Biomaterials And Devices For The Circulatory System

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Biomaterials and Devices for the Circulatory System

Terence Gourlay,Richard A Black
Biomaterials and Devices for the Circulatory System Book PDF

Author : Terence Gourlay,Richard A Black
Publisher : Elsevier
Page : 400 pages
File Size : 54,9 Mb
Release : 2010-10-28
Category : Medical
ISBN : 9780857090553

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Biomaterials and Devices for the Circulatory System by Terence Gourlay,Richard A Black Pdf

Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Bioengineering and Biomaterials in Ventricular Assist Devices

Eduardo Guy Perpétuo Bock
Bioengineering and Biomaterials in Ventricular Assist Devices Book PDF

Author : Eduardo Guy Perpétuo Bock
Publisher : CRC Press
Page : 363 pages
File Size : 45,8 Mb
Release : 2021-10-07
Category : Medical
ISBN : 9781000462852

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Bioengineering and Biomaterials in Ventricular Assist Devices by Eduardo Guy Perpétuo Bock Pdf

Often associated with artificial hearts, ventricular assist devices (VADs) are blood pumps that can provide circulatory assistance to the left ventricle, the right ventricle, or both. Bioengineering and Biomaterials in Ventricular Assist Devices reviews constructive details of VADs and the biomaterials used in their development and support. FEATURES Establishes an area of intersection between engineering and medicine Shows process development from mechanical design to automation and control Discusses biofunctional materials, tribology in ceramic biomaterials, biosensors, and surface engineering and blood This text is aimed at advanced students, researchers, and practicing engineers conducting work on VADs and will be of interest to a broad interdisciplinary group, including bioengineers, materials engineers, chemical engineers, mechanical engineers, and electrical engineers.

The Artificial Heart

Institute of Medicine,Division of Health Care Services,Committee to Evaluate the Artificial Heart Program of the National Heart, Lung, and Blood Institute
The Artificial Heart Book PDF

Author : Institute of Medicine,Division of Health Care Services,Committee to Evaluate the Artificial Heart Program of the National Heart, Lung, and Blood Institute
Publisher : National Academies Press
Page : 313 pages
File Size : 46,9 Mb
Release : 1991-02-01
Category : Medical
ISBN : 9780309045322

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The Artificial Heart by Institute of Medicine,Division of Health Care Services,Committee to Evaluate the Artificial Heart Program of the National Heart, Lung, and Blood Institute Pdf

A significant medical event is expected in 1992: the first human use of a fully implantable, long-term cardiac assist device. This timely volume reviews the artificial heart program-and in particular, the National Institutes of Health's major investment-raising important questions. The volume includes: Consideration of the artificial heart versus heart transplantation and other approaches to treating end-stage heart disease, keeping in mind the different outcomes and costs of these treatments. A look at human issues, including the number of people who may require the artificial heart, patient quality of life, and other ethical and societal questions. Examination of how this technology's use can be targeted most appropriately. Attention to achieving access to this technology for all those who can benefit from it. The committee also offers three mechanisms to aid in allocating research and development funds.

Flow Dynamics and Tissue Engineering of Blood Vessels

Arindam Bit
Flow Dynamics and Tissue Engineering of Blood Vessels Book PDF

Author : Arindam Bit
Publisher : Myprint
Page : 316 pages
File Size : 52,5 Mb
Release : 2020-12
Category : Electronic
ISBN : 0750320893

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Flow Dynamics and Tissue Engineering of Blood Vessels by Arindam Bit Pdf

Flow Dynamics and Tissue Engineering of Blood Vessels explores the physical phenomena of vessel compliance and its influence on blood flow dynamics, as well as the modification of flow structures in the presence of diseases within the vessel wall or diseased blood content. This volume also illustrates the progress of tissue engineering for the intervention of re-engineered blood vessels. Blood vessel organoid models, their controlling aspects, and blood vessels based on microfluidic platforms are illustrated following on from the understanding of flow physics of blood on a similar platform. The purpose of this book is to provide an overview of regenerative medicine and fluid mechanics principles for the management of clinically diseased blood vessels. Authors discuss tissue engineering aspects and computational fluid mechanical principles, and how they can be used to understand the state of blood vessels in diseased conditions. Key Features Computational and experimental fluid dynamics principles have been used to explore the modelling of diseased blood vessels Principles of fluid dynamics and tissue engineering are used to propose innovative designs of bioreactors for blood vessel regeneration Offers experimental analytical studies of blood flow in vessels with pathological conditions Controlling aspects of various parameters while developing blood-vessel bioreactors and organoid models are presented critically, and optimization techniques for these parameters are also provided

