Biomarkers Of Radiation In The Environment

Author : Michael D. Wood,Carmel E. Mothersill,Gohar Tsakanova,Tom Cresswell,Gayle E. Woloschak
Publisher : Springer Nature
Page : 333 pages
File Size : 40,7 Mb
Release : 2022-04-04
Category : Medical
ISBN : 9789402421019

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Biomarkers of Radiation in the Environment by Michael D. Wood,Carmel E. Mothersill,Gohar Tsakanova,Tom Cresswell,Gayle E. Woloschak Pdf

This proceedings volume results from the NATO Advanced Research Workshop on 'Biomarkers of Radiation in the Environment: Robust Tools for Risk Assessment (BRITE)’. The BRITE workshop discussed insights from cancer research, epigenetics, non-human and human risk assessment, since many of the state-of-the-art biomarkers being developed for humans deserve consideration for environmental applications and vice versa. Sessions were very wide-ranging covering methods, mechanisms, cross disciplinary application and regulation. The chapters in this book have been grouped into five major themes that were covered by the BRITE workshop: · Techniques for biomarker development · Low-dose effect mechanisms · Biomarkers for risk evaluation · Biomarkers in wildlife · Biomarker use and responses Each chapter has been written independently and reflects the views of the chapter author(s). Therefore, the readers can form their own balanced view of the different perspectives on biomarkers of radiation in the environment. Given the breadth of topics covered and the state-of-the-art perspectives shared by leading experts in their respective fields, this book should form a valuable resource for anyone with an interest in how biomarkers can be used to improve our understanding of radiation in the environment and its potential impacts.

Author : David B. Peakall,Colin Harold Walker,Pawel Migula
Publisher : Springer Science & Business Media
Page : 356 pages
File Size : 53,9 Mb
Release : 1999
Category : Biochemical markers
ISBN : CORNELL:31924067916191

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Biomarkers by David B. Peakall,Colin Harold Walker,Pawel Migula Pdf

Many areas of Eastern Europe have been polluted to an extent unknown in the West. Four such sites - Kola Peninsula, northern Bohemia, upper Vistula Basin, and Katowice - have been identified and detailed accounts of the pollution at these sites are given. The current status of the use of biomarkers in hazard assessment is given by several scientists from NATO countries. Four working groups, comprising scientists working on the polluted sites and western scientists with expertise in biomarkers, examine the use of biomarkers to assess the environmental health of each of these areas and make recommendations on the future direction of remedial action in these areas.

Author : John F. McCarthy,Lee R. Shugart
Publisher : Unknown
Page : 457 pages
File Size : 43,8 Mb
Release : 2018
Category : Electronic books
ISBN : 1351095617

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Biomarkers of Environmental Contamination by John F. McCarthy,Lee R. Shugart Pdf

"How can biological markers help assess and predict human health risks? Find out the answers to this question and others in this timely new book examining the use of biological markers in animals and plants for evaluating the ecological and health effects of environmental contamination. The book explains the concept of environmental sentinels, presents example of field studies and discusses the utility of biomarkers within a risk analysis paradigm. Anyone who needs to know how to assess and predict environmental contamination should consider this book essential reading."--Provided by publisher.

Author : Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction
Publisher : National Academies Press
Page : 657 pages
File Size : 54,5 Mb
Release : 2001-10-17
Category : Medical
ISBN : 9780309072823

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Clearing the Smoke by Institute of Medicine,Board on Health Promotion and Disease Prevention,Committee to Assess the Science Base for Tobacco Harm Reduction Pdf

Despite overwhelming evidence of tobacco's harmful effects and pressure from anti-smoking advocates, current surveys show that about one-quarter of all adults in the United States are smokers. This audience is the target for a wave of tobacco products and pharmaceuticals that claim to preserve tobacco pleasure while reducing its toxic effects. Clearing the Smoke addresses the problems in evaluating whether such products actually do reduce the health risks of tobacco use. Within the context of regulating such products, the committee explores key questions: Does the use of such products decrease exposure to harmful substances in tobacco? Is decreased exposure associated with decreased harm to health? Are there surrogate indicators of harm that could be measured quickly enough for regulation of these products? What are the public health implications? This book looks at the types of products that could reduce harm and reviews the available evidence for their impact on various forms of cancer and other major ailments. It also recommends approaches to governing these products and tracking their public health effects. With an attitude of healthy skepticism, Clearing the Smoke will be important to health policy makers, public health officials, medical practitioners, manufacturers and marketers of "reduced-harm" tobacco products, and anyone trying to sort through product claims.

