Mb
Release : 1994-09-29
Category : Science
ISBN : 0080863361

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Progress in Nucleic Acid Research and Molecular Biology by Anonim Pdf

Provides a forum for discussion of new discoveries, approaches, and ideas in molecular biology Includes contributions from leaders in their fields Abundantly referenced

Author : Anonim
Publisher : Academic Press
Page : 527 pages
File Size : 42,7 Mb
Release : 1997-08-12
Category : Science
ISBN : 9780080581323

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Gene Therapy by Anonim Pdf

Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. Volume 40, GeneTherapy, features important new research on gene transfers and therapy in the herpes simplex virus, anti-tumor immunity, steroid receptors, cystic fibroses, and more. Key Features* It provides an excellent overview on a series of topics on gene therapy for the serious investigator

Author : Paul L. Bartel,Stanley Fields
Publisher : Oxford University Press, USA
Page : 362 pages
File Size : 42,6 Mb
Release : 1997
Category : Carrier proteins
ISBN : 0195109384

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The Yeast Two-hybrid System by Paul L. Bartel,Stanley Fields Pdf

This volume, part of the Advances in Molecular Biology series, presents work by pioneers in the field and is the first publication devoted solely to the yeast two-hybrid system. It includes detailed protocols, practical advice on troubleshooting, and suggestions for future development. In addition, it illustrates how to construct an activation domain hybrid library, how to identify mutations that disrupt an interaction, and how to use the system in mammalian cells. Many of the contributors have developed new applications and variations of the technique.

Author : L.E. Feinendegen,W.W. Shreeve,W.C. Eckelman,Yong Whee Bahk,H.N. Jr. Wagner
Publisher : Springer Science & Business Media
Page : 795 pages
File Size : 52,6 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642555398

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Molecular Nuclear Medicine by L.E. Feinendegen,W.W. Shreeve,W.C. Eckelman,Yong Whee Bahk,H.N. Jr. Wagner Pdf

Biochemical transparency of the human body is at the doorstep of advanced technology. Toward this goal the book describes relevant isotopic tracer techniques of nuclear medicine. It deals with quantitatively measuring in vivo biochemical reactions as they occur within homeostatic circuits under control by genes and protein interactions. The text indicates how nuclear medicine can aid clinical researchers and practitioners, human geneticists and pharmacologists in understanding (and affecting) gene-phenotype relationships. Experts give background, techniques and examples in an interdisciplinary approach to regional imaging and in vitro analyses of biochemical reactions.

Author : Peter M. Gresshoff
Publisher : CRC Press
Page : 256 pages
File Size : 41,7 Mb
Release : 2020-09-10
Category : Science
ISBN : 9781000099256

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Plant Genome Analysis by Peter M. Gresshoff Pdf

Plant Genome Analysis presents outstanding analyses of technologies, as well as explanations of molecular technology as it pertains to agriculture. Advances in genome analysis, including DNA amplification (DAF and RAPD) markers, RFLPs, and microsatellites are reviewed by accomplished scientists, many of whom are the developers of the technique. Articles by patent lawyers experienced in plant biotechnology present the legal viewpoint. Chapters focus on special elements of genome analysis, such as the: use of antisense technology investigation of telomeres production of plant YACs importance of cell cycle genes in plants. Other chapters focus on specialized topics of genome analysis. These include a description of antisense technology in the study of photosynthesis and a comprehensive review of the characterization and isolation of plant telomere, including their use in varietal discrimination. A detailed anaysis of cytoplasmic male sterility in the french bean that focuses on the mitochondrial genome is described. The book provides a chapter on the production of yeast artificial chromosomes (YACs) carrying soybean DNA. Genes of the cell cycle in plants and their importance in developmental processes are presented, as well as detailed chapters on the molecular mapping of trees (apples and pines), and nodulation-related genes in legumes. A comprehensive index and a complete glossary are included.