Minimized Cardiopulmonary Bypass Techniques and Technologies

Terence Gourlay,Serdar Gunaydin
Minimized Cardiopulmonary Bypass Techniques and Technologies Book PDF

Author : Terence Gourlay,Serdar Gunaydin
Publisher : Elsevier
Page : 272 pages
File Size : 43,6 Mb
Release : 2012-04-19
Category : Medical
ISBN : 9780857096029

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Minimized Cardiopulmonary Bypass Techniques and Technologies by Terence Gourlay,Serdar Gunaydin Pdf

Traditional cardiopulmonary bypass (CPB) techniques have suffered from a number of disadvantages including haemodilution, inflammation and post-operative bleeding. Minimised cardiopulmonary bypass techniques use developments in perfusion technology to significantly reduce foreign surface-blood interactions to make bypass simpler and safer. This important book reviews key developments and issues relating to this promising technology. Part one covers the broad range of CPB pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces, optimal haemodilution levels, and the important issue of CPB-induced systemic inflammatory response syndrome. Part two focuses on the issues of the new equipment developed for mini-CPB, optimal myocardial protection protocols and CPB perfusate options. Part three discusses clinical issues, including patient selection, coronary and valve surgery protocols and, among others, paediatric patients. With its distinguished editors and international team of expert contributors, Minimized cardiopulmonary bypass techniques and technologies is a valuable reference for cardiac surgery teams and those researching this important technology. Covers a broad range of cardiopulmonary bypass (CPB) pathophysiology, including anticoagulant protocols, the impact of CPB circuit surfaces and optimal haemodilution levels Focuses on new equipment specially developed for minimized-CPB and myocardial protection protocols Discusses clinical issues, including patient selection

Functionalised Cardiovascular Stents

Gerard Wall,Halina Podbielska,Magdalena Wawrzynska
Functionalised Cardiovascular Stents Book PDF

Author : Gerard Wall,Halina Podbielska,Magdalena Wawrzynska
Publisher : Woodhead Publishing
Page : 368 pages
File Size : 51,7 Mb
Release : 2018-02-06
Category : Medical
ISBN : 9780081004982

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Functionalised Cardiovascular Stents by Gerard Wall,Halina Podbielska,Magdalena Wawrzynska Pdf

Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo. Provides a specific focus on cardiovascular stents Includes a range of topics covering the fundamentals, surface modification and biofunctionalization Provides essential knowledge for researchers on advances in the field

Applications of Polyurethanes in Medical Devices

Ajay Padsalgikar
Applications of Polyurethanes in Medical Devices Book PDF

Author : Ajay Padsalgikar
Publisher : William Andrew
Page : 283 pages
File Size : 51,6 Mb
Release : 2022-05-19
Category : Technology & Engineering
ISBN : 9780128231685

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Applications of Polyurethanes in Medical Devices by Ajay Padsalgikar Pdf

Applications of Polyurethanes in Medical Devices provides detailed coverage of polyurethane (PU) chemistry, processing and preparation for performant medical devices. Polyurethanes have found many uses in medical applications, due to their biocompatibility, biostability, physical properties, surface polarity, and the ability to suit the field of application. This book enables the reader to understand polyurethane and how this valuable material can be used in medical devices. Sections cover the chemistry, structure, and properties of polyurethane, with in-depth sections examining raw materials, reaction chemistry, synthesis techniques, reaction kinetics, material microstructure, and structure-property relationships. Subsequent chapters demonstrate how polyurethane can be utilized in medical device applications, examining biological properties, rheology and processing before methodical coverage explains how polyurethane may be used for each category of medical device. Finally, future directions, and safety and environmental aspects, are covered. Bridges the gap between polyurethane chemistry, processing and preparation for cutting-edge medical device applications Includes in-depth coverage of polyurethane, covering raw materials, chemistry, synthesis techniques, reaction kinetics, properties and microstructural analysis Takes a valuable and practical approach, addressing manufacturing issues and using testing and modeling to solve problems encountered in processing

Plastics in Medical Devices for Cardiovascular Applications

Ajay Padsalgikar
Plastics in Medical Devices for Cardiovascular Applications Book PDF

