Cholestatic Liver Disease

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Cholestatic Liver Disease

Elizabeth J. Carey,Keith D. Lindor
Cholestatic Liver Disease Book PDF

Author : Elizabeth J. Carey,Keith D. Lindor
Publisher : Springer
Page : 265 pages
File Size : 43,6 Mb
Release : 2014-07-18
Category : Medical
ISBN : 9781493910137

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Cholestatic Liver Disease by Elizabeth J. Carey,Keith D. Lindor Pdf

Since the publication of the first edition, there have been advances in both the diagnosis and the management of many of the cholestatic liver diseases. Cholestatic Liver Disease, Second Edition thoroughly updates the topics previously addressed, such as primary biliary cirrhosis, primary sclerosing cholangitis and cholestatic variants of drug hepatotoxicity and viral disease. New treatments, such as the development of the farnesoid X receptor agonists for the treatment of PBC, are highlighted. Current guidelines and areas of uncertainty are also covered. Additionally, new chapters have been added to reflect the changing landscape of cholestatic liver disease. Cholestatic Liver Disease, Second Edition is a concise yet comprehensive summary of the current status of the field and is of value to clinicians and researchers interested in patients with cholestatic liver disease provide that will help to guide patient management and stimulate investigative efforts.

Drug-Induced Liver Injury

Anonim
Drug Induced Liver Injury Book PDF

Author : Anonim
Publisher : Academic Press
Page : 288 pages
File Size : 49,5 Mb
Release : 2019-07-13
Category : Medical
ISBN : 9780128173176

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Drug-Induced Liver Injury by Anonim Pdf

Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Itch

E. Carstens,Tasuku Akiyama
Itch Book PDF

Author : E. Carstens,Tasuku Akiyama
Publisher : CRC Press
Page : 482 pages
File Size : 40,6 Mb
Release : 2014-02-25
Category : Science
ISBN : 9781466505438

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Itch by E. Carstens,Tasuku Akiyama Pdf

Advances in itch research have elucidated differences between itch and pain but have also blurred the distinction between them. There is a long debate about how somatic sensations including touch, pain, itch, and temperature sensitivity are encoded by the nervous system. Research suggests that each sensory modality is processed along a fixed, direct-line communication system from the skin to the brain. Itch: Mechanisms and Treatment presents a timely update on all aspects of itch research and the clinical treatment of itch that accompanies many dermatological conditions including psoriasis, neuropathic itch, cutaneous t-cells lymphomas, and systemic diseases such as kidney and liver disease and cancer. Composed of contributions from distinguished researchers around the world, the book explores topics such as: Neuropathic itch Peripheral neuronal mechanism of itch The role of PAR-2 in neuroimmune communication and itch Mrgprs as itch receptors The role of interleukin-31 and oncostatin M in itch and neuroimmune communication Spinal coding of itch and pain Spinal microcircuits and the regulation of itch Examining new findings on cellular and molecular mechanisms, the book is a compendium of the most current research on itch, its prevalence in society, and the problems associated with treatment.

Liver Disease in Children

Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Liver Disease in Children Book PDF

Author : Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri
Publisher : Cambridge University Press
Page : 995 pages
File Size : 55,7 Mb
Release : 2007-05-07
Category : Medical
ISBN : 9781139464031

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Liver Disease in Children by Frederick J. Suchy,Ronald J. Sokol,William F. Balistreri Pdf

Completely revised new edition of the premier reference on pediatric liver disease. Liver Disease in Children, 3rd Edition provides authoritative coverage of every aspect of liver disease affecting infants, children, and adolescents. The book offers an integrated approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. Chapters are written by international experts and address the unique pathophysiology, manifestations, and management of these disorders in the pediatric population. The third edition has been thoroughly updated and features new contributions on liver development, cholestatic and autoimmune disorders, fatty liver disease, and inborn errors of metabolism. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Cholestatic Liver Disease

Keith D. Lindor,Jayant A. Talwalkar
Cholestatic Liver Disease Book PDF

Author : Keith D. Lindor,Jayant A. Talwalkar
Publisher : Springer Science & Business Media
Page : 191 pages
File Size : 47,9 Mb
Release : 2010-01-08
Category : Medical
ISBN : 9781597451185

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Cholestatic Liver Disease by Keith D. Lindor,Jayant A. Talwalkar Pdf

Over the past two decades, there has been a steady increase in knowledge associated with the clinical manifestations of cholestatic liver disease. Based on these clinical situations, this book provides useful and timely information on the ever-expanding subject of cholestatic liver disease. It supplies scientific updates from leading experts which relate to the clinical evaluation and management of cholestatic liver disorders.

Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease,

Cynthia Levy
Advances in Cholestatic Liver Diseases An issue of Clinics in Liver Disease Book PDF

Author : Cynthia Levy
Publisher : Elsevier Health Sciences
Page : 128 pages
File Size : 44,7 Mb
Release : 2016-01-07
Category : Medical
ISBN : 9780323429924

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Advances in Cholestatic Liver Diseases, An issue of Clinics in Liver Disease, by Cynthia Levy Pdf

Dr. Levy has secured the field’s top experts to offer the latest clinical reviews on cholestatic liver disease. The issue will include articles devoted to The Gut-Liver Axis; Update on Genetics in Primary Biliary Cirrhosis and Primary Sclerosing Cholangitis; New thoughts on IgG4 Associated Cholangitis; Cancer Risk and Surveillance in PSC; Novel Therapies for PBC; and Liver transplantation for Cholestatic Liver Diseases, to name a few. Dr. Levy’s issue will be the most current authority on cholestatic liver disease.

The Liver

Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff
The Liver Book PDF

Author : Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff
Publisher : John Wiley & Sons
Page : 1156 pages
File Size : 44,7 Mb
Release : 2020-03-09
Category : Medical
ISBN : 9781119436829

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The Liver by Irwin M. Arias,Harvey J. Alter,James L. Boyer,David E. Cohen,David A. Shafritz,Snorri S. Thorgeirsson,Allan W. Wolkoff Pdf

Bridging the gap between basic scientific advances and the understanding of liver disease — the extensively revised new edition of the premier text in the field. The latest edition of The Liver: Biology and Pathobiology remains a definitive volume in the field of hepatology, relating advances in biomedical sciences and engineering to understanding of liver structure, function, and disease pathology and treatment. Contributions from leading researchers examine the cell biology of the liver, the pathobiology of liver disease, the liver’s growth, regeneration, metabolic functions, and more. Now in its sixth edition, this classic text has been exhaustively revised to reflect new discoveries in biology and their influence on diagnosing, managing, and preventing liver disease. Seventy new chapters — including substantial original sections on liver cancer and groundbreaking advances that will have significant impact on hepatology — provide comprehensive, fully up-to-date coverage of both the current state and future direction of hepatology. Topics include liver RNA structure and function, gene editing, single-cell and single-molecule genomic analyses, the molecular biology of hepatitis, drug interactions and engineered drug design, and liver disease mechanisms and therapies. Edited by globally-recognized experts in the field, this authoritative volume: Relates molecular physiology to understanding disease pathology and treatment Links the science and pathology of the liver to practical clinical applications Features 16 new “Horizons” chapters that explore new and emerging science and technology Includes plentiful full-color illustrations and figures The Liver: Biology and Pathobiology, Sixth Edition is an indispensable resource for practicing and trainee hepatologists, gastroenterologists, hepatobiliary and liver transplant surgeons, and researchers and scientists in areas including hepatology, cell and molecular biology, virology, and drug metabolism.

Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease,

Cynthia Levy
Cholestatic Liver Diseases An Issue of Clinics in Liver Disease Book PDF

Author : Cynthia Levy
Publisher : Elsevier Health Sciences
Page : 244 pages
File Size : 49,7 Mb
Release : 2013-04-11
Category : Medical
ISBN : 9781455771998

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Cholestatic Liver Diseases, An Issue of Clinics in Liver Disease, by Cynthia Levy Pdf

Dr. Levy is a key leader in the field of hepatology , and she has enlisted authors who are top experts in their fields to submit state-of-the-art clinical reviews on cholestatic liver diseases. Articles are devoted to genetic determinants of cholestasis, nuclear receptors as drug targets, drug-induced cholestasis, primary sclerosing cholangitis, therapeutic advances in primary biliary cirrhosis, overlap syndromes, autoimmune sclerosing cholangitis, secondary sclerosing cholangitis, Focus is also on familial cholestasis, allagile syndrome and other hereditary causes of cholestasis, Systemic causes of cholestasis, advances in pathogenesis and treatment of pruritus, care of the cholestatic patient, and transplantation for cholestatic diseases . Readers will come away with a full overview of the diagnosis and treatment of cholestatic liver diseases.

Cholestatic Liver Diseases: Therapeutic Options and Perspectives

U. Leuschner,U. Broomé,A. Stiehl
Cholestatic Liver Diseases Therapeutic Options and Perspectives Book PDF

Author : U. Leuschner,U. Broomé,A. Stiehl
Publisher : Springer Science & Business Media
Page : 424 pages
File Size : 53,7 Mb
Release : 2004-06-30
Category : Medical
ISBN : 0792387937

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Cholestatic Liver Diseases: Therapeutic Options and Perspectives by U. Leuschner,U. Broomé,A. Stiehl Pdf

During the last decade, knowledge about cholestatic liver disease and concomitant diseases, such as ulcerative colitis, cholangio- and hepatocellular carcinoma, pancreas and colon cancer, has increased considerably. Studies on ursodeoxycholic acid treatment alone or in combination with immunosuppressive compounds and their positive effects on biliary liver disease as well as on so-called overlap syndromes or intestinal tumors are published in increasing numbers, and stimulate discussion on whether or not ursodeoxycholic acid is able to improve the general condition and/or life expectancy of patients. On the other hand, genetics, aetiological and pathogenetic aspects are still difficult to comprehend, but are the absolute prerequisite for the development of better treatment options. This book is the proceedings of Falk Symposium No. 136 (Part I of the XII Falk Liver Week, held in Freiburg, Germany, on October 15-16, 2003), and contains stimulating, exciting and controversial papers on clinical and also basic research at the highest scientific level.

Cholestatic Liver Diseases in Children and Adults

C.E. Broelsch,M. Burdelski,X. Rogiers
Cholestatic Liver Diseases in Children and Adults Book PDF

Author : C.E. Broelsch,M. Burdelski,X. Rogiers
Publisher : Springer
Page : 136 pages
File Size : 55,5 Mb
Release : 1997-03-31
Category : Medical
ISBN : UOM:39015041233423

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Cholestatic Liver Diseases in Children and Adults by C.E. Broelsch,M. Burdelski,X. Rogiers Pdf

Cholestatic disorders of infancy and adulthood represent a major group of causes of end-stage chronic liver disease. There has been great scientific interest in these disorders in recent years, so the time has come to evaluate treatment modalities in old and even new cholestatic diseases. Since secondary malnutrition plays an important role in inducing multiorgan morbidity in these patients, nutritional and metabolic aspects need better understanding. The influence of disease and nutrition-related problems on liver transplantation as the ultimate therapy of cholestatic disorders is also of current interest. This book, the proceedings of an International Falk Workshop held in Hamburg, Germany, 25-26 January 1996, brings together a group of experts from around the world to explore and elucidate these topics. It will be of interest to all hepatologists and clinicians, especially paediatricians.

ECAB Cholestatic Liver Disease - E-Book

Prabha Sawant
ECAB Cholestatic Liver Disease E Book Book PDF

Author : Prabha Sawant
Publisher : Elsevier Health Sciences
Page : 154 pages
File Size : 53,7 Mb
Release : 2014-12-11
Category : Medical
ISBN : 9788131239636

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ECAB Cholestatic Liver Disease - E-Book by Prabha Sawant Pdf

ECAB Cholestatic Liver Disease - E-Book

Cholestatic Liver Diseases

M.P. Manns
Cholestatic Liver Diseases Book PDF

Author : M.P. Manns
Publisher : Springer
Page : 318 pages
File Size : 52,6 Mb
Release : 1998-08-31
Category : Medical
ISBN : UOM:39015043822892

