Biocompatiblity

Author : Jean-Pierre Boutrand
Publisher : Woodhead Publishing
Page : 586 pages
File Size : 55,5 Mb
Release : 2019-11-21
Category : Medical
ISBN : 9780081026441

Get Book

Biocompatibility and Performance of Medical Devices by Jean-Pierre Boutrand Pdf

Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. Presents diverse insights from experts in government, industry and academia Delivers a comprehensive overview of testing and interpreting medical device performance Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market

Author : Masoud Mozafari
Publisher : Woodhead Publishing
Page : 0 pages
File Size : 51,8 Mb
Release : 2020-06-16
Category : Technology & Engineering
ISBN : 0081029675

Get Book

Handbook of Biomaterials Biocompatibility by Masoud Mozafari Pdf

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology.

Author : Gottfried Schmalz,Dorthe Arenholt Bindslev
Publisher : Springer Science & Business Media
Page : 392 pages
File Size : 53,5 Mb
Release : 2008-10-10
Category : Medical
ISBN : 9783540777823

Get Book

Biocompatibility of Dental Materials by Gottfried Schmalz,Dorthe Arenholt Bindslev Pdf

This book provides a comprehensive and scientifically based overview of the biocompatibility of dental materials. Up-to-date concepts of biocompatibility assessment are presented, as well as information on almost all material groups used in daily dentistry practice. Furthermore, special topics of clinical relevance (e.g,, environmental and occupational hazards and the diagnosis of adverse effects) are covered. The book will: improve the reader’s ability to critically analyze information provided by manufacturers supply a better understanding of the biocompatibility of single material groups, which will help the reader choose the most appropriate materials for any given patient and thus prevent adverse effects from developing provide insights on how to conduct objective, matter-of-fact discussions with patients about the materials to be used in dental procedures advise readers, through the use of well-documented concepts, on how to treat patients who claim adverse effects from dental materials feature clinical photographs that will serve as a reference when analyzing clinical symptoms, such as oral mucosa reactions.

Author : Masoud Mozafari
Publisher : Woodhead Publishing
Page : 759 pages
File Size : 49,7 Mb
Release : 2020-06-17
Category : Technology & Engineering
ISBN : 9780081029688

Get Book

Handbook of Biomaterials Biocompatibility by Masoud Mozafari Pdf

Handbook of Biomaterials Biocompatibility is a systematic reference on host response to different biomaterials, taking into account their physical, mechanical and chemical properties. The book reviews recent progress in the design and study of biomaterials biocompatibility, along with current understanding on how to control immune system response. Sections provide the fundamental theories and challenges of biomaterials biocompatibility, the role of different biomaterials physicochemical surface properties on cell responses, cell responses to different physicochemical properties of polymers, ceramics, metals, carbons and nanomaterials, and biomaterials in different tissues, such as the cardiac, nervous system, cartilage and bone. This resource will be suitable for those working in the fields of materials science, regenerative engineering, medicine, medical devices and nanotechnology. Reviews the fundamental theories and challenges of biomaterials biocompatibility, including an overview of the standards and regulations Provides an overview on the cellular and molecular mechanisms involved in host responses to biomaterials Systematically looks at cellular response and tissue response to a wide range of biomaterials, including polymers, metals, ceramics, alloys and nanomaterials

Author : Anişoara Cîmpean,Florin Miculescu
Publisher : MDPI
Page : 420 pages
File Size : 46,7 Mb
Release : 2020-03-10
Category : Technology & Engineering
ISBN : 9783039282166

Get Book

Biomaterials and Implant Biocompatibility by Anişoara Cîmpean,Florin Miculescu Pdf

The scientific advances in life sciences and engineering are constantly challenging, expanding, and redefining concepts related to the biocompatibility and safety of medical devices. New biomaterials, new products, and new testing regimes are being introduced to scientific research practices. In order to provide clinically predictive results and to ensure a high benefit–risk ratio for patients, we need to optimize material and implant characteristics, and to adapt performance and safety evaluation practices for these innovative medical devices. Various characteristics related to materials and implant development such as raw materials composition, implant surface morphology, design, geometry, porosity, and mechanical properties need to be thoroughly characterized before evaluating the biological performance of implants. Furthermore, with the increase of regulatory demands, biological evaluation needs to ensure appropriate models and methods for each implant development stage. This book is a result of the Special Issue of Materials on "Biomaterials and Implant Biocompatibility”, which focused on the recent progress in development, material testing, and the biocompatibility and bioactivity evaluation of various materials including, but not limited to, bioceramics, biopolymers, biometals, composite materials, biomimetic materials, hybrid biomaterials, and drug/device combinations for implants and prostheses with medical applications spanning from soft to hard tissue regeneration. The book covers aspects ranging from investigations into material characterization to in vitro and in vivo testing for the assessment of biological performance of advanced, novel biomaterials and implants.

