Biophysics Of Infection

Author : Mark C. Leake
Publisher : Springer
Page : 362 pages
File Size : 46,6 Mb
Release : 2016-05-18
Category : Science
ISBN : 9783319321899

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Biophysics of Infection by Mark C. Leake Pdf

This book describes modern biophysical techniques that enable us to understand and examine dynamic processes of infection at the molecular level. Cutting-edge research articles, laboratory protocols, case studies and up-to-date reviews cover topics such as single-molecule observation of DNA replication repair pathways in E. coli; evolution of drug resistance in bacteria; restriction enzymes as barriers to horizontal gene transfer in Staphylococcus aureus; infectious and bacterial pathogen biofilms; killing infectious pathogens through DNA damage; bacterial surfaces in host-pathogen interactions; bacterial gene regulation by riboswitches; transcription regulation in enterobacterial pathogens; the bacterial flagellar motor; initial surface colonization by bacteria; Salmonella Typhi host restrictions; as well as monitoring proton motive force in bacteria; microbial pathogens using digital holography; mathematical modelling of microbial pathogen motility; neutron reflectivity in studying bacterial membranes; force spectroscopy in studying infection and 4D multi-photon imaging to investigate immune responses. The focus is on the development and application of complex techniques and protocols at the interface of life sciences and physics, which increase the physiological relevance of biophysical investigations.

Author : Guillaume Duménil,Sven van Teeffelen
Publisher : Springer Nature
Page : 141 pages
File Size : 44,8 Mb
Release : 2020-09-07
Category : Medical
ISBN : 9783030468866

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Physical Microbiology by Guillaume Duménil,Sven van Teeffelen Pdf

This book emerges from the idea that specific physics-inspired approaches are necessary to understand different stage of bacterial physiology and the infections they cause. Many aspects of bacterial life depend on processes typically described by physical laws: The rheology of biofilms is determined by complex cohesive forces. Physical laws of diffusion are essential to all processes of bacterial metabolism. The formation of the numerous bacterial biomacromolecules require complex self-organization processes and their function are powered by potent molecular motors. Host-pathogen interactions during infection frequently occur in environments determined by fluid mechanics. In this book, different chapters represent research at the interface between microbiology and physics. Topics range from intracellular organization to cell-cell interactions. A good part of the book is devoted to mechanical forces, which are involved in the function of elaborate bacterial nanomachines, chromosome segregation, and cell division. The effect of bacterial toxins provides an example of the alteration of cellular membrane properties by bacteria. Symmetrically, histones from mammalian cells alter bacterial membranes as a defense mechanism during infection. The editors of this book, Guillaume Duménil and Sven van Teeffelen, have selected researchers at the forefront of research in physical microbiology to provide the most recent view in this fast-moving field. The contents of this book are designed to be accessible for scientists with training in biology and for scientists with training in physics. The objective is to provide a fresh perspective on microbiology and infection by highlighting recent multidisciplinary research and favor rapid advances at this fruitful interface.

Author : John Colter
Publisher : Elsevier
Page : 747 pages
File Size : 47,7 Mb
Release : 2012-12-02
Category : Science
ISBN : 9780323142731

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The Molecular Biology of Viruses by John Colter Pdf

The Molecular Biology of Viruses is a collection of manuscripts presented at the Third Annual International Symposium of the Molecular Biology of Viruses, held in the University of Alberta, Canada on June 27-30, 1966, sponsored by the Faculty of Medicine of the University of Alberta. This book is organized into eight parts encompassing 36 chapters that emphasize the biosynthetic steps involved in polymer duplication. The first two parts explore the specialized processes of the cycle of virulent and temperate bacteriophage multiplication. These parts also deal with the production, regulation of development, and selectivity of these bacteriophages. The subsequent two parts look into the heterozygosity, mutation, structure, function, and mode of infection of single-stranded DNA and RNA bacteriophages. The discussions then shift to the biological and physicochemical aspects, biosynthesis, translation, genetics, and replication of mammalian DNA and RNA viruses. The concluding parts describe the homology, interaction, functions, mechanism of transformation, metabolism, and carcinogenic activity of oncogenic viruses. This book is of great benefit to biochemists, biophysicists, geneticists, microbiologists, and virologists.

