Applications Of Time Of Flight And Orbitrap Mass Spectrometry In Environmental Food Doping And Forensic Analysis

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Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis

Author : Anonim
Publisher : Elsevier
Page : 524 pages
File Size : 50,7 Mb
Release : 2016-06-02
Category : Science
ISBN : 9780444635730

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Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis by Anonim Pdf

Applications of Time-of-Flight and Orbitrap Mass Spectrometry in Environmental, Food, Doping, and Forensic Analysis deals with the use of high-resolution mass spectrometry (MS) in the analysis of small organic molecules. Over the past few years, time-of-flight (ToF) and Orbitrap MS have both experienced tremendous growth in a great number of analytical sectors and are now well established in many laboratories where high requirements are placed on analytical performance. This book gives a head-to-head comparison of these two technologies that compete directly with each other. As users with hands-on experience in both techniques, the authors provide a balanced description of the strengths and weaknesses of both techniques. In the vast majority of cases, ToF-MS and Orbitrap-MS have been used for qualitative purposes, mainly identification of discrete molecular entities such as drug metabolites or transformation products of environmental contaminants. This paradigm is now changing as quantitative capabilities are increasingly being explored, as are non-target approaches for unbiased broad-scope screening. In view of the continuous innovation of high-resolution MS instrument manufacturers in designing and developing more powerful machines, technological advances in both hardware and software are considerable, with many novel applications. This book summarizes and analyzes these trends. The compilation of selected examples from diverse analytical fields will allow the readers to discover not only the potential of high-resolution MS in their sector, but also shows advances in other fields that rely on hi-res MS. Provides comprehensive coverage of applications of time-of-flight and orbitrap mass spectrometry in environmental, food, doping, and forensic analysis Explores a variety of specialized techniques, giving a balanced description of the strengths and weaknesses of each Presents a general overview of imaging techniques within analysis

Determination of Target Xenobiotics and Unknown Compound Residues in Food, Environmental, and Biological Samples

Author : Tomasz Tuzimski,Joseph Sherma
Publisher : CRC Press
Page : 607 pages
File Size : 46,7 Mb
Release : 2018-10-25
Category : Science
ISBN : 9780429823091

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Determination of Target Xenobiotics and Unknown Compound Residues in Food, Environmental, and Biological Samples by Tomasz Tuzimski,Joseph Sherma Pdf

Xenobiotics are chemical compounds foreign to a given biological system. In animals and humans, xenobiotics include drugs, drug metabolites, and environmental pollutants. In the environment, xenobiotics include synthetic pesticides, herbicides, and industrial pollutants. Many techniques are used in xenobiotics residue analysis; the method selected depends on the complexity of the sample, the nature of the matrix/analytes, and the analytical techniques available. This reference will help the analyst develop effective and validated analytical strategies for the analysis of hundreds of different xenobiotics on hundreds of different sample types, quickly, accurately and at acceptable cost.

Applications in High Resolution Mass Spectrometry

Author : Roberto Romero-González,Antonia Garrido Frenich
Publisher : Elsevier
Page : 360 pages
File Size : 42,5 Mb
Release : 2017-03-07
Category : Science
ISBN : 9780128096482

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Applications in High Resolution Mass Spectrometry by Roberto Romero-González,Antonia Garrido Frenich Pdf

Applications of High Resolution Mass Spectrometry: Food Safety and Pesticide Residue Analysis is the first book to offer complete coverage of all aspects of high resolution mass spectrometry (HRMS) used for the analysis of pesticide residue in food. Aimed at researchers and graduate students in food safety, toxicology, and analytical chemistry, the book equips readers with foundational knowledge of HRMS, including established and state-of-the-art principles and analysis strategies. Additionally, it provides a roadmap for implementation, including discussions of the latest instrumentation and software available. Detailed coverage is given to the application of HRMS coupled to ultra high-performance liquid chromatography (UHPLC-HRMS) in the analysis of pesticide residue in fruits and vegetables and food from animal origin. The book also discusses extraction procedures and the challenges of sample preparation, gas chromatography coupled to high resolution mass spectrometry, flow injection-HRMS, ambient ionization, and identification of pesticide transformation products in food. Responding to the fast development and application of these new procedures, this book is an essential resource in the food safety field. Arms researchers with an in-depth resource devoted to the rapid advances in HRMS tools and strategies for pesticide residue analysis in food Provides a complete overview of analytical methodologies and applications of HRMS, including UHPLC-HRMS, HRMS coupled with time of flight (TOF) and/or GC-Orbitrap, and flow injection-HRMS Discusses the current international regulations and legislation related to the use of HRMS in pesticide residue analysis Features a chapter on the hardware and software available for HRMS implementation Offers separate chapters on HRMS applied to pesticide residue analysis in fruits and vegetables and in food from animal origin

