Apoptosis In Health And Disease Part B

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Apoptosis in Health and Disease - Part B

Rossen Donev
Apoptosis in Health and Disease Part B Book PDF

Author : Rossen Donev
Publisher : Academic Press
Page : 358 pages
File Size : 40,9 Mb
Release : 2021-06-02
Category : Science
ISBN : 9780323853187

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Apoptosis in Health and Disease - Part B by Rossen Donev Pdf

Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process. Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. Integrates experimental and computational methods for studying apoptosis in health and different diseases Includes strategies for identification of suitable therapeutic targets Discusses the design of treatments targeting key points in the apoptotic cascade

Apoptosis in Health and Disease - Part B

Rossen Donev
Apoptosis in Health and Disease Part B Book PDF

Author : Rossen Donev
Publisher : Academic Press
Page : 0 pages
File Size : 53,7 Mb
Release : 2021-06-03
Category : Science
ISBN : 032385317X

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Apoptosis in Health and Disease - Part B by Rossen Donev Pdf

Apoptosis in Health and Disease - Part B, Volume 126 in the Advances in Protein Chemistry and Structural Biology focuses on apoptotic responses in numerous conditions - from bacterial and parasite infections, to pathological states such as oxidative stress, pulmonary hypertension, and different cancer types, etc. In addition, the book provides therapeutic strategies for targeting apoptosis. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target the cell death process. Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. Vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases.

Apoptosis in Health and Disease

Martin Holcik,Eric C. LaCasse,Alex E. MacKenzie,Robert G. Korneluk
Apoptosis in Health and Disease Book PDF

Author : Martin Holcik,Eric C. LaCasse,Alex E. MacKenzie,Robert G. Korneluk
Publisher : Cambridge University Press
Page : 265 pages
File Size : 49,6 Mb
Release : 2012-01-26
Category : Medical
ISBN : 9780521159449

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Apoptosis in Health and Disease by Martin Holcik,Eric C. LaCasse,Alex E. MacKenzie,Robert G. Korneluk Pdf

A 2005 survey of the role of apoptosis in the pathogenesis of many significant human illnesses and injury states.

Cell Death Regulation in Health and Disease - Part B

Anonim
Cell Death Regulation in Health and Disease Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 232 pages
File Size : 50,9 Mb
Release : 2020-04-22
Category : Science
ISBN : 9780128199305

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Cell Death Regulation in Health and Disease - Part B by Anonim Pdf

Cell Death Regulation in Health and Disease - Part B, Volume 352, the latest release in the International Review of Cell and Molecular Biology, reviews and details current advances in cell and molecular biology. Chapters in this updated release include Regulation of cell death signaling in insects, Bcl-2 family proteins, Cell death signaling in prokaryotes, Parthanatos in neurodegenerative diseases, Cell death regulation in yeast, Mutual regulation of autophagy and necroptosis, Therapeutic inhibition of cell death by autophagy induction, and Necroptosis in neurodegenerative diseases. Provides a comprehensive collection of front-of-the line research in the field of cell death regulation Authored by established and active cell and molecular biologists drawn from international sources Presents only invited review articles, covering selected topics in many different organisms and disease settings

Apoptosis in Health and Disease - Part A

Rossen Donev
Apoptosis in Health and Disease Part A Book PDF

Author : Rossen Donev
Publisher : Academic Press
Page : 320 pages
File Size : 41,9 Mb
Release : 2021-04-28
Category : Science
ISBN : 9780323853163

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Apoptosis in Health and Disease - Part A by Rossen Donev Pdf

Apoptosis, or programmed cell death, is the mechanism by which cells die either physiologically or pathologically. A vast research in apoptosis has advanced our understanding of basic physiological and pathological processes occurring in cells, organs and organisms, and its role in a number of diseases. These new advanced understandings are playing a major influence in drug discovery and the introduction of new therapies that target this cell death process. These two thematic volumes 125 and 126 of the Advances in Protein Chemistry and Structural Biology focus on apoptotic responses in numerous conditions - from bacterial and parasite infections to pathological states such as oxidative stress, pulmonary hypertension, different cancer types, etc. Finally, therapeutic strategies for targeting apoptosis are also discussed. Integrates experimental and computational methods for studying apoptosis in health and different diseases, strategies for identification of suitable therapeutic targets, and design of treatments targeting key points in apoptotic cascade

Cell Death Regulation in Health and Disease - Part C

Anonim
Cell Death Regulation in Health and Disease Part C Book PDF

Author : Anonim
Publisher : Academic Press
Page : 298 pages
File Size : 53,5 Mb
Release : 2020-05-14
Category : Science
ISBN : 9780128201350

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Cell Death Regulation in Health and Disease - Part C by Anonim Pdf

