Bile Acids And Pregnancy

Author : U. Leuschner,P.A. Berg,J. Holtmeier
Publisher : Springer Science & Business Media
Page : 106 pages
File Size : 54,5 Mb
Release : 2002-12-31
Category : Medical
ISBN : 0792387821

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Bile Acids and Pregnancy by U. Leuschner,P.A. Berg,J. Holtmeier Pdf

Pregnancy represents an allograft in so far that half of the antigens are foreign to the mother. Therefore, a bidirectional interaction between the maternal and the fetal immune systems must exist, which could be disturbed by preexisting autoimmune liver diseases. Since nowadays autoimmune liver diseases are increasingly detected as early stage diseases due to modern diagnostic procedures, e.g. in women of childbearing age, and since the number of posttransplant pregnancies has become an issue due to improved survival, questions concerning regnancy, autoimmune liver disease and treatment options with bile acids and/or immunosuppressants are of an ever-increasing interest. This book, the proceedings of a Falk Workshop held in Freiburg, Germany, on June 2, 2002, is certainly unable to give any definite answers to any of the hundreds of still remaining questions in this fascinating field, but hopefully it will help to stimulate and initiate cooperation among immunologists, bile acid researchers, gynaecologists and internists.

Author : Roshan Fernando,Pervez Sultan,Sioned Phillips
Publisher : Springer Nature
Page : 500 pages
File Size : 45,5 Mb
Release : 2022-02-07
Category : Medical
ISBN : 9783030724870

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Quick Hits in Obstetric Anesthesia by Roshan Fernando,Pervez Sultan,Sioned Phillips Pdf

This book provides easy to follow guidance on how to manage emergency situations and common problems in obstetric anesthesia. The book provides different anesthetic recipes for obstetric procedures and describes challenges that will be encountered on a day-to-day basis. There are trouble-shooting chapters and ‘what to do lists’ for frequent dilemmas. The book covers obstetric-specific resuscitation and medical emergencies seen on the labor ward. Antenatal and postpartum complications relating to anesthesia are covered as well as issues that may arise during follow up of patients who have had neuraxial anesthesia during delivery. Quick Hits in Obstetric Anesthesia should be used as a cognitive aid for emergency cases and as a decision-making tool for urgent management plans. It is a guide to common problems and provides core knowledge to facilitate anesthesia care on labor wards for all grades of anesthetist.

Author : Jorma Heikkinen
Publisher : Unknown
Page : 41 pages
File Size : 44,6 Mb
Release : 1982
Category : Electronic
ISBN : 9514213432

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Bile Acids in Pregnancy by Jorma Heikkinen Pdf

Author : Anonim
Publisher : Unknown
Page : 0 pages
File Size : 54,5 Mb
Release : 2016
Category : Electronic
ISBN : 8131247058

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OBSTETRICS by Anonim Pdf

Author : E. Carstens,Tasuku Akiyama
Publisher : CRC Press
Page : 482 pages
File Size : 52,5 Mb
Release : 2014-02-25
Category : Science
ISBN : 9781466505438

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Itch by E. Carstens,Tasuku Akiyama Pdf

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Author : Anonim
Publisher : Unknown
Page : 2 pages
File Size : 46,8 Mb
Release : 1984
Category : Coronary heart disease
ISBN : MINN:20000004252553

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Coronary Primary Prevention Trial by Anonim Pdf

Author : Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff
Publisher : John Wiley & Sons
Page : 1156 pages
File Size : 54,7 Mb
Release : 2020-03-09
Category : Medical
ISBN : 9781119436829

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The Liver by Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff Pdf

Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Author : Catherine Nelson-Piercy,Joanna Girling
Publisher : Springer Science & Business Media
Page : 195 pages
File Size : 46,6 Mb
Release : 2007-05-26
Category : Medical
ISBN : 9781846285820

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Obstetric Medicine by Catherine Nelson-Piercy,Joanna Girling Pdf

Recognition of the importance of maternal medicine is now reflected in the content of the MRCOG exam, core training and higher training in both obstetrics and medicine. This book approaches obstetric medicine from the point of view of real patients and clinical scenarios as well as model answers to exam questions. The book will be invaluable for trainees and consultants who want to ‘test themselves’.

