Artificial Intelligence In Oncology Drug Discovery And Development

Author : John Cassidy,Belle Taylor
Publisher : BoD – Books on Demand
Page : 194 pages
File Size : 46,9 Mb
Release : 2020-09-09
Category : Medical
ISBN : 9781789846898

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Artificial Intelligence in Oncology Drug Discovery and Development by John Cassidy,Belle Taylor Pdf

There exists a profound conflict at the heart of oncology drug development. The efficiency of the drug development process is falling, leading to higher costs per approved drug, at the same time personalised medicine is limiting the target market of each new medicine. Even as the global economic burden of cancer increases, the current paradigm in drug development is unsustainable. In this book, we discuss the development of techniques in machine learning for improving the efficiency of oncology drug development and delivering cost-effective precision treatment. We consider how to structure data for drug repurposing and target identification, how to improve clinical trials and how patients may view artificial intelligence.

Author : Harry Yang
Publisher : CRC Press
Page : 335 pages
File Size : 54,6 Mb
Release : 2022-10-04
Category : Business & Economics
ISBN : 9781000652673

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Data Science, AI, and Machine Learning in Drug Development by Harry Yang Pdf

The confluence of big data, artificial intelligence (AI), and machine learning (ML) has led to a paradigm shift in how innovative medicines are developed and healthcare delivered. To fully capitalize on these technological advances, it is essential to systematically harness data from diverse sources and leverage digital technologies and advanced analytics to enable data-driven decisions. Data science stands at a unique moment of opportunity to lead such a transformative change. Intended to be a single source of information, Data Science, AI, and Machine Learning in Drug Research and Development covers a wide range of topics on the changing landscape of drug R & D, emerging applications of big data, AI and ML in drug development, and the build of robust data science organizations to drive biopharmaceutical digital transformations. Features Provides a comprehensive review of challenges and opportunities as related to the applications of big data, AI, and ML in the entire spectrum of drug R & D Discusses regulatory developments in leveraging big data and advanced analytics in drug review and approval Offers a balanced approach to data science organization build Presents real-world examples of AI-powered solutions to a host of issues in the lifecycle of drug development Affords sufficient context for each problem and provides a detailed description of solutions suitable for practitioners with limited data science expertise

Author : Jianfeng Pei,Alex Zhavoronkov
Publisher : Frontiers Media SA
Page : 229 pages
File Size : 54,9 Mb
Release : 2021-11-16
Category : Science
ISBN : 9782889716494

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Artificial intelligence for Drug Discovery and Development by Jianfeng Pei,Alex Zhavoronkov Pdf

Topic editor Alex Zhavoronkov is the founder of Insilico Medicine, a company specializing in AI research. He is also a professor at the Buck Institute for Research on Aging. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Author : Nathan Brown
Publisher : Royal Society of Chemistry
Page : 425 pages
File Size : 40,6 Mb
Release : 2020-11-04
Category : Computers
ISBN : 9781839160547

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Artificial Intelligence in Drug Discovery by Nathan Brown Pdf

Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation. Providing a wealth of information from leading experts in the field this book is ideal for students, postgraduates and established researchers in both industry and academia.

Author : Mark Chang
Publisher : CRC Press
Page : 235 pages
File Size : 53,5 Mb
Release : 2020-05-12
Category : Business & Economics
ISBN : 9781000767308

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Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare by Mark Chang Pdf

Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science and statistics. While much of machine-learning is statistics-based, achievements in deep learning for image and language processing rely on computer science’s use of big data. Aimed at those with a statistical background who want to use their strengths in pursuing AI research, the book: · Covers broad AI topics in drug development, precision medicine, and healthcare. · Elaborates on supervised, unsupervised, reinforcement, and evolutionary learning methods. · Introduces the similarity principle and related AI methods for both big and small data problems. · Offers a balance of statistical and algorithm-based approaches to AI. · Provides examples and real-world applications with hands-on R code. · Suggests the path forward for AI in medicine and artificial general intelligence. As well as covering the history of AI and the innovative ideas, methodologies and software implementation of the field, the book offers a comprehensive review of AI applications in medical sciences. In addition, readers will benefit from hands on exercises, with included R code.

