Biomarkers In Diabetes

Author : Vinood B. Patel,Victor R. Preedy
Publisher : Springer Nature
Page : 1163 pages
File Size : 50,9 Mb
Release : 2022-09-29
Category : Medical
ISBN : 9783031080142

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Biomarkers in Diabetes by Vinood B. Patel,Victor R. Preedy Pdf

This handbook focuses specifically on biomarkers in diabetes and provides a comprehensive understanding of this field. Readers will gain deep insights into bioinformatics and network analysis of biomarkers in diabetes, and will learn about circulating biomarkers in body fluids and specific pathological features of diabetes. Various animal models in diabetes research are also presented. In addition, like the previous volumes in this large reference series, the book provides a comprehensive look at genetics, cellular, and histological variables. The goal of this handbook is to provide information on markers of this disease to facilitate diagnosis, introduce new technologies, and ultimately improve health. It is a must for researchers as well as advanced students and physicians in the field of diabetes and biomarker research and application.

Author : Michael Pugia
Publisher : Unknown
Page : 128 pages
File Size : 53,5 Mb
Release : 2015
Category : Electronic
ISBN : 3319219286

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Inflammatory Pathways in Diabetes by Michael Pugia Pdf

This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spectroscopy, immunological assay design, measurement of cellular signal transduction and protease inhibition are used to clarify new biochemical pathways. Biomarker validation in animal models and correlations in humans for diagnostic clinical trials shed new light on the impact of diabetic diseases. The book reviews current understanding of inflammatory pathways in the pathophysiology of insulin resistance, metabolic syndrome, nephritis and other diabetic inflammatory conditions, and is the first to describe the impact of novel adipokines, protease inhibitors and complement markers. By presenting new methodologies for biomarker discovery, it provides a valuable resource for researchers studying clinical diagnosis, drug development, bio-analytical chemistry, proteomics and biochemistry. It is also useful for those conducting clinical and biological studies for targeted drug development. The methodologies and approaches can be applied to other markers, and the information will be helpful in the preparation of research grant applications.

Author : Mu Wang,Frank Witzmann
Publisher : BoD – Books on Demand
Page : 262 pages
File Size : 55,9 Mb
Release : 2016-08-17
Category : Medical
ISBN : 9789535125051

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Role of Biomarkers in Medicine by Mu Wang,Frank Witzmann Pdf

The use of biomarkers in basic and clinical research has become routine in many areas of medicine. They are accepted as molecular signatures that have been well characterized and repeatedly shown to be capable of predicting relevant disease states or clinical outcomes. In Role of Biomarkers in Medicine, expert researchers in their individual field have reviewed many biomarkers or potential biomarkers in various types of diseases. The topics address numerous aspects of medicine, demonstrating the current conceptual status of biomarkers as clinical tools and as surrogate endpoints in clinical research. This book highlights the current state of biomarkers and will aid scientists and clinicians to develop better and more specific biomarkers for disease management.

Author : Michael Pugia
Publisher : Springer
Page : 219 pages
File Size : 46,9 Mb
Release : 2015-10-20
Category : Medical
ISBN : 9783319219271

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Inflammatory Pathways in Diabetes by Michael Pugia Pdf

This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spectroscopy, immunological assay design, measurement of cellular signal transduction and protease inhibition are used to clarify new biochemical pathways. Biomarker validation in animal models and correlations in humans for diagnostic clinical trials shed new light on the impact of diabetic diseases. The book reviews current understanding of inflammatory pathways in the pathophysiology of insulin resistance, metabolic syndrome, nephritis and other diabetic inflammatory conditions, and is the first to describe the impact of novel adipokines, protease inhibitors and complement markers. By presenting new methodologies for biomarker discovery, it provides a valuable resource for researchers studying clinical diagnosis, drug development, bio-analytical chemistry, proteomics and biochemistry. It is also useful for those conducting clinical and biological studies for targeted drug development. The methodologies and approaches can be applied to other markers, and the information will be helpful in the preparation of research grant applications.

Author : Anca Pantea Stoian
Publisher : BoD – Books on Demand
Page : 442 pages
File Size : 42,5 Mb
Release : 2021-09-22
Category : Medical
ISBN : 9781838819033

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Type 2 Diabetes by Anca Pantea Stoian Pdf

Diabetes mellitus is a metabolic disease characterized by chronic high blood glucose levels. Of the various types of diabetes, type 2 diabetes is increasing in prevalence due to obesity, aging, sedentarism, and other factors. This book presents a novel approach to preventing and treating type 2 diabetes. Chapters cover such topics as diagnosis, pathogenesis, management, lifestyle and nutritional intervention, and systems to support early diagnosis and prevention of prediabetes.

