Applications Of Mass Spectrometry In Life Safety

Author : Crisan Popescu,Alina D. Zamfir,Nicolae Dinca
Publisher : Springer Science & Business Media
Page : 238 pages
File Size : 44,9 Mb
Release : 2008-09-02
Category : Science
ISBN : 9781402088117

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Applications of Mass Spectrometry in Life Safety by Crisan Popescu,Alina D. Zamfir,Nicolae Dinca Pdf

Mass spectrometry (MS) along with its hyphenated techniques is capable of high throughput, sensitivity, accuracy and selectivity for the analysis of structure and composition of almost any product. Like in electrophoresis, MS separates mo- cules based on the mass-to-charge ratio. In case of gel electrophoresis (SDS- PAGE), a well-known and efficient bioanalytical technique, proteins bear negative charges but have the same charge density, so proteins are separated according to their size. Similarly, in case of MS analysis, proteins carry the same charge, and are separated by their molecular weight. Unlike SDS-PAGE, however, modern ultra high resolution MS discerns very small mass differences and can resolve and completely identify in a single experiment species of the same nominal mass in complex biological mixtures. Consequently, MS can be used for the structural characterization, identification and sensitive detection of mixtures of biomolecules or for assessing the quality of isolated proteins (purity, integrity, or post-translational modifications, for example), carbohydrates, nucleic acids, drugs, metabolites, pollutants etc. In the post-genome era, MS is continuously developing as one of the most re- able analytical method for elucidating the structure of molecules originating from various biological matrices. The potential of MS for high-sensitive structural a- lyses became unsurpassable after the introduction of electrospray (ESI) and matrix assisted laser/desorption ionization (MALDI) methods, on one hand, and the pos- bility to deduce in detail unknown biopolymer structures by highly accurate mo- cular mass measurement followed by sequencing using dissociation techniques based on multiple stage MS, on the other.

Author : Alisa G. Woods,Costel C. Darie
Publisher : Springer
Page : 601 pages
File Size : 54,9 Mb
Release : 2014-06-20
Category : Science
ISBN : 9783319060682

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Advancements of Mass Spectrometry in Biomedical Research by Alisa G. Woods,Costel C. Darie Pdf

This volume explores the use of mass spectrometry for biomedical applications. Chapters focus on specific therapeutic areas such as oncology, infectious disease and psychiatry. Additional chapters focus on methodology as well as new technologies and instrumentation. This volume provides readers with a comprehensive and informative manual that will allow them to appreciate mass spectrometry and proteomic research but also to initiate and improve their own work. Thus the book acts as a technical guide but also a conceptual guide to the newest information in this exciting field. Mass spectrometry is the central tool used in proteomic research today and is rapidly becoming indispensable to the biomedical scientist. With the completion of the human genome project and the genomic revolution, the proteomic revolution has followed closely behind. Understanding the human proteome has become critical to basic and clinical biomedical research and holds the promise of providing comprehensive understanding of human physiological processes. In addition, proteomics and mass spectrometry are bringing unprecedented biomarker discovery and are helping to personalize medicine.

Author : Evgeny Katz,Jan Halámek
Publisher : John Wiley & Sons
Page : 446 pages
File Size : 45,5 Mb
Release : 2016-03-08
Category : Medical
ISBN : 9783527693528

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Forensic Science by Evgeny Katz,Jan Halámek Pdf

Concentrating on the natural science aspects of forensics, top international authors from renowned universities, institutes, and laboratories impart the latest information from the field. In doing so they provide the background needed to understand the state of the art in forensic science with a focus on biological, chemical, biochemical, and physical methods. The broad subject coverage includes spectroscopic analysis techniques in various wavelength regimes, gas chromatography, mass spectrometry, electrochemical detection approaches, and imaging techniques, as well as advanced biochemical, DNA-based identification methods. The result is a unique collection of hard-to-get data that is otherwise only found scattered throughout the literature.