Author : Prashant Johri,Jitendra Kumar Verma,Sudip Paul
Publisher : Springer Nature
Page : 404 pages
File Size : 47,7 Mb
Release : 2020-05-04
Category : Technology & Engineering
ISBN : 9789811533570

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Applications of Machine Learning by Prashant Johri,Jitendra Kumar Verma,Sudip Paul Pdf

This book covers applications of machine learning in artificial intelligence. The specific topics covered include human language, heterogeneous and streaming data, unmanned systems, neural information processing, marketing and the social sciences, bioinformatics and robotics, etc. It also provides a broad range of techniques that can be successfully applied and adopted in different areas. Accordingly, the book offers an interesting and insightful read for scholars in the areas of computer vision, speech recognition, healthcare, business, marketing, and bioinformatics.

Author : Mullaicharam Bhupathyraaj,K. Reeta Vijaya Rani,Musthafa Mohamed Essa
Publisher : CRC Press
Page : 181 pages
File Size : 51,9 Mb
Release : 2023-11-23
Category : Medical
ISBN : 9781000994551

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Artificial intelligence in Pharmaceutical Sciences by Mullaicharam Bhupathyraaj,K. Reeta Vijaya Rani,Musthafa Mohamed Essa Pdf

This cutting-edge reference book discusses the intervention of artificial intelligence in the fields of drug development, modified drug delivery systems, pharmaceutical technology, and medical devices development. This comprehensive book includes an overview of artificial intelligence in pharmaceutical sciences and applications in the drug discovery and development process. It discusses the role of machine learning in the automated detection and sorting of pharmaceutical formulations. It covers nanosafety and the role of artificial intelligence in predicting potential adverse biological effects. FEATURES Includes lucid, step-by-step instructions to apply artificial intelligence and machine learning in pharmaceutical sciences Explores the application of artificial intelligence in nanosafety and prediction of potential hazards Covers application of artificial intelligence in drug discovery and drug development Reviews the role of artificial intelligence in assessment of pharmaceutical formulations Provides artificial intelligence solutions for experts in the pharmaceutical and medical devices industries This book is meant for academicians, students, and industry experts in pharmaceutical sciences, medicine, and pharmacology.

Author : Mark Chang
Publisher : Unknown
Page : 134 pages
File Size : 41,7 Mb
Release : 2020-09-09
Category : Electronic
ISBN : 9798684518881

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AI for Drug Development and Well-being by Mark Chang Pdf

Artificial intelligence (AI) is transforming the practice of medicine. It is helping doctors diagnose patients more accurately, predict treatment effects on individuals, and recommend better treatments. AI is also transforming the drug discovery and development process, helping pharmaceutical researchers to identify and design active drug candidates, and reducing the cost of the clinical testing phase. Recently, the FDA moved toward a new, tailored review framework for artificial intelligence-based medical devices (Gottlieb, April 2019).This book is intended for a broad readership: sufficiently straightforward for college freshmen and informative enough for researchers. Chapter 1 gives a gentle introduction to the five ML categories of learning: supervised, unsupervised, reinforcement, evolutionary and swarm intelligence. Chapters 2 through 6 discuss the key concepts of the main methods in each of the five AI categories and their applications in pharmaceutical research & development and healthcare. Chapter 7 provides a state-of-the-art review of AI applications in prescription drug discovery, development, pharmacovigilance, and healthcare. Chapter 8 discusses artificial general intelligence and its controversies, challenges, and likely future directions. A few equations are included to effectively deliver key concepts and 100 key references are cited to meet researchers' needs. The book is a simplified version of my previous book: Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare. Readers who want to get hands on experiences may explore the book with computer code in R.

