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Author : Stephan Fuchs,Guido Werner,Se-Ran Jun,Edward Feil,Kristin Hegstad,Yang Wang
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 55,5 Mb
Release : 2022-08-02
Category : Science
ISBN : 9782889766802
Author : Debmalya Barh,Siomar C. Soares,Sandeep Tiwari,Vasco Ariston De Car Azevedo
Publisher : Academic Press
Page : 476 pages
File Size : 48,9 Mb
Release : 2020-03-06
Category : Science
ISBN : 9780128170779
Pan-genomics: Applications, Challenges, and Future Prospects covers current approaches, challenges and future prospects of pan-genomics. The book discusses bioinformatics tools and their applications and focuses on bacterial comparative genomics in order to leverage the development of precise drugs and treatments for specific organisms. The book is divided into three sections: the first, an "overview of pan-genomics and common approaches, brings the main concepts and current approaches on pan-genomics research; the second, “case studies in pan-genomics, thoroughly discusses twelve case, and the last, “current approaches and future prospects in pan-multiomics , encompasses the developments on omics studies to be applied on bacteria related studies. This book is a valuable source for bioinformaticians, genomics researchers and several members of biomedical field interested in understanding further bacterial organisms and their relationship to human health. Covers the entire spectrum of pangenomics, highlighting the use of specific approaches, case studies and future perspectives Discusses current bioinformatics tools and strategies for exploiting pangenomics data Presents twelve case studies with different organisms in order to provide the audience with real examples of pangenomics applicability
Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publisher : National Academies Press
Page : 189 pages
File Size : 51,5 Mb
Release : 2019-01-05
Category : Technology & Engineering
ISBN : 9780309465182
Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.
Author : Mark J. Pallen,Karen E. Nelson,Gail M. Preston
Publisher : Unknown
Page : 488 pages
File Size : 48,8 Mb
Release : 2007
Category : Medical
ISBN : UOM:39015074270326
This landmark volume details progress in the fast-changing world of bacterial genomics and it includes contributions from a team of over forty world-renowned authors.
Author : National Research Council,Division on Earth and Life Studies,Board on Life Sciences,Committee on Metagenomics: Challenges and Functional Applications
Publisher : National Academies Press
Page : 170 pages
File Size : 49,7 Mb
Release : 2007-06-24
Category : Science
ISBN : 9780309106764
Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.
Author : Shalini Rai,Ram Prasad
Publisher : Elsevier
Page : 302 pages
File Size : 44,8 Mb
Release : 2023-02-21
Category : Technology & Engineering
ISBN : 9780323985314
New and Future Developments in Microbial Biotechnology and Bioengineering: Trichoderma for Biotechnological Applications: Current Insights and Future Prospects includes the most recent advances in Trichoderma based research. The book emphasizes the use of modern biotechnological and molecular tools such as the identification of Trichoderma, the development of diagnostic markers, and genome mapping and next generation sequencing based approaches. Chapters discuss a variety of applications and illustrations, including the biology and biodiversity of Trichoderma, biotic and abiotic stresses, plant health, disease management, crop improvement, industrial and commercial products, and more. The book includes various applications, making it useful for biotechnologists, biochemical engineers, biochemists, plant breeders, soil microbiologist, agronomists and researchers interested in sustainable agriculture practices. Offers a one-stop resource on the topic of Trichoderma and their biotechnological applications in plant disease, sustainable agriculture, plant health, and in industrial commercial products Addresses the role of Trichoderma to combat abiotic and biotic stress, mechanisms involved genes and their role in plant health improvement Emphasizes the use of modern biotechnological and molecular tools for the identification of Trichoderma, development of diagnostic markers, genome mapping, and next generation sequencing based approaches
Author : Michel Tibayrenc
Publisher : Elsevier
Page : 773 pages
File Size : 49,7 Mb
Release : 2010-12-17
Category : Medical
ISBN : 9780123848901
