Applied Adaptive Statistical Methods

Author : Thomas W. O'Gorman
Publisher : SIAM
Page : 187 pages
File Size : 52,7 Mb
Release : 2004-01-01
Category : Mathematics
ISBN : 0898718430

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Applied Adaptive Statistical Methods by Thomas W. O'Gorman Pdf

Adaptive statistical tests, developed over the last 30 years, are often more powerful than traditional tests of significance, but have not been widely used. To date, discussions of adaptive statistical methods have been scattered across the literature and generally do not include the computer programs necessary to make these adaptive methods a practical alternative to traditional statistical methods. Until recently, there has also not been a general approach to tests of significance and confidence intervals that could easily be applied in practice. Modern adaptive methods are more general than earlier methods and sufficient software has been developed to make adaptive tests easy to use for many real-world problems. Applied Adaptive Statistical Methods: Tests of Significance and Confidence Intervals introduces many of the practical adaptive statistical methods developed over the last 10 years and provides a comprehensive approach to tests of significance and confidence intervals. It shows how to make confidence intervals shorter and how to make tests of significance more powerful by using the data itself to select the most appropriate procedure.

Author : John Van Ryzin
Publisher : Unknown
Page : 476 pages
File Size : 53,6 Mb
Release : 2008*
Category : Bayesian statistical decision theory
ISBN : OCLC:275471696

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Adaptive Statistical Procedures and Related Topics by John Van Ryzin Pdf

This e-book is the product of Project Euclid and its mission to advance scholarly communication in the field of theoretical and applied mathematics and statistics. Project Euclid was developed and deployed by the Cornell University Library and is jointly managed by Cornell and the Duke University Press.

Author : John Van Ryzin
Publisher : IMS
Page : 496 pages
File Size : 52,9 Mb
Release : 1986
Category : Mathematics
ISBN : 0940600099

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Adaptive Statistical Procedures and Related Topics by John Van Ryzin Pdf

Author : Thomas W. O'Gorman
Publisher : John Wiley & Sons
Page : 364 pages
File Size : 47,7 Mb
Release : 2012-03-13
Category : Mathematics
ISBN : 9781118218228

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Adaptive Tests of Significance Using Permutations of Residuals with R and SAS by Thomas W. O'Gorman Pdf

Provides the tools needed to successfully perform adaptive testsacross a broad range of datasets Adaptive Tests of Significance Using Permutations of Residualswith R and SAS illustrates the power of adaptive tests andshowcases their ability to adjust the testing method to suit aparticular set of data. The book utilizes state-of-the-art softwareto demonstrate the practicality and benefits for data analysis invarious fields of study. Beginning with an introduction, the book moves on to explore theunderlying concepts of adaptive tests, including: Smoothing methods and normalizing transformations Permutation tests with linear methods Applications of adaptive tests Multicenter and cross-over trials Analysis of repeated measures data Adaptive confidence intervals and estimates Throughout the book, numerous figures illustrate the keydifferences among traditional tests, nonparametric tests, andadaptive tests. R and SAS software packages are used to perform thediscussed techniques, and the accompanying datasets are availableon the book's related website. In addition, exercises at the end ofmost chapters enable readers to analyze the presented datasets byputting new concepts into practice. Adaptive Tests of Significance Using Permutations of Residualswith R and SAS is an insightful reference for professionals andresearchers working with statistical methods across a variety offields including the biosciences, pharmacology, and business. Thebook also serves as a valuable supplement for courses on regressionanalysis and adaptive analysis at the upper-undergraduate andgraduate levels.

Author : Michael R. Kosorok,Erica E. M. Moodie
Publisher : SIAM
Page : 354 pages
File Size : 48,6 Mb
Release : 2015-12-08
Category : Medical
ISBN : 9781611974171

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Adaptive TreatmentStrategies in Practice: Planning Trials and Analyzing Data for Personalized Medicine by Michael R. Kosorok,Erica E. M. Moodie Pdf

Personalized medicine is a medical paradigm that emphasizes systematic use of individual patient information to optimize that patient's health care, particularly in managing chronic conditions and treating cancer. In the statistical literature, sequential decision making is known as an adaptive treatment strategy (ATS) or a dynamic treatment regime (DTR). The field of DTRs emerges at the interface of statistics, machine learning, and biomedical science to provide a data-driven framework for precision medicine.? The authors provide a learning-by-seeing approach to the development of ATSs, aimed at a broad audience of health researchers. All estimation procedures used are described in sufficient heuristic and technical detail so that less quantitative readers can understand the broad principles underlying the approaches. At the same time, more quantitative readers can implement these practices. This book provides the most up-to-date summary of the current state of the statistical research in personalized medicine; contains chapters by leaders in the area from both the statistics and computer sciences fields; and also contains a range of practical advice, introductory and expository materials, and case studies.?