Author : National Research Council,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on the Analysis of Cancer Risks in Populations near Nuclear Facilitiesâ¬"Phase I
Publisher : National Academies Press
Page : 424 pages
File Size : 50,6 Mb
Release : 2012-06-29
Category : Medical
ISBN : 9780309255714

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Analysis of Cancer Risks in Populations Near Nuclear Facilities by National Research Council,Division on Earth and Life Studies,Nuclear and Radiation Studies Board,Committee on the Analysis of Cancer Risks in Populations near Nuclear Facilitiesâ¬"Phase I Pdf

In the late 1980s, the National Cancer Institute initiated an investigation of cancer risks in populations near 52 commercial nuclear power plants and 10 Department of Energy nuclear facilities (including research and nuclear weapons production facilities and one reprocessing plant) in the United States. The results of the NCI investigation were used a primary resource for communicating with the public about the cancer risks near the nuclear facilities. However, this study is now over 20 years old. The U.S. Nuclear Regulatory Commission requested that the National Academy of Sciences provide an updated assessment of cancer risks in populations near USNRC-licensed nuclear facilities that utilize or process uranium for the production of electricity. Analysis of Cancer Risks in Populations near Nuclear Facilities: Phase 1 focuses on identifying scientifically sound approaches for carrying out an assessment of cancer risks associated with living near a nuclear facility, judgments about the strengths and weaknesses of various statistical power, ability to assess potential confounding factors, possible biases, and required effort. The results from this Phase 1 study will be used to inform the design of cancer risk assessment, which will be carried out in Phase 2. This report is beneficial for the general public, communities near nuclear facilities, stakeholders, healthcare providers, policy makers, state and local officials, community leaders, and the media.

Author : David B. Peakall
Publisher : Springer Science & Business Media
Page : 312 pages
File Size : 46,9 Mb
Release : 2012-12-06
Category : Science
ISBN : 9789401123464

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Animal Biomarkers as Pollution Indicators by David B. Peakall Pdf

Ecotoxicology is a relatively new scientific discipline. Indeed, it might be argued that it is only during the last 5-10 years that it has come to merit being regarded as a true science, rather than a collection of procedures for protecting the environment through management and monitoring of pollutant discharges into the environment. The term 'ecotoxicology' was first coined in the late sixties by Prof. Truhaut, a toxicologist who had the vision to recognize the importance of investigating the fate and effects of chemicals in ecosystems. At that time, ecotoxicology was considered a sub-discipline of medical toxicology. Subsequently, several attempts have been made to portray ecotoxicology in a more realistic light. Notably, both F. Moriarty (1988) and F. Ramade (1987) emphasized in their books the broad basis of ecotoxicology, encompassing chemical and radiation effects on all components of ecosystems. In doing so, they and others have shifted concern from direct chemical toxicity to man, to the far more subtle effects that pollutant chemicals exert on natural biota. Such effects potentially threaten the existence of all life on Earth. Although I have identified the sixties as the era when ecotoxicology was first conceived as a coherent subject area, it is important to acknowledge that studies that would now be regarded as ecotoxicological are much older. Wherever people's ingenuity has led them to change the face of nature significantly, it has not escaped them that a number of biological con sequences, often unfavourable, ensue.

Author : W. G. Eisert,M. L. Mendelsohn
Publisher : Springer Science & Business Media
Page : 343 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Medical
ISBN : 9783642693342

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Biological Dosimetry by W. G. Eisert,M. L. Mendelsohn Pdf

In October 1982, a small international symposium was held at the Gesellschaft fUr Strahlen- und Umweltforschung mbH (GSF) in Munich as a satellite meeting of the IX International Conference on Analytical Cytology. The symposium focussed on cytometric approaches to biological dosimetry, and was, to the best of our knowledge, the first meeting on this subject ever held. There was strong encouragement from the 75 attendees and from others to publish a proceedings of the symposium. Hence this book, containing 30 of the 36 presentations, has been assembled. Dosimetry, the accurate and systematic determination of doses, usually refers to grams of substance administered or rads of ionization or some such measure of exposure of a patient, a victim or an experimental system. The term also can be used to describe the quantity of an ultimate, active agent as delivered to the appropriate target material within a biological system. Thus, for mutagens, one can speak of DNA dosimetry, meaning the number of adducts produced in the DNA of target cells such as bone-mar row stem cells or spermatogonia.

