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Nanoparticles for Biomedical Applications by Eun Ji Chung,Lorraine Leon,Carlos Rinaldi Pdf
Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications brings into one place information on the design and biomedical applications of different classes of nanoparticles. While aspects are dealt with in individual journal articles, there is not one source that covers this area comprehensively. This book fills this gap in the literature. Outlines an in-depth review of biomedical applications of a variety of nanoparticle classes Discusses the major techniques for designing nanoparticles for use in biomedicine Explores safety and regulatory aspects for the use of nanoparticles in biomedicine
Author : Alexandru Mihai Grumezescu Publisher : William Andrew Page : 530 pages File Size : 42,8 Mb Release : 2019-02-28 Category : Medical ISBN : 9780128166307
Biomedical Applications of Nanoparticles by Alexandru Mihai Grumezescu Pdf
Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles
Biomedical Application of Nanoparticles by Bertrand Henri Rihn Pdf
Biomedical Application of Nanoparticles explores nanoparticles, their chemical and physicals properties, and how they interact in biological systems with proteins, immune system and targeted cells. Risk assessment of nanoparticles for human is described, including: cellular paradigms, transcriptomics and toxicogenomics. Finally, the applications of nanoparticles in medicine and antioxidant regenerative therapeutics are presented in several chapters with emphasis on how nanoparticles enhance transport of drugs across biological membrane barriers and therefore may enhance drug bioavailability.
Application of Nanotechnology in Biomedical Sciences by Faheem A. Sheikh Pdf
This book highlights the wide applications of nanomaterials in healthcare and environmental remediation. Presenting nano-based materials that positively influence the growth and proliferation of cells present in soft and hard tissue and are used for the regeneration bone tissue and/or suppression of cancer cells, it also discusses the natural products that can be incorporated in nanofibers for the treatment of cancer. Further, it describes the use of blending and functionalization to produce chitosan nanofibers for biomedical applications, and reviews the role of plasma-enhanced gold nanoparticles in diagnostics and therapeutics. Lastly, the book also introduces various nanotechnology approaches for the removal of waste metabolites in drinking water, and explores the emerging applications of nanorobotics in medicine. Given its scope, this book is a valuable resource for scientists, clinicians, engineers and researchers aiming to gain a better understanding of the various applications of nanotechnology.
Green Nanoparticles by Jayanta Kumar Patra,Leonardo F. Fraceto,Gitishree Das,Estefânia Vangelie Ramos Campos Pdf
Nanotechnology is the application of science to control matter at the molecular level. It has become one of the most promising applied technologies in all areas of science. Nanoparticles have multi-functional properties and have created very interesting applications in various fields such as medicine, nutrition, bioenergy, agriculture and the environment. But the biogenic syntheses of monodispersed nanoparticles with specific sizes and shapes have been a challenge in biomaterial science. Nanoparticles are of great interest due to their extremely small size and large surface-to-volume ratio, which lead to both chemical and physical differences in their properties (e.g., mechanical properties, biological and sterical properties, catalytic activity, thermal and electrical conductivity, optical absorption and melting point) compared to bulk of the same chemical composition. Recently, however, synthesizing metal nanoparticles using green technology via microorganisms, plants, viruses, and so on, has been extensively studied and has become recognized as a green and efficient way for further exploiting biological systems as convenient nanofactories. Thus the biological synthesis of nanoparticles is increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. Today researchers are developing new techniques and materials using nanotechnology that may be suitable for plants to boost their native functions. Recently, biological nanoparticles were found to be more pharmacologically active than physico-chemically synthesized nanoparticles. Various applications of biosynthesized nanoparticles have been discovered, especially in the field of biomedical research, such as applications to specific delivery of drugs, use for tumor detection, angiogenesis, genetic disease and genetic disorder diagnosis, photoimaging, and photothermal therapy. Further, iron oxide nanoparticles have been applied to cancer therapy, hyperthermia, drug delivery, tissue repair, cell labeling, targeting and immunoassays, detoxification of biological fluids, magnetic resonance imaging, and magnetically responsive drug delivery therapy. Nanoparticle synthesis for plant byproducts for biomedical applications has vast potential. This book offers researchers in plant science and biomedicine the latest research and opportunity to develop new tools for the synthesis of environmentally friendly and cost-effective nanoparticles for applications in biomedicine as well as other various fields.
