Barriers To Bioweapons

Author : Sonia Ben Ouagrham-Gormley
Publisher : Cornell University Press
Page : 237 pages
File Size : 44,5 Mb
Release : 2014-12-15
Category : Political Science
ISBN : 9780801471926

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Barriers to Bioweapons by Sonia Ben Ouagrham-Gormley Pdf

In both the popular imagination and among lawmakers and national security experts, there exists the belief that with sufficient motivation and material resources, states or terrorist groups can produce bioweapons easily, cheaply, and successfully. In Barriers to Bioweapons, Sonia Ben Ouagrham-Gormley challenges this perception by showing that bioweapons development is a difficult, protracted, and expensive endeavor, rarely achieving the expected results whatever the magnitude of investment. Her findings are based on extensive interviews she conducted with former U.S. and Soviet-era bioweapons scientists and on careful analysis of archival data and other historical documents related to various state and terrorist bioweapons programs.Bioweapons development relies on living organisms that are sensitive to their environment and handling conditions, and therefore behave unpredictably. These features place a greater premium on specialized knowledge. Ben Ouagrham-Gormley posits that lack of access to such intellectual capital constitutes the greatest barrier to the making of bioweapons. She integrates theories drawn from economics, the sociology of science, organization, and management with her empirical research. The resulting theoretical framework rests on the idea that the pace and success of a bioweapons development program can be measured by its ability to ensure the creation and transfer of scientific and technical knowledge. The specific organizational, managerial, social, political, and economic conditions necessary for success are difficult to achieve, particularly in covert programs where the need to prevent detection imposes managerial and organizational conditions that conflict with knowledge production.

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology
Publisher : National Academies Press
Page : 189 pages
File Size : 49,6 Mb
Release : 2019-01-05
Category : Technology & Engineering
ISBN : 9780309465182

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Biodefense in the Age of Synthetic Biology by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Board on Chemical Sciences and Technology,Committee on Strategies for Identifying and Addressing Potential Biodefense Vulnerabilities Posed by Synthetic Biology Pdf

Scientific advances over the past several decades have accelerated the ability to engineer existing organisms and to potentially create novel ones not found in nature. Synthetic biology, which collectively refers to concepts, approaches, and tools that enable the modification or creation of biological organisms, is being pursued overwhelmingly for beneficial purposes ranging from reducing the burden of disease to improving agricultural yields to remediating pollution. Although the contributions synthetic biology can make in these and other areas hold great promise, it is also possible to imagine malicious uses that could threaten U.S. citizens and military personnel. Making informed decisions about how to address such concerns requires a realistic assessment of the capabilities that could be misused. Biodefense in the Age of Synthetic Biology explores and envisions potential misuses of synthetic biology. This report develops a framework to guide an assessment of the security concerns related to advances in synthetic biology, assesses the levels of concern warranted for such advances, and identifies options that could help mitigate those concerns.

Author : Gregory D. Koblentz
Publisher : Cornell University Press
Page : 272 pages
File Size : 52,6 Mb
Release : 2011-05-16
Category : Political Science
ISBN : 9780801457661

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Living Weapons by Gregory D. Koblentz Pdf

"Biological weapons are widely feared, yet rarely used. Biological weapons were the first weapon prohibited by an international treaty, yet the proliferation of these weapons increased after they were banned in 1972. Biological weapons are frequently called 'the poor man's atomic bomb,' yet they cannot provide the same deterrent capability as nuclear weapons. One of my goals in this book is to explain the underlying principles of these apparent paradoxes."—from Living Weapons Biological weapons are the least well understood of the so-called weapons of mass destruction. Unlike nuclear and chemical weapons, biological weapons are composed of, or derived from, living organisms. In Living Weapons, Gregory D. Koblentz provides a comprehensive analysis of the unique challenges that biological weapons pose for international security. At a time when the United States enjoys overwhelming conventional military superiority, biological weapons have emerged as an attractive means for less powerful states and terrorist groups to wage asymmetric warfare. Koblentz also warns that advances in the life sciences have the potential to heighten the lethality and variety of biological weapons. The considerable overlap between the equipment, materials and knowledge required to develop biological weapons, conduct civilian biomedical research, and develop biological defenses creates a multiuse dilemma that limits the effectiveness of verification, hinders civilian oversight, and complicates threat assessments. Living Weapons draws on the American, Soviet, Russian, South African, and Iraqi biological weapons programs to enhance our understanding of the special challenges posed by these weapons for arms control, deterrence, civilian-military relations, and intelligence. Koblentz also examines the aspirations of terrorist groups to develop these weapons and the obstacles they have faced. Biological weapons, Koblentz argues, will continue to threaten international security until defenses against such weapons are improved, governments can reliably detect biological weapon activities, the proliferation of materials and expertise is limited, and international norms against the possession and use of biological weapons are strengthened.