Author : Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation,National Research Council
Publisher : National Academies Press
Page : 422 pages
File Size : 49,7 Mb
Release : 2006-03-23
Category : Science
ISBN : 9780309133340

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Health Risks from Exposure to Low Levels of Ionizing Radiation by Committee to Assess Health Risks from Exposure to Low Levels of Ionizing Radiation,National Research Council Pdf

This book is the seventh in a series of titles from the National Research Council that addresses the effects of exposure to low dose LET (Linear Energy Transfer) ionizing radiation and human health. Updating information previously presented in the 1990 publication, Health Effects of Exposure to Low Levels of Ionizing Radiation: BEIR V, this book draws upon new data in both epidemiologic and experimental research. Ionizing radiation arises from both natural and man-made sources and at very high doses can produce damaging effects in human tissue that can be evident within days after exposure. However, it is the low-dose exposures that are the focus of this book. So-called “late” effects, such as cancer, are produced many years after the initial exposure. This book is among the first of its kind to include detailed risk estimates for cancer incidence in addition to cancer mortality. BEIR VII offers a full review of the available biological, biophysical, and epidemiological literature since the last BEIR report on the subject and develops the most up-to-date and comprehensive risk estimates for cancer and other health effects from exposure to low-level ionizing radiation.

Author : Manosij Ghosh,Radu Corneliu Duca
Publisher : Frontiers Media SA
Page : 221 pages
File Size : 44,9 Mb
Release : 2021-12-21
Category : Science
ISBN : 9782889718344

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Biomarkers of Exposure, Effect and Susceptibility to Environmental and Occupational Chemicals by Manosij Ghosh,Radu Corneliu Duca Pdf

Author : Thomas S. Bianchi,Elizabeth A. Canuel
Publisher : Princeton University Press
Page : 417 pages
File Size : 51,8 Mb
Release : 2011-02-28
Category : Science
ISBN : 9781400839100

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Chemical Biomarkers in Aquatic Ecosystems by Thomas S. Bianchi,Elizabeth A. Canuel Pdf

This textbook provides a unique and thorough look at the application of chemical biomarkers to aquatic ecosystems. Defining a chemical biomarker as a compound that can be linked to particular sources of organic matter identified in the sediment record, the book indicates that the application of these biomarkers for an understanding of aquatic ecosystems consists of a biogeochemical approach that has been quite successful but underused. This book offers a wide-ranging guide to the broad diversity of these chemical biomarkers, is the first to be structured around the compounds themselves, and examines them in a connected and comprehensive way. This timely book is appropriate for advanced undergraduate and graduate students seeking training in this area; researchers in biochemistry, organic geochemistry, and biogeochemistry; researchers working on aspects of organic cycling in aquatic ecosystems; and paleoceanographers, petroleum geologists, and ecologists. Provides a guide to the broad diversity of chemical biomarkers in aquatic environments The first textbook to be structured around the compounds themselves Describes the structure, biochemical synthesis, analysis, and reactivity of each class of biomarkers Offers a selection of relevant applications to aquatic systems, including lakes, rivers, estuaries, oceans, and paleoenvironments Demonstrates the utility of using organic molecules as tracers of processes occurring in aquatic ecosystems, both modern and ancient

Author : Paul N. Schofield,Carmel E. Mothersill
Publisher : CRC Press
Page : 227 pages
File Size : 40,9 Mb
Release : 2023-10-17
Category : Science
ISBN : 9781000985627

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Environmental Radiobiology by Paul N. Schofield,Carmel E. Mothersill Pdf

