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Author : Sumit Murab
Publisher : Springer Nature
Page : 225 pages
File Size : 42,6 Mb
Release : 2024-07-03
Category : Electronic
ISBN : 9783031556531
Author : National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Care Services,Committee on Identifying Disabling Medical Conditions Likely to Improve with Treatment
Publisher : National Academies Press
Page : 319 pages
File Size : 44,7 Mb
Release : 2020-07-12
Category : Medical
ISBN : 9780309670951
The Social Security Administration (SSA) administers two programs that provide disability benefits: the Social Security Disability Insurance (SSDI) program and the Supplemental Security Income (SSI) program. SSDI provides disability benefits to people (under the full retirement age) who are no longer able to work because of a disabling medical condition. SSI provides income assistance for disabled, blind, and aged people who have limited income and resources regardless of their prior participation in the labor force. Both programs share a common disability determination process administered by SSA and state agencies as well as a common definition of disability for adults: "the inability to engage in any substantial gainful activity by reason of any medically determinable physical or mental impairment which can be expected to result in death or which has lasted or can be expected to last for a continuous period of not less than 12 months." Disabled workers might receive either SSDI benefits or SSI payments, or both, depending on their recent work history and current income and assets. Disabled workers might also receive benefits from other public programs such as workers' compensation, which insures against work-related illness or injuries occurring on the job, but those other programs have their own definitions and eligibility criteria. Selected Health Conditions and Likelihood of Improvement with Treatment identifies and defines the professionally accepted, standard measurements of outcomes improvement for medical conditions. This report also identifies specific, long-lasting medical conditions for adults in the categories of mental health disorders, cancers, and musculoskeletal disorders. Specifically, these conditions are disabling for a length of time, but typically don't result in permanently disabling limitations; are responsive to treatment; and after a specific length of time of treatment, improve to the point at which the conditions are no longer disabling.
Author : Dr. Sandip G. Babadhe
Publisher : Pencil
Page : 93 pages
File Size : 55,9 Mb
Release : 2024-05-26
Category : Juvenile Nonfiction
ISBN : 9789362632128
Implantable Drug Delivery Systems: Design, Applications, and Future Perspectives" by Dr. Sandip G. Badadhe offers a comprehensive overview of implantable drug delivery, covering design, materials, applications, challenges, and future prospects. It caters to researchers, healthcare professionals, and students, providing insights into various types of systems, materials used, and practical applications. With real-world case studies and recommendations for future research, it serves as a valuable resource in advancing this innovative field.
Author : Mehdi Razavi
Publisher : Academic Press
Page : 290 pages
File Size : 54,7 Mb
Release : 2020-05-22
Category : Science
ISBN : 9780128202623
Nanoengineering in Musculoskeletal Regeneration provides the reader an updated summary of the therapeutic pipeline-from biomedical discovery to clinical implementation-aimed at improving treatments for patients with conditions of the muscles, tendons, cartilage, meniscus, and bone. Regenerative medicine focuses on using stem cell biology to advance medical therapies for devastating disorders. This text presents novel, significant, and interdisciplinary theoretical and experimental results related to nanoscience and nanotechnology in musculoskeletal regeneration. Content includes basic, translational, and clinical research addressing musculoskeletal repair and regeneration for the treatment of diseases and injuries of the skeleton and its associated tissues. Musculoskeletal degeneration and complications from injuries have become more prevalent as people live longer and increasingly participate in rigorous athletic and recreational activities. Additionally, defects in skeletal tissues may immobilize people and cause inflammation and pain. Musculoskeletal regeneration research provides solutions to repair, restore, or replace skeletal elements and associated tissues that are affected by acute injury, chronic degeneration, genetic dysfunction, and cancer-related defects. The goal of musculoskeletal regeneration medicine research is to improve quality of life and outcomes for people with musculoskeletal injury or degradation. Provides broad coverage in all research areas focused on the applications of nanotechnology in musculoskeletal regeneration Offers useful guidance for physician-scientists with expertise in orthopedics, regenerative medicine, bioengineering, biomaterials, nanoengineering, stem cell biology, and chemistry Serves as a practical reference for many disciplines, including bioengineering, biomaterials, tissue engineering, regenerative medicine, musculoskeletal regenerative medicine, and nanomedicine