Author : Prakash Srinivasan Timiri Shanmugam,Thamizharasan Sampath,Indumathy Jagadeeswaran
Publisher : Elsevier
Page : 264 pages
File Size : 54,9 Mb
Release : 2023-04-07
Category : Medical
ISBN : 9780323984928

Get Book

Biocompatibility Protocols for Medical Devices and Materials by Prakash Srinivasan Timiri Shanmugam,Thamizharasan Sampath,Indumathy Jagadeeswaran Pdf

Biocompatibility Protocols for Medical Devices and Materials provides comprehensive coverage of the basic science and toxicological testing protocols necessary for the risk assessment and safety analysis of medical devices and materials which are based on the ISO guidelines for body contact and duration of contact. The book begins with device/component selection for toxicological experiments and provides an introduction to topics such as sensitization, irritation tests, material-mediated pyrogenicity, and bacterial-mediated pyrogenicity. Toxicology-related chapters explain the protocols for cytotoxicity, acute systemic toxicity, repeated-exposure systemic toxicity, genotoxicity, carcinogenicity, and reproductive toxicity testing. Biocompatibility Protocols for Medical Devices and Materials is a practical guide that provides step-by-step toxicological protocols ranging from materials selection to data interpretation for toxicologists, biomedical researchers, healthcare professionals, product developers, and others working in risk assessment and safety analysis of medical devices. Explains the biocompatibility test protocols for medical devices Provides an overview about chemical characterization Describes toxicokinetic, carcinogenicity, and reproductive toxicity studies Discusses the basic points needed to leverage the data from another device

Author : Shunsheng Cao,Huijun Zhu
Publisher : Bentham Science Publishers
Page : 355 pages
File Size : 47,5 Mb
Release : 2014-10-13
Category : Medical
ISBN : 9781608058761

Get Book

The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application by Shunsheng Cao,Huijun Zhu Pdf

Frontiers in Biomaterials: The Design, Synthetic Strategies and Biocompatibility of Polymer Scaffolds for Biomedical Application, Volume 1 highlights the importance of biomaterials and their interaction with biological system. The need for the development of biomaterials as scaffold for tissue regeneration is driven by the increasing demands for materials that mimic functions of extracellular matrices of body tissues. This eBook covers the latest challenges on the biocompatibility of scaffold overtime after implantation and discusses the requirement of innovative technologies and strategies for the development of materials with long-lasting scaffold and biocompatibility functions. The contents of this eBook include chapters on cell-scaffold interactions in three dimensions, nanocrystalline diamond films for biomedical applications, bioceramics-design, synthesis and biological applications, polyester biomaterials for regenerative medicine, nanomaterials for skin regeneration and many more. This book is a valuable resource for MSc and PhD students , academic personnel and researchers seeking updated and critically important information on biomaterials and biomedical applications.

Author : Frederick H. Silver,David L. Christiansen
Publisher : Springer
Page : 0 pages
File Size : 46,7 Mb
Release : 2012-09-28
Category : Science
ISBN : 1461268168

Get Book

Biomaterials Science and Biocompatibility by Frederick H. Silver,David L. Christiansen Pdf

Adopting an interdisciplinary approach to the chemistry and physics of materials, their biocompatibility, and the consequences of implantation of such devices into the human body, this text introduces readers to the principles of polymer science and the study of metals, ceramics and composites, and also to the basic biology required to understand the nature of the host-transplant interface. Topics covered include the macromolecular components of cells and tissues, self-assembly processes, biological cascade systems, microscopic structure of cells and tissues, immunology, transplantation biology, and the pathobiology of wound healing. The materials science section includes the structures and properties of polymers, metals, ceramics and composites, and the processes for forming materials as well as the pathobiology of devices. The final two chapters deal with tissue engineering and the relations between the biology of cells and tissue transplantation, and the engineering of tissue replacements using passaged cells.

