Bio Nanoimaging

Author : Vladimir Uversky,Yuri Lyubchenko
Publisher : Academic Press
Page : 552 pages
File Size : 48,8 Mb
Release : 2013-11-05
Category : Technology & Engineering
ISBN : 9780123978219

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Bio-nanoimaging by Vladimir Uversky,Yuri Lyubchenko Pdf

Bio-Nanoimaging: Protein Misfolding & Aggregation provides a unique introduction to both novel and established nanoimaging techniques for visualization and characterization of misfolded and aggregated protein species. The book is divided into three sections covering: - Nanotechnology and nanoimaging technology, including cryoelectron microscopy of beta(2)-microglobulin, studying amyloidogensis by FRET; and scanning tunneling microscopy of protein deposits - Polymorphisms of protein misfolded and aggregated species, including fibrillar polymorphism, amyloid-like protofibrils, and insulin oligomers - Polymorphisms of misfolding and aggregation processes, including multiple pathways of lysozyme aggregation, misfolded intermediate of a PDZ domain, and micelle formation by human islet amyloid polypeptide Protein misfolding and aggregation is a fast-growing frontier in molecular medicine and protein chemistry. Related disorders include cataracts, arthritis, cystic fibrosis, late-onset diabetes mellitus, and numerous neurodegenerative diseases like Alzheimer's and Parkinson's. Nanoimaging technology has proved crucial in understanding protein-misfolding pathologies and in potential drug design aimed at the inhibition or reversal of protein aggregation. Using these technologies, researchers can monitor the aggregation process, visualize protein aggregates and analyze their properties. Provides practical examples of nanoimaging research from leading molecular biology, cell biology, protein chemistry, biotechnology, genetics, and pharmaceutical labs Includes over 200 color images to illustrate the power of various nanoimaging technologies Focuses on nanoimaging techniques applied to protein misfolding and aggregation in molecular medicine

Author : Alioscka A. Sousa,Michael J. Kruhlak
Publisher : Unknown
Page : 510 pages
File Size : 40,6 Mb
Release : 2013
Category : Diagnostic imaging
ISBN : 1627031375

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Nanoimaging by Alioscka A. Sousa,Michael J. Kruhlak Pdf

For more than a century, microscopy has been a centerpiece of extraordinary discoveries in biology. Along the way, remarkable imaging tools have been developed allowing scientists to dissect the complexity of cellular processes at the nano length molecular scales. Nanoimaging: Methods and Protocols presents a diverse collection of microscopy techniques and methodologies that provides guidance to successfully image cellular molecular complexes at nanometer spatial resolution. The book's four parts cover: (1) light microscopy techniques with a special emphasis on methods that go beyond the classic diffraction-limited imaging; (2) electron microscopy techniques for high-resolution imaging of molecules, cells and tissues, in both two and three dimensions; (3) scanning probe microscopy techniques for imaging and probing macromolecular complexes and membrane surface topography; and (4) complementary techniques on correlative microscopy, soft x-ray tomography and secondary ion mass spectrometry imaging. Written in the successful format of the Methods in Molecular Biology series, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step protocols, and notes on troubleshooting and avoiding known pitfalls. Authoritative and accessible, Nanoimaging: Methods and Protocols highlights many of the most exciting possibilities in microscopy for the investigation of biological structures at the nano length molecular scales.

Author : Zhe Liu
Publisher : Springer
Page : 117 pages
File Size : 45,5 Mb
Release : 2018-09-01
Category : Technology & Engineering
ISBN : 9789811048043

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Advances in Functional Micro-/Nanoimaging Probes by Zhe Liu Pdf

This book highlights the latest advances in functional micro/nano imaging probes and their applications for biomedical imaging and therapy. Given the rapid emergence of transdisciplinary research and applications in materials, chemical probes and translational medicine in recent years, scientists in these areas are expected to keep up to date on the latest technologies and advances to promote comprehensive innovations. Addressing this need, the book presents recently introduced features, emerging techniques, and new strategies, complemented by detailed illustrations. Covering the status quo and offering an outlook on the future, it benefits all readers with an interest in functional materials, especially micro/nano imaging materials for biomedical imaging applications, providing them with both vital updates and inspiration for their own research.