Author : Ajay Padsalgikar
Publisher : William Andrew
Page : 196 pages
File Size : 43,9 Mb
Release : 2017-02-01
Category : Technology & Engineering
ISBN : 9780323371223

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Plastics in Medical Devices for Cardiovascular Applications by Ajay Padsalgikar Pdf

Plastics in Medical Devices for Cardiovascular Applications enables designers of new cardiovascular medical devices to make decisions about the kind of plastics that can go into the manufacture of their device by explaining the property requirements of various applications in this area, including artificial valves, lead insulation, balloons, vascular grafts, and more. Enables designers to improve device performance and remain compliant with regulations by selecting the best material for each application Presents a range of applications, including artificial valves, stents, and vascular grafts Explains which materials can be used for each application, and why each is appropriate, thus assisting in the design of better tools and processes

Biomaterials, Artificial Organs and Tissue Engineering

L Hench,J. Jones
Biomaterials Artificial Organs and Tissue Engineering Book PDF

Author : L Hench,J. Jones
Publisher : Elsevier
Page : 298 pages
File Size : 42,5 Mb
Release : 2005-09-27
Category : Science
ISBN : 9781845690861

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Biomaterials, Artificial Organs and Tissue Engineering by L Hench,J. Jones Pdf

Maintaining quality of life in an ageing population is one of the great challenges of the 21st Century. This book summarises how this challenge is being met by multi-disciplinary developments of specialty biomaterials, devices, artificial organs and in-vitro growth of human cells as tissue engineered constructs. Biomaterials, Artificial Organs and Tissue Engineering is intended for use as a textbook in a one semester course for upper level BS, MS and Meng students. The 25 chapters are organized in five parts: Part one provides an introduction to living and man-made materials for the non-specialist; Part two is an overview of clinical applications of various biomaterials and devices; Part three summarises the bioengineering principles, materials and designs used in artificial organs; Part four presents the concepts, cell techniques, scaffold materials and applications of tissue engineering; Part five provides an overview of the complex socio-economic factors involved in technology based healthcare, including regulatory controls, technology transfer processes and ethical issues. Comprehensive introduction to living and man-made materials Looks at clinical applications of various biomaterials and devices Bioengineering principles, materials and designs used in artificial organs are summarised

Inhaler Devices

Polina Prokopovich
Inhaler Devices Book PDF

Author : Polina Prokopovich
Publisher : Elsevier
Page : 192 pages
File Size : 47,9 Mb
Release : 2013-04-23
Category : Technology & Engineering
ISBN : 9780857098696

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Inhaler Devices by Polina Prokopovich Pdf

Given their direct impact on the health and quality of life for millions, inhalers represent a major turning point in the history of modern medicine. Inhaler devices: Fundamentals, design and drug delivery provides readers with an introduction to the fundamentals of inhaler technology, with a comprehensive discussion of the history of inhalers as well as a discussion on current research and development. Part one discusses the fundamentals and development of inhaler devices as well as drug formulations for inhalers. The treatment of asthma is also discussed. Part two reviews recent developments in drug formulation and nanotechnology for inhaler devices, emerging inhaler technology and possible future trends. Inhaler devices: Fundamentals, design and drug delivery is an essential design guide for good industrial practice, and will be an invaluable resource for those researching and treating conditions such as asthma; and those developing and manufacturing inhalation devices. Introduces the fundamentals of inhaler technology Discusses the history of inhalers as well as current research and development as well as possible future trends Considers the development of inhaler devices, drug formulations and discusses the treatment of asthma

Medical Devices

Seeram Ramakrishna,Lingling Tian,Charlene Wang,Susan Liao,Wee Eong Teo
Medical Devices Book PDF

Author : Seeram Ramakrishna,Lingling Tian,Charlene Wang,Susan Liao,Wee Eong Teo
Publisher : Woodhead Publishing
Page : 256 pages
File Size : 45,7 Mb
Release : 2015-08-18
Category : Medical
ISBN : 9780081002919

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Medical Devices by Seeram Ramakrishna,Lingling Tian,Charlene Wang,Susan Liao,Wee Eong Teo Pdf

Medical Devices and Regulations: Standards and Practices will shed light on the importance of regulations and standards among all stakeholders, bioengineering designers, biomaterial scientists and researchers to enable development of future medical devices. Based on the authors’ practical experience, this book provides a concise, practical guide on key issues and processes in developing new medical devices to meet international regulatory requirements and standards. Provides readers with a global perspective on medical device regulations Concise and comprehensive information on how to design medical devices to ensure they meet regulations and standards Includes a useful case study demonstrating the design and approval process