Author : Ankur Saxena,Shivani Chandra
Publisher : Springer Nature
Page : 228 pages
File Size : 49,7 Mb
Release : 2021-05-06
Category : Science
ISBN : 9789811608117

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Artificial Intelligence and Machine Learning in Healthcare by Ankur Saxena,Shivani Chandra Pdf

This book reviews the application of artificial intelligence and machine learning in healthcare. It discusses integrating the principles of computer science, life science, and statistics incorporated into statistical models using existing data, discovering patterns in data to extract the information, and predicting the changes and diseases based on this data and models. The initial chapters of the book cover the practical applications of artificial intelligence for disease prognosis & management. Further, the role of artificial intelligence and machine learning is discussed with reference to specific diseases like diabetes mellitus, cancer, mycobacterium tuberculosis, and Covid-19. The chapters provide working examples on how different types of healthcare data can be used to develop models and predict diseases using machine learning and artificial intelligence. The book also touches upon precision medicine, personalized medicine, and transfer learning, with the real examples. Further, it also discusses the use of machine learning and artificial intelligence for visualization, prediction, detection, and diagnosis of Covid -19. This book is a valuable source of information for programmers, healthcare professionals, and researchers interested in understanding the applications of artificial intelligence and machine learning in healthcare.

Author : Feng Zhu,Yu Zong Chen,Weiwei Xue
Publisher : Frontiers Media SA
Page : 218 pages
File Size : 52,5 Mb
Release : 2021-08-19
Category : Science
ISBN : 9782889712007

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Target Discovery for Anticancer Therapy Facilitated by Artificial Intelligence by Feng Zhu,Yu Zong Chen,Weiwei Xue Pdf

Author : Fahima Dilnawaz,Ajit Kumar Behura
Publisher : Bentham Science Publishers
Page : 110 pages
File Size : 49,6 Mb
Release : 2022-05-31
Category : Technology & Engineering
ISBN : 9789815050578

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Artificial Intelligence Based Cancer Nanomedicine: Diagnostics, Therapeutics and Bioethics by Fahima Dilnawaz,Ajit Kumar Behura Pdf

Nanomedicine is evolving with novel drug formulations devised for multifunctional approaches towards diagnostics ad therapeutics. Nanomedicine-based drug therapy is normally explored at a fixed dose. The drug action is time-dependent, dose-dependent and patient-specific. To overcome challenges of nanomedicine testing, artificial intelligence (AI) serves as a helping tool for optimizing the drug and dose parameters. Real time conversions between these two features enables upgradation of patient data acquisition and improved design of nanomaterials. In this scenario, AI-based pattern analysis and algorithms models can greatly improve accuracy of diagnostics and therapeutics. This book gives a comprehensive explanation of the role of machine learning and artificial intelligence in cancer nanomedicine. It presents 10 chapters that cover multiple dimensions of the subject. These dimensions are: - The need of AI and ML in designing new cancer drugs - Application of AI in cancer drug design - AI-based drug delivery models for cancer drugs - Diagnostic applications of AI - Intelligent nanosensors for biomarker profiling - Predictive models for metastatic cancer - Cancer nanotheranostics - Ethics of AI in medicine Contributions have been made by 16 researchers who are experts in pharmacology and drug design. The contents of the book bridge knowledge gaps between the fields of biomedical engineering, pharmacology and clinical medicine, with a focus on cancer treatment. The book serves as a reference for scholars learning about cancer diagnostics and therapeutics. Biomedical engineers who are involved in healthcare projects will also find the concepts and techniques highlighted in the book informative for understanding modern computer-based approaches used to solve clinical problems.

Author : Anil K. Philip,Aliasgar Shahiwala,Mamoon Rashid,Md Faiyazuddin
Publisher : Academic Press
Page : 644 pages
File Size : 43,8 Mb
Release : 2023-03-27
Category : Computers
ISBN : 9780323903738

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A Handbook of Artificial Intelligence in Drug Delivery by Anil K. Philip,Aliasgar Shahiwala,Mamoon Rashid,Md Faiyazuddin Pdf