Author : Beth A. Goins,William T. Phillips
Publisher : CRC Press
Page : 308 pages
File Size : 53,6 Mb
Release : 2011-09-07
Category : Science
ISBN : 9789814267090

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Nanoimaging by Beth A. Goins,William T. Phillips Pdf

The first resource of its kind, this book covers cutting-edge research on the use of nanoparticles for in vivo diagnostic medical imaging and therapy. It discusses a variety of nanoparticles, including quantum dots, carbon nanotubes, dendrimers, gold nanoshells, metal nanorods, micelles, liposomes, polymers, MRI iron oxide particles, and microbubbles. Examples in the book include multifunctional nanoparticles that designed for multimodality imaging and simultaneous diagnostic and therapy (theranostic) applications.

Author : Mohammed Kuddus,Roohi
Publisher : Springer Nature
Page : 733 pages
File Size : 52,9 Mb
Release : 2021-06-21
Category : Science
ISBN : 9789811618239

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Bioplastics for Sustainable Development by Mohammed Kuddus,Roohi Pdf

This book provides the latest information on bioplastics and biodegradable plastics. The initial chapters introduce readers to the various sources and substrates for the synthesis of bioplastics and biodegradable plastics, and explain their general structure, physio-chemical properties and classification. In turn, the book discusses innovative methods for the production of bioplastics at the industrial level and for the microbial production of bioplastics. It highlights the processes that are involved in the conversion of agro-industrial waste into bioplastics, while also summarizing the mechanisms of biodegradation in bioplastics. The book addresses a range of biotechnological applications of bioplastics such as in agriculture, food packaging and pharmaceutical industry, as well as biomedical applications.

Author : Robert R. Alfano,Lingyan Shi
Publisher : William Andrew
Page : 610 pages
File Size : 41,8 Mb
Release : 2018-11-22
Category : Technology & Engineering
ISBN : 9780323480680

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Neurophotonics and Biomedical Spectroscopy by Robert R. Alfano,Lingyan Shi Pdf

Neurophotonics and Biomedical Spectroscopy addresses the novel state-of-the-art work in non-invasive optical spectroscopic methods that detect the onset and progression of diseases and other conditions, including pre-malignancy, cancer, Alzheimer’s disease, tissue and cell response to therapeutic intervention, unintended injury and laser energy deposition. The book then highlights research in neurophotonics that investigates single and multi-photon excitation optical signatures of normal/diseased nerve tissues and in the brain, providing a better understanding of the underlying biochemical and structural changes of tissues and cells that are responsible for the observed spectroscopic signatures. Topics cover a wide array of well-established UV, visible, NIR and IR optical and spectroscopic techniques and novel approaches to diagnose tissue changes, including: label free in vivo and ex vivo fluorescence spectroscopy, Stoke shift spectroscopy, spectral imaging, Resonance Raman spectroscopy, multiphoton two Photon excitation, and more. Provides an overview of the spectroscopic properties of tissue and tissue-light interaction, describing techniques to exploit these properties in imaging Explores the potential and significance of molecule-specific imaging and its capacity to reveal vital new information on nanoscale structures Offers a concise overview of different spectroscopic methods and their potential benefits for solving diagnostic and therapeutic problems

Author : Xuehai Yan
Publisher : John Wiley & Sons
Page : 933 pages
File Size : 51,9 Mb
Release : 2024-02-09
Category : Science
ISBN : 9783527841257

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Peptide Self-Assembly and Engineering by Xuehai Yan Pdf

Peptide Self-Assembly and Engineering State-of-the-art research in peptide self-assembly, with coverage of fundamental aspects of how peptides self-assemble and an extensive number of applications Peptide Self-Assembly and Engineering: Fundamentals, Structures, and Applications (2V set) covers the latest progresses in the field of peptide self-assembly and engineering, including the fundamental principles of peptide self-assembly, new theory of nucleation and growth, thermodynamics and kinetics, materials design rules, and precisely controlled structures and unique functions. The broad contents from this book enable readers to obtain a systematical and comprehensive knowledge in the field of peptide self-assembly and engineering. Contributed by the leading scientists and edited by a highly qualified academic and an authority in the field, Peptide Self-Assembly and Engineering includes information on: Emerging areas in peptide assembly, such as immune agents, bioelectronics, energy conversion, flexible sensors, biomimetic catalysis, and more Existing applications in biomedical engineering, nanotechnology, and photoelectronics, including tissue engineering, drug delivery, and biosensing devices History of peptide self-assembly for design of functional materials and peptides’ unique mechanical, optical, electronic, and biological properties Various solvent conditions, such as pH, ionic strength, and polarity, that can affect the structure and stability of peptide assemblies A very comprehensive reference covering the latest progresses in the field of peptide self-assembly and engineering, Peptide Self-Assembly and Engineering is an essential resource for all scientists performing research intersecting with the subject, including biochemists, biotechnologists, pharmaceutical chemists, protein chemists, materials scientists, and medicinal chemists.

