Gold Nanoparticles In Biomedical Applications

Author : Lev Dykman,Nikolai Khlebtsov
Publisher : CRC Press
Page : 430 pages
File Size : 41,8 Mb
Release : 2017-12-12
Category : Medical
ISBN : 9781351360470

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Gold Nanoparticles in Biomedical Applications by Lev Dykman,Nikolai Khlebtsov Pdf

This book discusses fabrication of functionalized gold nanoparticles (GNPs) and multifunctional nanocomposites, their optical properties, and applications in biological studies. This is the very first book of its kind to comprehensively discuss published data on in vitro and in vivo biodistribution, toxicity, and uptake of GNP by mammalian cells providing a systematization of data over the GNP types and parameters, their surface functionalization, animal and cell models. As distinct from other related books, Gold Nanoparticles in Biomedical Applications discusses the immunological properties of GNPs and summarizes their applications as an antigen carrier and adjuvant in immunization for the preparation of antibodies in vivo. Although the potential of GNPs in nanobiotechnology has been recognized for the past decade, new insights into the unique properties of multifunctional nanostructures have recently emerged. With these developments in mind, this book unites ground breaking experimental data with a discussion of hybrid nanoparticle systems that combine different nanomaterials to create multifunctional structures. These novel hybrids constitute the material basis of theranostics, bringing together the advanced properties of functionalized GNPs and composites into a single multifunctional nanostructure with simultaneous diagnostic and therapeutic functions. Such nanohybrids can be physically and chemically tailored for a particular organ, disease, and patient thus making personalized medicine available.

Author : Lev Abramovich Dykman,Nikolai G. Khlebtsov
Publisher : Unknown
Page : 128 pages
File Size : 41,8 Mb
Release : 2018
Category : Biomedical engineering
ISBN : 1351360469

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Gold Nanoparticles in Biomedical Applications by Lev Abramovich Dykman,Nikolai G. Khlebtsov Pdf

Author : Egon Matijević
Publisher : Springer Science & Business Media
Page : 356 pages
File Size : 52,7 Mb
Release : 2011-09-18
Category : Science
ISBN : 9781461403791

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Fine Particles in Medicine and Pharmacy by Egon Matijević Pdf

Pharmaceutical manufacture is very exacting – for example, drugs must be uniform in size, shape, efficacy, bioavailability, and safety. The presence of different polymorphs in drug production is a serious problem, since different polymorphs differ in bioavailability, solubility, dissolution rate, chemical and physical stability, melting point, color, filterability, density, and flow properties. Fine Particles in Medicine and Pharmacy discusses particle size, shape, and composition and how they determine the choice of polymorph of a drug.

Author : Zheng-Rong Lu,Shinji Sakuma
Publisher : Humana
Page : 0 pages
File Size : 46,5 Mb
Release : 2015-11-09
Category : Medical
ISBN : 1493931202

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Nanomaterials in Pharmacology by Zheng-Rong Lu,Shinji Sakuma Pdf

This detailed volume aims to introduce nanomaterials as a new therapeutic regimen in treating human diseases. Divided into four sections, it explores inorganic nanomaterials, organic nanomaterials, pharmaceutical properties of nanomaterials, and applications of nanomaterials in medicine. Several examples of inorganic and organic nanomaterials are provided to demonstrate how to design and develop nanomaterials for pharmacological purposes. The key pharmaceutical properties, including biocompatibility, tissue interaction, pharmaceutics, and pharmacokinetics of nanomaterials are discussed with a focus on the safety and pharmaceutical considerations of nanomaterials in translational development. The pharmacological applications of nanomaterials are depicted in treating various human diseases, including cancer, cardiovascular diseases, immune disorders, infectious diseases, gastrointestinal disorders, bone diseases, respiratory disorders, and drug delivery. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of specifics and practical advice that ensures a smooth transition into the lab. Authoritative and enlightening, Nanomaterials in Pharmacology serves as an ideal guide to researchers investigating the potential benefits and risks of nanomaterials in pharmacology in order to avoid the pitfalls and to maximize the potential of this vital field of study.

