Bacterial Integrative Mobile Genetic Elements

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Bacterial Integrative Mobile Genetic Elements

Adam P. Roberts,Peter Mullany
Bacterial Integrative Mobile Genetic Elements Book PDF

Author : Adam P. Roberts,Peter Mullany
Publisher : CRC Press
Page : 456 pages
File Size : 42,8 Mb
Release : 2022-03-07
Category : Science
ISBN : 9781000724707

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Bacterial Integrative Mobile Genetic Elements by Adam P. Roberts,Peter Mullany Pdf

As our understanding of mobile genetic elements continues to grow we are gaining a deeper appreciation of their importance in shaping the bacterial genome and in the properties they confer to their bacterial hosts. These include, but are by no means limited to, resistance to antibiotics, and heavy metals, toxin production and increased virulence, production of antibiotics and the ability to utilize a diverse range of metabolic substrates. We are also gaining an understanding of diversity of these elements and their interactions with each other; a property which continually complicates any attempt to classify them. We are learning more about the molecular mechanisms by which they translocate to new genomic sites both within genomes and between different bacteria. This book provides a timely, state of the art update on the properties of an important selection of different bacterial integrative mobile genetic elements and the myriad of different ways in which they move and influence the biology of the host bacterium. The chapters are all written by authors who have undertaken pioneering work in their respective fields, making this book vital reading for all who are interested in the biology of bacteria and the mobile elements they carry.

The Dynamic Bacterial Genome

Peter Mullany
The Dynamic Bacterial Genome Book PDF

Author : Peter Mullany
Publisher : Cambridge University Press
Page : 452 pages
File Size : 55,5 Mb
Release : 2005-09-26
Category : Medical
ISBN : 0521821576

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The Dynamic Bacterial Genome by Peter Mullany Pdf

"This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. Because genome rearrangements are so important in evolution, at least one of the chapters views the phenomenon from an evolutionary angle. This book provides the reader with a holistic view of genome rearrangements (i.e., studies on both the biological consequences of genome rearrangement and the mechanisms underlying these processes are presented)." "The book is written by leading research workers in the field and is aimed at final-year undergraduates, postgraduate and postdoctoral workers, and established biologists."--BOOK JACKET.

Mobile DNA III

Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne B. Sandmeyer
Mobile DNA III Book PDF

Author : Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne B. Sandmeyer
Publisher : John Wiley & Sons
Page : 1321 pages
File Size : 40,6 Mb
Release : 2020-07-24
Category : Science
ISBN : 9781555819217

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Mobile DNA III by Michael Chandler,Martin Gellert,Alan M. Lambowitz,Phoebe A. Rice,Suzanne B. Sandmeyer Pdf

An exploration of the raw power of genetic material to refashion itself to any purpose... Virtually all organisms contain multiple mobile DNAs that can move from place to place, and in some organisms, mobile DNA elements make up a significant portion of the genome. Mobile DNA III provides a comprehensive review of recent research, including findings suggesting the important role that mobile elements play in genome evolution and stability. Editor-in-Chief Nancy L. Craig assembled a team of multidisciplinary experts to develop this cutting-edge resource that covers the specific molecular mechanisms involved in recombination, including a detailed structural analysis of the enzymes responsible presents a detailed account of the many different recombination systems that can rearrange genomes examines the tremendous impact of mobile DNA in virtually all organisms Mobile DNA III is valuable as an in-depth supplemental reading for upper level life sciences students and as a reference for investigators exploring new biological systems. Biomedical researchers will find documentation of recent advances in understanding immune-antigen conflict between host and pathogen. It introduces biotechnicians to amazing tools for in vivo control of designer DNAs. It allows specialists to pick and choose advanced reviews of specific elements and to be drawn in by unexpected parallels and contrasts among the elements in diverse organisms. Mobile DNA III provides the most lucid reviews of these complex topics available anywhere.