Author : Yang Li,Diana Boraschi,Ben Zhong Tang,Pengfei Zhang
Publisher : Frontiers Media SA
Page : 171 pages
File Size : 46,5 Mb
Release : 2022-04-18
Category : Medical
ISBN : 9782889749324

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Immunological Effects of Nano-Imaging Materials by Yang Li,Diana Boraschi,Ben Zhong Tang,Pengfei Zhang Pdf

Author : Rodrigo Franco,Jonathan A Doorn,Jean-Christophe Rochet
Publisher : Royal Society of Chemistry
Page : 537 pages
File Size : 54,6 Mb
Release : 2017-07-25
Category : Medical
ISBN : 9781782621881

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Oxidative Stress and Redox Signalling in Parkinson’s Disease by Rodrigo Franco,Jonathan A Doorn,Jean-Christophe Rochet Pdf

Parkinson's Disease is the second most common neurodegenerative disorder affecting millions of people worldwide. In order to find neuroprotective strategies, a clear understanding of the mechanisms involved in the dopaminergic death of cells that progresses the disease is needed. Oxidative stress can be defined as an imbalance between the production of reactive species and the ability to detoxify them and their intermediates or by-products. Oxidative damage to lipids, proteins, and DNA has been detected in autopsies from individuals with Parkinson’s Disease and so links can be made between oxidative stress and Parkinson’s Disease pathogenesis. This book provides a thorough review of the mechanisms by which oxidative stress and redox signalling mediate Parkinson’s Disease. Opening chapters bring readers up to speed on basic knowledge regarding oxidative stress and redox signalling, Parkinson’s Disease, and neurodegeneration before the latest advances in this field are explored in detail. Topics covered in the following chapters include the role of mitochondria, dopamine metabolism, metal homeostasis, inflammation, DNA-damage and thiol-signalling. The role of genetics and gene-environment interactions are also explored before final chapters discuss the identification of potential biomarkers for diagnosis and disease progression and the future of redox/antioxidant based therapeutics. Written by recognized experts in the field, this book will be a valuable source of information for postgraduate students and academics, clinicians, toxicologists and risk assessment groups. Importantly, it presents the current research that might later lead to redox or antioxidant – based therapeutics for Parkinson’s disease.

Author : Shahnaz Subhan,Manashi Bagchi
Publisher : CRC Press
Page : 444 pages
File Size : 50,8 Mb
Release : 2017-09-27
Category : Medical
ISBN : 9781351649032

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Phytopharmaceuticals for Brain Health by Shahnaz Subhan,Manashi Bagchi Pdf

Research studies demonstrate diet and proper nutrition in conjunction with cognitive, mental, social, and physical activities can significantly help in improving brain health with advancing age, and potentially reduce the risk of cognitive decline. These studies of phytopharmaceuticals and medicinal plants, demonstrate the efficacy of Huperzine A, berry anthocyanins, trans-resveratrol, Ginkgo biloba, Bacopa monniera, Centella asiatica, tocotrienols, and palm oil in boosting brain health and physical well-being. In addition, consumption of marine fishes and general seafood is recommended for long-term nutritional intervention to preserve mental health, hinder neurodegenerative processes, and sustain cognitive capacities in humans. Omega-3 and omega-6 polyunsaturated fatty acids, n-3/n-6 PUFAs, flavonoids, and antioxidants prevent the initiation and progression of many neurological disorders. This book is a comprehensive review of phytopharmaceuticals impacting brain health with emphasis on diverse applications in food and nutrition sciences, biomedicine, neurology and other scientific and medical fields. It details available methods and contains numerous references making this the perfect guide for scientists who want to explore the fascinating world of phytopharmaceuticals with relation to brain health. Phytopharmaceuticals for Brain Health appeals to a diverse range of readers in industry, medical doctors, research and academia, including biologists, biochemists, food scientists, nutritionists and health professionals. Overall, this book brings a classic scenario of neurological problems to possible amelioration using novel nutraceuticals and functional foods.