Author : Ken Alibek,Stephen Handelman
Publisher : Delta
Page : 338 pages
File Size : 42,5 Mb
Release : 2014-03-05
Category : History
ISBN : 9780804152655

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Biohazard by Ken Alibek,Stephen Handelman Pdf

“Read and be amazed. . . . An important and fascinating look into a terrifying world of which we were blissfully unaware.”—Robin Cook, author of Contagion Anthrax. Smallpox. Incurable and horrifying Ebola-related fevers. For two decades, while a fearful world prepared for nuclear winter, an elite team of Russian bioweaponeers began to till a new killing field: a bleak tract sown with powerful seeds of mass destruction—by doctors who had committed themselves to creating a biological Armageddon. Biohazard is the never-before-told story of Russia’s darkest, deadliest, and most closely guarded Cold War secret. No one knows more about Russia’s astounding experiments with biowarfare than Ken Alibek. Now the mastermind behind Russia’s germ warfare effort reveals two decades of shocking breakthroughs . . . how Moscow’s leading scientists actually reengineered hazardous microbes to make them even more virulent . . . the secrets behind the discovery of an invisible, untraceable new class of biological agents just right for use in political assassinations . . . the startling story behind Russia’s attempt to turn a sample of the AIDS virus into the ultimate bioweapon. And in a chilling work of real-world intrigue, Biohazard offers us all a rare glimpse into a shadowy scientific underworld where doctors manufacture mass destruction, where witnesses to errors are silenced forever, and where ground zero is closer than we ever dared believe. Praise for Biohazard “Harrowing . . . richly descriptive . . . [an] absorbing account.”—The New York Times Book Review “Remarkable . . . terrifying revelations . . . [Ken Alibek’s] overall message is ignored at great national peril.”—Newsday

Author : Katherine Paris
Publisher : Springer Nature
Page : 281 pages
File Size : 40,8 Mb
Release : 2022-12-15
Category : Science
ISBN : 9783031218200

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Genome Editing and Biological Weapons by Katherine Paris Pdf

This monograph introduces current genome editing technologies—clustered regularly interspaced short palindromic repeat (CRISPR)-CRISPR-associated (Cas) systems, transcription activator-like effector nucleases (TALENs), and zinc-finger nucleases (ZFNs)—and provides an assessment of the risk of misuse of these technologies based on the following parameters: accessibility, ease of misuse, magnitude of potential harm, and imminence of potential misuse. The findings from this assessment are applied to analyze and evaluate the threat posed by the intentional misuse of genome editing technologies to develop biological weapons. Furthermore, the book discusses the implications of misuse for different applications of genome editing, such as making existing pathogens more dangerous, modifying the human microbiome, weaponizing gene drives, engineering super soldiers, and augmenting the general population to confer economic advantages. Technologies that enable genome editing with programmable nucleases—including CRISPR, TALEN, and ZFN—allow for the precise genetic modification of organisms and cultured cells. While these technologies are used for a variety of beneficial applications, intelligence and defense experts have raised concerns that genome editing technologies, especially CRISPR, could be misused to develop new and improved biological weapons. Furthermore, experts worry that the number and type of actors who could potentially misuse genome editing is dramatically increasing given the democratization of biology, which is allowing biology to become more accessible to everyone including nonexperts. The book provides a comprehensive assessment of how feasible it is for users with different levels of knowledge and skill to acquire and then to apply the technologies to develop a biological weapon. It also provides an assessment of governability and a tailored set of recommendations that address security concerns. These recommendations are sensitive to the cost-benefit trade-off of regulating genome editing technologies. The book targets researchers as well as intelligence analysts, defense and security personnel, and policymakers.

Author : W. Seth Carus,National Defense University (U S ),National Defense University. Center for the Study of Weapons of Mass Destruction
Publisher : Government Printing Office
Page : 80 pages
File Size : 44,8 Mb
Release : 2017-08-03
Category : History
ISBN : 0160941482

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A Short History of Biological Warfare by W. Seth Carus,National Defense University (U S ),National Defense University. Center for the Study of Weapons of Mass Destruction Pdf

This publication gives a history of biological warfare (BW) from the prehistoric period through the present, with a section on the future of BW. The publication relies on works by historians who used primary sources dealing with BW. In-depth definitions of biological agents, biological weapons, and biological warfare (BW) are included, as well as an appendix of further reading on the subject. Related items: Arms & Weapons publications can be found here: https://bookstore.gpo.gov/catalog/arms-weapons Hazardous Materials (HAZMAT & CBRNE) publications can be found here: https://bookstore.gpo.gov/catalog/hazardous-materials-hazmat-cbrne

