Biosafety In The Laboratory

Author : Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council
Publisher : National Academies Press
Page : 237 pages
File Size : 40,6 Mb
Release : 1989-01-01
Category : Science
ISBN : 9780309039758

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Biosafety in the Laboratory by Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Hazardous Biological Substances in the Laboratory,National Research Council Pdf

Biosafety in the Laboratory is a concise set of practical guidelines for handling and disposing of biohazardous material. The consensus of top experts in laboratory safety, this volume provides the information needed for immediate improvement of safety practices. It discusses high- and low-risk biological agents (including the highest-risk materials handled in labs today), presents the "seven basic rules of biosafety," addresses special issues such as the shipping of dangerous materials, covers waste disposal in detail, offers a checklist for administering laboratory safetyâ€"and more.

Author : Centers for Disease Control (U.S.)
Publisher : Unknown
Page : 156 pages
File Size : 46,9 Mb
Release : 1988
Category : Accidents
ISBN : WISC:89030643761

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Biosafety in Microbiological and Biomedical Laboratories by Centers for Disease Control (U.S.) Pdf

Author : World Health Organization
Publisher : World Health Organization
Page : 196 pages
File Size : 46,5 Mb
Release : 2004-12-28
Category : Medical
ISBN : 9241546506

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Laboratory Biosafety Manual by World Health Organization Pdf

This is the third edition of this manual which contains updated practical guidance on biosafety techniques in laboratories at all levels. It is organised into nine sections and issues covered include: microbiological risk assessment; lab design and facilities; biosecurity concepts; safety equipment; contingency planning; disinfection and sterilisation; the transport of infectious substances; biosafety and the safe use of recombinant DNA technology; chemical, fire and electrical safety aspects; safety organisation and training programmes; and the safety checklist.

Author : Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council
Publisher : National Academies Press
Page : 216 pages
File Size : 44,6 Mb
Release : 2012-03-16
Category : Political Science
ISBN : 9780309225762

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Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories by Committee on Anticipating Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories,Board on Life Sciences,Committee on International Security and Arms Control,Division on Earth and Life Studies,Policy and Global Affairs,National Academy of Sciences,National Research Council Pdf

During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High-containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics: Technological options to meet diagnostic, research, and other goals; Laboratory construction and commissioning; Operational maintenance to provide sustainable capabilities, safety, and security; and Measures for encouraging a culture of responsible conduct. Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action.

Author : Dawn P. Wooley,Karen B. Byers
Publisher : John Wiley & Sons
Page : 953 pages
File Size : 52,8 Mb
Release : 2017-02-01
Category : Science
ISBN : 9781683673132

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Biological Safety by Dawn P. Wooley,Karen B. Byers Pdf

Biological safety and biosecurity protocols are essential to the reputation and responsibility of every scientific institution, whether research, academic, or production. Every risk—no matter how small—must be considered, assessed, and properly mitigated. If the science isn't safe, it isn't good. Now in its fifth edition, Biological safety: Principles and Practices remains the most comprehensive biosafety reference. Led by editors Karen Byers and Dawn Wooley, a team of expert contributors have outlined the technical nuts and bolts of biosafety and biosecurity within these pages. This book presents the guiding principles of laboratory safety, including: the identification, assessment, and control of the broad variety of risks encountered in the lab; the production facility; and, the classroom. Specifically, Biological Safety covers protection and control elements—from biosafety level cabinets and personal protection systems to strategies and decontamination methods administrative concerns in biorisk management, including regulations, guidelines, and compliance various aspects of risk assessment covering bacterial pathogens, viral agents, mycotic agents, protozoa and helminths, gene transfer vectors, zooonotic agents, allergens, toxins, and molecular agents as well as decontamination, aerobiology, occupational medicine, and training A resource for biosafety professionals, instructors, and those who work with pathogenic agents in any capacity, Biological safety is also a critical reference for laboratory managers, and those responsible for managing biohazards in a range of settings, including basic and agricultural research, clinical laboratories, the vivarium, field study, insectories, and greenhouses.