Author : Abagail Jarnagin
Publisher : Nova Science Publishers
Page : 0 pages
File Size : 53,9 Mb
Release : 2013
Category : Gold
ISBN : 1622579275

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Gold Nanoparticles by Abagail Jarnagin Pdf

In this book, the authors present current research in the study of the synthesis, optical properties and applications for cancer treatment of gold nanoparticles. Topics discussed include the use of gold nanoparticles in cancer treatment and biomedical applications to target tumors and provide detection, drug carriers, gene silencing and radiotherapy; gold nanoparticle fabrication by laser ablation technique and their optical and morphological study; gold nanoparticles for metabolite imaging; formation of gold nanoparticles inside the corona of amphiphilic triblock copolymer micelles; and the intracellular delivery of gold nanoparticles and their application in nanomedicine.

Author : R. Navanietha Krishnaraj,Rajesh K. Sani
Publisher : John Wiley & Sons
Page : 416 pages
File Size : 48,7 Mb
Release : 2021-10-26
Category : Technology & Engineering
ISBN : 9781119617174

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Microbial Interactions at Nanobiotechnology Interfaces by R. Navanietha Krishnaraj,Rajesh K. Sani Pdf

MICROBIAL INTERACTIONS AT NANOBIOTECHNOLOGY INTERFACES This book covers a wide range of topics including synthesis of nanomaterials with specific size, shape, and properties, structure-function relationships, tailoring the surface of nanomaterials for improving the properties, interaction of nanomaterials with proteins/microorganism/eukaryotic cells, and applications in different sectors. This book also provides a strong foundation for researchers who are interested to venture into developing functionalized nanomaterials for any biological applications in their research. Practical concepts such as modelling nanomaterials, and simulating the molecular interactions with biomolecules, transcriptomic or genomic approaches, advanced imaging techniques to investigate the functionalization of nanomaterials/interaction of nanomaterials with biomolecules and microorganisms are some of the chapters that offer significant benefits to the researchers.

Author : Giuseppe Chirico,Mykola Borzenkov,Piersandro Pallavicini
Publisher : Springer
Page : 80 pages
File Size : 47,7 Mb
Release : 2015-08-03
Category : Technology & Engineering
ISBN : 9783319207681

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Gold Nanostars by Giuseppe Chirico,Mykola Borzenkov,Piersandro Pallavicini Pdf

This Brief focuses on the synthesis, functionalization techniques, optical properties and biomedical application of gold nanostars (GNS). Various facilities of gold nanostars synthesis as well as functionalization of GNS with PEG, organic dyes, bioactive compounds are discussed. The authors discuss physical origin of the Localized Surface Plasmon Resonances and the way the nano-environment affects them. The implication of the LSPR of gold nanostars surface enhanced Raman scattering is also discussed. The emphasis has been done on the application of GNS for current and emerge needs of medicine, biology and pharmacy. Moreover, properties of gold nanostars as contrast agents for in vivo imaging and interaction of GNS with cells are also discussed in this Brief.

Author : Eun Ji Chung,Lorraine Leon,Carlos Rinaldi
Publisher : Elsevier
Page : 440 pages
File Size : 42,5 Mb
Release : 2019-11-19
Category : Technology & Engineering
ISBN : 9780128166635

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Nanoparticles for Biomedical Applications by Eun Ji Chung,Lorraine Leon,Carlos Rinaldi Pdf

Nanoparticles for Biomedical Applications: Fundamental Concepts, Biological Interactions and Clinical Applications brings into one place information on the design and biomedical applications of different classes of nanoparticles. While aspects are dealt with in individual journal articles, there is not one source that covers this area comprehensively. This book fills this gap in the literature. Outlines an in-depth review of biomedical applications of a variety of nanoparticle classes Discusses the major techniques for designing nanoparticles for use in biomedicine Explores safety and regulatory aspects for the use of nanoparticles in biomedicine

Author : José Callejas-Fernández,Joan Estelrich,Manuel Quesada-Pérez,Jacqueline Forcada
Publisher : Royal Society of Chemistry
Page : 284 pages
File Size : 55,8 Mb
Release : 2014-07-17
Category : Medical
ISBN : 9781849738118

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Soft Nanoparticles for Biomedical Applications by José Callejas-Fernández,Joan Estelrich,Manuel Quesada-Pérez,Jacqueline Forcada Pdf

An overview of different soft nanoparticles including their synthesis, chararcterization and their current and potential uses in medicine and health.

