Author : Ata Mahjoubfar,Claire Lifan Chen,Bahram Jalali
Publisher : Springer
Page : 134 pages
File Size : 52,9 Mb
Release : 2017-04-19
Category : Technology & Engineering
ISBN : 9783319514482
Artificial Intelligence in Label-free Microscopy by Ata Mahjoubfar,Claire Lifan Chen,Bahram Jalali Pdf
This book introduces time-stretch quantitative phase imaging (TS-QPI), a high-throughput label-free imaging flow cytometer developed for big data acquisition and analysis in phenotypic screening. TS-QPI is able to capture quantitative optical phase and intensity images simultaneously, enabling high-content cell analysis, cancer diagnostics, personalized genomics, and drug development. The authors also demonstrate a complete machine learning pipeline that performs optical phase measurement, image processing, feature extraction, and classification, enabling high-throughput quantitative imaging that achieves record high accuracy in label -free cellular phenotypic screening and opens up a new path to data-driven diagnosis.