Author : Thomas W. O'Gorman
Publisher : John Wiley & Sons
Page : 365 pages
File Size : 47,7 Mb
Release : 2012-03-13
Category : Mathematics
ISBN : 9780470922255

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Adaptive Tests of Significance Using Permutations of Residuals with R and SAS by Thomas W. O'Gorman Pdf

Provides the tools needed to successfully perform adaptive tests across a broad range of datasets Adaptive Tests of Significance Using Permutations of Residuals with R and SAS illustrates the power of adaptive tests and showcases their ability to adjust the testing method to suit a particular set of data. The book utilizes state-of-the-art software to demonstrate the practicality and benefits for data analysis in various fields of study. Beginning with an introduction, the book moves on to explore the underlying concepts of adaptive tests, including: Smoothing methods and normalizing transformations Permutation tests with linear methods Applications of adaptive tests Multicenter and cross-over trials Analysis of repeated measures data Adaptive confidence intervals and estimates Throughout the book, numerous figures illustrate the key differences among traditional tests, nonparametric tests, and adaptive tests. R and SAS software packages are used to perform the discussed techniques, and the accompanying datasets are available on the book's related website. In addition, exercises at the end of most chapters enable readers to analyze the presented datasets by putting new concepts into practice. Adaptive Tests of Significance Using Permutations of Residuals with R and SAS is an insightful reference for professionals and researchers working with statistical methods across a variety of fields including the biosciences, pharmacology, and business. The book also serves as a valuable supplement for courses on regression analysis and adaptive analysis at the upper-undergraduate and graduate levels.

Author : Bernhard Schipp,Walter Krämer
Publisher : Springer Science & Business Media
Page : 438 pages
File Size : 51,5 Mb
Release : 2008-11-27
Category : Mathematics
ISBN : 9783790821215

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Statistical Inference, Econometric Analysis and Matrix Algebra by Bernhard Schipp,Walter Krämer Pdf

This Festschrift is dedicated to Götz Trenkler on the occasion of his 65th birthday. As can be seen from the long list of contributions, Götz has had and still has an enormous range of interests, and colleagues to share these interests with. He is a leading expert in linear models with a particular focus on matrix algebra in its relation to statistics. He has published in almost all major statistics and matrix theory journals. His research activities also include other areas (like nonparametrics, statistics and sports, combination of forecasts and magic squares, just to mention afew). Götz Trenkler was born in Dresden in 1943. After his school years in East G- many and West-Berlin, he obtained a Diploma in Mathematics from Free University of Berlin (1970), where he also discovered his interest in Mathematical Statistics. In 1973, he completed his Ph.D. with a thesis titled: On a distance-generating fu- tion of probability measures. He then moved on to the University of Hannover to become Lecturer and to write a habilitation-thesis (submitted 1979) on alternatives to the Ordinary Least Squares estimator in the Linear Regression Model, a topic that would become his predominant ?eld of research in the years to come.

Author : Karl E. Peace,Ding-Geng Chen,Sandeep Menon
Publisher : Springer
Page : 409 pages
File Size : 46,5 Mb
Release : 2018-08-20
Category : Medical
ISBN : 9789811078293

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Biopharmaceutical Applied Statistics Symposium by Karl E. Peace,Ding-Geng Chen,Sandeep Menon Pdf

This BASS book Series publishes selected high-quality papers reflecting recent advances in the design and biostatistical analysis of biopharmaceutical experiments – particularly biopharmaceutical clinical trials. The papers were selected from invited presentations at the Biopharmaceutical Applied Statistics Symposium (BASS), which was founded by the first Editor in 1994 and has since become the premier international conference in biopharmaceutical statistics. The primary aims of the BASS are: 1) to raise funding to support graduate students in biostatistics programs, and 2) to provide an opportunity for professionals engaged in pharmaceutical drug research and development to share insights into solving the problems they encounter.The BASS book series is initially divided into three volumes addressing: 1) Design of Clinical Trials; 2) Biostatistical Analysis of Clinical Trials; and 3) Pharmaceutical Applications. This book is the first of the 3-volume book series. The topics covered include: A Statistical Approach to Clinical Trial Simulations, Comparison of Statistical Analysis Methods Using Modeling and Simulation for Optimal Protocol Design, Adaptive Trial Design in Clinical Research, Best Practices and Recommendations for Trial Simulations in the Context of Designing Adaptive Clinical Trials, Designing and Analyzing Recurrent Event Data Trials, Bayesian Methodologies for Response-Adaptive Allocation, Addressing High Placebo Response in Neuroscience Clinical Trials, Phase I Cancer Clinical Trial Design: Single and Combination Agents, Sample Size and Power for the Mixed Linear Model, Crossover Designs in Clinical Trials, Data Monitoring: Structure for Clinical Trials and Sequential Monitoring Procedures, Design and Data Analysis for Multiregional Clinical Trials – Theory and Practice, Adaptive Group-Sequential Multi-regional Outcome Studies in Vaccines, Development and Validation of Patient-reported Outcomes, Interim Analysis of Survival Trials: Group Sequential Analyses, and Conditional Power – A Non-proportional Hazards Perspective.

