Biomaterials For Musculoskeletal Regeneration

Author : Bikramjit Basu,Sourabh Ghosh
Publisher : Springer
Page : 262 pages
File Size : 41,7 Mb
Release : 2016-11-01
Category : Technology & Engineering
ISBN : 9789811030178

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Biomaterials for Musculoskeletal Regeneration by Bikramjit Basu,Sourabh Ghosh Pdf

This book discusses a number of case studies to showcase the translation of research concepts to lab-scale materials development for biomedical applications. The book intends to motivate active researchers to develop new generation biomaterials. This book is meant for readers, who are already familiar with the broad area of biomaterials. The book introduces readers to the field of additive manufacturing of biomaterials and teaches them how to extend this innovative processing approach to a variety of biomaterials for musculoskeletal applications. It covers both in vitro and in vivo biocompatibility and toxicity assessment for a broad range of biomaterials in the context of bone tissue engineering. It works to sensitise researchers in the field of translational biomedical engineering on the importance of clinical trials and discusses the challenges ahead in this important field of research. This book will be useful to clinicians, professionals and researchers alike.

Author : Mehdi Razavi
Publisher : Academic Press
Page : 290 pages
File Size : 43,7 Mb
Release : 2020-05-09
Category : Science
ISBN : 9780128202630

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Nanoengineering in Musculoskeletal Regeneration by Mehdi Razavi Pdf

Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline—from biomedical discovery to clinical implementation—aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Provides broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration Offers useful guidance for physician-scientists with expertise in orthopedics, regenerative medicine, bioengineering, biomaterials, nanoengineering, stem cell biology, and chemistry Serves as a practical reference for many disciplines, including bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine, and nanomedicine

Author : William S. Pietrzak
Publisher : Springer Science & Business Media
Page : 649 pages
File Size : 55,7 Mb
Release : 2008-04-11
Category : Medical
ISBN : 9781597452397

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Musculoskeletal Tissue Regeneration by William S. Pietrzak Pdf

The repair of musculoskeletal tissue is a vital concern of all surgical specialties, orthopedics and related disciplines. Written by recognized experts, this book aims to provide both basic and advanced knowledge of the newer methodologies being developed and introduced to the clinical arena. A valuable resource for researchers, developers, and clinicians, the book presents a foundation to propel the technology and integration of the current state of knowledge into the 21st century.

Author : Justin Brown,Sangamesh Kumbar,Brittany Banik
Publisher : Academic Press
Page : 252 pages
File Size : 45,9 Mb
Release : 2016-11-03
Category : Technology & Engineering
ISBN : 9780128033999

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Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine by Justin Brown,Sangamesh Kumbar,Brittany Banik Pdf

Bio-Instructive Scaffolds for Musculoskeletal Tissue Engineering and Regenerative Medicine explores musculoskeletal tissue growth and development across populations, ranging from elite athletes to the elderly. The regeneration and reparation of musculoskeletal tissues present the unique challenges of requiring both the need to withstand distinct forces applied to the body and ability to support cell populations. The book is separated into sections based on tissue type, including bone, cartilage, ligament and tendon, muscle, and musculoskeletal tissue interfaces. Within each tissue type, the chapters are subcategorized into strategies focused on cells, hydrogels, polymers, and other materials (i.e. ceramics and metals) utilized in musculoskeletal tissue engineering applications. In each chapter, the relationships that exist amongst the strategy, stem cell differentiation and somatic cell specialization at the intracellular level are emphasized. Examples include intracellular signaling through growth factor delivery, geometry sensing of the surrounding network, and cell signaling that stems from altered population dynamics. Presents a self-contained work for the field of musculoskeletal tissue engineering and regenerative medicine Focuses on how materials of structures can be designed to be resistant while promoting viable grafts Contains major tissue types that are covered with a strategy for each material and structure

Author : Syam Nukavarapu,Joseph Freeman,Cato Laurencin
Publisher : Woodhead Publishing
Page : 463 pages
File Size : 46,8 Mb
Release : 2015-04-24
Category : Science
ISBN : 9781782423140

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Regenerative Engineering of Musculoskeletal Tissues and Interfaces by Syam Nukavarapu,Joseph Freeman,Cato Laurencin Pdf

Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation

Author : J. Miguel Oliveira,Rui L. Reis,Sandra Pina
Publisher : Elsevier
Page : 556 pages
File Size : 49,8 Mb
Release : 2023-11-28
Category : Science
ISBN : 9780323972628

