Behavioral Genetics Of The Mouse

Author : Wim E. Crusio,Frans Sluyter,Robert T. Gerlai,Susanna Pietropaolo
Publisher : Cambridge University Press
Page : 361 pages
File Size : 47,7 Mb
Release : 2013-04-25
Category : Science
ISBN : 9781107355576

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Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by Wim E. Crusio,Frans Sluyter,Robert T. Gerlai,Susanna Pietropaolo Pdf

The first volume in the new Cambridge Handbooks in Behavioral Genetics series, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically modified or pharmacologically treated animals and in the interpretation and analyses of the results obtained. The book offers a comprehensive overview of the genetics of naturally occurring variation in mouse behavior, from perception and spontaneous behaviors such as exploration, aggression, social interactions and motor behaviors, to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike.

Author : Wim E. Crusio,Frans Sluyter,Robert T. Gerlai,Susanna Pietropaolo
Publisher : Cambridge University Press
Page : 361 pages
File Size : 50,9 Mb
Release : 2013-04-25
Category : Medical
ISBN : 9781107034815

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Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by Wim E. Crusio,Frans Sluyter,Robert T. Gerlai,Susanna Pietropaolo Pdf

A comprehensive review of the current state of our knowledge on the inheritance of normal behaviour in the laboratory mouse.

Author : Gardner Lindzey,Delbert D. Thiessen
Publisher : Ardent Media
Page : 362 pages
File Size : 44,9 Mb
Release : 1970
Category : Science
ISBN : 0390562750

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Contributions to Behavior-genetic Analysis by Gardner Lindzey,Delbert D. Thiessen Pdf

Author : W. E. Crusio
Publisher : Unknown
Page : 362 pages
File Size : 55,8 Mb
Release : 2014-05-14
Category : Nature
ISBN : 1107342201

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Behavioral Genetics of the Mouse: Volume 1, Genetics of Behavioral Phenotypes by W. E. Crusio Pdf

"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--

Author : Wim E. Crusio
Publisher : Unknown
Page : 362 pages
File Size : 49,7 Mb
Release : 2013
Category : Electronic
ISBN : 1107345952

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Behavioral Genetics of the Mouse by Wim E. Crusio Pdf

A comprehensive review of the current state of our knowledge on the inheritance of normal behaviour in the laboratory mouse.

Author : Susanna Pietropaolo,Frans Sluyter,W. E. Crusio
Publisher : Unknown
Page : 472 pages
File Size : 41,7 Mb
Release : 2014-10-03
Category : NATURE
ISBN : 1316073211

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Behavioral Genetics of the Mouse: Volume 2, Genetic Mouse Models of Neurobehavioral Disorders by Susanna Pietropaolo,Frans Sluyter,W. E. Crusio Pdf

A comprehensive and critical overview of the major genetically modified mouse lines used to model human neurobehavioral disorders.

Author : W. E. Crusio,Frans Sluyter,R. T. Gerlai,Susanna Pietropaolo
Publisher : Unknown
Page : 0 pages
File Size : 42,8 Mb
Release : 2013
Category : Behavior genetics
ISBN : LCCN:2012030953

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Behavioral Genetics of the Mouse: Genetic mouse models of neurobehavioral disorders by W. E. Crusio,Frans Sluyter,R. T. Gerlai,Susanna Pietropaolo Pdf

"The first volume in the new Cambridge Handbooks in Behavioral Genetics, Behavioral Genetics of the Mouse provides baseline information on normal behaviors, essential in both the design of experiments using genetically-modified or pharmacologically-treated animals, and in the interpretation and analyses of the results obtained. Offering a comprehensive overview of the genetics of naturally-occurring variation in mouse behavior; from perception and spontaneous behaviors, such as exploration, aggression, social interactions and motor behaviors to reinforced behaviors such as the different types of learning. Also included are numerous examples of potential experimental problems, which will aid and guide researchers trying to troubleshoot their own studies. A lasting reference, the thorough and comprehensive reviews offer an easy entrance into the extensive literature in this field, and will prove invaluable to students and specialists alike"--

