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Biomarkers In Genitourinary Cancers Volume Ii Book in PDF, ePub and Kindle version is available to download in english. Read online anytime anywhere directly from your device. Click on the download button below to get a free pdf file of Biomarkers In Genitourinary Cancers Volume Ii book. This book definitely worth reading, it is an incredibly well-written.
Author : Riccardo Tellini,Alfredo Berruti,Michele Marchioni,Takeshi Yuasa
Publisher : Frontiers Media SA
Page : 305 pages
File Size : 49,7 Mb
Release : 2022-11-14
Category : Medical
ISBN : 9782832505373
Author : Eric A. Singer,Paula Alexandra Quintela Videira,Marco Borghesi
Publisher : Frontiers Media SA
Page : 226 pages
File Size : 53,9 Mb
Release : 2022-05-25
Category : Medical
ISBN : 9782889762156
Author : Franco Dammacco,Franco Silvestris
Publisher : Academic Press
Page : 718 pages
File Size : 41,5 Mb
Release : 2018-10-30
Category : Medical
ISBN : 9780128117866
Oncogenomics: From Basic Research to Precision Medicine offers a thorough survey of precision medicine and its diagnostic and therapeutic applications in oncology. Gathering contributions from leading international researchers in the field, chapters examine recent translational advances in oncogenomic methods and technologies, detailing novel molecular classifications of tumors as well as diagnostic and prognostic biomarkers for various types of cancers including pancreatic, gastrointestinal, breast, hematological, lung, osteotropic, genitourinary, and skin cancers. This book provides a foundation for clinical oncologists, human geneticists, and physicians to develop new targeted cancer treatments and incorporate genomic medicine into clinical practice, with particular attention paid to noninvasive diagnostic techniques such as the liquid biopsy and molecular characterization of solid malignancies. Provides clinical oncologists, human geneticists, physicians, and students with a thorough understanding of current diagnostic and prognostic applications of genomic methods and technologies to a variety of solid malignancies Employs current knowledge in oncogenomics towards developing therapeutic interventions for various cancer types Features a team of internationally recognized researchers and physicians in clinical oncology, oncogenomics and precision medicine
Author : Rodolfo Montironi,Matteo Santoni,Alessia Cimadamore,Antonio Lopez-Beltran,Liang Cheng
Publisher : Frontiers Media SA
Page : 79 pages
File Size : 48,9 Mb
Release : 2019-07-31
Category : Electronic
ISBN : 9782889459292
The identification of effective biomarkers has becoming a major focus in cancer research, mainly due to the necessity of selecting potentially responsive patients in order to improve their outcomes, as well as to reduce the toxicity and costs related to ineffective treatments. In genitourinary tumors, the lack of biomarkers does not allow for the development of personalized strategies for a single patient, thus representing a major goal in this field. This eBook includes the description of these emerging techniques and identify the most promising biomarkers in genitourinary tumors.
Author : Vincent T. DeVita,Theodore S. Lawrence,Steven A. Rosenberg
Publisher : Lippincott Williams & Wilkins
Page : 2049 pages
File Size : 55,5 Mb
Release : 2016-03-18
Category : Medical
ISBN : 9781496354211
Selected from the world’s leading comprehensive cancer textbook, this tightly focused resource provides you with the practical, cutting-edge information you need to provide the best cancer care to each patient. Prostate and Other Genitourinary Cancers: Cancer: Principles & Practice of Oncology, 10th Edition, offers a comprehensive and balanced view of this rapidly changing field, meeting the needs of oncology practitioners, fellows, and others who need an in-depth understanding of prostate and GU cancer. The print reference gives you the solid, dependable guidance you’ve come to expect from this outstanding title, and the Inkling version features new quarterly updates written by a team of experts selected by the authors.
Author : Hui Dai,Jun Pang,Yu Fan,Jianzhong Ai,Youqiang Ke,Lu Yang
Publisher : Frontiers Media SA
Page : 374 pages
File Size : 41,7 Mb
Release : 2024-04-02
Category : Medical
ISBN : 9782832547106
Genitourinary tumors consist of a large variety of malignancies located in the urinary and the reproductive systems, mainly including prostate cancer, bladder cancer, and renal tumors. Apart from surgeries, various systemic treatments have been used for the whole-course management of genitourinary tumors, including radiation therapy, chemotherapy, and hormonal therapy. However, the characteristics of progression, metastasis, and drug resistance deriving from tumors require and breed novel treatments. Furthermore, exploring biomarkers of genitourinary tumors at the early stage is also beneficial to strengthen the management of patients with tumors. Additionally, the diagnostic and prognostic value of the potential biomarkers for immunotherapy and combined therapy of genitourinary tumors are underexplored. On the basis of precision treatments, the advent of immune-based therapies, including immune checkpoint inhibitors (ICIs, antibodies targeting PD-L1 /PD-1 and CTLA-4 pathways), tumor vaccines, and other therapies, has extended the scope of treatment modalities. FDA has until now approved the clinical application of immune checkpoint inhibitors in a wide range of diseases including some types of genitourinary tumors, whereas not all patients with genitourinary tumors are suitable for immune-based therapies, therefore, the understanding of its underlying mechanism is key to develop effective treatments based on current ICI-based immunotherapy.
