Bioprocessing For Biomolecules Production

Author : Gustavo Molina,Vijai Kumar Gupta,Brahma N. Singh,Nicholas Gathergood
Publisher : John Wiley & Sons
Page : 532 pages
File Size : 54,6 Mb
Release : 2020-01-21
Category : Technology & Engineering
ISBN : 9781119434320

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Bioprocessing for Biomolecules Production by Gustavo Molina,Vijai Kumar Gupta,Brahma N. Singh,Nicholas Gathergood Pdf

Presents the many recent innovations and advancements in the field of biotechnological processes This book tackles the challenges and potential of biotechnological processes for the production of new industrial ingredients, bioactive compounds, biopolymers, energy sources, and compounds with commercial/industrial and economic interest by performing an interface between the developments achieved in the recent worldwide research and its many challenges to the upscale process until the adoption of commercial as well as industrial scale. Bioprocessing for Biomolecules Production examines the current status of the use and limitation of biotechnology in different industrial sectors, prospects for development combined with advances in technology and investment, and intellectual and technical production around worldwide research. It also covers new regulatory bodies, laws and regulations, and more. Chapters look at biological and biotechnological processes in the food, pharmaceutical, and biofuel industries; research and production of microbial PUFAs; organic acids and their potential for industry; second and third generation biofuels; the fermentative production of beta-glucan; and extremophiles for hydrolytic enzymes productions. The book also looks at bioethanol production from fruit and vegetable wastes; bioprocessing of cassava stem to bioethanol using soaking in aqueous ammonia pretreatment; bioprospecting of microbes for bio-hydrogen production; and more. Provides up to date information about the advancements made on the production of important biotechnological ingredients Complete visualization of the general developments of world research around diverse products and ingredients of technological, economic, commercial and social importance Investigates the use and recovery of agro-industrial wastes in biotechnological processes Includes the latest updates from regulatory bodies for commercialization feasibility Offering new products and techniques for the industrial development and diversification of commercial products, Bioprocessing for Biomolecules Production is an important book for graduate students, professionals, and researchers involved in food technology, biotechnology; microbiology, bioengineering, biochemistry, and enzymology.

Author : Shang-Tian Yang
Publisher : Elsevier
Page : 684 pages
File Size : 52,8 Mb
Release : 2011-08-11
Category : Technology & Engineering
ISBN : 0080466710

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Bioprocessing for Value-Added Products from Renewable Resources by Shang-Tian Yang Pdf

Bioprocessing for Value-Added Products from Renewable Resources provides a timely review of new and unconventional techniques for manufacturing high-value products based on simple biological material. The book discusses the principles underpinning modern industrial biotechnology and describes a unique collection of novel bioprocesses for a sustainable future. This book begins in a very structured way. It first looks at the modern technologies that form the basis for creating a bio-based industry before describing the various organisms that are suitable for bioprocessing - from bacteria to algae - as well as their unique characteristics. This is followed by a discussion of novel, experimental bioprocesses, such as the production of medicinal chemicals, the production of chiral compounds and the design of biofuel cells. The book concludes with examples where biological, renewable resources become an important feedstock for large-scale industrial production. This book is suitable for researchers, practitioners, students, and consultants in the bioprocess and biotechnology fields, and for others who are interested in biotechnology, engineering, industrial microbiology and chemical engineering. ·Reviews the principles underpinning modern industrial biotechnology ·Provides a unique collection of novel bioprocesses for a sustainable future ·Gives examples of economical use of renewable resources as feedstocks ·Suitable for both non-experts and experts in the bioproduct industry

Author : Vijai Kumar Gupta,Satyajit D. Sarker,Minaxi Sharma,Maria Elida Pirovani,Zeba Usmani,Chelliah Jayabaskaran
Publisher : John Wiley & Sons
Page : 500 pages
File Size : 43,6 Mb
Release : 2022-04-11
Category : Technology & Engineering
ISBN : 9781119769576

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Biomolecules from Natural Sources by Vijai Kumar Gupta,Satyajit D. Sarker,Minaxi Sharma,Maria Elida Pirovani,Zeba Usmani,Chelliah Jayabaskaran Pdf