Ambient Mass Spectroscopy Techniques in Food and the Environment

Author : Leo M.L. Nollet,Basil K. Munjanja
Publisher : CRC Press
Page : 228 pages
File Size : 40,7 Mb
Release : 2019-01-30
Category : Health & Fitness
ISBN : 9781351378499

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Ambient Mass Spectroscopy Techniques in Food and the Environment by Leo M.L. Nollet,Basil K. Munjanja Pdf

Ambient mass spectrometry—that is the use of mass spec but in the atmospheric environment—has been widely employed in food and environmental analysis. Ambient Mass Spectroscopy Techniques in Food and the Environment presents the theoretical underpinnings of mass spectrometry, and the benefits and pitfalls of ambient mass spectrometry, as well as the latest developments of the technique, in the analysis of food and environmental parameters. It describes methods that enable the detection of surface materials like waxes, alkaloids, flavors, or pesticides by plainly exposing the corresponding items to the ionization region of the interface, without harm to samples. Features: Explains the theoretical aspects of ambient mass spectrometry Describes how to use ambient MS techniques for food safety, authenticity, and traceability screening Lists the benefits of ambient MS in analysis of food and environmental parameters Covers recent developments of ambient MS in analysis of food and environmental parameters The specialized work provides insight to professionals practicing in food and the environment, including food scientists, food engineers, food biotechnologists, chemical engineers, and those working in research labs, universities, and government regulatory agencies.

Food Toxicology and Forensics

Author : Charis M. Galanakis
Publisher : Academic Press
Page : 495 pages
File Size : 54,5 Mb
Release : 2020-11-11
Category : Medical
ISBN : 9780128223611

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Food Toxicology and Forensics by Charis M. Galanakis Pdf

Food Toxicology and Forensics presents an overview on these subjects, along with the analytical tools necessary to handle the complexity of the issues at play between them. The book discusses the presence of foreign substances in food despite forensic analysis and supports the scientific community, laboratories and regulatory bodies in their aim to identify food fraud. Topics include the forensic attribution profiling of food by liquid chromatography (LC), contemporary mass spectrometry (MS), tandem mass spectrometry (MS/MS) and liquid chromatography coupled to mass spectrometry (LC-MS), the application of ambient ionization mass spectrometry (AIMS) techniques for the analysis of food samples, and more. Includes toxicology and analytical methods for the determination of certain toxicants in foods Discusses legal, economic and biological issues of food adulteration and food fraud Presents the latest allergen measurement techniques and post reviews of allergen non-compliance cases Provides methods of validation of DNA biochip for species identification in food forensic science

Mass Spectrometry Imaging in Food Analysis

Author : Leo M.L. Nollet
Publisher : CRC Press
Page : 215 pages
File Size : 50,8 Mb
Release : 2020-04-29
Category : Science
ISBN : 9780429765308

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Mass Spectrometry Imaging in Food Analysis by Leo M.L. Nollet Pdf

Food contains various compounds and many technologies exist to analyze those molecules of interest. However, the analysis of the spatial distribution of those compounds using conventional technology, such as liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Mass spectrometry imaging (MSI) is a mass spectrometry technique to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte and so quantification is possible. Mass Spectrometry Imaging in Food Analysis, a volume in the Food Analysis and Properties Series, explains how the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) will be an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. It can be used to visualize the spatial distribution of biomolecules in foods. Features: Explains the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging in food analysis Describes how MALDI-MSI will be a useful technique for optical quality assurance. Shows how MALDI-MSI detects food contaminants and residues Covers the historical development of the technology While there are a multitude of books on mass spectrometry, none focus on food applications and thus this book is ideally suited to food scientists, food industry personnel engaged in product development, research institutions, and universities active in food analysis or chemical analysis. Also available in the Food Analysis and Properties Series: Food Aroma Evolution: During Food Processing, Cooking, and Aging, edited by Matteo Bordiga and Leo M.L. Nollet (ISBN: 9781138338241) Ambient Mass Spectroscopy Techniques in Food and the Environment, edited by Leo M.L. Nollet and Basil K. Munjanja (ISBN: 9781138505568) Hyperspectral Imaging Analysis and Applications for Food Quality, edited by N.C. Basantia, Leo M.L. Nollet, and Mohammed Kamruzzaman (ISBN: 9781138630796) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