Author : Gary S. Stein,Kimberly P. Luebbers
Publisher : John Wiley & Sons
Page : 708 pages
File Size : 50,5 Mb
Release : 2019-09-18
Category : Science
ISBN : 9781118962886
A guide to recent insights into the genetic and epigenetic parameters of cancer biology and pathology and emerging clinical applications The thoroughly updated second edition of The Biology and Treatment of Cancer, now titled Cancer: Prevention, Early Detection, Treatment and Recovery, goes beyond reviewing the fundamental properties of cancer biology and the relevant issues associated with treatment of the disease. The new edition contains coverage of additional "patient centric" topics and presents cancer biology with selection of topics, facts, and perspectives written in easy-to-understand terms. With contributions from noted experts, the book explores recent advances in the understanding of cancer including breakthroughs in the molecular and cellular basis of cancer and provides strategies for approaching cancer prevention, early detection, and treatment. The authors incorporate recent information on the genetic and epigenetic parameters of cancer biology and pathology with indications of emerging clinical applications. The text offers a unique guide to cancer prevention, early detection, treatment, and recovery for students, caregivers, and most importantly cancer patients. This significant book: Incorporates current insight into the genetic and epigenetic parameters of cancer biology and pathology and information on emerging clinical applications Contains contributions from leaders in cancer research, care, and clinical trials Offers an accessible guide to an accurate and balanced understanding of cancer and the cancer patient Focuses on the importance of cancer prevention, early detection, treatment, and survivorship Written for medical students, students of cancer biology, and caregivers and cancer patients, Cancer: Prevention, Early Detection, Treatment and Recovery offers an authoritative overview of the challenges and opportunities associated with cancer biology, cancer research, and the spectrum of clinical considerations.
Author : Primo N. Lara,Eric Jonasch
Publisher : Springer
Page : 402 pages
File Size : 41,6 Mb
Release : 2015-06-10
Category : Medical
ISBN : 9783319179032
Kidney Cancer: Principles and Practice is a comprehensive and interdisciplinary textbook that encompasses all clinically relevant aspects of the disease. This new edition has been extensively updated and includes brand new material covering the most recent developments in kidney cancer diagnosis and therapy. The user-friendly and clinically oriented content of the book guarantees that it will be of great interest to a wide range of medical professionals, and every effort has been made to ensure that contributions are both easy to understand and directly related to patient care. Content presentation departs from the usual dense chapter format featuring a lengthy series of paragraphs. Instead, each chapter contains several boxed sections, including one that summarizes essential "take home points" for the busy clinician and another that presents a patient-oriented case highlighting the clinical application of elements discussed in that chapter. In addition, accessible original images, illustrations, and diagrams (some in full color) are used to simplify particularly complex material. This book will be of value for clinicians, researchers, residents, fellows, students, and knowledgeable lay people. The contributors comprise an international group of authors with expertise in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others.
Author : Daniela Terracciano,Matteo Ferro,Carlo Buonerba
Publisher : Frontiers Media SA
Page : 323 pages
File Size : 40,6 Mb
Release : 2022-06-14
Category : Medical
ISBN : 9782889762026
Author : Primo N. Lara, Jr.,Eric Jonasch
Publisher : Springer Science & Business Media
Page : 305 pages
File Size : 51,6 Mb
Release : 2012-01-10
Category : Medical
ISBN : 9783642218583
This interdisciplinary textbook encompasses all clinically relevant aspects of the disease and is designed to be as user-friendly as possible in order to meet the needs of the busy practitioner. To this end, the informative text is complemented by helpful boxed sections that present essential ‘take home’ points and illustrative patient-oriented cases. Original high-quality images, some in color, are included whenever necessary to simplify particularly complex material. The authors are an international group of acknowledged experts in kidney cancer epidemiology, molecular biology, pathology, diagnosis, clinical features, staging, prognostic and predictive factors, surgery, systemic therapy, and emerging investigational approaches, among others. This clinically oriented volume will be of great interest to clinicians, researchers, residents, and fellows, as well as to students and knowledgeable lay people.