Author : World Health Organization
Publisher : Unknown
Page : 132 pages
File Size : 45,6 Mb
Release : 1983
Category : Accidents
ISBN : WISC:89031192651

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Laboratory Biosafety Manual by World Health Organization Pdf

Author : Reynolds M. Salerno,Jennifer Gaudioso
Publisher : CRC Press
Page : 264 pages
File Size : 46,7 Mb
Release : 2015-12-01
Category : Medical
ISBN : 9781498749749

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Laboratory Biorisk Management by Reynolds M. Salerno,Jennifer Gaudioso Pdf

Over the past two decades bioscience facilities worldwide have experienced multiple safety and security incidents, including many notable incidents at so-called "sophisticated facilities" in North America and Western Europe. This demonstrates that a system based solely on biosafety levels and security regulations may not be sufficient. Setting the stage for a substantively different approach for managing the risks of working with biological agents in laboratories, Laboratory Biorisk Management: Biosafety and Biosecurity introduces the concept of biorisk management—a new paradigm that encompasses both laboratory biosafety and biosecurity. The book also provides laboratory managers and directors with the information and technical tools needed for its implementation. The basis for this new paradigm is a three-pronged, multi-disciplinary model of assessment, mitigation, and performance (the AMP model). The application of the methodologies, criteria, and guidance outlined in the book helps to reduce the risk of laboratories becoming the sources of infectious disease outbreaks. This is a valuable resource for those seeking to embrace and implement biorisk management systems in their facilities and operations, including the biological research, clinical diagnostic, and production/manufacturing communities.

Author : National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs
Publisher : National Academies Press
Page : 121 pages
File Size : 47,8 Mb
Release : 2019-05-01
Category : Science
ISBN : 9780309486569

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Developing Norms for the Provision of Biological Laboratories in Low-Resource Contexts by National Academies of Sciences, Engineering, and Medicine,Division on Earth and Life Studies,Board on Life Sciences,Policy and Global Affairs Pdf

On June 27-28, 2018, the U.S. National Academies of Sciences, Engineering, and Medicine (the National Academies) convened an international workshop in Amsterdam, the Netherlands, on developing norms for the provision of laboratories in low-resource contexts. The U.S. Department of State's Biosecurity Engagement Program requested that the National Academies organize this workshop to engage an international group of organizations that provide funding for construction, upgrades, and maintenance of biological laboratories in countries without the means to build such labs themselves. Twenty-one people from 19 organizations participated. The intent was to advance the conversation about the identification and application of guiding principles and common norms for use by these organizations in their grants, partnerships, and aid. This publication summarizes the presentations and discussions from the workshop.

Author : Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner
Publisher : John Wiley & Sons
Page : 0 pages
File Size : 43,5 Mb
Release : 2013-12-04
Category : Science
ISBN : 352733467X

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Working in Biosafety Level 3 and 4 Laboratories by Manfred Weidmann,Nigel Silmann,Patrick Butaye,Mandy Elschner Pdf

The first training manual for new staff working in BSL3/4 labs. This guide is based on a course developed in 2007 by the EU COST action group 28b which serves as a standard for many courses BSL3/4 training courses worldwide. The four-day course consists of lectures and practical training with the lecturers covering all the different possibilities of organising a BSL-3/4 lab including the adaptation to the local requirements of biosafety, safety at work, and social regulations. This book covers bio-containment, hazard criteria and categorisation of microbes, technical specifications of BSL-3 laboratories and ABSL-3 laboratories, personal protective gear, shipping BSL-3 and BSL-4 organisms according to UN and IATA regulations, efficacy of inactivation procedures, fumigation, learning from a history of lab accidents, handling samples that arrive for diagnostic testing and bridging the gap between the requirements of bio-containment and diagnostics. Course participants can not only use the book for their actual training event but it will remain a useful reference throughout their career in BSL3/4 labs.

Author : Reynolds M. Salerno,Jennifer Gaudioso,Benjamin H. Brodsky
Publisher : CRC Press
Page : 208 pages
File Size : 55,6 Mb
Release : 2007-06-21
Category : Science
ISBN : 1420006207

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Laboratory Biosecurity Handbook by Reynolds M. Salerno,Jennifer Gaudioso,Benjamin H. Brodsky Pdf

By achieving a delicate balance between systems and practices, proper laboratory biosecurity reduces the risk of legitimate bioscience facilities becoming sources of pathogens and toxins for malicious use. Effective design and implementation of laboratory biosecurity depends on cooperation among individuals from diverse communities, including scientists, technicians, policy makers, security engineers, and law enforcement officials. Providing guidance to the broad international community, Laboratory Biosecurity Handbook addresses the objectives of biosecurity and the ways in which they overlap or conflict with those of biosafety. The book describes the risks of working with dangerous pathogens and toxins in the current era of international terrorism. The authors characterize the global spread of legitimate biotechnology and relate it to the rise of transnational terrorism, emphasizing the need for biosecurity measures even in legitimate bioscience. The book discusses biosecurity risk assessment-a practical methodology that allows laboratory management and biosafety/biosecurity officers to analyze and determine the level of risk, and serves as a basis for managing those risks. The book includes questionnaires that can assist the process of collecting data for a biosecurity vulnerability assessment, example standard operating procedures and memoranda of understanding, and other useful reference material. Addressing a variety of operating environments and the particular challenges they face when designing and implementing laboratory biosecurity, this book can assist bioscience facilities ranging from the large to the small, from those that focus on diagnosis or vaccine development, to those only minimally involved with infectious diseases. The detailed recommendations help avoid a "one-size-fits-all" approach to security and save limited resources. The book shows institutions how to develop and implement a biosecurity plan, and helps ensure that all components are included in the overall system, whether existing or new.