Author : Jayanta Kumar Patra,Leonardo F. Fraceto,Gitishree Das,Estefânia Vangelie Ramos Campos
Publisher : Springer Nature
Page : 395 pages
File Size : 46,7 Mb
Release : 2020-04-06
Category : Science
ISBN : 9783030392468

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Green Nanoparticles by Jayanta Kumar Patra,Leonardo F. Fraceto,Gitishree Das,Estefânia Vangelie Ramos Campos Pdf

Nanotechnology is the application of science to control matter at the molecular level. It has become one of the most promising applied technologies in all areas of science. Nanoparticles have multi-functional properties and have created very interesting applications in various fields such as medicine, nutrition, bioenergy, agriculture and the environment. But the biogenic syntheses of monodispersed nanoparticles with specific sizes and shapes have been a challenge in biomaterial science. Nanoparticles are of great interest due to their extremely small size and large surface-to-volume ratio, which lead to both chemical and physical differences in their properties (e.g., mechanical properties, biological and sterical properties, catalytic activity, thermal and electrical conductivity, optical absorption and melting point) compared to bulk of the same chemical composition. Recently, however, synthesizing metal nanoparticles using green technology via microorganisms, plants, viruses, and so on, has been extensively studied and has become recognized as a green and efficient way for further exploiting biological systems as convenient nanofactories. Thus the biological synthesis of nanoparticles is increasingly regarded as a rapid, ecofriendly, and easily scaled-up technology. Today researchers are developing new techniques and materials using nanotechnology that may be suitable for plants to boost their native functions. Recently, biological nanoparticles were found to be more pharmacologically active than physico-chemically synthesized nanoparticles. Various applications of biosynthesized nanoparticles have been discovered, especially in the field of biomedical research, such as applications to specific delivery of drugs, use for tumor detection, angiogenesis, genetic disease and genetic disorder diagnosis, photoimaging, and photothermal therapy. Further, iron oxide nanoparticles have been applied to cancer therapy, hyperthermia, drug delivery, tissue repair, cell labeling, targeting and immunoassays, detoxification of biological fluids, magnetic resonance imaging, and magnetically responsive drug delivery therapy. Nanoparticle synthesis for plant byproducts for biomedical applications has vast potential. This book offers researchers in plant science and biomedicine the latest research and opportunity to develop new tools for the synthesis of environmentally friendly and cost-effective nanoparticles for applications in biomedicine as well as other various fields.

Author : P. E. Chow
Publisher : Unknown
Page : 0 pages
File Size : 49,9 Mb
Release : 2010
Category : Gold
ISBN : 1616680091

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Gold Nanoparticles by P. E. Chow Pdf

Due to their attractive electronic, optical, and thermal properties; gold nanoparticles (AuNPs) have emerged with great interest, as well as catalytic properties, in the fields of physics, chemistry, biology, medicine, material science and some interdisciplinary fields. This book examines a broad range of applications of gold nanoparticles such as: gold nanoparticles as an antigen carrier and as an adjuvant; laser synthesis of gold nanoparticles and the control over their properties; gold on carbon catalysts; gold nanoparticles as a delivery vehicle in biomedical applications; solution and solid-state methods to prepare Au nanoparticles; gold nanoparticles and their in-vitro property, the usefulness of gold nanoparticles in emerging infectious disease situations and a host of others.

Author : Alexandru Mihai Grumezescu
Publisher : William Andrew
Page : 530 pages
File Size : 49,9 Mb
Release : 2019-02-28
Category : Medical
ISBN : 9780128166307

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Biomedical Applications of Nanoparticles by Alexandru Mihai Grumezescu Pdf

Biomedical Applications of Nanoparticles describes the most interesting and investigated biomedical applications of nanoparticles, emphasizing their therapeutic impact. Progress made in the therapy of severe diseases, such as cancer and difficult infections is strictly correlated to the scientific progress and technological development in the field of materials science. Nanoparticles have numerous therapeutic applications, starting with the design of new drugs, delivery systems, therapeutic materials, and their contribution to the development of preventive strategies. The book highlights the impact of nanoparticles on the therapy of infections, antimicrobial effect and also anti-cancer strategies. Successful examples are given throughout the book, along with analysis in order to improve future outcomes of novel therapies. Highlights the term nanotherapeutics and presents several classifications of nanotherapeutics from different points-of-view Presents the recent progress related to nanotherapeutics in the oral cavity Provides the recent progress in the field of biomedical nanoparticles