DNA Traffic in the Environment

Hiromi Nishida,Taku Oshima
DNA Traffic in the Environment Book PDF

Author : Hiromi Nishida,Taku Oshima
Publisher : Springer
Page : 278 pages
File Size : 45,9 Mb
Release : 2019-02-21
Category : Science
ISBN : 9789811334115

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DNA Traffic in the Environment by Hiromi Nishida,Taku Oshima Pdf

This book comprehensively discusses our current understanding of the role and biological mechanisms of horizontal transfer of genetic elements in the environment, which has been important in the evolution of prokaryotes (archaea and bacteria). Horizontal transfer of genetic elements generates variations of prokaryotes and their genomes. Comparative studies of genomes revealed that it frequently occurred during archaeal and bacterial evolution. The book introduces a variety of studies related to horizontal gene transfer, gene silencing, plasmids, phages, transposons, and the emergence of microbes that degrade man-made xenobiotics and have antimicrobial resistance. Written by leading researchers in DNA traffic, the book is a valuable guide to horizontal transfer for both young scientists and experts in the field.

The Dynamic Bacterial Genome

Peter Mullany
The Dynamic Bacterial Genome Book PDF

Author : Peter Mullany
Publisher : Cambridge University Press
Page : 454 pages
File Size : 41,8 Mb
Release : 2010-02-04
Category : Science
ISBN : 9781139445504

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The Dynamic Bacterial Genome by Peter Mullany Pdf

The genetic information contained in DNA is not static, especially in bacterial DNA. It is capable of recombining with other DNA sequences and transferring to other bacteria. These processes allow bacteria to rapidly respond to their environment and are also important in production of disease and the spread of antibiotic resistance. This book is concerned with the mechanisms underlying these dynamic processes in bacterial DNA.

Horizontal Gene Pool

Christopher M. Thomas
Horizontal Gene Pool Book PDF

Author : Christopher M. Thomas
Publisher : CRC Press
Page : 459 pages
File Size : 54,9 Mb
Release : 2003-09-02
Category : Science
ISBN : 9780203304334

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Horizontal Gene Pool by Christopher M. Thomas Pdf

Bacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.

The Pangenome

Hervé Tettelin,Duccio Medini
The Pangenome Book PDF

Author : Hervé Tettelin,Duccio Medini
Publisher : Springer Nature
Page : 311 pages
File Size : 51,7 Mb
Release : 2020-04-30
Category : Science
ISBN : 9783030382810

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The Pangenome by Hervé Tettelin,Duccio Medini Pdf

This open access book offers the first comprehensive account of the pan-genome concept and its manifold implications. The realization that the genetic repertoire of a biological species always encompasses more than the genome of each individual is one of the earliest examples of big data in biology that opened biology to the unbounded. The study of genetic variation observed within a species challenges existing views and has profound consequences for our understanding of the fundamental mechanisms underpinning bacterial biology and evolution. The underlying rationale extends well beyond the initial prokaryotic focus to all kingdoms of life and evolves into similar concepts for metagenomes, phenomes and epigenomes. The book’s respective chapters address a range of topics, from the serendipitous emergence of the pan-genome concept and its impacts on the fields of microbiology, vaccinology and antimicrobial resistance, to the study of microbial communities, bioinformatic applications and mathematical models that tie in with complex systems and economic theory. Given its scope, the book will appeal to a broad readership interested in population dynamics, evolutionary biology and genomics.

Microbial Megaplasmids

Edward Schwartz
Microbial Megaplasmids Book PDF

Author : Edward Schwartz
Publisher : Springer Science & Business Media
Page : 348 pages
File Size : 45,5 Mb
Release : 2009-01-29
Category : Science
ISBN : 9783540854678

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Microbial Megaplasmids by Edward Schwartz Pdf

Megaplasmids are extrachromosomal genetic elements in the size range of 100 kb and larger. They are found in physiologically and phylogenetically diverse groups of bacteria and archaea. By definition, megaplasmids are not essential for the viability of their hosts under all growth conditions, but paradoxically many megaplasmids carry the genetic information for the defining and characteristic traits of the organism in which they reside. Microbial Megaplasmids reviews our knowledge of the extensively studied representatives, such as the catabolic plasmids of the pseudomonads, the rhizobial Sym plasmids, the Ti plasmids of the genus Agrobacterium and the giant enterobacterial virulence plasmids. It also presents snapshots of more recently discovered megaplasmids. The contribution of megaplasmids to the biology of their hosts is described, highlighting the interactions between megaplasmid and chromosomal genes.