Author : Paul Garside,Emma Richardson
Publisher : Royal Society of Chemistry
Page : 503 pages
File Size : 41,6 Mb
Release : 2021-12-03
Category : Art
ISBN : 9781788010931

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Conservation Science 2E by Paul Garside,Emma Richardson Pdf

With contributions by scientists working in the museum and heritage sector, this textbook provides an overview of the analytical techniques and data processing methods used in modern conservation science. Each chapter deals with one of the common types of conservation materials in turn and provides case study examples of the techniques employed. It will interest students, scientists involved in conservation, and conservators who want to develop their understanding of their collections at a material level.

Author : Seiko Jose,Sabu Thomas,Pintu Pandit,Ritu Pandey
Publisher : John Wiley & Sons
Page : 420 pages
File Size : 44,8 Mb
Release : 2023-01-12
Category : Technology & Engineering
ISBN : 9781119983385

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Handbook of Museum Textiles, Volume 2 by Seiko Jose,Sabu Thomas,Pintu Pandit,Ritu Pandey Pdf

Handbook of Museum Textiles Textiles have been known to us throughout human history and played a vital role in the lives and traditions of people. Clothing was made by using different materials and methods from natural fibers. There are different varieties of textiles, out of which certain traditional textiles, archaeological findings, or fragments are of cultural, historical, and sentimental value such as tapestries, embroideries, flags, shawls, etc. These kinds of textiles, due to their historical use and environmental factors, require special attention to guarantee their long-term stability. Textile conservation is a complex, challenging, and multi-faceted discipline and it is one of the most versatile branches of conservation. Volume II of the Handbook of Museum Textiles provides precise instruction for conservation techniques to preserve the textile heritage more scientifically and technologically. Additionally, the book covers the most modern techniques used to characterize archaeological textiles and dyes. Progress and innovation in nanotechnology-based interventions in museum textiles are emphasized. Chapters cover the general introduction to biological damage caused by physical and chemical agents and their prevention methods. Information on microscopy and characterization of historical textiles, ancient dyes, and prints is highlighted. Several aspects of assessment of degradation, repair, and stabilization of antique textiles are presented in depth. Experimental research methods for diagnosis and scientific study of fibers and natural dyes using LC-MS and UV-VIS are described. Practical knowledge based on analysis and visualization of historical textiles for the needs of museum conservation, exhibition, digital technology, and virtual museums is addressed as well. Audience It will serve as an educational asset and tool for researchers, art scholars, archaeologists, museum curators, and those who are interested in the field of traditional or historic textile collections.

Author : Karoly Vekey,Andreas Telekes,Akos Vertes
Publisher : Elsevier
Page : 606 pages
File Size : 49,5 Mb
Release : 2011-08-11
Category : Science
ISBN : 9780080554655

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Medical Applications of Mass Spectrometry by Karoly Vekey,Andreas Telekes,Akos Vertes Pdf

Mass spectrometry is fast becoming an indispensable field for medical professionals. The mass spectrometric analysis of metabolites and proteins promises to revolutionize medical research and clinical diagnostics. As this technology rapidly enters the medical field, practicing professionals and students need to prepare to take full advantage of its capabilities. Medical Applications of Mass Spectrometry addresses the key issues in the medical applications of mass spectrometry at the level appropriate for the intended readership. It will go a long way to help the utilization of mass spectrometry in medicine. The book comprises five parts. A general overview is followed by a description of the basic sampling and separation methods in analytical chemistry. In the second part a solid foundation in mass spectrometry and modern techniques of data analysis is presented. The third part explains how mass spectrometry is used in exploring various classes of biomolecules, including proteins and lipids. In the fourth section mass spectrometry is introduced as a diagnostic tool in clinical treatment, infectious pathogen research, neonatal diagnostics, cancer, brain and allergy research, as well as in various fields of medicine: cardiology, pulmonology, neurology, psychiatric diseases, hemato-oncology, urologic diseases, gastrointestinal diseases, gynecology and pediatrics. The fifth part covers emerging applications in biomarker discovery and in mass spectrometric imaging. * Provides a broad look at how the medical field is benefiting from advances in mass spectrometry. * Guides the reader from basic principles and methods to cutting edge applications. * There is NO comparable book on the market to fill this fast growing field.