Author : Abraham J. Domb,Wahid Khan
Publisher : Springer Science & Business Media
Page : 700 pages
File Size : 42,9 Mb
Release : 2014-02-17
Category : Medical
ISBN : 9781461494348
The concept of focal controlled drug delivery has been applied for treating illnesses that are localized to a certain tissue or organ. These delivery systems are applied directly to the diseased site and deliver a desired dose for an extended time period while minimizing systemic distribution of toxic drug. Controlled drug delivery systems have been focused on oral extended release formulations and on systemic delivery of small drugs and peptides. Despite the upsurge of interest in focal targeted drug delivery, there is currently no single reference text on the subject. By comparison, there are numerous authored and edited books on oral, systemic and transdermal drug delivery or books on biodegradable polymers as drug carriers. Thus, the aim of Focal Drug Delivery is to bring together leading experts and researchers in the field to provide an authoritative account of the essential pharmaceutical, technological, physiological and biological sciences underpinning the topic. In addition, the book will review advances in treatment options for diseases localized at a certain tissue or organ.
Author : Huinan Liu
Publisher : Woodhead Publishing
Page : 406 pages
File Size : 55,8 Mb
Release : 2016-02-23
Category : Technology & Engineering
ISBN : 9781782424758
Nanocomposites for Musculoskeletal Tissue Regeneration discusses the advanced biomaterials scientists are exploring for use as tools to mimic the structure of musculoskeletal tissues. Bone and other musculoskeletal tissues naturally have a nanocomposite structure, therefore nanocomposites are ideally suited as a material for replacing and regenerating these natural tissues. In addition, biological properties such as biointegration and the ability to tailor and dope the materials make them highly desirable for musculoskeletal tissue regeneration. Provides a comprehensive discussion on the design and advancements made in the use of nanocomposites for musculoskeletal tissue regeneration Presents an In-depth coverage of material properties Includes discussions on polymers, ceramics, and glass
Author : J. Miguel Oliveira,Rui L. Reis,Sandra Pina
Publisher : Elsevier
Page : 556 pages
File Size : 51,8 Mb
Release : 2023-11-28
Category : Science
ISBN : 9780323972628
Multiscale Cell-Biomaterials Interplay in Musculoskeletal Tissue Engineering and Regenerative Medicine addresses the key concepts involved in the interactions between cells and biomaterials in the musculoskeletal tissue engineering and regenerative medicine field. The updated developments and challenges of the mechanisms/mechanobiology and structure-function properties of those interactions, as well as emerging technologies underlying tissue-engineered scaffolding, are carefully discussed. Lastly, cell engineering and cell-based therapies, growth factors/drugs properties, vascularization, immunomodulation are also outlined. Given the large number of musculoskeletal disorders and related injuries that can affect muscles, bones and joints and lead to severe complications of the neuromuscular system, it is imperative to develop new treatment strategies to delay or repair associated diseases and to promote optimal long-term health. Presents the fundamentals of the complex interplay of cells with biomaterials in musculoskeletal tissue engineering Includes coverage of stem cells and cell-based therapies, in vitro and in vivo models, nanotechnology, bioprinting, computational modeling, regulatory and clinical translation, and much more Written by global leaders in the field
Author : Yupeng Chen
Publisher : Elsevier
Page : 385 pages
File Size : 55,7 Mb
Release : 2021-11-04
Category : Technology & Engineering
ISBN : 9780128242100