Genetics and Evolution of Infectious Diseases is at the crossroads between two major scientific fields of the 21st century: evolutionary biology and infectious diseases. The genomic revolution has upset modern biology and has revolutionized our approach to ancient disciplines such as evolutionary studies. In particular, this revolution is profoundly changing our view on genetically driven human phenotypic diversity, and this is especially true in disease genetic susceptibility. Infectious diseases are indisputably the major challenge of medicine. When looking globally, they are the number one killer of humans and therefore the main selective pressure exerted on our species. Even in industrial countries, infectious diseases are now far less under control than 20 years ago. The first part of this book covers the main features and applications of modern technologies in the study of infectious diseases. The second part provides detailed information on a number of the key infectious diseases such as malaria, SARS, avian flu, HIV, tuberculosis, nosocomial infections and a few other pathogens that will be taken as examples to illustrate the power of modern technologies and the value of evolutionary approaches. Takes an integrated approach to infectious diseases Includes contributions from leading authorities Provides the latest developments in the field
Author : Jean Marie François,Shota Atsumi
Publisher : Frontiers Media SA
Page : 194 pages
File Size : 43,8 Mb
Release : 2023-05-05
Category : Science
ISBN : 9782832522707
Author : Tulasi Satyanarayana,Bhavdish Narain Johri,Subrata Kumar Das
Publisher : Springer
Page : 635 pages
File Size : 54,9 Mb
Release : 2019-07-17
Category : Science
ISBN : 9789811383151
This book discusses microbial diversity in various habitats and environments, its role in ecosystem maintenance, and its potential applications (e.g. biofertilizers, biocatalysts, antibiotics, other bioactive compounds, exopolysaccharides etc.). The respective chapters, all contributed by renowned experts, offer cutting-edge information in the fields of microbial ecology and biogeography. The book explains the reasons behind the occurrence of various biogeographies and highlights recent tools (e.g. metagenomics) that can aid in biogeography studies by providing information on nucleic acid sequence data, thereby directly identifying microorganisms in various habitats and environments. In turn, the book describes how human intervention results in depletion of biodiversity, and how numerous hotspots are now losing their endemic biodiversity, resulting in the loss of many ecologically important microorganisms. In closing, the book underscores the importance of microbial diversity for sustainable ecosystems.
Author : Rossana Coda,Ana Gomes,Carlo Giuseppe Rizzello,Andrea Gianotti
Publisher : Frontiers Media SA
Page : 146 pages
File Size : 44,9 Mb
Release : 2020-10-23
Category : Science
ISBN : 9782889660926
This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.
Author : J.P. Gustafson,J. Tayler,G. Stacey
Publisher : Springer Science & Business Media
Page : 222 pages
File Size : 46,8 Mb
Release : 2008-02-12
Category : Medical
ISBN : 9780387767239
This title develops from the 24th Stadler symposium. It explores the general theme "GENOME EXPLOITATION: Data Mining the Genomes". The idea behind the theme is to discuss and illustrate how scientists are going to characterize and make use of the massive amount of information being accumulated about plant and animal genomes. The book presents a state-of-the-art picture on mining the Genome databases. Its chapters are authored by key stars in the field.
Author : Vincent A. Fischetti,Richard P. Novick,Joseph J. Ferretti,Daniel A. Portnoy,Mirian Braunstein,Julian I. Rood
Publisher : John Wiley & Sons
Page : 2803 pages
File Size : 50,8 Mb
Release : 2019-10-01
Category : Science
ISBN : 9781683672876
Gram-positive bacteria, lacking an outer membrane and related secretory systems and having a thick peptidoglycan, have developed novel approaches to pathogenesis by acquiring (among others) a unique family of surface proteins, toxins, enzymes, and prophages. For the new edition, the editors have enhanced this fully researched compendium of Gram-positive bacterial pathogens by including new data generated using genomic sequencing as well as the latest knowledge on Gram-positive structure and mechanisms of antibiotic resistance and theories on the mechanisms of Gram-positive bacterial pathogenicity. This edition emphasizes streptococci, staphylococci, listeria, and spore-forming pathogens, with chapters written by many of the leading researchers in these areas. The chapters systematically dissect these organisms biologically, genetically, and immunologically, in an attempt to understand the strategies used by these bacteria to cause human disease. “This textbook comprises a superb collection of scientific knowledge making it a must-read for any graduate student, medical doctor, or investigator studying these gram-positive bacteria and inspiring future imaginations of biological knowledge.” - William R. Jacobs, Jr., PhD, Professor Microbiology & Immunology, Albert Einstein College of Medicine
Author : Ali Asghar Rastegari,Ajar Nath Yadav,Neelam Yadav
Publisher : Elsevier
Page : 366 pages
File Size : 55,6 Mb
Release : 2020-05-16
Category : Technology & Engineering