Author : Wim E. Crusio,Frans Sluyter,Susanna Pietropaolo,R. T. Gerlai
Publisher : Cambridge University Press
Page : 471 pages
File Size : 46,6 Mb
Release : 2014-09-25
Category : Psychology
ISBN : 9781107044456

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Behavioral Genetics of the Mouse by Wim E. Crusio,Frans Sluyter,Susanna Pietropaolo,R. T. Gerlai Pdf

A comprehensive and critical overview of the major genetically modified mouse lines used to model human neurobehavioral disorders.

Author : Robert Plomin
Publisher : Macmillan
Page : 568 pages
File Size : 46,7 Mb
Release : 2008-02-22
Category : Psychology
ISBN : UOM:39015073625942

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Behavioral Genetics by Robert Plomin Pdf

This book provides an overview of human and animal behavioral genetics and examines the crossroads where the fields of psychology, psychiatry, and genetics intersect.

Author : Douglas Wahlsten
Publisher : Academic Press
Page : 304 pages
File Size : 45,6 Mb
Release : 2010-11-25
Category : Nature
ISBN : 0123756758

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Mouse Behavioral Testing by Douglas Wahlsten Pdf

Mouse Behavioral Testing: How to Use Mice in Behavioral Neuroscience provides detailed explanations of how to conduct an experiment on mouse behavior from the initial planning of the research design through every step of the process until the data analysis phase. The book discusses the practical matters that need to be considered carefully when working with any species of animal, such as how many animals need to be tested. It describes the tests and techniques devised specifically for work with mice. Every step of the research process is illustrated with real situations encountered in previous studies. All examples are based on real experiments, and extensive details of several published experiments are provided. The essential features of a behavioral test protocol are outlined, and several complete protocols are provided. Methods to balance the order of tests and determine throughput are described, then a completely balanced order of tests in a complex experiment is presented. The book will be useful for those already familiar with the general principles of research but are new to the realm of behavioral testing of live mice. It will also serve as a text for a formal course, most likely at the graduate level. A guide to running a behavioral testing lab, including the many aspects of mouse research beyond the confines of the specific test Diagrams and photographs are shown for many kinds of apparatus and test situations with sufficient details such as dimensions to enable building of replicas Provides step-by-step instructions on planning and executing behavioral experiments in order to run them successfully

Author : Nicole C. Nelson
Publisher : University of Chicago Press
Page : 262 pages
File Size : 46,7 Mb
Release : 2018-04-04
Category : Science
ISBN : 9780226546117

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Model Behavior by Nicole C. Nelson Pdf

Mice are used as model organisms across a wide range of fields in science today—but it is far from obvious how studying a mouse in a maze can help us understand human problems like alcoholism or anxiety. How do scientists convince funders, fellow scientists, the general public, and even themselves that animal experiments are a good way of producing knowledge about the genetics of human behavior? In Model Behavior, Nicole C. Nelson takes us inside an animal behavior genetics laboratory to examine how scientists create and manage the foundational knowledge of their field. Behavior genetics is a particularly challenging field for making a clear-cut case that mouse experiments work, because researchers believe that both the phenomena they are studying and the animal models they are using are complex. These assumptions of complexity change the nature of what laboratory work produces. Whereas historical and ethnographic studies traditionally portray the laboratory as a place where scientists control, simplify, and stabilize nature in the service of producing durable facts, the laboratory that emerges from Nelson’s extensive interviews and fieldwork is a place where stable findings are always just out of reach. The ongoing work of managing precarious experimental systems means that researchers learn as much—if not more—about the impact of the environment on behavior as they do about genetics. Model Behavior offers a compelling portrait of life in a twenty-first-century laboratory, where partial, provisional answers to complex scientific questions are increasingly the norm.