Biomolecules from Natural Sources An up-to-date exploration of new and novel biomolecules In Biomolecules from Natural Sources: Advances and Applications, a team of accomplished researchers delivers up-to-date information on various bioresources, bioprocessing, production, mechanisms of action for selective bioactivity, biochemistry, targeted therapeutic roles and the advancements made on their bioactive potentials of new and novel biomolecules. The book presents recent trends in new and novel biomolecules and their identification, characterization, and potential applications. The selected contributions canvas a variety of breakthroughs in the understanding and applications of naturally derived biomolecules. Biomolecules from Natural Sources: Advances and Applications is an exhaustive collection of research and information, as well as an insightful and interdisciplinary treatment of a rapidly developing field. Readers will also find: A thorough introduction to phenolics from natural sources and plant-based natural artemisinin and its biomedical applications Comprehensive explorations of protein structure, function, and specificity and the pharmacological potential of pigments Practical discussions of biomolecules obtained through food biotechnology and the biological activities of natural glycosides In-depth examinations of biomolecules from basil and their pharmacological significance Perfect for biotechnologists, food technologists, and plant biologists, Biomolecules from Natural Sources: Advances and Applications will also earn a place in the libraries of bioprocessing engineers, as well as undergraduate and postgraduate students of biochemistry.

Author : Claire Komives,Weichang Zhou
Publisher : John Wiley & Sons
Page : 288 pages
File Size : 46,8 Mb
Release : 2018-12-27
Category : Science
ISBN : 9781118361986

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Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts by Claire Komives,Weichang Zhou Pdf

Written for industrial and academic researchers and development scientists in the life sciences industry, Bioprocessing Technology for Production of Biopharmaceuticals and Bioproducts is a guide to the tools, approaches, and useful developments in bioprocessing. This important guide: • Summarizes state-of-the-art bioprocessing methods and reviews applications in life science industries • Includes illustrative case studies that review six milestone bio-products • Discuses a wide selection of host strain types and disruptive bioprocess technologies

Author : Ganapathy Subramanian
Publisher : Wiley-VCH
Page : 220 pages
File Size : 51,7 Mb
Release : 1998-07
Category : Biotechnology
ISBN : 3527288775

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Bioseparation and Bioprocessing by Ganapathy Subramanian Pdf

Author : Shiburaj Sugathan,N. S. Pradeep,Sabu Abdulhameed
Publisher : Springer
Page : 438 pages
File Size : 45,8 Mb
Release : 2017-05-26
Category : Science
ISBN : 9789811042843

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Bioresources and Bioprocess in Biotechnology by Shiburaj Sugathan,N. S. Pradeep,Sabu Abdulhameed Pdf

This book is a compilation of detailed articles on various products and services that can be derived from bioresources through bioprocess. It offers in-depth discussions and case studies on commercially and therapeutically important enzymes, antimicrobials, anti-cancer molecules and anti-inflammatory substances. It also includes a separate section on emerging trends in bioactive substances research. This unique book is a valuable source of information for biotechnologists and bioprocess experts as well as academics and researchers who are actively involved in product and process development.

Author : Owen P. Ward
Publisher : Springer Science & Business Media
Page : 208 pages
File Size : 44,8 Mb
Release : 2012-12-06
Category : Science
ISBN : 9781461539148

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Bioprocessing by Owen P. Ward Pdf

Methods for processing of biological materials into useful products represent essential core manufacturing activities of the food, chemical and pharmaceutical industries. On the one hand the techniques involved include well established process engineering methodologies such as mixing, heat transfer, size modification and a variety of separatIon and fermentation procedures. In addition, new bioprocessing practices arising from the exciting recent advances in biotech nology, including innovative fermentation cell culture and enzyme based operations, are rapidly extending the frontiers of bioprocessing. These develop ments are resulting in the introduction to the market place of an awesome range of novel biological products having unique applications. Indeed, the United States Office of Technology Assessment· has concluded that 'competitive advantage in areas related to biotechnology may depend as much on developments in bioprocess engineering as on innovations in genetics, immunology and other areas of basic science'. Advances in analytical instrumentation, computerization and process automation are playing an important role in process control and optimization and in the maintenance of product quality and consistency characteristics. Bioprocessing represents the industrial practice of biotechnology and is multidisciplinary in nature, integrating the biological, chemical and engineering sciences. This book discusses the individual unit operations involved and describes a wide variety of important industrial bioprocesses. I am very grateful to Sanjay Thakur who assisted me in the collection of material for this book.