Musculoskeletal Tissue Engineering introduces the fundamental concepts and translational applications of musculoskeletal tissue engineering, in combination with emerging technologies and materials. Sections discuss Tissues and Technologies, covering a range of musculoskeletal tissues, including bone, cartilage, ligament and more. Each chapter in this section details core tissue engineering principles specific to each tissue type. Next, a Technologies section looks at the range of biomaterials used in musculoskeletal tissue engineering, focusing on biocompatibility of materials and interactions at the material-tissue interface. Other chapters cover nanotechnology, 3D printing, gene therapy, tissue chips, and more. This book offers an advanced reference text for researchers in biomedical engineering, materials science and regenerative medicine. Details various materials and cutting-edge technologies for musculoskeletal tissue engineering Covers a range of musculoskeletal tissues, including bone, cartilage, ligament, tendon, meniscus, and more Provides a balance between basic concepts and translational applications for a broad audience
Author : Rajakumari Rajendran,Hanna J. Maria,Sabu Thomas,Nandakumar Kalarikkal
Publisher : CRC Press
Page : 606 pages
File Size : 41,8 Mb
Release : 2022-03-10
Category : Science
ISBN : 9781000369496
With contributions from leading researchers in the nanomedicine field from industry, academia, and government and private research institutions across the globe, the volume provides an up-to-date report on topical issues in nano-drug delivery and nanotechnological approaches to tissue engineering. The volume offers research on a variety of diverse nano-based drug delivery systems along with discussions of their efficacy, safety, toxicology, and applications for different purposes. Focusing on nanotechnology approaches to tissue engineering, this volume considers the use of hydrogel systems, nanoceria and micro- and nano-structured biomaterials for bone tissue engineering, mesenchymal stem cells, and more.
Author : Manuel Palencia,Tulio A. Lerma,Viviana Garcés,Mayra A. Mora,Jina M. Martínez,Sixta L. Palencia
Publisher : Elsevier
Page : 468 pages
File Size : 46,8 Mb
Release : 2021-07-25
Category : Science
ISBN : 9780128218549
There is a growing demand for strategies to address the impact of polymers and plastics in ecosystems. The principles of green chemistry offer a good source of such strategies. Ecofriendly Functional Polymers: An Approach from Application-Targeted Green Chemistry provides a holistic overview of polymer chemistry, development, and applications in the context of these sustainability-driven principles. It encourages researchers to consider the principles of green chemistry, environmental impacts, and end-user needs as integral aspects for consideration at the earliest stages of any design process, and draws together key aspects of polymer chemistry, organic synthesis, experimental design, and applications in a single volume. Beginning with an authoritative guide to fundamental polymer chemistry and its impact in the current environmental context, the book then discusses a range of key theoretical and experimental aspects of designing eco-friendly functional polymers. Applications of ecofriendly functional polymers across an entire range of fields are discussed, and a selection of case studies highlights the implementation of theoretical and experimental information to address a broad selection of issues. Highlights the physicochemical principles of green chemistry and the development of biodegradable and recyclable polymers in this context Compiles key information connecting structural features with properties, experimental strategies, and appropriate applications into a single volume Discusses requirements and applications across a broad range of fields, supported by practical examples
Author : Syam Nukavarapu,Joseph Freeman,Cato Laurencin
Publisher : Woodhead Publishing
Page : 463 pages
File Size : 51,6 Mb
Release : 2015-04-24
Category : Science
ISBN : 9781782423140
Repair and regeneration of musculoskeletal tissues is generating substantial interest within the biomedical community. Consequently, these are the most researched tissues from the regeneration point of view. Regenerative Engineering of Musculoskeletal Tissues and Interfaces presents information on the fundamentals, progress and recent developments related to the repair and regeneration of musculoskeletal tissues and interfaces. This comprehensive review looks at individual tissues as well as tissue interfaces. Early chapters cover various fundamentals of biomaterials and scaffolds, types of cells, growth factors, and mechanical forces, moving on to discuss tissue-engineering strategies for bone, tendon, ligament, cartilage, meniscus, and muscle, as well as progress and advances in tissue vascularization and nerve innervation of the individual tissues. Final chapters present information on musculoskeletal tissue interfaces. Comprehensive review of the repair and regeneration of musculoskeletal individual tissues and tissue interfaces Presents recent developments, fundamentals and progress in the field of engineering tissues Reviews progress and advances in tissue vascularization and innervation