Author : Brecht Volders
Publisher : Routledge
Page : 205 pages
File Size : 48,6 Mb
Release : 2021-07-08
Category : Political Science
ISBN : 9781000408720

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The Nuclear Terrorism Threat by Brecht Volders Pdf

This book examines the threat of a terrorist organisation constructing and detonating a nuclear bomb. It explores the role and impact of the organisational design of a terrorist organisation in implementing a nuclear terrorism plot. In order to do so, the work builds on the organisational analogy between an assumed nuclear terrorism scenario and four case studies as follows: the construction of the first atomic bombs at Los Alamos; South Africa’s Peaceful Nuclear Explosives (PNE) program; Aum Shinrikyo’s chemical-biological armament activities; and Al Qaeda’s implementation of the 9/11 attacks. Extrapolating insights from these case studies, this book introduces the idea of an effectiveness-efficiency trade-off. On the one hand, it will be argued that a more organic organisational design is likely to benefit the effective implementation of a nuclear terrorism project. On the other hand, this type of organic organisational design is also likely to simultaneously constitute an inefficient way for a terrorist organisation to guarantee its operational and organisational security. It follows, then, that the implementation of a nuclear terrorism plot via an organic organisational design is also likely to be an inefficient strategy for a terrorist organisation to achieve its strategic and political goals. This idea of an effectiveness-efficiency trade-off provides us with a tool to strengthen the comprehensive nature of future nuclear terrorism threat assessments and sheds new light on the ongoing debates within the nuclear terrorism literature. This book will be of particular interest to students of nuclear proliferation, terrorism studies, international organisations, and security studies in general.

Author : Milton Leitenberg,Raymond A Zilinskas,Jens H Kuhn
Publisher : Harvard University Press
Page : 956 pages
File Size : 42,5 Mb
Release : 2012-06-29
Category : History
ISBN : 9780674065260

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The Soviet Biological Weapons Program by Milton Leitenberg,Raymond A Zilinskas,Jens H Kuhn Pdf

This is the first attempt to understand the full scope of the USSR’s offensive biological weapons research, from inception in the 1920s. Gorbachev tried to end the program, but the U.S. and U.K. never obtained clear evidence that he succeeded, raising the question whether the means for waging biological warfare could be present in Russia today.

Author : Susan Wright
Publisher : MIT Press (MA)
Page : 446 pages
File Size : 46,8 Mb
Release : 1990
Category : Biological warfare (International law)
ISBN : 0262231484

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Preventing a Biological Arms Race by Susan Wright Pdf

This timely sourcebook presents the essential technical, political, legal, and historical background needed for informed judgments about the recent expansion of military interest in the life sciences particularly in the weapons potential of the new biotechnology. Beyond providing a history and analysis of trends in these areas, "Preventing a Biological Arms Race also develops the case for strengthening national and international commitments to biological disarmament and proposes courses of action to achieve this goal. "In theory, " Susan Wright observes, "the menace of biological warfare should no longer be with us." Developing, producing, and stockpiling biological weapons are unconditionally banned by international treaty. EastWest military rivalry and confrontations in the Middle East have eroded confidence in the treaty regime, however. The advent of genetic engineering and other new biotechnologies has revived military interest in biological weaponry, generating concern about the potential weapons applications of biological research. The 15 contributions by experts from a wide range of disciplines include a history of U.S. biological warfare policy, analysis of the ethical issues posed by defensive biological warfare research, case studies of alleged violations of the international legal regime prohibiting biological weapons, reviews of that regime, and proposals for strengthening the barriers to biological warfare. A series of 14 appendices collect important data and documents related to biological weapons. Susan Wright is a historian of science at the Residential College of the University of Michigan where she directs the Science and Society Program. This book was prepared underthe sponsorship of the Council for Responsible Genetics.

Author : Anonim
Publisher : Unknown
Page : 152 pages
File Size : 55,8 Mb
Release : 2016
Category : Military art and science
ISBN : UCR:31210025140748

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Military Review by Anonim Pdf

Author : Anonim
Publisher : Unknown
Page : 152 pages
File Size : 49,5 Mb
Release : 2016-07
Category : Military art and science
ISBN : PURD:32754084040181

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Professional Journal of the United States Army by Anonim Pdf

Author : Lijun Shang,Malcolm Dando,Michael Crowley
Publisher : Royal Society of Chemistry
Page : 672 pages
File Size : 55,6 Mb
Release : 2018-08-20
Category : Medical
ISBN : 9781782626497

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Preventing Chemical Weapons by Lijun Shang,Malcolm Dando,Michael Crowley Pdf