Author : Jin-Chul Kim,Madhusudhan Alle,Azamal Husen
Publisher : Springer Nature
Page : 603 pages
File Size : 54,7 Mb
Release : 2022-01-19
Category : Medical
ISBN : 9783030842628

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Smart Nanomaterials in Biomedical Applications by Jin-Chul Kim,Madhusudhan Alle,Azamal Husen Pdf

With the start of 2020, the wrath of pandemic challenged the scientific community to develop more advanced drug delivery approaches for biomedical applications, endowing conventional drugs with additional therapeutic benefits and minimum side effects. Although significant advancements have been done in the field of drug delivery, there is a need to focus towards strategizing novel and improved drug delivery systems that should be convenient and cost-effective to the patients, and simultaneously they should also provide financial benefits to pharmaceutical companies. Controlled drug delivery technology offers ample opportunities and scope for improvising the therapeutic efficacy of drugs via optimizing the drug release rate and time. For this endeavour, smart nanomaterials have served as remarkable candidates for biomedical applications, owing to their ground-breaking properties and design. The development of such nanomaterials requires a broad knowledge related to their physio-chemical properties, molecular structure, mechanisms by which the nanomaterials interact with the cells, and methods by which drugs are released at the site of action. This knowledge must also be allied with the knowledge of signaling crosstalk mechanisms that are modulated by the nanomaterial-drugs composite. It can be anticipated that these emerging drug delivery technologies can facilitate the world to successfully encounter such pandemic outbursts in the future in a cost-effective and time-effective manner. The chapters in this book deal with the advanced technologies and approaches that can benefit advanced students, researchers, and industry experts in developing smart and intelligent nanomaterials for future biomedical applications, and development, manufacturing, and commercialization for controlled and targeted drug delivery.

Author : Rebeka Rudolf,Vojkan Lazić,Peter Majerič,Andrej Ivanič,Gregor Kravanja,Karlo T. Raić
Publisher : Springer Nature
Page : 112 pages
File Size : 49,7 Mb
Release : 2022-04-11
Category : Technology & Engineering
ISBN : 9783030987466

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Dental Gold Alloys and Gold Nanoparticles for Biomedical Applications by Rebeka Rudolf,Vojkan Lazić,Peter Majerič,Andrej Ivanič,Gregor Kravanja,Karlo T. Raić Pdf

This book focuses on recent advances in dental gold alloys and gold nanoparticles (GNPs) for biomedical applications. Dental gold alloys combine several highly desirable mechanical properties, such as high strength, ductility, and elasticity, with an extremely robust chemical stability in the mouth. Moreover, astonishing progress has been made in the use of GNPs as novel gold biomaterials that provide a multifunctional platform for cellular imaging, biosensing, and targeted drug delivery in tumour immunotherapy and photothermal therapy. Beginning with a comprehensive overview of the development and use of dental gold alloys, the book addresses the materials properties that are crucial for dental applications, focusing on aspects such as microstructure, chemical and mechanical stability, ageing, biocompatibility, and colour retention. The book then shifts focus to the use of GNPs in dental applications, delving into different techniques of GNP synthesis for specifically tailoring the size, shape, and stability of GNPs in biological media. In addition to these factors, it addresses how their exposure route, surface chemistry, as well as how the steric effects of their coating impact biodistribution and determine the level of GNP toxicity in the human body. Featuring topical literature reviews alongside up-to-date published experimental results, this book offers an attractive resource for practicing scientists and engineers working in the field of gold-based biomaterials.

Author : Sougata Jana,Subrata Jana
Publisher : Springer
Page : 451 pages
File Size : 52,8 Mb
Release : 2017-10-09
Category : Medical
ISBN : 9789811036477

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Particulate Technology for Delivery of Therapeutics by Sougata Jana,Subrata Jana Pdf

The book focuses on novel particulate technologies for the purpose of drug delivery to humans. Nowadays, macro and nano-scale particles are being investigated for targeted delivery of small and large biological macromolecules. The targeting of drugs can minimize the dosage regimen and reduces dose related potential toxicity of drug molecules, which in turn lead to increased potential compliance. Various types of organic, inorganic and polymer particles are currently being investigated. These are attracting the attention of the research workers in the field of drug delivery science and technology. This book covers polymersomes, inorganic- organic composites, gold nanoparticles biopolymer and synthetic polymer particles etc.All aspects of drug delivery in relation to each technology have been described including these advances, Easy to read and understand the content of each chapter Rich in up-to-date information regarding their application.