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Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine by J. Miguel Oliveira,Rui L. Reis,Sandra Pina Pdf

Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health. Presents the fundamentals of the complex interplay of cells with biomaterials in musculoskeletal tissue engineering Includes coverage of stem cells and cell-based therapies, in vitro and in vivo models, nanotechnology, bioprinting, computational modeling, regulatory and clinical translation, and much more Written by global leaders in the field

Author : Huinan Liu
Publisher : Woodhead Publishing
Page : 406 pages
File Size : 50,7 Mb
Release : 2016-02-23
Category : Technology & Engineering
ISBN : 9781782424758

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Nanocomposites for Musculoskeletal Tissue Regeneration by Huinan Liu Pdf

Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass

Author : Yupeng Chen
Publisher : Elsevier
Page : 385 pages
File Size : 41,9 Mb
Release : 2021-11-04
Category : Technology & Engineering
ISBN : 9780128242100

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Musculoskeletal Tissue Engineering by Yupeng Chen Pdf

Musculoskeletal Tissue Engineering introduces the fundamental concepts and translational applications of musculoskeletal tissue engineering, in combination with emerging technologies and materials. Sections discuss Tissues and Technologies, covering a range of musculoskeletal tissues, including bone, cartilage, ligament and more. Each chapter in this section details core tissue engineering principles specific to each tissue type. Next, a Technologies section looks at the range of biomaterials used in musculoskeletal tissue engineering, focusing on biocompatibility of materials and interactions at the material-tissue interface. Other chapters cover nanotechnology, 3D printing, gene therapy, tissue chips, and more. This book offers an advanced reference text for researchers in biomedical engineering, materials science and regenerative medicine. Details various materials and cutting-edge technologies for musculoskeletal tissue engineering Covers a range of musculoskeletal tissues, including bone, cartilage, ligament, tendon, meniscus, and more Provides a balance between basic concepts and translational applications for a broad audience

Author : Farnaz Ghorbani,Chaozong Liu,Derek H. Rosenzweig,Megan Elin Cooke
Publisher : Frontiers Media SA
Page : 197 pages
File Size : 52,5 Mb
Release : 2022-04-25
Category : Science
ISBN : 9782889749898

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Biofabrication and Biopolymeric Materials Innovation for Musculoskeletal Tissue Regeneration by Farnaz Ghorbani,Chaozong Liu,Derek H. Rosenzweig,Megan Elin Cooke Pdf

Author : Martin J. Stoddart,April M. Craft,Girish Pattappa,Oliver F.W. Gardner
Publisher : Academic Press
Page : 270 pages
File Size : 46,7 Mb
Release : 2018-04-24
Category : Science
ISBN : 9780128115381

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Developmental Biology and Musculoskeletal Tissue Engineering by Martin J. Stoddart,April M. Craft,Girish Pattappa,Oliver F.W. Gardner Pdf

Developmental Biology and Musculoskeletal Tissue Engineering: Principles and Applications focuses on the regeneration of orthopedic tissue, drawing upon expertise from developmental biologists specializing in orthopedic tissues and tissue engineers who have used and applied developmental biology approaches. Musculoskeletal tissues have an inherently poor repair capacity, and thus biologically-based treatments that can recapitulate the native tissue properties are desirable. Cell- and tissue-based therapies are gaining ground, but basic principles still need to be addressed to ensure successful development of clinical treatments. Written as a source of information for practitioners and those with a nascent interest, it provides background information and state-of-the-art solutions and technologies. Recent developments in orthopedic tissue engineering have sought to recapitulate developmental processes for tissue repair and regeneration, and such developmental-biology based approaches are also likely to be extremely amenable for use with more primitive stem cells. Brings the fields of tissue engineering and developmental biology together to explore the potential for regenerative medicine-based research to contribute to enhanced clinical outcomes Initial chapters provide an outline of the development of the musculoskeletal system in general, and later chapters focus on specific tissues Addresses the effect of mechanical forces on the musculoskeletal system during development and the relevance of these processes to tissue engineering Discusses the role of genes in the development of musculoskeletal tissues and their potential use in tissue engineering Describes how developmental biology is being used to influence and guide tissue engineering approaches for cartilage, bone, disc, and tendon repair

Author : Sumit Murab
Publisher : Springer Nature
Page : 225 pages
File Size : 46,7 Mb
Release : 2024-07-03
Category : Electronic
ISBN : 9783031556531

