Asymmetric Synthesis Of Three Membered Rings

Author : Hélène Pellissier,Alessandra Lattanzi,Renato Dalpozzo
Publisher : John Wiley & Sons
Page : 606 pages
File Size : 51,9 Mb
Release : 2017-06-19
Category : Science
ISBN : 9783527341146

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Asymmetric Synthesis of Three-Membered Rings by Hélène Pellissier,Alessandra Lattanzi,Renato Dalpozzo Pdf

The first handbook to focus on the asymmetric synthesis of different types of three-membered rings. The outstanding and experienced authors have an excellent international reputation and cover cyclopropanes, epoxides and aziridines as well as chiral oxaziridines in equal measure. To this end, they describe in detail different synthetic approaches starting with chiral substrates as well as the application of chiral metal- or organocatalysts. Furthermore, methods for the kinetic resolution of initially racemic products are treated alongside recent advances and novel developments in established techniques for the synthesis of three-membered rings. With its structured composition this is of high interest to scientists in methodological and natural product synthesis as well as those in industrial and pharmaceutical chemistry.

Author : Navjeet Kaur
Publisher : Elsevier
Page : 328 pages
File Size : 48,6 Mb
Release : 2024-01-15
Category : Science
ISBN : 9780443135842

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3-Membered Heterocycle Synthesis by Navjeet Kaur Pdf

3-membered heterocyclic rings offer an unusual combination of synthetic flexibility, reactivity, and atom economy. The main challenge for synthetic chemists, both in academia and industry, is the search for efficient approaches to target molecules. This book presents several methodologies for the synthesis of three-membered heterocyclic compounds and the readers will defiantly gain knowledge about the topic. With Three-Membered Heterocycle Synthesis, readers have detailed information about the synthesis of three-membered heterocyclic compounds. It comprehensively describes three-membered heterocyclic compounds synthesis, allowing the audience to quickly assess possible synthetic approaches. Covers the applications of three-membered heterocycles Includes comprehensive descriptions of heterocycle synthesis Highlights methodologies for the synthesis of three-membered heterocycles Analyzes several types and families of compounds, with a large set of recent examples in the field

Author : Sophie Bertilsson
Publisher : Uppsala Universitet
Page : 56 pages
File Size : 41,9 Mb
Release : 2001
Category : Science
ISBN : 9155450946

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Asymmetric Formation and Isomerization of Three-membered Rings by Sophie Bertilsson Pdf

Author : Benito Alcaide,Pedro Almendros
Publisher : Elsevier Inc. Chapters
Page : 550 pages
File Size : 40,5 Mb
Release : 2013-09-06
Category : Science
ISBN : 9780128056172

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Progress in Heterocyclic Chemistry by Benito Alcaide,Pedro Almendros Pdf

The review covers work published in the calendar year 2012. The synthesis of four-membered oxygen- and nitrogen-containing heterocycles is reviewed. New developments in the reaction chemistry of four-membered heterocycles, especially β-lactams, are covered.

Author : Jacques Royer
Publisher : John Wiley & Sons
Page : 425 pages
File Size : 41,5 Mb
Release : 2009-08-04
Category : Science
ISBN : 9783527625512

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Asymmetric Synthesis of Nitrogen Heterocycles by Jacques Royer Pdf

Here, all aspects of the topic are presented in a compact manner. The book is clearly structured, and divided into two sections -- asymmetric synthesis of heterocycles containing only one nitrogen and that of those with more than one nitrogen as a heteroatom -- such that the necessary information may be found at a glance. The international team of authors provides important experimental procedures, including industrial applications. Essential for synthetic chemists in pharmaceutical and agrochemical chemistry.

Author : Janine Cossy
Publisher : Springer
Page : 288 pages
File Size : 48,9 Mb
Release : 2014-03-14
Category : Science
ISBN : 9783642414732

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Synthesis of Saturated Oxygenated Heterocycles I by Janine Cossy Pdf

The series Topics in Heterocyclic Chemistry presents critical reviews on present and future trends in the research of heterocyclic compounds. Overall the scope is to cover topics dealing with all areas within heterocyclic chemistry, both experimental and theoretical, of interest to the general heterocyclic chemistry community. The series consists of topic related volumes edited by renowned editors with contributions of experts in the field.

Author : Stephen C. Bergmeier,David J. Lapinsky
Publisher : Elsevier Inc. Chapters
Page : 550 pages
File Size : 42,9 Mb
Release : 2013-09-06
Category : Science
ISBN : 9780128056165

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Progress in Heterocyclic Chemistry by Stephen C. Bergmeier,David J. Lapinsky Pdf

This chapter covers the chemistry of three-membered heterocycles, epoxides, aziridines, azirines, and oxaziridines for the calendar year 2012. For each of the different three-membered heterocycles, a listing of new methods of synthesis and new examples of reactions are presented. This review is not comprehensive for 2012 but covers methods and reactions that should be synthetically useful for the practicing chemist and those interested in the study of three-membered heterocyclic ring systems.