The life and chemical sciences are in the midst of a period of rapid and revolutionary transformation that will undoubtedly bring societal benefits but also have potentially malign applications, notably in the development of chemical weapons. Such concerns are exacerbated by the unstable international security environment and the changing nature of armed conflict, which could fuel a desire by certain States to retain and use existing chemical weapons, as well as increase State interest in creating new weapons; whilst a broader range of actors may seek to employ diverse toxic chemicals as improvised weapons. Stark indications of the multi-faceted dangers we face can be seen in the chemical weapons attacks against civilians and combatants in Iraq and Syria, and also in more targeted chemical assassination operations in Malaysia and the UK. Using a multi-disciplinary approach, and drawing upon an international group of experts, this book analyses current and likely near-future advances in relevant science and technology, assessing the risks of their misuse. The book examines the current capabilities, limitations and failures of the existing international arms control and disarmament architecture – notably the Chemical Weapons Convention – in preventing the development and use of chemical weapons. Through the employment of a novel Holistic Arms Control methodology, the authors also look beyond the bounds of such treaties, to explore the full range of international law, international agreements and regulatory mechanisms potentially applicable to weapons employing toxic chemical agents, in order to develop recommendations for more effective routes to combat their proliferation and misuse. A particular emphasis is given to the roles that chemical and life scientists, health professionals and wider informed activist civil society can play in protecting the prohibition against poison and chemical weapons; and in working with States to build effective and responsive measures to ensure that the rapid scientific and technological advances are safeguarded from hostile use and are instead employed for the benefit of us all.

Author : Organisation mondiale de la santé,World Health Organization,Julian Perry Robinson,WHO,World Health Organization Staff
Publisher : World Health Organization
Page : 365 pages
File Size : 44,7 Mb
Release : 2004-01-21
Category : Architecture
ISBN : 9789241546157

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Public Health Response to Biological and Chemical Weapons by Organisation mondiale de la santé,World Health Organization,Julian Perry Robinson,WHO,World Health Organization Staff Pdf

This is the second edition of this publication which focuses on the public health aspects of the possible deliberate use of biological or chemical agents. Issues discussed include: the key principles for public health planning, risk assessment, hazard identification and evaluation, risk management strategies, and response planning as part of existing national emergency plans, disease surveillance and early warning systems, the national and international legal framework, and international sources of assistance. Technical annexes cover a range of issues including chemical agents, toxins, biological agents, principles of protection, precautions against the sabotage of drinking water, food and other products, information resources and the affiliation of WHO Member States to the international treaties on biological and chemical weapons.

Author : Matthew Cobb
Publisher : Profile Books
Page : 403 pages
File Size : 47,8 Mb
Release : 2022-09-01
Category : Medical
ISBN : 9781782838036

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The Genetic Age by Matthew Cobb Pdf

A TIMES ENVIRONMENT AND SCIENCE BOOK OF THE YEAR 2022 'The ideal guide to what is not just a fiendishly complex area of science but also an ethical minefield' Mail on Sunday A new gene editing technology, invented just seven years ago, has turned humanity into gods. Enabling us to manipulate the genes in virtually any organism with exquisite precision, CRISPR has given scientists a degree of control that was undreamt of even in science fiction. But CRISPR is just the latest, giant leap in a long journey to master genetics. The Genetic Age shows the astonishing, world-changing potential of the new genetics and the possible threats it poses, sifting between fantasy and the reality when it comes to both benefits and dangers. By placing each phase of discovery, anticipation and fear in the context of over fifty years of attempts to master the natural world, Matthew Cobb, the Baillie-Gifford-shortlisted author of The Idea of the Brain, weaves the stories of science, history and culture to shed new light on our future. With the powers now at our disposal, it is a future that is almost impossible to imagine - but it is one we will create ourselves.

Author : National Defense University
Publisher : NDU Press
Page : 356 pages
File Size : 49,8 Mb
Release : 2010-10
Category : History
ISBN : 9781780390406

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Bio-Inspired Innovation and National Security by National Defense University Pdf

Despite the vital importance of the emerging area of biotechnology and its role in defense planning and policymaking, no definitive book has been written on the topic for the defense policymaker, the military student, and the private-sector bioscientist interested in the "emerging opportunities market" of national security. This edited volume is intended to help close this gap and provide the necessary backdrop for thinking strategically about biology in defense planning and policymaking. This volume is about applications of the biological sciences, here called "biologically inspired innovations," to the military. Rather than treating biology as a series of threats to be dealt with, such innovations generally approach the biological sciences as a set of opportunities for the military to gain strategic advantage over adversaries. These opportunities range from looking at everything from genes to brains, from enhancing human performance to creating renewable energy, from sensing the environment around us to harnessing its power.