Author : Canada. Health Canada,Centre for Emergency Preparedness and Response (Canada)
Publisher : Unknown
Page : 134 pages
File Size : 42,8 Mb
Release : 2004
Category : Medical
ISBN : UIUC:30112074022465

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The Laboratory Biosafety Guidelines by Canada. Health Canada,Centre for Emergency Preparedness and Response (Canada) Pdf

These guidelines were developed to guide government, industry, university, hospital, and other public health and microbiological laboratories in their development of biosafety policies and programs. They also provide information and recommendations on the design, construction, and commissioning of containment facilities. The guidelines are intended to reduce the incidence of infection and mortality among laboratory workers, as well as to prevent secondary transmission of disease to the public.

Author : National Committee on Radiation Protection (U.S.)
Publisher : Unknown
Page : 40 pages
File Size : 55,7 Mb
Release : 1949
Category : Dead
ISBN : UOM:39015094999532

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Safe Handling of Radioactive Isotopes by National Committee on Radiation Protection (U.S.) Pdf

Author : National Research Council,Institute of Medicine,Board on Health Sciences Policy,Policy and Global Affairs,Committee on Science, Technology, and Law,Division on Earth and Life Studies,Board on Life Sciences
Publisher : National Academies Press
Page : 140 pages
File Size : 45,5 Mb
Release : 2015-04-13
Category : Science
ISBN : 9780309367868

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Potential Risks and Benefits of Gain-of-Function Research by National Research Council,Institute of Medicine,Board on Health Sciences Policy,Policy and Global Affairs,Committee on Science, Technology, and Law,Division on Earth and Life Studies,Board on Life Sciences Pdf

On October 17, 2014, spurred by incidents at U.S. government laboratories that raised serious biosafety concerns, the United States government launched a one-year deliberative process to address the continuing controversy surrounding so-called "gain-of-function" (GOF) research on respiratory pathogens with pandemic potential. The gain of function controversy began in late 2011 with the question of whether to publish the results of two experiments involving H5N1 avian influenza and continued to focus on certain research with highly pathogenic avian influenza over the next three years. The heart of the U.S. process is an evaluation of the potential risks and benefits of certain types of GOF experiments with influenza, SARS, and MERS viruses that would inform the development and adoption of a new U.S. Government policy governing the funding and conduct of GOF research. Potential Risks and Benefits of Gain-of-Function Research is the summary of a two-day public symposia on GOF research. Convened in December 2014 by the Institute of Medicine and the National Research Council, the main focus of this event was to discuss principles important for, and key considerations in, the design of risk and benefit assessments of GOF research. Participants examined the underlying scientific and technical questions that are the source of current discussion and debate over GOF research involving pathogens with pandemic potential. This report is a record of the presentations and discussion of the meeting.

Author : Anonim
Publisher : Unknown
Page : 64 pages
File Size : 45,6 Mb
Release : 1995
Category : Electronic
ISBN : MINN:31951D00274926X

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Primary Containment for Biohazards by Anonim Pdf

Author : Department of Health and Human Services
Publisher : Lulu.com
Page : 438 pages
File Size : 44,5 Mb
Release : 2016-04-29
Category : Reference
ISBN : 1365080897

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Biosafety in Microbiological and Biomedical Laboratories by Department of Health and Human Services Pdf

Biosafety in Microbiological and Biomedical Laboratories (BMBL) quickly became the cornerstone of biosafety practice and policy in the United States upon first publication in 1984. Historically, the information in this publication has been advisory is nature even though legislation and regulation, in some circumstances, have overtaken it and made compliance with the guidance provided mandatory. We wish to emphasize that the 5th edition of the BMBL remains an advisory document recommending best practices for the safe conduct of work in biomedical and clinical laboratories from a biosafety perspective, and is not intended as a regulatory document though we recognize that it will be used that way by some. This edition of the BMBL includes additional sections, expanded sections on the principles and practices of biosafety and risk assessment; and revised agent summary statements and appendices. We worked to harmonize the recommendations included in this edition with guidance issued and regulations...