Horizontal Gene Transfer in the Evolution of Pathogenesis

Michael Hensel,Herbert Schmidt
Horizontal Gene Transfer in the Evolution of Pathogenesis Book PDF

Author : Michael Hensel,Herbert Schmidt
Publisher : Cambridge University Press
Page : 335 pages
File Size : 43,9 Mb
Release : 2008-06-30
Category : Science
ISBN : 9781139472050

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Horizontal Gene Transfer in the Evolution of Pathogenesis by Michael Hensel,Herbert Schmidt Pdf

Horizontal gene transfer is a major driving force in the evolution of many bacterial pathogens. The development of high-throughput sequencing tools and more sophisticated genomic and proteomic techniques in recent years has resulted in a better understanding of this phenomenon. Written by leading experts in the field, this edited volume is aimed at graduate students and researchers and provides an overview of current knowledge relating to the evolution of microbial pathogenicity. This volume provides an overview of the mechanisms and biological consequences of the genome rearrangements resulting from horizontal gene transfer, in both prokaryotes and eukaryotes, as well as overviews of the key mobile genetic elements involved. Subsequent chapters focus on paradigms for the evolution of important bacterial pathogens, including Salmonella enterica, Streptococcus pneumoniae, and Staphylococcus aureus. The influence of socioeconomic parameters in the dissemination of transferable elements, such as antibiotic resistant genes in bacteria, is also discussed.

Type IV Secretion in Gram-Negative and Gram-Positive Bacteria

Steffen Backert,Elisabeth Grohmann
Type IV Secretion in Gram Negative and Gram Positive Bacteria Book PDF

Author : Steffen Backert,Elisabeth Grohmann
Publisher : Springer
Page : 345 pages
File Size : 42,8 Mb
Release : 2018-03-13
Category : Medical
ISBN : 9783319752419

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Type IV Secretion in Gram-Negative and Gram-Positive Bacteria by Steffen Backert,Elisabeth Grohmann Pdf

Type IV secretion systems (T4SSs) are highly versatile membrane-associated transporter machines used by Gram-negative and Gram-positive bacteria to deliver substrate molecules to a large variety of target cells. This volume summarizes our current knowledge of the large variety and structural diversity of T4SSs in pathogenic Escherichia, Agrobacterium, Legionella, Coxiella, Bartonella, Helicobacter, Enterococcus and other species. Divided into 13 chapters contributed by leading experts, it presents findings that significantly enhance our understanding of how various pathogens manipulate host cell functions to trigger bacterial uptake, promote intracellular growth, suppress defense mechanisms and of how bacteria spread antibiotic resistances, thus facilitating bacterial colonization and disease development. The book is an invaluable source of information for researchers and clinicians.

Transposable Elements

Heinz Saedler,Alfons Gierl
Transposable Elements Book PDF

Author : Heinz Saedler,Alfons Gierl
Publisher : Springer Science & Business Media
Page : 242 pages
File Size : 50,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9783642797958

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Transposable Elements by Heinz Saedler,Alfons Gierl Pdf

Most genes are lined up on chromosomes like pearls on a string. However, a certain class of genes differ by being highly mobile; and the mecha they are termed transposons. Their properties of transposition will be described in this book. nism is the rule, irregularities like a spot on a Where uniformity plain-coloured surface strike the eye. Thus the phenomenon of has long been a source of fascina variegation among organisms In plants, variegation is most easily recognised as irregulari tion. in pigment patterns on leaves, flowers and seeds, but other ties as leaf or flower form might also show characteristics such In 1588, such a variegation pattern was described in variegation. kernels of Zea mays by Jacob Theodor of Bergzabern, a village is so detailed that if south of Strasbourg. The report by Theodor one counts the different kernel phenotypes described it be is looking at a Mendelian segrega comes clear that the author had tion. It goes without saying that Latin-American Indians already bred such variegated material much earlier, but no descriptions have yet been uncovered. Meanwhile, genetically heritable variegation patterns have been described at many different loci in more than 34 different plant species.