Author : Irving W. Burr
Publisher : Academic Press
Page : 479 pages
File Size : 51,5 Mb
Release : 1973
Category : Electronic
ISBN : 0121461521

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Applied Statistical Methods by Irving W. Burr Pdf

Author : Shein-Chung Chow,Mark Chang
Publisher : CRC Press
Page : 368 pages
File Size : 40,6 Mb
Release : 2011-12-01
Category : Mathematics
ISBN : 9781439839881

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Adaptive Design Methods in Clinical Trials by Shein-Chung Chow,Mark Chang Pdf

With new statistical and scientific issues arising in adaptive clinical trial design, including the U.S. FDA's recent draft guidance, a new edition of one of the first books on the topic is needed. Adaptive Design Methods in Clinical Trials, Second Edition reflects recent developments and regulatory positions on the use of adaptive designs in clini

Author : Annpey Pong,Shein-Chung Chow
Publisher : CRC Press
Page : 496 pages
File Size : 43,7 Mb
Release : 2016-04-19
Category : Mathematics
ISBN : 1439810176

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Handbook of Adaptive Designs in Pharmaceutical and Clinical Development by Annpey Pong,Shein-Chung Chow Pdf

In response to the US FDA's Critical Path Initiative, innovative adaptive designs are being used more and more in clinical trials due to their flexibility and efficiency, especially during early phase development. Handbook of Adaptive Designs in Pharmaceutical and Clinical Development provides a comprehensive and unified presentation of the princip

Author : Peter R. Nelson,Peter S. Wludyka,Karen A. F. Copeland
Publisher : SIAM
Page : 259 pages
File Size : 53,5 Mb
Release : 2005-01-01
Category : Analysis of means
ISBN : 0898718368

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The Analysis of Means by Peter R. Nelson,Peter S. Wludyka,Karen A. F. Copeland Pdf

The analysis of means (ANOM) is a graphical procedure used to quantify differences among treatment groups in a variety of experimental design and observational study situations. The ANOM decision chart allows one to easily draw conclusions and interpret results with respect to both statistical and practical significance. It is an excellent choice for multiple comparisons of means, rates, or proportions and can be used with both balanced and unbalanced data. Key advances in ANOM procedures that have appeared only in technical journals during the last 20 years are included in this first comprehensive modern treatment of the ANOM containing all of the needed information for practitioners to understand and apply ANOM.

Author : Veronica Czitrom,Patrick D. Spagon
Publisher : SIAM
Page : 510 pages
File Size : 49,7 Mb
Release : 1997-01-01
Category : Technology & Engineering
ISBN : 9780898713947

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Statistical Case Studies for Industrial Process Improvement by Veronica Czitrom,Patrick D. Spagon Pdf

A selection of studies by professionals in the semiconductor industry illustrating the use of statistical methods to improve manufacturing processes.

Author : Jenny A. Baglivo
Publisher : SIAM
Page : 273 pages
File Size : 54,9 Mb
Release : 2005-01-01
Category : Mathematics
ISBN : 9780898715668

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Mathematica Laboratories for Mathematical Statistics by Jenny A. Baglivo Pdf

CD-ROM contains text, data, computations, and graphics.

Author : Jim Albert,Jay Bennett,James J. Cochran
Publisher : SIAM
Page : 298 pages
File Size : 45,6 Mb
Release : 2005-01-31
Category : Mathematics
ISBN : 9780898715873

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Anthology of Statistics in Sports by Jim Albert,Jay Bennett,James J. Cochran Pdf

Sport and statistics collide in this collection of articles (from American Statistical Association publications) on using statistics to analyze sport. Most of the articles will be accessible to readers with a general knowledge of statistics. New material from the editors and other notable contributors introduces each section of the book.