Author : Kenneth E. Avis,Vincent L. Wu
Publisher : CRC Press
Page : 400 pages
File Size : 44,9 Mb
Release : 2020-08-14
Category : Medical
ISBN : 9781000161649

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Biotechnology and Biopharmaceutical Manufacturing, Processing, and Preservation by Kenneth E. Avis,Vincent L. Wu Pdf

In this unique book, experts describe practices applicable to the large-scale processing of biotechnological products. Beginning with processing and bulk storage preservation techniques, the book provides strategies for improving efficiency of process campaigns of multiple products and manufacturing facilities for such processing techniques. Large-scale chromatography for the purification of biomolecules in manufacturing and lyophilization of protein pharmaceuticals are discussed. Includes a case study on blow-fill-seal processing technology and a chapter on economic and cost factors for bioprocess engineering.

Author : Sarfaraz K. Niazi,Justin L. Brown
Publisher : CRC Press
Page : 746 pages
File Size : 46,9 Mb
Release : 2017-07-27
Category : Medical
ISBN : 9781466585744

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Fundamentals of Modern Bioprocessing by Sarfaraz K. Niazi,Justin L. Brown Pdf

Biological drug and vaccine manufacturing has quickly become one of the highest-value fields of bioprocess engineering, and many bioprocess engineers are now finding job opportunities that have traditionally gone to chemical engineers. Fundamentals of Modern Bioprocessing addresses this growing demand. Written by experts well-established in the field, this book connects the principles and applications of bioprocessing engineering to healthcare product manufacturing and expands on areas of opportunity for qualified bioprocess engineers and students. The book is divided into two sections: the first half centers on the engineering fundamentals of bioprocessing; while the second half serves as a handbook offering advice and practical applications. Focused on the fundamental principles at the core of this discipline, this work outlines every facet of design, component selection, and regulatory concerns. It discusses the purpose of bioprocessing (to produce products suitable for human use), describes the manufacturing technologies related to bioprocessing, and explores the rapid expansion of bioprocess engineering applications relevant to health care product manufacturing. It also considers the future of bioprocessing—the use of disposable components (which is the fastest growing area in the field of bioprocessing) to replace traditional stainless steel. In addition, this text: Discusses the many types of genetically modified organisms Outlines laboratory techniques Includes the most recent developments Serves as a reference and contains an extensive bibliography Emphasizes biological manufacturing using recombinant processing, which begins with creating a genetically modified organism using recombinant techniques Fundamentals of Modern Bioprocessing outlines both the principles and applications of bioprocessing engineering related to healthcare product manufacturing. It lays out the basic concepts, definitions, methods and applications of bioprocessing. A single volume comprehensive reference developed to meet the needs of students with a bioprocessing background; it can also be used as a source for professionals in the field.

Author : National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Bioprocess Engineering
Publisher : National Academies Press
Page : 133 pages
File Size : 46,6 Mb
Release : 1992-02-01
Category : Science
ISBN : 9780309047852

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Putting Biotechnology to Work by National Research Council,Division on Earth and Life Studies,Commission on Life Sciences,Committee on Bioprocess Engineering Pdf

The ability of the United States to sustain a dominant global position in biotechnology lies in maintaining its primacy in basic life-science research and developing a strong resource base for bioprocess engineering and bioproduct manufacturing. This book examines the status of bioprocessing and biotechnology in the United States; current bioprocess technology, products, and opportunities; and challenges of the future and what must be done to meet those challenges. It gives recommendations for action to provide suitable incentives to establish a national program in bioprocess-engineering research, development, education, and technology transfer.