ISBN : 9780128205273
New and Future Developments in Microbial Biotechnology and Bioengineering: Trends of Microbial Biotechnology for Sustainable Agriculture and Biomedicine Systems: Diversity and Functional Perspectives describes how specific techniques can be used to generalize the metabolism of bacteria that optimize biologic improvement strategies and bio-transport processes. Microbial biotechnology focuses on microbes of agricultural, environmental, industrial, and clinical significance. This volume discusses several methods based on molecular genetics, systems, and biology of synthetic, genomic, proteomic, and metagenomics. Recent developments in our understanding of the role of microbes in sustainable agriculture and biotechnology have created a highly potential research area. The soil and plant microbiomes have a significant role in plant growth promotion, crop yield, soil health and fertility for sustainable developments. The microbes provide nutrients and stimulate plant growth through different mechanisms, including solubilization of phosphorus, potassium, and zinc; biological nitrogen fixation; production of siderophore, ammonia, HCN and other secondary metabolites which are antagonistic against pathogenic microbes. This new book provides an indispensable reference source for engineers/bioengineers, biochemists, biotechnologists, microbiologists, agrochemists, and researchers who want to know about the unique properties of this microbe and explore its sustainable agriculture future applications. Introduces the principles of microbial biotechnology and its application in plant growth and soil health for sustainable agriculture Explores various plant microbiomes and their beneficial impact on plant growth for crop improvement Explains the mechanisms of plant-microbe interaction and plant growth promotion Includes current applications of microbial consortium for enhance production of crop in eco-friendly manners
Author : Institute of Medicine,Board on Global Health,Committee on Emerging Microbial Threats to Health in the 21st Century
Publisher : National Academies Press
Page : 397 pages
File Size : 55,8 Mb
Release : 2003-08-25
Category : Medical
ISBN : 9780309185547
Infectious diseases are a global hazard that puts every nation and every person at risk. The recent SARS outbreak is a prime example. Knowing neither geographic nor political borders, often arriving silently and lethally, microbial pathogens constitute a grave threat to the health of humans. Indeed, a majority of countries recently identified the spread of infectious disease as the greatest global problem they confront. Throughout history, humans have struggled to control both the causes and consequences of infectious diseases and we will continue to do so into the foreseeable future. Following up on a high-profile 1992 report from the Institute of Medicine, Microbial Threats to Health examines the current state of knowledge and policy pertaining to emerging and re-emerging infectious diseases from around the globe. It examines the spectrum of microbial threats, factors in disease emergence, and the ultimate capacity of the United States to meet the challenges posed by microbial threats to human health. From the impact of war or technology on disease emergence to the development of enhanced disease surveillance and vaccine strategies, Microbial Threats to Health contains valuable information for researchers, students, health care providers, policymakers, public health officials. and the interested public.
Author : Andrzej Gorski,Petar Knezevic,Naomi Sulinger Hoyle,Shigenobu Matsuzaki
Publisher : Frontiers Media SA
Page : 177 pages
File Size : 43,5 Mb
Release : 2021-08-02
Category : Science
ISBN : 9782889711260
This Research Topic is dedicated to Prof. Elisabeth Kutter on the occasion of her 80th birthday. Dr. Kutter’s career as a phage scientist has extended nearly 60 years. She has been a pioneer as a woman in science. She started to work with phage at the University of Rochester, New York working with Dr. Wiberg on radioisotopes making excellent progress in the field – progress which was even cited in Luria’s 1969 Nobel Prize talk. Betty first encountered phage therapy during a visit to Georgia in 1990 which was part of a longer stay in the former Soviet Union under a US-USSR research exchange program. Dr. Kutter was one of the first Americans to advocate for phage therapy in the post antibiotic era. Betty started hosting the Evergreen International Phage meetings in Olympia, Washington, from 1975 onward, which helped to develop a strong phage community with participation increasing over the years to 350 at the 23 rd biannual last year. Betty continues to be an active member in the phage community, sharing her experience and working with all of us toward her ultimate goal of making phage therapy available worldwide thus reducing the burden caused by antibiotic resistant bacterial infections.