High-Resolution Mass Spectroscopy for Phytochemical Analysis

Author : Sreeraj Gopi,Augustine Amalraj,Shintu Jude
Publisher : CRC Press
Page : 270 pages
File Size : 43,6 Mb
Release : 2021-09-30
Category : Science
ISBN : 9781000353419

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High-Resolution Mass Spectroscopy for Phytochemical Analysis by Sreeraj Gopi,Augustine Amalraj,Shintu Jude Pdf

This new volume provides a bird’s-eye view of the properties, utilization, and importance of high resolution mass spectrometry (HRMS) for phytochemical analysis. The book discusses the new and state-of-the-art technologies related to HRMS in phytochemical analysis for the food industry in a comprehensive manner. Phytochemical characterization of plants is important in the food and nutraceutical industries and is also necessary in the procedures followed for drug development, toxicology determination, forensic studies, origin verification, quality assurance, etc. Easy determination of active compounds and isolation as well as purification of the same from natural matrices are required, and the possibilities and advantages of HRMS pave the way for improved analysis patterns in phytochemistry. This book is unique in that its sole consideration is on the importance of HRMS in the field of phytochemical analysis. Along with an overview of basic instrumental information, the volume provides a detailed account of data processing and dereplication strategies. Technologies such as bioanalytical techniques and bioassays are considered also to provide support for the functions of the instruments used. In addition, a case study is presented to depict the complete phytochemical characterization of a matrix by HRMS. The book covers processing and computational techniques, dereplication, hyphenation, high-resolution bioassays, bioanalytical screening/purification techniques, applications of gas chromatography–high-resolution mass spectrometry, and more. Key features: Covers the fundamental instrumentation and techniques Discusses HRMS-based phytochemical research details Focuses strictly on the phytochemical considerations High-Resolution Mass Spectroscopy for Phytochemical Analysis: State-of-the-Art Applications and Techniques will be a valuable reference guide and resource for researchers, faculty and students in related fields, as well as those in the phytochemical industries.

Mass Spectrometry in Food Analysis

Author : Leo M. L. Nollet,Robert Winkler
Publisher : CRC Press
Page : 462 pages
File Size : 49,9 Mb
Release : 2022-03-21
Category : Technology & Engineering
ISBN : 9781000539257

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Mass Spectrometry in Food Analysis by Leo M. L. Nollet,Robert Winkler Pdf

The quality and safety of food are crucial for human nutrition. However, evaluating the chemical composition of food is challenging for the analyst and requires powerful methods. Chromatography and mass spectrometry (MS) is the gold standard for analyzing complex food samples, including raw materials and intermediate and finished products. Mass Spectrometry in Food Analysis covers the MS-based analysis of different aspects of food quality, which include nutritional value, profile of macronutrients (proteins, lipids, and carbohydrates), micronutrients (vitamins), and nutraceutical active compounds. Additionally, sensory quality, flavor, food pigments, safety, and detection of pesticides, contact materials, veterinary drugs and pharmaceuticals, organic pollutants, and pathogens are covered. Key Features: Contains the basics of mass spectrometry and experimental strategies Explores determination of macro- and micronutrients Analyzes sensory and nutraceutical food quality Discusses detection of contaminants and proof of authenticity Presents emerging methods for food analysis This book contains an introductory section that explains the basics of MS and the difference between targeted and untargeted strategies for beginners. Further, it points out new analytical challenges, such as monitoring contaminants of emerging concern, and presents innovative techniques (e.g., ambient ionization MS and data mining). Also available in the Food Analysis & Properties Series: Nanoemulsions in Food Technology: Development, Characterization, and Applications, edited by Javed Ahmad and Leo M.L. Nollet (ISBN: 978-0-367-61492-8) Sequencing Technologies in Microbial Food Safety and Quality, edited by Devarajan Thangadurai, Leo M.L. Nollet, Saher Islam, and Jeyabalan Sangeetha (ISBN: 978-0-367-35118-2) Chiral Organic Pollutants: Monitoring and Characterization in Food and the Environment, edited by Edmond Sanganyado, Basil K. Munjanja, and Leo M.L. Nollet (ISBN: 978-0-367-42923-2) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

Fundamentals and Applications of Fourier Transform Mass Spectrometry

Author : Philippe Schmitt-Kopplin,Basem Kanawati
Publisher : Elsevier
Page : 778 pages
File Size : 44,6 Mb
Release : 2019-08-11
Category : Science
ISBN : 9780128140147

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Fundamentals and Applications of Fourier Transform Mass Spectrometry by Philippe Schmitt-Kopplin,Basem Kanawati Pdf