Biomedical Nanomaterials by Rostyslav S. Stoika Pdf
This book characterizes how to design and synthesize nanomaterials of an organic and mineral nature. The book also discusses the visualization of developed nanomaterials and their bio-applications, as well as describes the biomedical effects and environmental impact of nanomaterials. This is an ideal book for students studying biomedicine or the life sciences, as well as researchers and professionals in medicine, environmental protection, biotechnology, agriculture, and the food industry. More specifically, this book addresses the important nanomaterials and nanobiotechnologies that are used in those fields in biomedicine and life sciences.
Gold Nanoparticles in Biomedical Applications by Lev Dykman,Nikolai Khlebtsov Pdf
This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.
Smart Nanomaterials in Biomedical Applications by Jin-Chul Kim,Madhusudhan Alle,Azamal Husen Pdf
With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.
Biomedical Applications of Nanotechnology by Vinod Labhasetwar,Diandra L. Leslie-Pelecky Pdf
An overview of nanotechnology and its potential The field of nanotechnology is undergoing rapid developments on many fronts. This reference provides a comprehensive review of various nanotechnologies with a view to their biomedical applications. With chapters contributed by distinguished scientists from diverse disciplines, Biomedical Applications of Nanotechnology : Reviews recent advances in the designing of various nanotechnologies based on nucleic acids, polymers, biomaterials, and metals Discusses biomedical nanotechnology in areas such as drug and gene delivery Covers advanced aspects of imaging and diagnostics Includes a chapter on the issue of nanotoxicology Complete with figures and tables, this is a practical, hands-on reference book for researchers in pharmaceutical and biotech industries, biomedical engineers, pharmaceutical scientists, pharmacologists, and materials scientists as well as for the policymakers who need to understand the potential of nanotechnology. It is also an excellent resource book for graduate-level students in pharmaceutical sciences, biomedical engineering, and other fields in which nanotechnology is playing an increasingly important role.
Author : Bruno Sarmento,Jose Das Neves Publisher : William Andrew Page : 778 pages File Size : 54,9 Mb Release : 2018-03-01 Category : Science ISBN : 9780323508797
Biomedical Applications of Functionalized Nanomaterials by Bruno Sarmento,Jose Das Neves Pdf
Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications
Nanomaterials and Their Biomedical Applications by Tuhin Subhra Santra,Loganathan Mohan Pdf
This book highlights the evolution of, and novel challenges currently facing, nanomaterials science, nanoengineering, and nanotechnology, and their applications and development in the biological and biomedical fields. It details different nanoscale and nanostructured materials syntheses, processing, characterization, and applications, and considers improvements that can be made in nanostructured materials with their different biomedical applications. The book also briefly covers the state of the art of different nanomaterials design, synthesis, fabrication and their potential biomedical applications. It will be particularly useful for reading and research purposes, especially for science and engineering students, academics, and industrial researchers.
Nanomaterials in Biomedical Application and Biosensors (NAP-2019) by Alexander D. Pogrebnjak,Maksym Pogorielov,Roman Viter Pdf
This book covers novel and innovative technologies used in development, modeling, chemical/physical investigation and biomedical (in-vitro and in-vivo) trials of nanomaterials and nanocomposites. Novel methods for nanoparticle development and manufacturing are presented, as well as their safety and promising applications. In addition, the book highlights new frontiers in the use of metal / metal oxide nanoparticles, hierarchical nanostructures and organic coatings as sensors for detecting gases, inorganic and organic materials, including biosensors for bacteria and cancers. Organic nanoparticle composites for medical applications (tissue engineering, tissue replacement, regeneration, etc.), including hydroxyapatite NPs, are also covered, together with related in-vitro and preclinical investigations. In closing, the book shares recent findings on orthopedic and dental implant coatings using nanoparticles, their biological efficacy and safety.
Nanoparticles and their Biomedical Applications by Ashutosh Kumar Shukla Pdf
Nanotechnology is expected to bring revolutionary changes in a variety of fields. This volume describes nanoparticles and their biomedical applications, and covers metal nanoparticles, metal oxide nanoparticles, rare earth based nanoparticles and graphene oxide nanoparticles. It elaborates on a number of biomedical applications, including therapeutic applications. It addresses the topic of green synthesis, in view of increasing health and environmental concerns.
Silver Micro-Nanoparticles by Samir Kumar,Prabhat Kumar,Chandra Shakher Pathak Pdf
This book describes the different methodologies for producing and synthesizing silver nanoparticles (AgNPs) of various shapes and sizes. It also provides an in-depth understanding of the new methods for characterizing and modifying the properties of AgNPs as well as their properties and applications in various fields. This book is a useful resource for a wide range of readers, including scientists, engineers, doctoral and postdoctoral fellows, and scientific professionals working in specialized fields such as medicine, nanotechnology, spectroscopy, analytical chemistry diagnostics, and plasmonics.