Author : Jochen Schmid,Julia Fariña,Bernd Rehm,Volker Sieber
Publisher : Frontiers Media SA
Page : 163 pages
File Size : 43,8 Mb
Release : 2016-06-24
Category : Electronic book
ISBN : 9782889198436

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Microbial Exopolysaccharides: From Genes to Applications by Jochen Schmid,Julia Fariña,Bernd Rehm,Volker Sieber Pdf

Microbial polysaccharides represent an attractive alternative to those from plants or macro algae. They can be produced from renewable sources including lignocellulosic waste streams. Their production does not depend on geographical constraints and/or seasonal limitations. Additionally the manipulation of biosynthetic pathways to enhance productivity or to influence the chemical polysaccharide composition is comparatively easy in bacteria. Microbial exopolysaccharides represents a valuable resource of biogenic and biodegradable polymers, suitable to replace petro based polymers in various technical applications. Furthermore, biocompatible exopolysaccharides are very attractive in medical applications, such as drug delivery systems, use as vaccines or nanoparticles. This research topic will depict the status quo, as well as the future needs in the field of EPS and biofilm research. Starting from the unexplored diversity of microbial polysaccharide producers to production processes and possibilities for modifications, to enhance the already high number of functionalities based on the chemical structures. An overview of the recent and future applications will be given, and the necessity in unravelling the biosynthesis of microbial exopolysaccharide producers is depicted, highlighting the future trend of tailor made polymers. Constraints in structure analysis of these highly complex biogenic polymers are described and different approaches to solve the restrictions in imaging and NMR analysis will be given. Therefore; this research topic comprises the whole process from genes to applications.

Author : Sudhir P. Singh,Santosh Kumar Upadhyay
Publisher : John Wiley & Sons
Page : 516 pages
File Size : 49,9 Mb
Release : 2023-06-07
Category : Science
ISBN : 9781119874089

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Microbial Bioreactors for Industrial Molecules by Sudhir P. Singh,Santosh Kumar Upadhyay Pdf

Microbial Bioreactors for Industrial Molecules Harness the planet’s most numerous resources with this comprehensive guide Microorganisms constitute the invisible majority of all living creatures on Earth. They are found virtually everywhere on the planet, including in environments too extreme for any larger organisms to exist. They form a hugely significant resource whose potential value for human society cannot be overlooked. The creation of microorganism- based bioreactors for the industrial production of valuable biomolecules has the potential to revolutionize a range of industries and fields. Microbial Bioreactors for Industrial Molecules provides a comprehensive introduction to these bioresources. It covers all potential approaches to the use of microbial technology and the production of high-value biomolecules for the pharmaceutical, cosmetic, and agricultural industries, among others. The book’s rigorous detail and global, holistic approach to harnessing the power of the planetary microbiome make it an invaluable introduction to this growing area of research and production. Readers will also find: Detailed coverage of basic, applied, biosynthetic, and translational approaches to the use of microbial technology Discussion of industrially produced microbe-borne enzymes including invertase, lipase, keratinase, protease, and more Approaches for using microbial bioreactors to generate biofuels Microbial Bioreactors for Industrial Molecules is essential for scientists and researchers in microbiology and biotechnology, as well as for professionals in the biotech industries and graduate students studying the applications of the life sciences.

Author : Pauline M. Doran
Publisher : Elsevier
Page : 455 pages
File Size : 40,6 Mb
Release : 1995-04-03
Category : Science
ISBN : 9780080528120

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Bioprocess Engineering Principles by Pauline M. Doran Pdf