Author : P. J Klasse
Publisher : Academic Press
Page : 458 pages
File Size : 51,7 Mb
Release : 2015-01-08
Category : Science
ISBN : 0128024615

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The Molecular Basis of Viral Infection by P. J Klasse Pdf

Virology is in a sense both one of the most important precursors and one of the most significant beneficiaries of structural and cellular molecular biology. Numerous breakthroughs in our understanding of the molecular interactions of viruses with host cells are ready for translation into medically important applications such as the prevention and treatment of viral infections. This book collects a wide variety of examples of frontline research into molecular aspects of viral infections from virological, immunological, cell- and molecular-biological, structural, and theoretical perspectives. Contributors are world leaders in their fields of study and represent prestigious academic and research institutions Review articles vary vastly in scope: some focus on a narrowly defined scientific problem of one particular virus with careful introduction for the non-specialist; others are essays in general and comparative virology with forays into specific viral species or molecules The different perspectives complement each other and collectively the contributions provide an impression of the fast-moving frontlines of virology while showing how the problems have evolved Structural data are presented through high-quality illustrations

Author : Dirk Linke,Adrian Goldman
Publisher : Springer Science & Business Media
Page : 376 pages
File Size : 49,9 Mb
Release : 2011-05-10
Category : Medical
ISBN : 9789400709409

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Bacterial Adhesion by Dirk Linke,Adrian Goldman Pdf

Over the last few years, bacterial adhesion has become a more and more important and active scientific area, but the field lacks communication and scientific exchange between medical and microbiology researchers who work with the relevant biological systems, and biochemists, structural biologists and physicists, who know and understand the physical methods best suited to investigate the phenomenon at the molecular level. The field consequently would benefit from a cross-disciplinary conference enabling such communication. This book tries to bridge the gap between the disciplines.

Author : M.R. Escobar,J.P. Utz
Publisher : Springer
Page : 357 pages
File Size : 53,6 Mb
Release : 2013-10-20
Category : Medical
ISBN : 1489937501

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Infection by M.R. Escobar,J.P. Utz Pdf

This comprehensive treatise on the reticuloendothelial system is a project jointly shared by individual members of the Reticuloendothelial (RE) Society and bio medical scientists in general who are interested in the intricate system of cells and molecular moieties derived from those cells that constitute the RES. It may now be more fashionable in some quarters to consider these cells as part of what is called the mononuc1ear phagocytic system or the lymphoreticular system. Nevertheless, because of historical developments and current interest in the subject by investigators from many diverse areas, it seems advantageous to present in one comprehensive treatise current information and knowledge con cerning basic aspects of the RES, such as morphology, biochemistry, phylogeny and ontogeny, physiology, and pharmacology, as well as c1inical areas inc1uding immunopathology, cancer, infectious diseases, allergy, and hypersensitivity. It is anticipated that, by presenting information concerning these apparently het erogeneous topics under the unifying umbrella of the RES, attention will be focused on the similarities as well as interactions among the cell types constitut ing the RES from the viewpoint of various disciplines. The treatise editors and their editorial board, consisting predominantly of the editors of individual vol umes, are extremely grateful for the enthusiastic cooperation and enormous task undertaken by members of the biomedical community in general and especially by members of the American as well as European and Japanese Reticuloen dothelial Societies.

Author : Mohammad Ashrafuzzaman
Publisher : CRC Press
Page : 603 pages
File Size : 40,7 Mb
Release : 2023-12-15
Category : Science
ISBN : 9781003821649

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Introduction to Modern Biophysics by Mohammad Ashrafuzzaman Pdf

This textbook provides an introduction to the fundamental and applied aspects of biophysics for advanced undergraduate and graduate students of physics, chemistry, and biology. The application of physics principles and techniques in exploring biological systems has long been a tradition in scientific research. Biological systems hold naturally inbuilt physical principles and processes which are popularly explored. Systematic discoveries help us understand the structures and functions of individual biomolecules, biomolecular systems, cells, organelles, tissues, and even the physiological systems of animals and plants. Utilizing a physics- based scientific understanding of biological systems to explore disease is at the forefront of applied scientific research. This textbook covers key breakthroughs in biophysics whilst looking ahead to future horizons and directions of research. It contains models based on both classical and quantum mechanical treatments of biological systems. It explores diseases related to physical alterations in biomolecular structures and organizations alongside drug discovery strategies. It also discusses the cutting- edge applications of nanotechnologies in manipulating nanoprocesses in biological systems. Key Features: • Presents an accessible introduction to how physics principles and techniques can be used to understand biological and biochemical systems. • Addresses natural processes, mutations, and their purposeful manipulation. • Lays the groundwork for vitally important natural scientific, technological, and medical advances. Mohammad Ashrafuzzaman, a biophysicist and condensed matter scientist, is passionate about investigating biological and biochemical processes utilizing physics principles and techniques. He is a professor of biophysics at King Saud University’s Biochemistry Department in the College of Science, Riyadh, Saudi Arabia; the co- founder of MDT Canada Inc., and the founder of Child Life Development Institute, Edmonton, Canada. He has authored Biophysics and Nanotechnology of Ion Channels, Nanoscale Biophysics of the Cell, and Membrane Biophysics. He has also published about 50 peer- reviewed articles and several patents, edited two books, and has been serving on the editorial boards of Elsevier and Bentham Science journals. Dr. Ashrafuzzaman has held research and academic ranks at Bangladesh University of Engineering & Technology, University of Neuchatel (Switzerland), Helsinki University of Technology (Finland), Weill Medical College of Cornell University (USA), and University of Alberta (Canada). During 2013– 2018 he also served as a Visiting Professor at the Departments of Oncology, and Medical Microbiology and Immunology, of the University of Alberta. Dr. Ashrafuzzaman earned his highest academic degree, Doctor of Science (D.Sc.) in condensed matter physics from the University of Neuchatel, Switzerland in 2004.