This book focuses on the impacts of anthropogenic radiation on wildlife and ecosystems and provides an in-depth look at the approaches and available tools we can use to gain information about biological effects of radiation in the environment. The nuclear accidents in Chornobyl in 1986 and Fukushima in 2011 focussed the attention of the world on the vulnerability of ecosystems to radiation. In Chornobyl, there still remains an exclusion zone where levels are considered to be too high for people and impacts on terrestrial and aquatic ecosystems can still be measured 35 years later. In the area impacted by the Fukushima disaster, intense remediation is still under way at tremendous cost and causing widespread disruption to the environment. That accident impacted the terrestrial and marine ecosystems. In both accidents it became obvious that a radiation protection framework focussing on protection of “humans” (a single species) and using evacuation as a key strategy, was not sufficient to protect the natural environment. The complexity of ecosystems makes developing a protection framework very challenging but in order to even start the process it is vital to gather information about likely impacts of low dose exposures on wildlife and to develop monitoring tools to measure changes over time. This book contains reviews and original research aimed at filling our knowledge gaps about these important areas. Environmental Radiobiology will be a key resource for academics, researchers, and advanced students of Radiobiology, Radioecology, Biology, Ecology, Biomedicine and Research Methods. The chapters included in this book were originally published as a special issue of International Journal of Radiation Biology.

Author : 0 McCarthy
Publisher : CRC Press
Page : 467 pages
File Size : 46,8 Mb
Release : 2018-01-18
Category : Science
ISBN : 9781351078719

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Biomarkers of Environmental Contamination by 0 McCarthy Pdf

How can biological markers help assess and predict human health risks? Find out the answers to this question and others in this timely new book examining the use of biological markers in animals and plants for evaluating the ecological and health effects of environmental contamination. The book explains the concept of environmental sentinels, presents example of field studies and discusses the utility of biomarkers within a risk analysis paradigm. Anyone who needs to know how to assess and predict environmental contamination should consider this book essential reading.

Author : Massimiliano Vasile,Domenico Quagliarella
Publisher : Springer Nature
Page : 448 pages
File Size : 54,8 Mb
Release : 2022-01-27
Category : Technology & Engineering
ISBN : 9783030805425

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Advances in Uncertainty Quantification and Optimization Under Uncertainty with Aerospace Applications by Massimiliano Vasile,Domenico Quagliarella Pdf

The 2020 International Conference on Uncertainty Quantification & Optimization gathered together internationally renowned researchers in the fields of optimization and uncertainty quantification. The resulting proceedings cover all related aspects of computational uncertainty management and optimization, with particular emphasis on aerospace engineering problems. The book contributions are organized under four major themes: Applications of Uncertainty in Aerospace & Engineering Imprecise Probability, Theory and Applications Robust and Reliability-Based Design Optimisation in Aerospace Engineering Uncertainty Quantification, Identification and Calibration in Aerospace Models This proceedings volume is useful across disciplines, as it brings the expertise of theoretical and application researchers together in a unified framework.

Author : World Health Organization
Publisher : World Health Organization
Page : 111 pages
File Size : 47,7 Mb
Release : 2009
Category : Medical
ISBN : 9789241547673

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WHO Handbook on Indoor Radon by World Health Organization Pdf

This handbook focuses on residential radon exposure from a public health point of view and provides detailed recommendations on reducing health risks from radon and sound policy options for preventing and mitigating radon exposure. The material in the handbook reflects the epidemiological evidence that indoor radon exposure is responsible for a substantial number of lung cancers in the general population. Information is provided on the selection of devices to measure radon levels and on procedures for the reliable measurement of these levels. Discussed also are control options for radon in new dwellings, radon reduction in existing dwellings as well as assessment of the costs and benefits of different radon prevention and remedial actions. Also covered are radon risk communication strategies and organization of national radon programs.--Publisher's description.

Author : Suzanne H. Reuben
Publisher : DIANE Publishing
Page : 240 pages
File Size : 47,7 Mb
Release : 2010-10
Category : Health & Fitness
ISBN : 9781437934212

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Reducing Environmental Cancer Risk by Suzanne H. Reuben Pdf

Though overall cancer incidence and mortality have continued to decline in recent years, cancer continues to devastate the lives of far too many Americans. In 2009 alone, 1.5 million American men, women, and children were diagnosed with cancer, and 562,000 died from the disease. There is a growing body of evidence linking environmental exposures to cancer. The Pres. Cancer Panel dedicated its 2008¿2009 activities to examining the impact of environmental factors on cancer risk. The Panel considered industrial, occupational, and agricultural exposures as well as exposures related to medical practice, military activities, modern lifestyles, and natural sources. This report presents the Panel¿s recommend. to mitigate or eliminate these barriers. Illus.