Author : Di Wu
Publisher : Unknown
Page : 0 pages
File Size : 45,8 Mb
Release : 2015
Category : Diabetes
ISBN : OCLC:1110814466

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Discovery of Glyco-biomarkers for Diabetes and Complications in Diabetes by Di Wu Pdf

Author : Velandai Srikanth,Zoe Arvanitakis
Publisher : Academic Press
Page : 320 pages
File Size : 50,7 Mb
Release : 2018-02-09
Category : Medical
ISBN : 9780128096949

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Type 2 Diabetes and Dementia by Velandai Srikanth,Zoe Arvanitakis Pdf

Type 2 Diabetes and Dementia details the relationship between diabetes, dementia and the future of medicine and therapeutics. Chapters range from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment and prevention strategies, and the application of therapeutics. The book reflects the translational aspects of the current science in the field, with an emphasis on the display of neuroimaging and neuropathology. It contains contributions from world experts, and is ideal for clinicians and researchers in the fields of neurology, neuroscience, geriatric medicine and endocrinology. Presents a comprehensive overview that details the relationship between diabetes, dementia and the future of medicine and therapeutics Written for researchers and clinicians in neurology, neuroscience, geriatric medicine and endocrinology Includes topics ranging from epidemiology, clinical features, neuroimaging biomarkers, neuropathology, macrostructural and molecular mechanisms, risk assessment, prevention strategies and therapeutic applications

Author : Nobuyoshi Kosaka
Publisher : Humana
Page : 0 pages
File Size : 40,7 Mb
Release : 2016-08-23
Category : Medical
ISBN : 149396299X

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Circulating MicroRNAs by Nobuyoshi Kosaka Pdf

microRNAs (miRNAs) are small non-coding RNAs that regulate various biological phenomena, such as development and homeostasis. The dysregulation of miRNA leads to disease progression, particularly of cancer. In Circulating MicroRNAs: Methods and Protocols, expert researchers in the field detail recent advances in the isolation, purification and analysis of circulating miRNAs from a variety of sources for research. The book is divided into three main topics. The first section involves the study of secretory miRNAs in cell-cell communication, and the second, the study of circulating miRNAs in body fluids. The last describes the novel techniques used to study circulating miRNAs. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Circulating MicroRNAs: Methods and Protocols seeks to aid scientists in dealing with the recent advances of RNAi technology from the bench to the bedside.

Author : Awanish Kumar,Ashwini Kumar
Publisher : CRC Press
Page : 114 pages
File Size : 40,8 Mb
Release : 2020-10-12
Category : Health & Fitness
ISBN : 9781000197785

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Diabetes by Awanish Kumar,Ashwini Kumar Pdf

Diabetes: Epidemiology, Pathophysiology and Clinical Management aims to be the one-stop diabetes book for researchers, scientists and clinicians. It details the epidemiology, causes, molecular mechanisms, molecular markers, available drugs, experimental drugs, treatment modalities, and dietary and lifestyle approaches related to diabetes. It focuses on various molecular aspects of diabetes, and its related co-morbidities. Apart from the drug-based treatment approach based on international guidelines, this book also describes various surgical treatments available for cases of uncontrolled symptomatic diabetes. It also lays emphasis on the future possibilities of different approaches for diabetes management. Key Features Includes treatment guidelines and approaches to diabetes provided by major global diabetes associations Provides a thorough and comprehensive assimilation of detailed information and updates in the field of diabetes, helpful for researchers, scientists and clinicians Contains a chapter on anti-diabetic drugs, that covers both the commercially approved drugs as well as those that are in various phases of experimental, pre-clinical, and clinical trials

Author : Vijay Nambi
Publisher : Elsevier Health Sciences
Page : 400 pages
File Size : 42,5 Mb
Release : 2018-11-27
Category : Medical
ISBN : 9780323548366

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Biomarkers in Cardiovascular Disease by Vijay Nambi Pdf

Get a quick, expert overview of the ways in which biomarkers can be used to assess and guide the management of cardiovascular disease in the clinical setting. This concise, clinically-focused resource by Dr. Vijay Nambi consolidates today’s available information on this rapidly changing topic into one convenient resource, making it an ideal, easy-to-digest reference for cardiology practitioners, fellows, and residents. Covers lab standards and statistical interpretation of biomarkers with a clinical focus. Discusses relevant conditions such as hypertension and diabetes as key markers of injury and prognosis. Includes current information on biomarkers to assess and guide the management of heart failure, acute coronary syndrome, chest pain, shortness of breath, and more. Concludes the book with a timely chapter on how biomarkers may guide cardiologists in the future.