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Cholestatic Liver Diseases by M.P. Manns Pdf

Many liver diseases may be associated with cholestasis, and in some of them cholestasis is the leading symptom. This book, the proceedings of Falk Symposium No. 102 (Part I of the Liver Week Freiburg 1997), gives an update on the anatomy, physiology and pathophysiology of bile formation and secretion. Significant progress has been achieved in recent years due to the application of molecular biology which led to the identification of the specific transporters involved in bile formation and secretion. Furthermore, medical treatment in cholestatic liver diseases has made progress recently, due to the introduction of ursodeoxycholic acid and other medical procedures. Finally, cholestatic liver diseases are major indications for liver transplantation. Primary biliary cirrhosis has been the first disease where liver transplantation was shown to increase survival and improve quality of life. A completely separate, but also heterogeneous group are patients with paediatric cholestatic liver diseases. Some of them are also treated with liver transplantation, while in others genetic defects are being identified. The purpose of the symposium was to bring together well-known scientists and clinicians from around the world to discuss the recent progress on the physiology and pathophysiology of bile formation and secretion. Furthermore, the molecular basis of, and the therapeutic developments in cholestatic liver diseases and its progress were discussed. This volume deals with most, if not all, modern aspects of cholestatic liver diseases, with contributions on pathology, biochemistry, pharmacology, physiology, hepatology, immunology, paediatrics, and last but not least surgery.

Hepatotoxicity

Hyman J. Zimmerman
Hepatotoxicity Book PDF

Author : Hyman J. Zimmerman
Publisher : Lippincott Williams & Wilkins
Page : 848 pages
File Size : 47,7 Mb
Release : 1999
Category : Medical
ISBN : 0781719526

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Hepatotoxicity by Hyman J. Zimmerman Pdf

Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Fat Absorption

Arnis Kuksis
Fat Absorption Book PDF

Author : Arnis Kuksis
Publisher : CRC Press
Page : 582 pages
File Size : 53,6 Mb
Release : 2018-01-18
Category : Medical
ISBN : 9781351088893

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Fat Absorption by Arnis Kuksis Pdf

This book provides an authoritative and comprehensive source of information on the biochemical an metabolic aspects of digestion and absorption of different dietary fats and other lipids, with minimal discussion of the physical chemistry of the process, which has been covered in great detail in previous reviews. It is intended for both researchers and practitioners in the biomedical field who require detailed knowledge of the biomedical and metabolic transformations involed in the intestinal digestion and resynthesis of dietary fats and other lipids.

Pediatric Nutrition in Practice

B. Koletzko,J. Bhatia,Z.A. Bhutta,P. Cooper,M. Makrides,R. Uauy,W. Wang
Pediatric Nutrition in Practice Book PDF

Author : B. Koletzko,J. Bhatia,Z.A. Bhutta,P. Cooper,M. Makrides,R. Uauy,W. Wang
Publisher : Karger Medical and Scientific Publishers
Page : 334 pages
File Size : 50,5 Mb
Release : 2015-04-17
Category : Medical
ISBN : 9783318026917

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Pediatric Nutrition in Practice by B. Koletzko,J. Bhatia,Z.A. Bhutta,P. Cooper,M. Makrides,R. Uauy,W. Wang Pdf

There is no other time in life when the provision of adequate and balanced nutrition is of greater importance than during infancy and childhood. During this dynamic phase characterized by rapid growth, development and developmental plasticity, a sufficient amount and appropriate composition of nutrients both in health and disease are of key importance for growth, functional outcomes such as cognition and immune response, and the metabolic programming of long-term health and well-being. This compact reference text provides concise information to readers who seek quick guidance on practical issues in the nutrition of infants, children and adolescents. After the success of the first edition, which sold more than 50'000 copies in several languages, the editors prepared this thoroughly revised and updated second edition which focuses again on nutritional challenges in both affluent and poor populations around the world. Serving as a practical reference guide, this book will contribute to further improving the quality of feeding of healthy infants and children, as well as enhancing the standards of nutritional care in sick children.