A Handbook of Artificial Intelligence in Drug Delivery explores the use of Artificial Intelligence (AI) in drug delivery strategies. The book covers pharmaceutical AI and drug discovery challenges, Artificial Intelligence tools for drug research, AI enabled intelligent drug delivery systems and next generation novel therapeutics, broad utility of AI for designing novel micro/nanosystems for drug delivery, AI driven personalized medicine and Gene therapy, 3D Organ printing and tissue engineering, Advanced nanosystems based on AI principles (nanorobots, nanomachines), opportunities and challenges using artificial intelligence in ADME/Tox in drug development, commercialization and regulatory perspectives, ethics in AI, and more. This book will be useful to academic and industrial researchers interested in drug delivery, chemical biology, computational chemistry, medicinal chemistry and bioinformatics. The massive time and costs investments in drug research and development necessitate application of more innovative techniques and smart strategies. Focuses on the use of Artificial Intelligence in drug delivery strategies and future impacts Provides insights into how artificial intelligence can be effectively used for the development of advanced drug delivery systems Written by experts in the field of advanced drug delivery systems and digital health

Author : Shai Ben- David,Giuseppe Curigliano,David Koff,Barbara Alicja Jereczek-Fossa,Davide La Torre,Gabriella Pravettoni
Publisher : Elsevier
Page : 296 pages
File Size : 41,6 Mb
Release : 2024-03-14
Category : Computers
ISBN : 9780443136726

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Artificial Intelligence for Medicine by Shai Ben- David,Giuseppe Curigliano,David Koff,Barbara Alicja Jereczek-Fossa,Davide La Torre,Gabriella Pravettoni Pdf

Artificial Intelligence for Medicine: An Applied Reference for Methods and Applications introduces readers to the methodology and AI/ML algorithms as well as cutting-edge applications to medicine, such as cancer, precision medicine, critical care, personalized medicine, telemedicine, drug discovery, molecular characterization, and patient mental health. Research in medicine and tailored clinical treatment are being quickly transformed by artificial intelligence (AI) and machine learning (ML). The content in this book is tailored to the reader's needs in terms of both type and fundamentals. It covers the current ethical issues and potential developments in this field. Artificial Intelligence for Medicine is beneficial for academics, professionals in the IT industry, educators, students, and anyone else involved in the use and development of AI in the medical field. Covers the basic concepts of Artificial Intelligence and Machine Learning, methods and practices, and advanced topics and applications to clinical and precision medicine Presents readers with an understanding of how AI is revolutionizing medicine by demonstrating the applications of computational intelligence to the field, along with an awareness of how AI can improve upon traditional medical structures Provides researchers, practitioners, and project stakeholders with a complete guide for applying AI techniques in their projects and solutions

Author : Nathan Brown
Publisher : Royal Society of Chemistry
Page : 425 pages
File Size : 44,9 Mb
Release : 2020-11-12
Category : Computers
ISBN : 9781788015479

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Artificial Intelligence in Drug Discovery by Nathan Brown Pdf

Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation.

Author : Stephanie K. Ashenden
Publisher : Academic Press
Page : 266 pages
File Size : 54,5 Mb
Release : 2021-04-23
Category : Computers
ISBN : 9780128204498

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The Era of Artificial Intelligence, Machine Learning, and Data Science in the Pharmaceutical Industry by Stephanie K. Ashenden Pdf

The Era of Artificial Intelligence, Machine Learning and Data Science in the Pharmaceutical Industry examines the drug discovery process, assessing how new technologies have improved effectiveness. Artificial intelligence and machine learning are considered the future for a wide range of disciplines and industries, including the pharmaceutical industry. In an environment where producing a single approved drug costs millions and takes many years of rigorous testing prior to its approval, reducing costs and time is of high interest. This book follows the journey that a drug company takes when producing a therapeutic, from the very beginning to ultimately benefitting a patient’s life. This comprehensive resource will be useful to those working in the pharmaceutical industry, but will also be of interest to anyone doing research in chemical biology, computational chemistry, medicinal chemistry and bioinformatics. Demonstrates how the prediction of toxic effects is performed, how to reduce costs in testing compounds, and its use in animal research Written by the industrial teams who are conducting the work, showcasing how the technology has improved and where it should be further improved Targets materials for a better understanding of techniques from different disciplines, thus creating a complete guide