Biopharmaceutics And Pharmacokinetics Considerations

Author : Anonim
Publisher : Academic Press
Page : 754 pages
File Size : 52,8 Mb
Release : 2021-07-07
Category : Medical
ISBN : 9780128144268

Get Book

Biopharmaceutics and Pharmacokinetics Considerations by Anonim Pdf

Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Author : Rakesh Kumar Tekade
Publisher : Academic Press
Page : 816 pages
File Size : 52,9 Mb
Release : 2022-02-05
Category : Business & Economics
ISBN : 9780323913164

Get Book

Pharmacokinetics and Toxicokinetic Considerations - Vol II by Rakesh Kumar Tekade Pdf

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists. Allows readers to systematically integrate up-to-date research findings into their laboratory work Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment Provides clinical applications of concepts

Author : Milo Gibaldi
Publisher : Unknown
Page : 424 pages
File Size : 48,5 Mb
Release : 1991
Category : Medical
ISBN : UOM:39015018883739

Get Book

Biopharmaceutics and Clinical Pharmacokinetics by Milo Gibaldi Pdf

This updated introduction to the clinical applications of pharmacokinetics looks at gastrointestinal absorption, prolonged release medication, and drug disposition. The effects of disease, weight, age, sex and genetic factors on pharmacokinetic variability and drug response are detailed. Bioequivalence and regulatory considerations for generic drug.

Author : Rajesh Krishna,Lawrence Yu
Publisher : Springer Science & Business Media
Page : 416 pages
File Size : 51,8 Mb
Release : 2007-09-20
Category : Medical
ISBN : 9780387723792

Get Book

Biopharmaceutics Applications in Drug Development by Rajesh Krishna,Lawrence Yu Pdf

The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Author : John G. Wagner
Publisher : American Pharmaceutical Association
Page : 398 pages
File Size : 41,5 Mb
Release : 1971
Category : Medical
ISBN : UOM:39015010669912

Get Book

Biopharmaceutics and Relevant Pharmacokinetics by John G. Wagner Pdf

Author : Leon Shargel,Susanna Wu-Pong,Andrew B. C. Yu
Publisher : McGraw-Hill Medical Publishing
Page : 920 pages
File Size : 47,5 Mb
Release : 2005
Category : Medical
ISBN : UOM:39015059132483

Get Book

Applied Biopharmaceutics & Pharmacokinetics by Leon Shargel,Susanna Wu-Pong,Andrew B. C. Yu Pdf

Annotation The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Author : Leon Shargel,Andrew B. C. Yu
Publisher : McGraw-Hill/Appleton & Lange
Page : 625 pages
File Size : 54,9 Mb
Release : 1993
Category : Biopharmaceutics
ISBN : 0838502393

Get Book

Applied Biopharmaceutics and Pharmacokinetics by Leon Shargel,Andrew B. C. Yu Pdf

Author : Stephen H. Curry
Publisher : Wiley-Blackwell
Page : 330 pages
File Size : 54,7 Mb
Release : 1980
Category : Biopharmaceutics
ISBN : 0632006390

Get Book

Drug Disposition and Pharmacokinetics by Stephen H. Curry Pdf

Author : Leon Shargel,Andrew Yu,Susanna Wu-Pong
Publisher : McGraw Hill Professional
Page : 831 pages
File Size : 50,5 Mb
Release : 2012-04-11
Category : Medical
ISBN : 9780071603935

Get Book

Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition by Leon Shargel,Andrew Yu,Susanna Wu-Pong Pdf

A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.

Author : Hannah Batchelor
Publisher : John Wiley & Sons
Page : 324 pages
File Size : 54,5 Mb
Release : 2021-12-20
Category : Medical
ISBN : 9781119678281

Get Book

Biopharmaceutics by Hannah Batchelor Pdf

Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.

Author : Leon Shargel,Andrew B. C. Yu
Publisher : McGraw-Hill/Appleton & Lange
Page : 656 pages
File Size : 49,6 Mb
Release : 1993
Category : Medical
ISBN : UOM:39015029461012

Get Book

Applied Biopharmaceutics and Pharmacokinetics by Leon Shargel,Andrew B. C. Yu Pdf

The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Author : Leon Shargel,Susanna Wu-Pong,Andrew Yu
Publisher : McGraw Hill Professional
Page : 914 pages
File Size : 52,5 Mb
Release : 2004-09-09
Category : Medical
ISBN : 9780071501873

Get Book

Applied Biopharmaceutics & Pharmacokinetics, Fifth Edition by Leon Shargel,Susanna Wu-Pong,Andrew Yu Pdf

The most comprehensive text on the practical applications of biopharmaceuticals and pharmacokinetics! 4 STAR DOODY'S REVIEW! "The updated edition provides the reader with a solid foundation in the basic principles of pharmacokinetics and biopharmaceutics. Students will be able to apply the information to their clinical practice and researchers will find this to be a valuable reference. This modestly priced book should be the gold standard for student use."--Doody's Review Service The primary emphasis of this book is on the application and understanding of concepts. Basic theoretical discussions of the principles of biopharmaceutics and pharmacokinetics are provided, along with illustrative examples and practice problems and solutions to help the student gain skill in practical problem solving.

Author : Milo Gibaldi
Publisher : Unknown
Page : 196 pages
File Size : 43,7 Mb
Release : 1977
Category : Medical
ISBN : UOM:39015003205625

Get Book

Biopharmaceutics and Clinical Pharmacokinetics by Milo Gibaldi Pdf

Author : Alan Talevi
Publisher : Springer Nature
Page : 1209 pages
File Size : 51,6 Mb
Release : 2022-06-14
Category : Medical
ISBN : 9783030848606

Get Book

The ADME Encyclopedia by Alan Talevi Pdf

The ADME Encyclopedia covers pharmacokinetic phenomena (Absorption, Distribution, Metabolism and Excretion processes) and their relationship with the design of pharmaceutical carriers and the success of drug therapies. It covers both basic and advanced knowledge, serving as introductory material for students of biomedical careers and also as reference, updated material for graduates and professionals working in any field related to pharmaceutical sciences (medicine, pharmaceutical technology, materials science, medicinal chemistry). Structured as alphabetically ordered entries with cross-references, the Encyclopedia not only provides basic knowledge on ADME processes, but also detailed entries on some advanced subjects such as drug transporters, last generation pharmaceutical carriers, pharmacogenomics, personalized medicine, bioequivalence studies, biowaivers, biopharmaceuticals, gene delivery, pharmacometrics, pharmacokinetic drug interactions or in silico and in vitro assessment of ADME properties

Author : Chi-Jen Lee,Lucia H. Lee,Christopher L. Wu,Benjamin R. Lee,Mei-Ling Chen
Publisher : CRC Press
Page : 520 pages
File Size : 54,6 Mb
Release : 2005-09-19
Category : Medical
ISBN : 9781420039146

Get Book

Clinical Trials of Drugs and Biopharmaceuticals by Chi-Jen Lee,Lucia H. Lee,Christopher L. Wu,Benjamin R. Lee,Mei-Ling Chen Pdf

The pharmaceutical industry is on the verge of an exciting and challenging century. Advances in pharmaceutical sciences have dramatically changed the processes of discovery and development of new therapeutic drugs and, in turn, resulted in an extraordinary increase in the potential prophylactic and therapeutic interventions. In this atmosphere, an