Antibiotic Drug Resistance

José-Luis Capelo-Martínez,Gilberto Igrejas
Antibiotic Drug Resistance Book PDF

Author : José-Luis Capelo-Martínez,Gilberto Igrejas
Publisher : John Wiley & Sons
Page : 730 pages
File Size : 47,9 Mb
Release : 2019-09-24
Category : Medical
ISBN : 9781119282525

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Antibiotic Drug Resistance by José-Luis Capelo-Martínez,Gilberto Igrejas Pdf

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Mobile Genetic Elements

Wolfgang J. Miller,Pierre Capy
Mobile Genetic Elements Book PDF

Author : Wolfgang J. Miller,Pierre Capy
Publisher : Humana
Page : 0 pages
File Size : 44,6 Mb
Release : 2010-11-10
Category : Medical
ISBN : 161737301X

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Mobile Genetic Elements by Wolfgang J. Miller,Pierre Capy Pdf

Leading experts describe in step-by-step detail their most productive transposon-based methods and strategies for studying genome structure, function, and evolution. These readily reproducible techniques cover a wide range, including mutagenesis, transgenesis, gene silencing, and molecular systematics. Among the highlights are a series of DNA hybridization methods for analyzing the distribution and dynamics of mobile DNA at the hosts' genomic level, techniques for studying LTR retrotransposons in heterologous host systems, and mutagenesis protocols for investigating gene functions in a broad range of organisms. These cutting-edge methods offer investigators powerful genetic tools for dissecting the function of a specific gene, elaborating on the mechanisms leading to genetic change and diversity, and studying the evolutionary impact of mobile DNA on the biology and evolution of organisms.

Antimicrobial Resistance

World Health Organization
Antimicrobial Resistance Book PDF

Author : World Health Organization
Publisher : Unknown
Page : 232 pages
File Size : 41,5 Mb
Release : 2014
Category : Medical
ISBN : 9241564741

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Antimicrobial Resistance by World Health Organization Pdf

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Snyder and Champness Molecular Genetics of Bacteria

Tina M. Henkin,Joseph E. Peters
Snyder and Champness Molecular Genetics of Bacteria Book PDF

Author : Tina M. Henkin,Joseph E. Peters
Publisher : John Wiley & Sons
Page : 642 pages
File Size : 47,6 Mb
Release : 2020-10-27
Category : Science
ISBN : 9781555819750

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Snyder and Champness Molecular Genetics of Bacteria by Tina M. Henkin,Joseph E. Peters Pdf

The single most comprehensive and authoritative textbook on bacterial molecular genetics Snyder & Champness Molecular Genetics of Bacteria is a new edition of a classic text, updated to address the massive advances in the field of bacterial molecular genetics and retitled as homage to the founding authors. In an era experiencing an avalanche of new genetic sequence information, this updated edition presents important experiments and advanced material relevant to current applications of molecular genetics, including conclusions from and applications of genomics; the relationships among recombination, replication, and repair and the importance of organizing sequences in DNA; the mechanisms of regulation of gene expression; the newest advances in bacterial cell biology; and the coordination of cellular processes during the bacterial cell cycle. The topics are integrated throughout with biochemical, genomic, and structural information, allowing readers to gain a deeper understanding of modern bacterial molecular genetics and its relationship to other fields of modern biology. Although the text is centered on the most-studied bacteria, Escherichia coli and Bacillus subtilis, many examples are drawn from other bacteria of experimental, medical, ecological, and biotechnological importance. The book's many useful features include Text boxes to help students make connections to relevant topics related to other organisms, including humans A summary of main points at the end of each chapter Questions for discussion and independent thought A list of suggested readings for background and further investigation in each chapter Fully illustrated with detailed diagrams and photos in full color A glossary of terms highlighted in the text While intended as an undergraduate or beginning graduate textbook, Molecular Genetics of Bacteria is an invaluable reference for anyone working in the fields of microbiology, genetics, biochemistry, bioengineering, medicine, molecular biology, and biotechnology. "This is a marvelous textbook that is completely up-to-date and comprehensive, but not overwhelming. The clear prose and excellent figures make it ideal for use in teaching bacterial molecular genetics." —Caroline Harwood, University of Washington