Cell Death Regulation in Health and Disease - Part C, Volume 353 in the International Review of Cell and Molecular Biology series, reviews and details current advances in cell and molecular biology. The IRCMB series maintains the highest standard by publishing timely topics authored by prominent cell and molecular biologists, with this release covering Developmental and seasonal regulation of neural cell death in birds, Post-translational modifications in cell death regulation, The role of cell death in tissue regeneration and fibrosis, Crosstalk between the apoptosis and autophagy signaling pathways, IP3 receptor signal integration in cell death and survival decisions, and more. Provides a comprehensive collection of front-of-the line research in the field of cell death regulation Authored by established and active cell and molecular biologists drawn from international sources Includes only invited review articles, covering selected topics in many different organisms and disease settings

Inter-Organellar Ca2+ Signaling in Health and Disease - Part B

Anonim
Inter Organellar Ca2 Signaling in Health and Disease Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 46,5 Mb
Release : 2021-08-12
Category : Science
ISBN : 9780128240373

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Inter-Organellar Ca2+ Signaling in Health and Disease - Part B by Anonim Pdf

International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology. Publishes only invited review articles on selected topics Authored by established and active cell and molecular biologists and drawn from international sources Offers a wide range of perspectives on specific subjects

Biochemistry of Apoptosis and Autophagy

Lorrie A. Kirshenbaum
Biochemistry of Apoptosis and Autophagy Book PDF

Author : Lorrie A. Kirshenbaum
Publisher : Springer
Page : 0 pages
File Size : 45,6 Mb
Release : 2022-11-30
Category : Science
ISBN : 3030788016

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Biochemistry of Apoptosis and Autophagy by Lorrie A. Kirshenbaum Pdf

One of the most intriguing and compelling issues to impact contemporary biology to date is the concept that cell death is genetically regulated. Observations by Kerr and Wyllie, made more than 30 years ago on the basis of distinct morphological criteria, markedly distinguished apoptosis from classical cell death by necrosis. Apoptosis is a highly regulated, evolutionary conserved, genetic program of cell death essential for normal development and tissue homeostasis. The discovery of apoptosis as a regulated event and potentially amenable to therapeutic interventions has generated considerable excitement because it meant that disease entities resulting from either too much, or too little, apoptosis could be potentially cured with new therapies that target apoptosis. While there is little doubt that necrosis induced by massive cellular trauma is likely an unregulated event, several lines of investigation have challenged the dogma that necrotic cell death is merely unregulated. Emerging data has shifted the paradigm in our thinking about necrosis as a regulated event. Autophagy is another cellular process that has received considerable attention over the past two decades and its remarkable involvement in the processes of cell survival, death and tumorigenesis. Macro autophagy is a catabolic process that involves the selective and targeted removal of oxidized proteins, macromolecular structures and organelles through an elaborate cellular process involving a lysosome mediated pathway. Other forms of autophagy involving adapter proteins, commonly referred to as chaperone mediated autophagy, involves the selective removal of cellular cargo by the ubiquitin-proteasome pathway. The book will serve as a reference guide for basic and clinical scientists who are interested in understanding how these critical cellular processes impact the pathogenesis of human disease.

Epigenetics in Health and Disease part B

Anonim
Epigenetics in Health and Disease part B Book PDF

Author : Anonim
Publisher : Elsevier
Page : 294 pages
File Size : 46,5 Mb
Release : 2023-05-23
Category : Science
ISBN : 9780443214455

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Epigenetics in Health and Disease part B by Anonim Pdf

Epigenetics in Health and Disease, Volume 198 in the Progress in Molecular Biology and Translational Science series, highlights new advances in the field, with this new volume presenting interesting chapters on Computational biology in epigenetics, Artificial intelligence and machine learning in epigenetics, CRISPR-dCas9 Systems for Epigenetic Editing for Therapeutic Applications, Epigenetics in heredity disease, Epigenetics in cancer development, diagnosis and therapy, Microbiota and epigenetics: health impact, Histone deacetylase (HDACs) Inhibitors: Clinical applications, Early epigenetic markers for precision medicine, Epigenetics of neurological diseases, Epigenetic Regulons in Alzheimer’s disease, and Epigenetics in epilepsy. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Progress in Molecular Biology and Translational Science series Includes the latest information on Epigenetics in Health and Disease

Janeway's Immunobiology

Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Janeway s Immunobiology Book PDF

Author : Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publisher : Garland Science
Page : 128 pages
File Size : 41,9 Mb
Release : 2010-06-22
Category : Medical
ISBN : 0815344570

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Janeway's Immunobiology by Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter Pdf

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Human Microbiome in Health and Disease - Part B

Anonim
Human Microbiome in Health and Disease Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 356 pages
File Size : 46,6 Mb
Release : 2022-10-22
Category : Science
ISBN : 9780323913218

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Human Microbiome in Health and Disease - Part B by Anonim Pdf