Author : Wing-Fu Lai
Publisher : John Wiley & Sons
Page : 437 pages
File Size : 40,8 Mb
Release : 2023-05-10
Category : Technology & Engineering
ISBN : 9781119860587

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Materials Science and Engineering in Food Product Development by Wing-Fu Lai Pdf

Materials Science and Engineering in Food Product Development A comprehensive and accessible guide to the food development applications of cutting-edge materials science In Materials Science and Engineering in Food Product Development, distinguished researcher Wing-Fu Lai delivers an authoritative exploration of the roles played by materials science and engineering in food product development. In the book, the authors employ a practical, industrial perspective to illustrate how food products, especially functional foods, can benefit from the incorporation of materials science technologies. The book includes helpful glossary sections in each chapter, as well as important notes to highlight information useful to food manufacturers engaged in the real-world development and manufacture of foods. This book is appropriate for both early and advanced researchers interested in the design, improvement, and engineering of food products using the most current advances in food materials science. Readers will also find: A thorough overview of the most critical advances in food materials science Comprehensive explorations of a materials science approach to food product design and discussions of techniques for the characterization of food materials and products Practical discussions of the design and use of hydrogels, polymers, and lipid-based systems for food component encapsulation Comprehensive treatments of the optimization of pasting and textural properties of food products by rheological manipulation Perfect for students, researchers, and scholars in the fields of nutritional science, materials engineering, food science, food engineering, and nanotechnology, Materials Science and Engineering in Food Product Development will also benefit food manufacturing professionals during food product development.

Author : Inamuddin,Maha Khan,Mohammad Abu Jafar Mazumder,Mohammad Luqman
Publisher : Materials Research Forum LLC
Page : 175 pages
File Size : 46,7 Mb
Release : 2023-01-25
Category : Technology & Engineering
ISBN : 9781644902219

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Ion Exchange Resins by Inamuddin,Maha Khan,Mohammad Abu Jafar Mazumder,Mohammad Luqman Pdf

The book focuses on the applications of ion exchange resins in processes such as the separation and purification of proteins and vitamins, the selective separation of toxic metals and the separation and purification of bioactive molecules. Specific topics include drug delivery, clinical applications, water softening and sustained drug delivery. Keywords: Ion Exchange Resins, Protein Separation and Purification, Partition and Purgation of Vitamins, Toxic Heavy Metal Ions, Bioactive Molecules, Sustained Drug Release, Ion-Exchange Chromatography, Clinical Applications, Electrodialysis, Ultrasound, Water Softening.

Author : Yuan Jian-min,Zhou Huan-xiang
Publisher : World Scientific
Page : 328 pages
File Size : 54,6 Mb
Release : 2017-06-02
Category : Science
ISBN : 9789813202399

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Biophysics And Biochemistry Of Protein Aggregation: Experimental And Theoretical Studies On Folding, Misfolding, And Self-assembly Of Amyloidogenic Peptides by Yuan Jian-min,Zhou Huan-xiang Pdf

This book reviews current research on the important processes involved in neurodegenerative diseases (e.g. Alzheimer's disease) and the peptides and proteins involved in the amyloidogenic processes. It covers the design and developments of anti-amyloid inhibitors, and gives readers a fundamental understanding of the underlying oligomerization and aggregation processes of these diseases from both computational and experimental points of view.

Author : D. Anselmetti
Publisher : SPIE-International Society for Optical Engineering
Page : 146 pages
File Size : 47,9 Mb
Release : 2004
Category : Science
ISBN : UOM:39015059126857

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Biophotonics Micro- and Nano-imaging by D. Anselmetti Pdf

Proceedings of SPIE present the original research papers presented at SPIE conferences and other high-quality conferences in the broad-ranging fields of optics and photonics. These books provide prompt access to the latest innovations in research and technology in their respective fields. Proceedings of SPIE are among the most cited references in patent literature.

Author : Sheng Wang
Publisher : Unknown
Page : 286 pages
File Size : 52,7 Mb
Release : 2009
Category : Electronic
ISBN : UCAL:C3528071

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Interfacing Optics with Biology -- Optical Sensors, Actuators and Protein Lithography by Sheng Wang Pdf