Author : Lajos Okolicsanyi,Geza Csomos,Gaetano Crepaldi
Publisher : Springer Science & Business Media
Page : 435 pages
File Size : 43,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642726316

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Assessment and Management of Hepatobiliary Disease by Lajos Okolicsanyi,Geza Csomos,Gaetano Crepaldi Pdf

The contributions to this volume cover all aspects of the assessment and management of hepatobiliary disease. The focal points of the book consist of three state-of-the-art summaries. The first of these deals with the highly topical problem of liver transplants from the point of view of patient selection. The second considers drug-induced liver injury in view of the fact that the liver is the main metabolic site for a number of drugs. The final summary deals with liver and aging: it asks whether the liver follows the aging process of the host organisms and whether the liver of aged liver transplant candidate donors could be suitable for grafting. Aside from these topics, the volume presents basic research on hepatic transport mechanisms, intrahepatic cholestasis and gall-stone disease, which serves as a background for the topics more specifically concerning the assessment of liver function. Much of the book is then devoted to the management of the commonest forms of liver diseases and their complications, such as chronic active hepatitis, liver cirrhosis, portal hypertension, hepatic encephalopathy, hepatorenal syndrome, and ascites.

Author : Elizabeth J. Carey,Keith D. Lindor
Publisher : Springer
Page : 265 pages
File Size : 47,6 Mb
Release : 2014-07-18
Category : Medical
ISBN : 9781493910137

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Cholestatic Liver Disease by Elizabeth J. Carey,Keith D. Lindor Pdf

Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.

Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Publisher : Cambridge University Press
Page : 995 pages
File Size : 48,7 Mb
Release : 2007-05-07
Category : Medical
ISBN : 9781139464031

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Liver Disease in Children by Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Pdf

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Author : Albert P. Li
Publisher : John Wiley & Sons
Page : 530 pages
File Size : 47,7 Mb
Release : 2021-07-27
Category : Medical
ISBN : 9781119170846

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Transporters and Drug-Metabolizing Enzymes in Drug Toxicity by Albert P. Li Pdf

TRANSPORTERS AND DRUG-METABOLIZING ENZYMES IN DRUG TOXICITY Explore up-to-date coverage on the interaction between drug metabolism enzymes, transporters, and drug toxicity with this leading resources Transporters and Drug-Metabolizing Enzymes in Drug Toxicity delivers a comprehensive and updated review of the relationship between drug metabolism, transporters, and toxicity, providing insights into a major challenge in drug development – accurate assessment of human drug toxicity. Combining two disciplines frequently considered independently of one another, the book combines drug metabolism and toxicology with a focus on the role of biotransformation on drug toxicity and as a major factor for species and individual differences. Mechanism and species differences in drug metabolizing enzymes and transporters are discussed, as are the methods used to investigate the role of drug metabolizing enzymes and transporters in drug toxicity. Finally, the distinguished authors describe promising new experimental approaches to accurately assessing human drug toxicity via the consideration of human-specific drug metabolism in toxicity assays. In addition to topics as diverse as extended clearance models, experimental approaches for the estimation of DILI potential of drug candidates and roles of transporters in renal drug toxicity, readers will also enjoy the inclusion of such subjects as: A thorough overview of and introduction to drug metabolism and transporters and drug toxicity An exploration of drug metabolism enzymes and transporter activities as risk factors of marketed drugs associated with drug-induced fatalities A discussion of human-based in vitro experimental models for the evaluation of metabolism-dependent drug toxicity A treatment of mechanism-based experimental models for the evaluation of BSEP inhibition and DILI An examination of transporters and cochlea toxicity Perfect for scientists, students, and practitioners with interests in metabolism, toxicology, and drug development in the pharmaceutical industry, Transporters and Drug-Metabolizing Enzymes in Drug Toxicity will also earn a place in the libraries of medicinal chemists, pharmacologists, biochemists, toxicologists, and regulators in the pharmaceutical and health industries.

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 52,9 Mb
Release : 1999
Category : Medical
ISBN : 0781719526

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Hepatotoxicity by Hyman J. Zimmerman Pdf

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Author : Jose Manuel Miranda Lopez,Alberto Cepeda Saez
Publisher : Royal Society of Chemistry
Page : 383 pages
File Size : 49,8 Mb
Release : 2021-12-17
Category : Medical
ISBN : 9781788018852

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Fats and Associated Compounds by Jose Manuel Miranda Lopez,Alberto Cepeda Saez Pdf

Through this book, the Editors have compiled the most up to date and well-documented information on many aspects of the development and application of novel dietary patterns related to fatty compounds, with special emphasis on beneficial effects.

Author : Adel Elkady,Prabha Sinha,Soad Ali Zaki Hassan
Publisher : Cambridge University Press
Page : 215 pages
File Size : 45,9 Mb
Release : 2019-10-24
Category : Medical
ISBN : 9781108716635

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Infections in Pregnancy by Adel Elkady,Prabha Sinha,Soad Ali Zaki Hassan Pdf

Provides effective diagnosis and management of infectious diseases in pregnant women in a single comprehensive available resource for busy clinicians.