Author : Adam Feldman
Publisher : Elsevier Health Sciences
Page : 177 pages
File Size : 47,9 Mb
Release : 2022-11-24
Category : Medical
ISBN : 9780323940207
In this issue of Urologic Clinics of North America, guest editor Dr. Adam Feldman brings his considerable expertise to the topic of Biomarkers in Urology. The use of biomarkers in clinical practice can range from screening, to refined detection in an at-risk population, to risk stratification following diagnosis, to prognostication following therapy. A better understanding of tumor biology and genetic heterogeneity will lead clinicians to adopt clinical paradigms that utilize sequences of biomarker assessments. In this issue, key experts help you remain at the forefront of the care of urologic malignancies by providing a timely update on emerging biomarkers in urology. Contains 15 practice-oriented topics including biomarkers in pediatric urology; unleashing the urinary microbiome in benign urologic disease; biomarkers for detection and assessment of clinically significant prostate cancer; biomarkers in testicular cancer: classic tumor markers and beyond; and more. Provides in-depth clinical reviews on biomarkers in urology, offering actionable insights for clinical practice. Presents the latest information on this timely, focused topic under the leadership of experienced editors in the field. Authors synthesize and distill the latest research and practice guidelines to create clinically significant, topic-based reviews.
Author : Giampietro Gasparini,Daniel F. Hayes
Publisher : Springer Science & Business Media
Page : 335 pages
File Size : 40,8 Mb
Release : 2008-01-17
Category : Medical
ISBN : 9781592599158
Expert laboratory and clinical researchers from around the world review how to design and evaluate studies of tumor markers and examine their use in breast cancer patients. The authors cover both the major advances in sophisticated molecular methods and the state-of-the-art in conventional prognostic and predictive indicators. Among the topics discussed are the relevance of rigorous study design and guidelines for the validation studies of new biomarkers, gene expression profiling by tissue microarrays, adjuvant systemic therapy, and the use of estrogen, progesterone, and epidermal growth factor receptors as both prognostic and predictive indicators. Highlights include the evaluation of HER2 and EGFR family members, of p53, and of UPA/PAI-1; the detection of rare cells in blood and marrow; and the detection and analysis of soluble, circulating markers.
Author : Michel Bolla,Hendrik van Poppel
Publisher : Springer
Page : 422 pages
File Size : 51,6 Mb
Release : 2017-01-09
Category : Medical
ISBN : 9783319427690
This book, now in an extensively revised second edition, provides an exhaustive review of the state of the art in the management of prostate cancer, from screening to treatment, with emphasis on a multidisciplinary approach. The editors are very excited about the outstanding new or updated contributions from the different expert authors. The opening chapters address basic aspects including epidemiology, pathology, biology, genetics, and chemoprevention. The role of individual and mass screening is carefully appraised, and extensive attention is devoted to diagnosis and clinical work-up by means of recently implemented investigations such as multiparametric MRI and choline PET-CT. The use of active surveillance is examined in detail. Subsequent chapters discuss the different therapies that may be employed: open and minimally invasive, including robot-assisted, radical prostatectomy, the various forms of radiation treatment, high-intensity focused ultrasound, cryotherapy, hormonal manipulations, chemotherapy, targeted therapies, and immunotherapy. Up-to-date results from practice-changing phase III randomized clinical trials are included and special insights are provided into the interpretation of results and the patient’s perspective.
Author : Visith Thongboonkerd
Publisher : John Wiley & Sons
Page : 423 pages
File Size : 54,8 Mb
Release : 2009-12-21
Category : Science
ISBN : 9783527319749
Based on research and results from the international Human Kidney and Urine Proteome Project, this handbook and reference presents current methods and protocols for the analysis of human kidney and urine. The world's leading experts cover everything from basic techniques for routine analysis to advanced methods for difficult samples or analytes. Written with the practitioner in mind, all the methods and techniques are described with step-by-step protocols backed by much valuable practical advice taken from real life experiments.
Author : Gabriel D. Dakubo
Publisher : Springer Nature
Page : 296 pages
File Size : 49,9 Mb
Release : 2019-08-29
Category : Medical
ISBN : 9783030247256
The ability to measure and monitor cancer biomarkers in “body fluid biopsy” should greatly impact oncologic practice. “Biomarkers in Proximal Fluids”, the third of the “Cancer Biomarkers in Body Fluids” series details cancer signatures in none or minimally circulating body fluids including saliva, sputum, bronchoalveolar lavage fluid, exhaled breath condensate, nipple aspirate fluid, gastric and pancreatic juice, stool, urine, and prostatic, peritoneal and cerebrospinal fluid. These fluids are enriched with biomarkers, especially those emanating from cells of the proximal tissue. Chapter 1 examines the global burden of cancer and the need for regional efforts at primary prevention, early detection and patient care. Chapters 2-12 address tissue-specific biomarkers in associated body fluids. The tumor interstitial fluid as a microenvironment rich in cancer biomarkers is detailed in chapter 13, while chapter 14 looks at the human body fluid microbiome and its evolving role in cancer. Commercially available assays using proximal fluids are examined at the end of the respective chapters. This book complements its predecessors and is equally useful to oncologists, cancer researchers, clinicians, medical students, nurses, diagnostic laboratory and pharmaceutical industry personnel.