Human Microbiome in Health and Disease, Volume 192, Part B includes chapters surrounding the role of human microbiome in different diseases. Chapters in this comprehensive new volume include The microbiome and communicable diseases, Gut Microbiome and Antimicrobial Resistance in bacterial pathogens, Dysbiosis of human microbiome and infectious disease, Gastrointestinal microbiome in the context of infection in stomach and gastroduodenal diseases, Respiratory tract microbiome and pneumonia, Gut microbiome and neonatal sepsis, Diarrheal disease and gut microbiome, The microbiome and non-communicable diseases, Gut microbiome and inflammatory bowel disease, Gut microbiome and undernutrition, Human microbiome and cardiovascular disease, and much more. Covers dysbiosis of microbiome in communicable and non-communicable diseases Discusses the emergence and spread of antimicrobial resistance in gut microbiome Presents the latest information on reproductive tract microbiome and birth outcomes

Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B

Anonim
Dancing Protein Clouds Intrinsically Disordered Proteins in Health and Disease Part B Book PDF

Author : Anonim
Publisher : Academic Press
Page : 402 pages
File Size : 49,8 Mb
Release : 2020-08-19
Category : Science
ISBN : 9780128226049

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Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B by Anonim Pdf

Dancing Protein Clouds: Intrinsically Disordered Proteins in Health and Disease, Part B, represents a set of selected studies on a variety of research topics related to intrinsically disordered proteins. Topics in this update include structural and functional characterization of several important intrinsically disordered proteins, such as 14-3-3 proteins and their partners, as well as proteins from muscle sarcomere; representation of intrinsic disorder-related concept of protein structure-function continuum; discussion of the role of intrinsic disorder in phenotypic switching; consideration of the role of intrinsically disordered proteins in the pathogenesis of neurodegenerative diseases and cancer; discussion of the roles of intrinsic disorder in functional amyloids; demonstration of the usefulness of the analysis of translational diffusion of unfolded and intrinsically disordered proteins; consideration of various computational tools for evaluation of functions of intrinsically disordered regions; and discussion of the role of shear stress in the amyloid formation of intrinsically disordered regions in the brain. Provides some recent studies on the intrinsically disordered proteins and their functions, as well as on the involvement of intrinsically disordered proteins in pthogenesis of various diseases Contains numerous illustrative materials (color figures, diagrams, and tables) to help the readers to delve in the information provided Includes contributions from recognized experts in the field

Apoptosis

Douglas R. Green
Apoptosis Book PDF

Author : Douglas R. Green
Publisher : Cambridge University Press
Page : 470 pages
File Size : 45,7 Mb
Release : 2011-08-22
Category : Science
ISBN : 9781139498739

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Apoptosis by Douglas R. Green Pdf

Apoptosis, or cell death, can be pathological, a sign of disease and damage, or physiological, a process essential for normal health. This book, with contributions from experts in the field, provides a timely compilation of reviews of mechanisms of apoptosis. The book is organized into three convenient sections. The first section explores the different processes of cell death and how they relate to one another. The second section focuses on organ-specific apoptosis-related diseases. The third section explores cell death in non-mammalian organisms, such as plants. This comprehensive text is a must-read for all researchers and scholars interested in apoptosis.

Bioactive Ceramides in Health and Disease

Johnny Stiban
Bioactive Ceramides in Health and Disease Book PDF

Author : Johnny Stiban
Publisher : Springer Nature
Page : 153 pages
File Size : 46,6 Mb
Release : 2019-09-09
Category : Science
ISBN : 9783030211622

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Bioactive Ceramides in Health and Disease by Johnny Stiban Pdf

This book is about the various roles of bioactive ceramides and other sphingolipids in cellular biology. The enigmatic biophysical and biochemical properties of ceramides and their propensity to influence membranes whether as rafts or protein-permeable channels are heavily discussed. Metabolism of ceramides and their metabolites is also focused with ceramide synthase family of proteins being a target of extensive review. Ceramide 1-phosphate and other sphingolipids are also presented in cellular physiology and pathophysiology. Prokaryotic origins of mitochondria at the level of membranes and the occurrence of apoptosis in bacteria are presented. Many aspects of ceramide and sphingolipid biology are addressed in this book. Its focus is the metabolism of ceramide in normal and diseased states and the biophysical and biochemical mechanisms governing the bioactivity of these molecules. Sphingolipid research has surged over the past thirty years and this book gathers the recent findings of various aspects of sphingolipid biochemistry. World-renowned scientists from the field of lipid biology, specifically sphingolipid biochemistry, were gathered to write this book. Scholars from most continents of the globe committed to write diligently about their expertise and the newest findings in the relevant fields. This book came to fruition after almost a year and a half of laborious preparation and diligent writings. This book is targeted to the experienced reader who is looking to read about the various aspects of bioactive ceramide signaling, as well as to the newcomer into the field, as the topics are explained in concise yet very informative manner. The authors and editor wish all readers a pleasant time reading this volume, and are adamant that this book will meet all expectations.

How Tobacco Smoke Causes Disease

Anonim
How Tobacco Smoke Causes Disease Book PDF

Author : Anonim
Publisher : Unknown
Page : 728 pages
File Size : 51,7 Mb
Release : 2010
Category : Government publications
ISBN : UCSD:31822037817723

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How Tobacco Smoke Causes Disease by Anonim Pdf

This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.