Author : Bruce Alberts
Publisher : Unknown
Page : 0 pages
File Size : 54,7 Mb
Release : 2002
Category : Cytology
ISBN : 0815332181

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Molecular Biology of The Cell by Bruce Alberts Pdf

Author : Anonim
Publisher : ScholarlyEditions
Page : 422 pages
File Size : 53,8 Mb
Release : 2012-12-26
Category : Medical
ISBN : 9781464993763

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Hemic and Immune Systems—Advances in Research and Application: 2012 Edition by Anonim Pdf

Hemic and Immune Systems—Advances in Research and Application: 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Hemic and Immune Systems. The editors have built Hemic and Immune Systems—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Hemic and Immune Systems in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Hemic and Immune Systems—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Yan Shi,Erdinc Sezgin,Wei Chen
Publisher : Frontiers Media SA
Page : 116 pages
File Size : 44,9 Mb
Release : 2021-11-15
Category : Medical
ISBN : 9782889716340

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The Role of Biomembranes and Biophysics in Immune Cell Signaling by Yan Shi,Erdinc Sezgin,Wei Chen Pdf

Author : Malgorzata Lekka,Daniel Navajas,Manfred Radmacher,Alessandro Podestà
Publisher : Walter de Gruyter GmbH & Co KG
Page : 372 pages
File Size : 45,7 Mb
Release : 2023-02-20
Category : Science
ISBN : 9783110989380

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Biomedical Applications by Malgorzata Lekka,Daniel Navajas,Manfred Radmacher,Alessandro Podestà Pdf

The mechanical properties of cells can be used to distinguish pathological from normal cells and tissues in many diseases. This book will outline the physics behind cell and tissue mechanics, describe the methods which can be used to determine their mechanical properties, and present various diseases in which a mechanical fingerprint could be established. The book is designed to not require a background in either Physics or Life Sciences.

Author : Anonim
Publisher : ScholarlyEditions
Page : 1160 pages
File Size : 50,7 Mb
Release : 2013-05-01
Category : Science
ISBN : 9781490106106

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Issues in Biophysics and Geophysics Research and Application: 2013 Edition by Anonim Pdf

Issues in Biophysics and Geophysics Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Geophysics. The editors have built Issues in Biophysics and Geophysics Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Geophysics in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Biophysics and Geophysics Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Author : Anonim
Publisher : Unknown
Page : 280 pages
File Size : 46,8 Mb
Release : 1976
Category : Biochemistry
ISBN : UOM:49015002042100

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Progress in Biophysics and Biophysical Chemistry by Anonim Pdf

Author : J. A. V. Butler,H. E. Huxley,R. E. Zirkle
Publisher : Elsevier
Page : 352 pages
File Size : 52,6 Mb
Release : 2016-07-04
Category : Science
ISBN : 9781483149882

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Progress in Biophysics and Biophysical Chemistry by J. A. V. Butler,H. E. Huxley,R. E. Zirkle Pdf

Progress in Biophysics and Biophysical Chemistry, Volume 12, provides an overview of the state of knowledge in biophysics and biological chemistry. The book begins with a study on cell division synchronization. This is followed by separate chapters on the biology and function of the nucleolus; the nature of ribosomes and their involvement in protein synthesis; taste receptor stimulation; and the various methods developed for quantitative estimation of the amount of dye deposited in a stained preparation as well as some of the associated theoretical and practical implications. Subsequent chapters deal with the preparation, fractionation, physical properties, analysis, and functions of histones; and the use of tritium labelled DNA precursors in autoradiography.

Author : Ferric C. Fang
Publisher : Springer Science & Business Media
Page : 524 pages
File Size : 44,9 Mb
Release : 2007-05-08
Category : Medical
ISBN : 9780306468162

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Nitric Oxide and Infection by Ferric C. Fang Pdf

Familiarity with nitric oxide is essential to a modern understanding of pathophysiologic mechanisms of infectious disease. Recent research has established nitric oxide and related reactive nitrogen intermediates to be important molecular mediators of diverse physiologic processes such as control of vascular tone, regulation of the immune system, and microbial and tumor cell growth. This book contains chapters by the leading researchers in the field and examines the biology and biochemistry of nitric oxide and its role in a variety of specific infections ranging from sepsis, tuberculosis and malaria to viral myocarditis, influenza, and AIDS.