Author : Anonim
Publisher : Unknown
Page : 820 pages
File Size : 46,6 Mb
Release : 2009
Category : Bibliographical literature
ISBN : STANFORD:36105129062332

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Bibliographic Index by Anonim Pdf

Author : National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation
Publisher : National Academies Press
Page : 188 pages
File Size : 50,6 Mb
Release : 2006-03-09
Category : Science
ISBN : 9780309164887

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Reaping the Benefits of Genomic and Proteomic Research by National Research Council,Policy and Global Affairs,Committee on Science, Technology, and Law,Board on Science, Technology, and Economic Policy,Committee on Intellectual Property Rights in Genomic and Protein Research and Innovation Pdf

The patenting and licensing of human genetic material and proteins represents an extension of intellectual property (IP) rights to naturally occurring biological material and scientific information, much of it well upstream of drugs and other disease therapies. This report concludes that IP restrictions rarely impose significant burdens on biomedical research, but there are reasons to be apprehensive about their future impact on scientific advances in this area. The report recommends 13 actions that policy-makers, courts, universities, and health and patent officials should take to prevent the increasingly complex web of IP protections from getting in the way of potential breakthroughs in genomic and proteomic research. It endorses the National Institutes of Health guidelines for technology licensing, data sharing, and research material exchanges and says that oversight of compliance should be strengthened. It recommends enactment of a statutory exception from infringement liability for research on a patented invention and raising the bar somewhat to qualify for a patent on upstream research discoveries in biotechnology. With respect to genetic diagnostic tests to detect patient mutations associated with certain diseases, the report urges patent holders to allow others to perform the tests for purposes of verifying the results.

Author : Bruce R. Korf,Mira B. Irons
Publisher : John Wiley & Sons
Page : 280 pages
File Size : 48,8 Mb
Release : 2012-11-19
Category : Medical
ISBN : 9781118537664

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Human Genetics and Genomics by Bruce R. Korf,Mira B. Irons Pdf

This fourth edition of the best-selling textbook, Human Genetics and Genomics, clearly explains the key principles needed by medical and health sciences students, from the basis of molecular genetics, to clinical applications used in the treatment of both rare and common conditions. A newly expanded Part 1, Basic Principles of Human Genetics, focuses on introducing the reader to key concepts such as Mendelian principles, DNA replication and gene expression. Part 2, Genetics and Genomics in Medical Practice, uses case scenarios to help you engage with current genetic practice. Now featuring full-color diagrams, Human Genetics and Genomics has been rigorously updated to reflect today’s genetics teaching, and includes updated discussion of genetic risk assessment, “single gene” disorders and therapeutics. Key learning features include: Clinical snapshots to help relate science to practice ‘Hot topics’ boxes that focus on the latest developments in testing, assessment and treatment ‘Ethical issues’ boxes to prompt further thought and discussion on the implications of genetic developments ‘Sources of information’ boxes to assist with the practicalities of clinical research and information provision Self-assessment review questions in each chapter Accompanied by the Wiley E-Text digital edition (included in the price of the book), Human Genetics and Genomics is also fully supported by a suite of online resources at www.korfgenetics.com, including: Factsheets on 100 genetic disorders, ideal for study and exam preparation Interactive Multiple Choice Questions (MCQs) with feedback on all answers Links to online resources for further study Figures from the book available as PowerPoint slides, ideal for teaching purposes The perfect companion to the genetics component of both problem-based learning and integrated medical courses, Human Genetics and Genomics presents the ideal balance between the bio-molecular basis of genetics and clinical cases, and provides an invaluable overview for anyone wishing to engage with this fast-moving discipline.

Author : Guenther Witzany,Luis Villarreal
Publisher : Frontiers Media SA
Page : 179 pages
File Size : 40,7 Mb
Release : 2018-05-11
Category : Electronic
ISBN : 9782889454778

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Genome Invading RNA Networks by Guenther Witzany,Luis Villarreal Pdf

A new paradigmatic understanding of evolution, genetic novelty, code-generating, genome-formatting factors, infectious RNA Networks, viruses and other natural genetic content operators.

Author : National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology
Publisher : National Academies Press
Page : 348 pages
File Size : 51,7 Mb
Release : 2000-12-21
Category : Nature
ISBN : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment by National Research Council,Commission on Life Sciences,Board on Environmental Studies and Toxicology,Committee on Developmental Toxicology Pdf

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.