The emergence and refinement of techniques in molecular biology has changed our perceptions of medicine, agriculture and environmental management. Scientific breakthroughs in gene expression, protein engineering and cell fusion are being translated by a strengthening biotechnology industry into revolutionary new products and services. Many a student has been enticed by the promise of biotechnology and the excitement of being near the cutting edge of scientific advancement. However, graduates trained in molecular biology and cell manipulation soon realise that these techniques are only part of the picture. Reaping the full benefits of biotechnology requires manufacturing capability involving the large-scale processing of biological material. Increasingly, biotechnologists are being employed by companies to work in co-operation with chemical engineers to achieve pragmatic commercial goals. For many years aspects of biochemistry and molecular genetics have been included in chemical engineering curricula, yet there has been little attempt until recently to teach aspects of engineering applicable to process design to biotechnologists. This textbook is the first to present the principles of bioprocess engineering in a way that is accessible to biological scientists. Other texts on bioprocess engineering currently available assume that the reader already has engineering training. On the other hand, chemical engineering textbooks do not consider examples from bioprocessing, and are written almost exclusively with the petroleum and chemical industries in mind. This publication explains process analysis from an engineering point of view, but refers exclusively to the treatment of biological systems. Over 170 problems and worked examples encompass a wide range of applications, including recombinant cells, plant and animal cell cultures, immobilised catalysts as well as traditional fermentation systems. * * First book to present the principles of bioprocess engineering in a way that is accessible to biological scientists * Explains process analysis from an engineering point of view, but uses worked examples relating to biological systems * Comprehensive, single-authored * 170 problems and worked examples encompass a wide range of applications, involving recombinant plant and animal cell cultures, immobilized catalysts, and traditional fermentation systems * 13 chapters, organized according to engineering sub-disciplines, are groupled in four sections - Introduction, Material and Energy Balances, Physical Processes, and Reactions and Reactors * Each chapter includes a set of problems and exercises for the student, key references, and a list of suggestions for further reading * Includes useful appendices, detailing conversion factors, physical and chemical property data, steam tables, mathematical rules, and a list of symbols used * Suitable for course adoption - follows closely curricula used on most bioprocessing and process biotechnology courses at senior undergraduate and graduate levels.

Author : Vijai Singh,Pau Loke Show
Publisher : Springer Nature
Page : 368 pages
File Size : 43,5 Mb
Release : 2023-01-26
Category : Science
ISBN : 9789811979118

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Biomanufacturing for Sustainable Production of Biomolecules by Vijai Singh,Pau Loke Show Pdf

This book elucidates the sustainable production of commercially important biomolecules in medicines, food, and beverage processing, through biological systems, including microorganisms, animal cells, plant cells, tissues, enzymes, and in vitro. It discusses promising technologies for the manipulation of cells including, genetic engineering, synthetic biology, genome editing, and metabolic engineering. The initial chapters of the book introduce topics on biomanufacturing, circular economy, strain design and improvement, upstream and downstream processing. The subsequent chapters cover artificial intelligence-assisted production, designer cell factories, biosensors for monitoring biomolecules, different cells factories, biosynthetic pathways, and genome editing approaches for scale-up biomanufacturing. Lastly, the book discusses the opportunities and challenges of implementing biological systems for the production of biomolecules. ​This book is a valuable source for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand biomanufacturing for the sustainable production of biomolecules.

Author : Madan L. Verma,Anuj K. Chandel
Publisher : Elsevier
Page : 508 pages
File Size : 55,5 Mb
Release : 2019-07-20
Category : Technology & Engineering
ISBN : 9780444643247

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Biotechnological Production of Bioactive Compounds by Madan L. Verma,Anuj K. Chandel Pdf

Biotechnological Production of Bioactive Compounds provides insights on the most recent innovations, trends, concerns, solutions and practical challenges encountered in the fields of enzyme technology and nanobiotechnology for the production of bioactive materials with extra health benefits. As nanobiotechnology has improved the bioactive extraction process significantly, many bioactives, including bioflavonoids, omega-3 fatty acids, biopigments and low calorie sugar substitutes are a pivotal part of the food industry. The book highlights the production of extra health benefits “bioactives’’ from plants and microbes and explains how the extraction efficiency of bioactives molecules improves significantly with the recent advances in nanobiotechnology. Researchers in the fields of biochemical engineering, biotechnology, bioremediation, environmental sustainability and those in pharma industries will find the information in this book very helpful and illuminating. Outlines technological advances in bioactives extraction Covers bioflavonoids, biopigments, omega-3-fatty acids and low sugar substitutes Explains the mechanisms of Green cargo (biogenic nanoparticles) for the delivery of bioactive molecules