Author : P. Andrew Evans
Publisher : Thieme
Page : 1172 pages
File Size : 51,5 Mb
Release : 2014-05-14
Category : Science
ISBN : 9783131789617

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Science of Synthesis: Stereoselective Synthesis Vol. 3 by P. Andrew Evans Pdf

The major emphasis here is on enantioselective reactions using asymmetric catalysts. Examples from the total synthesis of various natural and unnatural targets validates the utility of the synthetic methods. Specific topics discussed: cycloaddition, cycloisomerization and sigmatropic rearrangement reactions, allylic and carbonyl functionalization reactions, metal-catalyzed cross-coupling reactions, desymmetrization, fluorination, polymerization and sulfide oxidation reactions. This volume is part of a 3-volume set: Science of Synthesis Stereoselective Synthesis Workbench Edition Further information about Stereoselective Synthesis (including sample pages and the table of contents)

Author : Gautam Patel,Vraj R. Shah,Tuan Anh Nguyen,Kalim Deshmukh
Publisher : Elsevier
Page : 660 pages
File Size : 44,5 Mb
Release : 2024-06-28
Category : Technology & Engineering
ISBN : 9780443223259

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Spirooxindole by Gautam Patel,Vraj R. Shah,Tuan Anh Nguyen,Kalim Deshmukh Pdf

Modern advances in organic synthesis require compouds having attractive properties with high percentage of yield. Spirooxindole examines the current state of the art, recent progress and new challenges associated with the development of spirooxindole derivatives for various medicinal applications. Owing to their exceptional properties, these compounds can be used in vaious fields, including chemical and pharma industries, and in clinical research. This book has chapters written by experts in several different areas. It serves as a useful reference book for scientists, industrial practitioners, graduate students, and other professionals in the field of hetrocyclic chemistry, medicinal chemistry, organic synthesis clinical research and chemical sciences.The growing interest among the academics and industrial researchers in the field of organic chemistry and medicinal chemistry is the driving force for the presentation of this edited book. Consolidates information on each aspect of this novel compound and its applications in various fields, covering the entire spectrum of up-to-date literature citations, current market, and patents Provides a comprehensive, in-depth description of spirooxindole derivatives as well as multipurpose scaffolds Highlights green synthesis and nanocatalysis Describes in-depth various medicinal applications Covers both synthesis and applications

Author : Wei Zhang,Berkeley W. Cue
Publisher : John Wiley & Sons
Page : 726 pages
File Size : 48,7 Mb
Release : 2018-03-19
Category : Science
ISBN : 9781119288169

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Green Techniques for Organic Synthesis and Medicinal Chemistry by Wei Zhang,Berkeley W. Cue Pdf

An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique’s features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, Second Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Author : Robert E. Gawley,Jeffrey Aube
Publisher : Elsevier
Page : 569 pages
File Size : 45,9 Mb
Release : 2012-07-16
Category : Science
ISBN : 9780080448602

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Principles of Asymmetric Synthesis by Robert E. Gawley,Jeffrey Aube Pdf

The world is chiral. Most of the molecules in it are chiral, and asymmetric synthesis is an important means by which enantiopure chiral molecules may be obtained for study and sale. The aim of this book is to present a detailed analysis of the factors that govern stereoselectivity in organic reactions.

Author : Alan Aitken,S. N. Kilenyi
Publisher : CRC Press
Page : 256 pages
File Size : 45,5 Mb
Release : 1992-12-30
Category : Science
ISBN : 0751401900

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Asymmetric Synthesis by Alan Aitken,S. N. Kilenyi Pdf

Asymmetric synthesis is one of the most important areas of research and development in synthetic organic chemistry, and has wide-ranging industrial applications. This introduction to the subject covers chirality, nomenclature and analytical methods of resolution. The main body of the text describes the principal methods available to the organic chemist wishing to synthesize chiral compounds. Case studies are included, and reference sections allow access to the relevant review and research literature. This book is written for organic chemists at postgraduate and advanced undergraduate level.

Author : Gerard Meurant
Publisher : Elsevier
Page : 329 pages
File Size : 50,7 Mb
Release : 1997-05-16
Category : Science
ISBN : 0080552005

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Advances in Asymmetric Synthesis by Gerard Meurant Pdf

Advances in Asymmetric Synthesis

Author : Andrei K. Yudin
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 45,6 Mb
Release : 2006-12-13
Category : Science
ISBN : 9783527607488

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Aziridines and Epoxides in Organic Synthesis by Andrei K. Yudin Pdf

Aziridines and epoxides are among the most widely used intermediates in organic synthesis, acting as precursors to complex molecules due to the strains incorporated in their skeletons. Besides their importance as reactive intermediates, many biologically active compounds also contain these three-membered rings. Filling a gap in the literature, this clearly structured book presents the much needed information in a compact and concise way. The renowned editor has succeeded in gathering together excellent authors to cover synthesis, applications, and the biological aspects in equal depth. Divided roughly equally between aziridines and epoxides, the twelve chapters discuss: * Synthesis of aziridines * Nucleophilic ring-opening of aziridines and epoxides * Organic synthesis with aziridine building blocks * Vinyl aziridines in organic synthesis * Diastereoselective aziridination reagents * Synthetic aspects of aziridinomitocene chemistry * Biosynthesis of biologically important aziridines * Organic catalysis of epoxide and aziridine ring formation * Metal-mediated synthesis of epoxides * Asymmetric epoxide ring opening chemistry * Epoxides in complex molecule synthesis * Biological activity of epoxide-containing molecules A high-quality reference manual for academic and industrial chemists alike.

Author : Alfred Hassner
Publisher : John Wiley & Sons
Page : 707 pages
File Size : 55,6 Mb
Release : 2009-09-15
Category : Science
ISBN : 9780470188705

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Small Ring Heterocycles, Volume 42, Part 1 by Alfred Hassner Pdf

The Chemistry of Heterocyclic Compounds, since its inception, has been recognized as a cornerstone of heterocyclic chemistry. Each volume attempts to discuss all aspects – properties, synthesis, reactions, physiological and industrial significance – of a specific ring system. To keep the series up-to-date, supplementary volumes covering the recent literature on each individual ring system have been published. Many ring systems (such as pyridines and oxazoles) are treated in distinct books, each consisting of separate volumes or parts dealing with different individual topics. With all authors are recognized authorities, the Chemistry of Heterocyclic Chemistry is considered worldwide as the indispensable resource for organic, bioorganic, and medicinal chemists.