Author : Mohamed A. Elsawy
Publisher : Springer Nature
Page : 556 pages
File Size : 53,6 Mb
Release : 2023-08-28
Category : Science
ISBN : 9783031293603
Molecular self-assembly has been exploited by nature for developing the higher functional macromolecular structures of both the genome and proteome. Inspired by nature, there has been a surge of research, in the last two decades, for the molecular engineering of peptide-based self-assembling nanostructures, adopting the bottom-up design approach. This book gives the reader an overview on the design rules for de novo self-assembling peptide and reviews the diverse range of bioinspired peptide nanostructures such as β-sheet and β-hairpin, α-helical and coiled coil, self-assembling short peptides and peptidomimetics, collagen-based and elastin-like peptides, silk peptides, peptide amphiphiles, peptides co-polymers and others. The book also covers the wide variety of responsive and functional biomaterials that have been innovated based on those nanostructures for various applications ranging from tissue engineering, therapeutics and drug delivery to antimicrobial nanomaterials and biosensors. Finally, the book also discusses the peptide bionanomaterials global market and the future of the emerging industry. Chapter “Characterization of Peptide-Based Nanomaterials” is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Author : Nirmal Shah
Publisher : Springer Nature
Page : 483 pages
File Size : 53,9 Mb
Release : 2021-01-22
Category : Medical
ISBN : 9789813344976
A suitable drug delivery system is an essential element in achieving efficient therapeutic responses of drug molecules. With this desirability in mind, the book unites different techniques through which extremely small-sized particles can be utilized as a successful carrier for curing chronic as well as life-threatening diseased conditions. This is a highly informative and prudently organized book, providing scientific insight for readers with an interest in nanotechnology. Beginning with an overview of nanocarriers, the book impetuses on to explore other essential ways through which these carriers can be employed for drug delivery to varieties of administrative routes. This book discusses the functional and significant features of nanotechnology in terms of Lymphatic and other drug targeting deliveries. The book is presenting depth acquaintance for various vesicular and particulate nano-drug delivery carriers, utilized successfully in Pharmaceutical as well as in Cosmeceutical industries along with brief information on their related toxicities. In addition, the work also explores the potential applications of nanocarriers in biotechnology sciences for the prompt and safe delivery of nucleic acid, protein, and peptide-based drugs. An exclusive section in the book illuminates the prominence and competent applicability of nanotechnology in the treatment of oral cancer. The persistence of this book is to provide basic to advanced information for different novel carriers which are under scale-up consideration for the extensive commercialization. The book also includes recent discoveries and the latest patents of such nanocarriers. The cutting-edge evidence of these nanocarriers available in this book is beneficial to students, research scholars, and fellows for promoting their advanced research.
Author : Ololade Olatunji
Publisher : Springer
Page : 372 pages
File Size : 51,8 Mb
Release : 2015-12-24
Category : Technology & Engineering
ISBN : 9783319264141
This book introduces the most recent innovations in natural polymer applications in the food, construction, electronics, biomedical, pharmaceutical, and engineering industries. The authors provide perspectives from their respective range of industries covering classification, extraction, modification, and application of natural polymers from various sources in nature. They discuss the techniques used in analysis of natural polymers in various systems incorporating natural polymers as well as their intrinsic properties.
Author : M. N. V. Ravi Kumar
Publisher : CRC Press
Page : 730 pages
File Size : 54,8 Mb
Release : 2017-03-27
Category : Medical
ISBN : 9789814669665
In the quest for innovative drug delivery systems attempting to meet the unmet needs in pharmaceutical space, research has taken a much more complicated path that poses a significant challenge for translation. Despite the progress made with novel materials, polyesters still remain at the helm of drug delivery technologies. This book provides a single source of reference of polyester drug delivery systems that covers a broad spectrum of materials design, manufacturing techniques, and applications.