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Drug Delivery Systems for Musculoskeletal Tissues by Sumit Murab Pdf

Author : Andrea Vernengo,Dmitriy Sheyn,Rahul Gawri,Mark Buckley
Publisher : Frontiers Media SA
Page : 407 pages
File Size : 51,9 Mb
Release : 2023-09-06
Category : Science
ISBN : 9782832533123

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Emerging technologies for musculoskeletal disease modeling and regenerative medicine by Andrea Vernengo,Dmitriy Sheyn,Rahul Gawri,Mark Buckley Pdf

Author : Alberto Gobbi,João Espregueira-Mendes,John G. Lane,Mustafa Karahan
Publisher : Springer
Page : 0 pages
File Size : 42,7 Mb
Release : 2018-08-03
Category : Medical
ISBN : 3662571846

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Bio-orthopaedics by Alberto Gobbi,João Espregueira-Mendes,John G. Lane,Mustafa Karahan Pdf

This book introduces the exciting field of orthobiology, which will usher in a new array of therapeutic approaches that stimulate the body’s natural resources to regenerate musculoskeletal tissues damaged by trauma or disease. The book addresses a range of key topics and discusses emerging approaches that promise to offer effective alternatives to traditional treatments for injuries to bone, cartilage, muscles, ligaments, and tendons. It explains in detail how a variety of innovative products, including biomaterials, growth factors, and autogenous cells, together provide the basis for the regeneration of these musculoskeletal structures and how recent scientific progress has created unique opportunities to address pathological situations that until recently have been treated with unsatisfactory results. The authors are experts from across the world who come together to provide a truly global overview. The book is published in collaboration with ISAKOS. It will be invaluable for all with an interest in this area of medicine, which has already attained huge popularity in Orthopaedics and Sports Medicine and has also attracted the attention of the lay public.

Author : Heung Jae Chun,Kwideok Park,Chun-Ho Kim,Gilson Khang
Publisher : Springer
Page : 537 pages
File Size : 41,5 Mb
Release : 2018-10-24
Category : Medical
ISBN : 9789811309472

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Novel Biomaterials for Regenerative Medicine by Heung Jae Chun,Kwideok Park,Chun-Ho Kim,Gilson Khang Pdf

This book explores in depth a wide range of new biomaterials that hold great promise for applications in regenerative medicine. The opening two sections are devoted to biomaterials designed to direct stem cell fate and regulate signaling pathways. Diverse novel functional biomaterials, including injectable nanocomposite hydrogels, electrosprayed nanoparticles, and waterborne polyurethane-based materials, are then discussed. The fourth section focuses on inorganic biomaterials, such as nanobioceramics, hydroxyapatite, and titanium dioxide. Finally, up-to-date information is provided on a wide range of smart natural biomaterials, ranging from silk fibroin-based scaffolds and collagen type I to chitosan, mussel-inspired biomaterials, and natural polymeric scaffolds. This is one of two books to be based on contributions from leading experts that were delivered at the 2018 Asia University Symposium on Biomedical Engineering in Seoul, Korea – the companion book examines in depth the latest enabling technologies for regenerative medicine.

Author : Jiang Chang,Xingdong Zhang,Kerong Dai
Publisher : Academic Press
Page : 252 pages
File Size : 54,9 Mb
Release : 2020-02-28
Category : Technology & Engineering
ISBN : 9780128135044

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Bioactive Materials for Bone Regeneration by Jiang Chang,Xingdong Zhang,Kerong Dai Pdf

Bioactive Materials for Bone Regeneration summarizes research advances on the topic, including sections on the characteristics of biomaterial-induced microenvironments, interactions of bioactive materials with stem cells and tissues, and the immunomodulatory microenvironment induced by biomaterials and its effects on osteogenesis. As the regeneration of large-size bone tissue defects represents a significant clinical challenge, this book demonstrates how new biomaterials with specific chemical and physical characteristics may interact with the host and create a unique micro-environment that actively facilitates stem cell differentiation along a specific lineage, thus stimulating tissue regeneration. Provides readers with the latest research developments in the fabrication techniques of bioactive materials for tissue regeneration and tissue engineering applications Presents the latest research advancements on how bioactive materials interact with the host and induce micro-environments for stem cell differentiation, immunomodulation and tissue regeneration Covers the methods, strategies, principle and mechanisms on constructing beneficial biomaterial microenvironments