Author : Jonathan Black
Publisher : Marcel Dekker
Page : 408 pages
File Size : 41,7 Mb
Release : 1992
Category : Medical
ISBN : UOM:39015029233353

Get Book

Biological Performance of Materials by Jonathan Black Pdf

Author : Richard Shelton
Publisher : Woodhead Publishing
Page : 150 pages
File Size : 44,7 Mb
Release : 2016-10-18
Category : Technology & Engineering
ISBN : 9780081009437

Get Book

Biocompatibility of Dental Biomaterials by Richard Shelton Pdf

Biocompatibility of Dental Biomaterials details and examines the fundamentals of biocompatibililty, also including strategies to combat it. As biomaterials used in the mouth are subject to different problems than those associated with the general in vivo environment, this book examines these challenges, presenting the latest research and forward-thinking strategies. Explores the fundamentals of dental biomaterials and their compatibility Presents a thorough review of material specific issues

Author : Julian H. Braybrook
Publisher : John Wiley & Sons
Page : 256 pages
File Size : 49,7 Mb
Release : 1997-08-04
Category : Medical
ISBN : UOM:39015041353999

Get Book

Biocompatiblity by Julian H. Braybrook Pdf

This book presents both an overview and forward assessment of medical device materials and test methods. Highlighting the complex problem of host responses and related issues which may restrict the accuracy and reliability of existing test methodology, the book provides an unbiased appraisal of the requirements for biocompatibility and the approaches that have been developed to evaluate it.

Author : Robert A. Freitas
Publisher : Unknown
Page : 376 pages
File Size : 49,8 Mb
Release : 1999
Category : Biomedical engineering
ISBN : UCSC:32106018098522

Get Book

Nanomedicine by Robert A. Freitas Pdf

Nanosensors and nanorobots are not science fiction but part of nanomedicine, the newest direction in medicine. After touring medical history and defining molecular nanotechnology as the atomic-level control of molecular structures to create precisely targeted medical procedures, Freitas (Institute for Molecular Manufacturing, Palo Alto, CA) details such topics as molecular transport and device applications but leaves ethical debates to others. Appends data on nanodevice design, and human blood and cell types; and a 36-page glossary. Part of a three-volume work, due to be available online. Annotation copyrighted by Book News, Inc., Portland, OR.

Author : David Franklyn Williams
Publisher : Unknown
Page : 238 pages
File Size : 45,8 Mb
Release : 1976
Category : Medical
ISBN : UOM:39015006436334

Get Book

Biocompatibility of Implant Materials by David Franklyn Williams Pdf

Author : Frederick H. Silver,Charles Doillon
Publisher : Wiley-VCH
Page : 328 pages
File Size : 42,8 Mb
Release : 1989
Category : Technology & Engineering
ISBN : UOM:39015017712277

Get Book

Biocompatibility: Polymers by Frederick H. Silver,Charles Doillon Pdf

Band 1.

Author : H. Hildebrand,Maxime Champy
Publisher : Springer
Page : 404 pages
File Size : 46,8 Mb
Release : 1988
Category : Medical
ISBN : UOM:39015013801546

Get Book

Biocompatibility of Co-Cr-Ni Alloys by H. Hildebrand,Maxime Champy Pdf

For several years now scientific and medical sLaff have recognised the risks of toxicity of certain metals contained in alloys used in Lhe manufacture of biomaterials protheses, implants, and artificial organs. A number or scientific and industrial research centres have focussed their investigations in this direction and international societies and commissions have organised meetings with specialists from complementary disciplines in attendance in attempts to guage the importance of biological risks and to determine the toxicity of certain metals, with the aim of establishing preventive measures and guidelines. In the last century great efforts have been made to reduce unwanted biological effects caused by orthopaedic implants. The problems of pain and infection were overcome and the development of modern technology has resulted in a convincing decrease in corrosion problems and mechanical failure, such that ostosynthesis and endoprosthesis have rapidly progressed beyond the level of tentative investingation.llowever, a number of problems still remain to be solved, such as the influence of the material type on the healing process and its relative speed. The increasing use of cobalt-,chromium-and nickel-containing alloys in surgical and dental implants has raised various questions concerning the biological consequences of chronic internal release of these elements in the human body. A total of 55 delegates representing 16 countries heard presentations of fundamental aspects, local and remote tissue response, immunopathology, clinical aspects, and manufacturing qual ity control issues.