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Forensic Analytical Methods

Author : Thiago R L C Paixão,Wendell K T Coltro,Maiara Oliveira Salles
Publisher : Royal Society of Chemistry
Page : 312 pages
File Size : 48,6 Mb
Release : 2019-08-16
Category : Science
ISBN : 9781788014595

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Forensic Analytical Methods by Thiago R L C Paixão,Wendell K T Coltro,Maiara Oliveira Salles Pdf

Forensic analysis relates to the development of analytical methods from laboratory applications to in-field and in situ applications to resolve criminal cases. There has been a rapid expansion in the past few years in this area, which has led to an increase in the output of literature. This is the first book that brings together the understanding of the analytical techniques and how these influence the outcome of a forensic investigation. Starting with a brief introduction of the chemical analysis for forensic application, some forensic sampling and sample preparation, the book then describes techniques used in forensic chemical sensing in order to solve crimes. The techniques describe current forensic science practices in analytical chemistry and specifically the development of portable detectors to guide the authorities in the field. The book provides an excellent combination of current issues in forensic analytical methods for the graduates and professionals. It will cover the essential principles for students and directly relate the techniques to applications in real situations.

TOF-MS Within Food and Environmental Analysis

Author : Amadeo Rodriguez Fernandez-Alba
Publisher : Elsevier
Page : 452 pages
File Size : 42,5 Mb
Release : 2012-09-06
Category : Science
ISBN : 9780444538109

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TOF-MS Within Food and Environmental Analysis by Amadeo Rodriguez Fernandez-Alba Pdf

New developments in mass spectrometry have allowed routine identification and lowered limits of detection at levels only imagined a decade ago. Thousands of contaminants and residues in the food supply and the environment are now being reported. Between 2005 and 2010, more than 5,000 publications covering TOF-MS and environmental and food analysis were published, showing the importance of the technique in these applications. This book covers the basic principles of method development in GC- and LC-TOF-MS as well as the main operational parameters related to TOF-MS. The second part focuses on the relevant environmental applications, including quality control aspects as well as data collection. The third part is devoted to relevant applications in food analysis, including validation procedures for screening analysis as well as relevant databases. Outlines basic concepts and principles of gas and liquid chromatography TOF-MS and its application in food analysis Includes quality control and data collection techniques Focuses on environmental implications and safety concerns

Fast Liquid Chromatography–Mass Spectrometry Methods in Food and Environmental Analysis

Author : Oscar Núñez,Héctor Gallart-Ayala,Claudia P B Martins,Paolo Lucci
Publisher : World Scientific
Page : 624 pages
File Size : 51,5 Mb
Release : 2015-02-13
Category : Science
ISBN : 9781783264957

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Fast Liquid Chromatography–Mass Spectrometry Methods in Food and Environmental Analysis by Oscar Núñez,Héctor Gallart-Ayala,Claudia P B Martins,Paolo Lucci Pdf