Author : Kurt F. J. Heinrich,Dale E. Newbury
Publisher : Unknown
Page : 244 pages
File Size : 45,6 Mb
Release : 1975
Category : Mass spectrometry
ISBN : UIUC:30112101555115

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Secondary Ion Mass Spectrometry by Kurt F. J. Heinrich,Dale E. Newbury Pdf

Author : Edmond de Hoffmann,Vincent Stroobant
Publisher : Wiley
Page : 420 pages
File Size : 41,8 Mb
Release : 2001-10-10
Category : Science
ISBN : 0471485659

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Mass Spectrometry by Edmond de Hoffmann,Vincent Stroobant Pdf

Offers a complete overview of the principles, theories and key applications of modern mass spectrometry in this introductory textbook. Following on from the highly successful first edition, this edition is extensively updated including new techniques and applications. All instrumental aspects of mass spectrometry are clearly and concisely described; sources, analysers and detectors. * Revised and updated * Numerous examples and illustrations are combined with a series of exercises to help encourage student understanding * Includes biological applications, which have been significantly expanded and updated * Also includes coverage of ESI and MALDI

Author : Leo M. L. Nollet
Publisher : John Wiley & Sons
Page : 506 pages
File Size : 48,8 Mb
Release : 2011-06-09
Category : Technology & Engineering
ISBN : 9780470961841

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Analysis of Endocrine Disrupting Compounds in Food by Leo M. L. Nollet Pdf

Analysis of Endocrine Disrupting Compounds in Food provides a unique and comprehensive professional reference source covering most of the recent analytical methodology of endocrine disrupting compounds in food. Editor Nollet and his broad team of international contributors address the most recent advances in analysis of endocrine disrupting chemicals in food. While covering conventional (typically lab-based) methods of analysis, the book focuses on leading-edge technologies that recently have been introduced. The book looks at areas such as food quality assurance and safety. Issues such as persistent organic pollutants, monitoring pesticide and herbicide residues in food, determining heavy and other metals in food and discussing the impacts of dioxins, PCBs, PCDFs and many other suspected chemicals are covered. The book discusses the relationship between chemical compounds and hormone activity. What are the health impacts of different chemical compounds for men and animals? How are these compounds entering in foodstuffs? Analysis of Endocrine Disrupting Compounds in Food offers the food professional what its title promises – a compendium of sample preparation and analysis techniques of possible endocrine disrupting compounds in food. Special Features: Uniquely concentrates on analysis and detection methods of EDCs in foodstuffs Extensive coverage of the main types of globally available analytical techniques and methodologies Fully detailed properties, sample procedures, and analysis steps for each EDC Renowned editor Leo Nollet leads a broad team of international experts

Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Page : 360 pages
File Size : 42,9 Mb
Release : 2017-03-07
Category : Science
ISBN : 9780128096482

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Applications in High Resolution Mass Spectrometry by Roberto Romero-González,Antonia Garrido Frenich Pdf

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Author : United States. Environmental Protection Agency. Library Systems Branch
Publisher : Unknown
Page : 702 pages
File Size : 44,9 Mb
Release : 1974
Category : Environmental protection
ISBN : UCR:31210012859458

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U.S. Environmental Protection Agency Library System Book Catalog Holdings as of July 1973 by United States. Environmental Protection Agency. Library Systems Branch Pdf

Author : Anonim
Publisher : Unknown
Page : 684 pages
File Size : 55,7 Mb
Release : 1968
Category : Weights and measures
ISBN : STANFORD:36105130366169

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NBS Special Publication by Anonim Pdf

Author : United States. National Bureau of Standards
Publisher : Unknown
Page : 668 pages
File Size : 46,7 Mb
Release : 1980
Category : Government publications
ISBN : UOM:39015079557404

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Publications by United States. National Bureau of Standards Pdf

Author : United States. National Bureau of Standards
Publisher : Unknown
Page : 686 pages
File Size : 41,7 Mb
Release : 1980
Category : Electronic
ISBN : UCAL:$B751381

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Publications of the National Bureau of Standards ... Catalog by United States. National Bureau of Standards Pdf

Author : National Institute of Standards and Technology (U.S.)
Publisher : Unknown
Page : 680 pages
File Size : 42,9 Mb
Release : 1981
Category : Electronic
ISBN : UIUC:30112101564877

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Publications of the National Institute of Standards and Technology ... Catalog by National Institute of Standards and Technology (U.S.) Pdf