Author : Perez Kisakye Katambala
Publisher : GRIN Verlag
Page : 22 pages
File Size : 55,7 Mb
Release : 2016-08-19
Category : Medical
ISBN : 9783668278370

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The association between circulating levels of myeloperoxidase and type 2 diabetes in the Malmö diet and cancer cohort. An Assessment by Perez Kisakye Katambala Pdf

Seminar paper from the year 2016 in the subject Medicine - Internal Medicine, grade: 1, Lund University, course: Master Thesis, language: English, abstract: Chronic inflammation is suggested to play an important role in the pathogenesis of many chronic conditions. Chronic inflammatory biomarker Myeloperoxidase (MPO) has been reported in several studies that have investigated its role in cardiopulmonary events. However, there are limited studies that investigated its relationship with type 2 diabetes. In this text the relationship between plasma MPO concentration and lifestyle and socioeconomic factors and incident type 2 diabetes mellitus in the Malmö diet and cancer cohort (MDC) will be investigated. In order to do this a prospective cohort study of 4544 participants was drawn from MDC cardiovascular sub-cohort, with no type 2 diabetes at baseline between 1991 and 1996. Plasma MPO concentration were measured using Olink CVD kit. The cox proportional hazard regression analysis was used to determine the relationship of plasma MPO concentration with incident type 2 diabetes.

Author : Filipe Palavra,Flávio Reis,Daniela Marado,Armando Sena
Publisher : Springer
Page : 165 pages
File Size : 48,5 Mb
Release : 2015-04-11
Category : Medical
ISBN : 9783319160184

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Biomarkers of Cardiometabolic Risk, Inflammation and Disease by Filipe Palavra,Flávio Reis,Daniela Marado,Armando Sena Pdf

This book discusses recent advances in the area of cardiometabolic risk biomarkers of chronic inflammatory and cardiovascular disorders. Tackling the topic in a systematic manner, the book starts with an introduction to cardiometabolic risk and its clinical relevance, comparing emergent and classical biomarkers. It then goes on to discuss cardiometabolic risk biomarkers in a range of diseases, including diabetes, ischemic stroke and neurodegenerative disorders. Biomarkers of Cardiometabolic Risk, Inflammation and Disease is aimed at doctors specializing in internal medicine, neurology, cardiology, rheumatology, nephrology or endocrinology and will also be of interest to GPs, trainee doctors and clinical and basic researchers working on cardiovascular and autoimmune disorders.

Author : Ina-Maria Rückert
Publisher : Unknown
Page : 86 pages
File Size : 47,7 Mb
Release : 2013
Category : Electronic
ISBN : 3897837889

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Epidemiological Facets of Type 2 Diabetes Mellitus by Ina-Maria Rückert Pdf

Author : Mahmood S. Mozaffari
Publisher : Springer Science & Business Media
Page : 549 pages
File Size : 45,9 Mb
Release : 2013-03-13
Category : Medical
ISBN : 9789400759718

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New Strategies to Advance Pre/Diabetes Care: Integrative Approach by PPPM by Mahmood S. Mozaffari Pdf

This book is intended to provide up-to-date and emerging information in the field of diabetes mellitus with a focus on preventive, predictive and personalized medicine.

Author : Max Kuhn,Kjell Johnson
Publisher : Springer Science & Business Media
Page : 600 pages
File Size : 49,5 Mb
Release : 2013-05-17
Category : Medical
ISBN : 9781461468493

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Applied Predictive Modeling by Max Kuhn,Kjell Johnson Pdf

Applied Predictive Modeling covers the overall predictive modeling process, beginning with the crucial steps of data preprocessing, data splitting and foundations of model tuning. The text then provides intuitive explanations of numerous common and modern regression and classification techniques, always with an emphasis on illustrating and solving real data problems. The text illustrates all parts of the modeling process through many hands-on, real-life examples, and every chapter contains extensive R code for each step of the process. This multi-purpose text can be used as an introduction to predictive models and the overall modeling process, a practitioner’s reference handbook, or as a text for advanced undergraduate or graduate level predictive modeling courses. To that end, each chapter contains problem sets to help solidify the covered concepts and uses data available in the book’s R package. This text is intended for a broad audience as both an introduction to predictive models as well as a guide to applying them. Non-mathematical readers will appreciate the intuitive explanations of the techniques while an emphasis on problem-solving with real data across a wide variety of applications will aid practitioners who wish to extend their expertise. Readers should have knowledge of basic statistical ideas, such as correlation and linear regression analysis. While the text is biased against complex equations, a mathematical background is needed for advanced topics.