There is a growing need for high-throughput separations in food and environmental research that are able to cope with the analysis of a large number of compounds in very complex matrices. Whereas the most common approach for solving many analytical problems has often been high-performance liquid chromatography (HPLC), the recent use of fast or ultra-fast chromatographic methods for environmental and food analysis has increased the overall sample throughput and laboratory efficiency without loss (and even with an improvement) in the resolution obtained by conventional HPLC systems. This book brings together researchers at the top of their field from across the world to discuss and analyze recent advances in fast liquid chromatography–mass spectrometry (LC–MS) methods in food and environmental analysis. First, the most novel approaches to achieve fast and ultra-fast methods as well as the use of alternative and complementary stationary phases are described. Then, recent advances in fast LC–MS methods are addressed, focusing on novel treatment procedures coupled with LC–MS, new ionization sources, high-resolution mass spectrometry, and the problematic confirmation and quantification aspects in mass spectrometry. Finally, relevant LC–MS applications in food and environmental analysis such as the analysis of pesticides, mycotoxins, food packaging contaminants, perfluorinated compounds and polyphenolic compounds are described. The scope of the book is intentionally broad and is aimed at worldwide analytical laboratories working in food and environmental applications as well as researchers in universities worldwide. Contents: Fast Liquid Chromatography Advances:UHPLC Separations Using Sub-2 μm Particle Size Columns (Julie Schappler, Jean-Luc Veuthey and Davy Guillarme)Core-Shell Column Technology in Fast Liquid Chromatography (Oscar Núñez and Héctor Gallart-Ayala)Monolithic Columns in Fast Liquid Chromatography (Takeshi Hara, Oscar Núñez, Tohru Ikegami and Nobuo Tanaka)High-Temperature Liquid Chromatography (Thorsten Teutenberg)Hydrophilic Interaction Liquid Chromatography (HILIC) and Perfluorinated Stationary Phases (Cristina C Jacob, Héctor Gallart-Ayala and Gonçalo Gamboa da Costa)Advances in Fast Liquid Chromatography–Mass Spectrometry Methods:On-Line Sample Pre-Treatment Procedures Applied to LC–MS (Tony Edge and Joseph Herman)Ambient Mass Spectrometry: Food and Environmental Applications (Tiina J Kauppila and Anu Vaikkinen)Liquid Chromatography–High–Resolution Mass Spectrometry in Environmental and Food Analysis (Paolo Lucci and Claudia P B Martins)Liquid Chromatography–Mass Spectrometry: Quantification and Confirmation Aspects (Jaume Aceña, Daniel Rivas, Bozo Zonja, Sandra Pérez and Damià Barceló)Relevant LC–MS Applications in Food and Environmental Analysis:Multiresidue Analysis of Pesticides: LC–MS/MS versus LC–HRMS (Juan V Sancho and María Ibáñez)Food-Packaging Contaminants (Silvia Lacorte, Montse Cortina, Albert Guart and Antonio Borrell)Liquid Chromatography–Mass Spectrometry for the Analysis of Perfluorinated Compounds in Water Samples (Marianna Rusconi, Stefano Polesello and Sara Valsecchi)Determination of Phenolic Compounds in Food Matrices: Application to Characterization and Authentication (Javier Saurina and Sonia Sentellas)Liquid Chromatography–Mass Spectrometric Analysis of Mycotoxins in Food (Veronica M T Lattanzio and Angelo Visconti) Readership: Scientists or students in mass spectrometry, chemists, biologists, and analysts. Keywords:Mass Spectrometry;Fast Liquid Chromatography;Food Analysis;Environmental Analysis

Practical Gas Chromatography

Author : Katja Dettmer-Wilde,Werner Engewald
Publisher : Springer
Page : 904 pages
File Size : 46,7 Mb
Release : 2014-11-05
Category : Science
ISBN : 9783642546402

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Practical Gas Chromatography by Katja Dettmer-Wilde,Werner Engewald Pdf

Gas chromatography continues to be one of the most widely used analytical techniques, since its applications today expand into fields such as biomarker research or metabolomics. This new practical textbook enables the reader to make full use of gas chromatography. Essential fundamentals and their implications for the practical work at the instrument are provided, as well as details on the instrumentation such as inlet systems, columns and detectors. Specialized techniques from all aspects of GC are introduced ranging from sample preparation, solvent-free injection techniques, and pyrolysis GC, to separation including fast GC and comprehensive GCxGC and finally detection, such as GC-MS and element-specific detection. Various fields of application such as enantiomer, food, flavor and fragrance analysis, physicochemical measurements, forensic toxicology, and clinical analysis are discussed as well as cutting-edge application in metabolomics is covered.

Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food

Author : Jack F. Kay,James D. MacNeil,Jian Wang
Publisher : John Wiley & Sons
Page : 640 pages
File Size : 49,5 Mb
Release : 2016-11-21
Category : Science
ISBN : 9781119325901

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Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food by Jack F. Kay,James D. MacNeil,Jian Wang Pdf

Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and potential applications for non-antimicrobial veterinary drugs Provides guidance for analysis of banned drugs including natural and synthetic steroids, Resorcylic acid lactones, and Beta-agonists

Liquid Chromatography Time-of-Flight Mass Spectrometry

Author : Imma Ferrer,E. Michael Thurman
Publisher : John Wiley & Sons
Page : 281 pages
File Size : 53,7 Mb
Release : 2009-05-06
Category : Science
ISBN : 9780470429952

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Liquid Chromatography Time-of-Flight Mass Spectrometry by Imma Ferrer,E. Michael Thurman Pdf

Time of flight mass spectrometry identifies the elements of a compound by subjecting a sample of ions to a strong electrical field. Illuminating emerging analytical techniques in high-resolution mass spectrometry, Liquid Chromatography Time-of-Flight Mass Spectrometry shows readers how to analyze unknown and emerging contaminants—such as antibiotics, steroids, analgesics—using advanced mass spectrometry techniques. The text combines theoretical discussion with concrete examples, making it suitable for analytical chemists, environmental chemists, organic chemists, medicinal chemists, university research chemists, and graduate and post-doctorate students.