Microfluidic Devices for Biomedical Applications

Xiujun James Li,Yu Zhou
Microfluidic Devices for Biomedical Applications Book PDF

Author : Xiujun James Li,Yu Zhou
Publisher : Elsevier
Page : 676 pages
File Size : 47,7 Mb
Release : 2013-10-31
Category : Technology & Engineering
ISBN : 9780857097040

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Microfluidic Devices for Biomedical Applications by Xiujun James Li,Yu Zhou Pdf

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering

Biocompatibility and Performance of Medical Devices

Jean-Pierre Boutrand
Biocompatibility and Performance of Medical Devices Book PDF

Author : Jean-Pierre Boutrand
Publisher : Elsevier
Page : 544 pages
File Size : 41,9 Mb
Release : 2012-10-26
Category : Medical
ISBN : 9780857096456

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Biocompatibility and Performance of Medical Devices by Jean-Pierre Boutrand Pdf

Implant and device manufacturers are increasingly facing the challenge of proving that their products are safe and biocompatible, and that they will perform as expected. Biocompatibility and performance of medical devices provides an essential guide to the performance analysis of these vital devices. Part one introduces the key concepts and challenges faced in relation to biocompatibility in medical devices, with consideration of biological safety evaluation planning and biomechanical and biochemical compatibility in innovative biomaterials. Part two goes on to discuss the evaluation and characterisation of biocompatibility in medical devices. Topics covered include material and chemical characterisation, allowable limits for toxic leachables, in vivo and in vitro testing and blood compatibility assessment. Testing and interpreting medical device performance is the focus of part three, with chapters describing preclinical performance studies for bone, dental and soft tissue implants, and mechanical testing of soft and hard tissue implants. Part four provides information on the regulation of medical devices in the European Union, Japan and China, and the book concludes with part five, a review of histopathology principles for biocompatibility and performance studies. With its distinguished editor and international team of expert contributors, Biocompatibility and performance of medical devices is a vital tool for all those involved in the research, design, production and application of medical devices, including research directors, production companies and medical regulatory agencies, as well as industry professionals and academics. Examines the key concepts and challenges faced in relation to biocompatibility in medical devices Discusses evaluation and characterisation issues, including material and chemical characterization, allowable limits for toxic leachables, in vivo and in vitro testing, and blood compatibility assessment Delivers a comprehensive overview of testing and interpreting medical device performance

Modelling Degradation of Bioresorbable Polymeric Medical Devices

J Pan
Modelling Degradation of Bioresorbable Polymeric Medical Devices Book PDF

Author : J Pan
Publisher : Elsevier
Page : 260 pages
File Size : 43,7 Mb
Release : 2014-10-24
Category : Technology & Engineering
ISBN : 9781782420255

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Modelling Degradation of Bioresorbable Polymeric Medical Devices by J Pan Pdf

The use of bioresorbable polymers in stents, fixation devices and tissue engineering is revolutionising medicine. Both industry and academic researchers are interested in using computer modelling to replace some experiments which are costly and time consuming. This book provides readers with a comprehensive review of modelling polymers and polymeric medical devices as an alternative to practical experiments. Chapters in part one provide readers with an overview of the fundamentals of biodegradation. Part two looks at a wide range of degradation theories for bioresorbable polymers and devices. The final set of chapters look at advances in modelling biodegradation of bioresorbable polymers. This book is an essential guide to those concerned with replacing tests and experiments with modelling. Provides a comprehensive mathematical framework for computer modelling of polymers and polymeric medical devices that can significantly reduce the number of experiments needed. Reviews the fundamental methods of modelling degradation, and applies these to particular materials including amorphous bioresorbable polyesters, semicrystalline biodegradable polyesters, and composite materials made of biodegradable polyesters and triclcium phosphates

Implantable Sensor Systems for Medical Applications

Andreas Inmann,Diana Hodgins
Implantable Sensor Systems for Medical Applications Book PDF

Author : Andreas Inmann,Diana Hodgins
Publisher : Elsevier
Page : 544 pages
File Size : 45,7 Mb
Release : 2013-01-02
Category : Science
ISBN : 9780857096289

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Implantable Sensor Systems for Medical Applications by Andreas Inmann,Diana Hodgins Pdf

Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications. Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants. With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies. Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applications Reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassembly Considers the challenges associated with implantable systems, including biocompatibility and sterilization