Author : Robert R.H. Anholt,Trudy F. C. Mackay
Publisher : Academic Press
Page : 345 pages
File Size : 44,9 Mb
Release : 2009-09-21
Category : Psychology
ISBN : 9780080919898

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Principles of Behavioral Genetics by Robert R.H. Anholt,Trudy F. C. Mackay Pdf

Principles of Behavioral Genetics provides an introduction to the fascinating science that aims to understand how our genes determine what makes us tick. It presents a comprehensive overview of the relationship between genes, brain, and behavior. Introductory chapters give clear explanations of basic processes of the nervous system and fundamental principles of genetics of complex traits without excessive statistical jargon. Individual chapters describe the genetics of social interactions, olfaction and taste, memory and learning, circadian behavior, locomotion, sleep, and addiction, as well as the evolution of behavior. Whereas the focus is on genetics, neurobiological and ecological aspects are also included to provide intellectual breadth. The book uses examples that span the gamut from classical model organisms to non-model systems and human biology, and include both laboratory and field studies. Samples of historical information accentuate the text to provide the reader with an appreciation of the history of the field. This book will be a valuable resource for future generations of scientists who focus on the field of behavioral genetics. Defines the emerging science of behavioral genetics Engagingly written by two leading experts in behavioral genetics Clear explanations of basic quantitative genetic, neurogenetic and genomic applications to the study of behavior Numerous examples ranging from model organisms to non-model systems and humans Concise overviews and summaries for each chapter

Author : G. Lindzey
Publisher : Unknown
Page : 336 pages
File Size : 42,6 Mb
Release : 1970
Category : Electronic
ISBN : OCLC:925779465

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Contributions to Behavior-genetic Analysis by G. Lindzey Pdf

Author : National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,International Workshop on the Development of Science-based Guidelines for Laboratory Animal Care Program Committee
Publisher : National Academies Press
Page : 262 pages
File Size : 49,6 Mb
Release : 2004-10-21
Category : Science
ISBN : 9780309165549

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The Development of Science-based Guidelines for Laboratory Animal Care by National Research Council,Division on Earth and Life Studies,Institute for Laboratory Animal Research,International Workshop on the Development of Science-based Guidelines for Laboratory Animal Care Program Committee Pdf

The Development of Science-based Guidelines for Laboratory Animal Care is the summary of an international workshop held in Washington, DC, in November 2003 to bring together experts from around the world to discuss the available knowledge that can positively influence current and pending guidelines for laboratory animal care, identify gaps in that knowledge in order to encourage future research endeavors, and discuss the scientific evidence that can be used to assess the benefits and costs of various regulatory approaches affecting facilities, research, and animal welfare.

Author : Jonathan C. Gewirtz,Yong-Kyu Kim
Publisher : Springer
Page : 389 pages
File Size : 41,5 Mb
Release : 2016-08-10
Category : Medical
ISBN : 9781493937776

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Animal Models of Behavior Genetics by Jonathan C. Gewirtz,Yong-Kyu Kim Pdf

This stimulating analysis reviews the broad potential of animal models to foster a deeper understanding of human pathology, strengthen connections between genetic and behavioral studies, and develop more effective treatments for mental disorders. Widely-studied and lesser-used species are examined in models that capture features along the continuum of normative and pathological behavior. The models highlight genetic causes of core features, or endophenotypes, of developmental, internalizing, and externalizing disorders, as well as dementia. Expert contributors address questions ranging from how suitable species are chosen for study to the costs and benefits of using inbred versus outbred strains, and the effects of housing environment on subject animals. Larger issues addressed include how to evaluate the applicability of animal behavioral models to the human condition and how these models can harness emerging molecular technologies to further our understanding of the genetic basis of mental illness. Included in the coverage: Mating and fighting in Drosophila. Attachment and social bonding. Impulsivity in rodents and humans. Animal models of cognitive decline. Animal models of social cognition. Future directions for animal models in behavioral genetics. A detailed map of where this evolving field is headed, Animal Models of Behavior Genetics shows geneticists, molecular biologists, and cognitive neuroscientists paths beyond established concepts toward a more knowledgeable and collaborative future.